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Alzheimer's disease & dementia

Native California medicinal plant may hold promise for treating Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead ...

Cancer

New 'smart drug' shows promise for metastatic triple-negative breast cancer

A new "smart drug" has shown promise for women with metastatic triple-negative breast cancer, based on data from a clinical trial at NewYork-Presbyterian/Columbia's Herbert Irving Comprehensive Cancer Center and other centers. ...

Cancer

Study finds way to potentially improve immunotherapy for cancer

A new study has identified a drug that potentially could make a common type of immunotherapy for cancer even more effective. The study in laboratory mice found that the drug dasatinib, which is FDA-approved to treat certain ...

HIV & AIDS

New insight on potent HIV antibody could improve vaccine design

In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus's outer envelope where a lineage of antibodies are able to dock and neutralize the ...

Diabetes

Viruses that linger in the gut could trigger type 1 diabetes

Researchers at the Center for Infection and Immunity (CII) at the Columbia University Mailman School of Public Health and the University of New South Wales, Sydney, Australia, provide new evidence supporting an association ...

Medical research

Young bone marrow rejuvenates aging mouse brains, study finds

A new study has found that transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities. The findings support an emerging ...

Medical research

Researchers define cells used in bone repair

Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair.

Health

High-fat diets do no favors for your gut bacteria

(HealthDay)—Has a high-fat meal ever left you feeling bloated and sluggish? It turns out that a heavier fat diet may keep the many bacteria that live in your digestive system from doing their best, too.

Genetics

Gene therapy durably reverses congenital deafness in mice

In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France, Sorbonne University and the University of Clermont Auvergne have restored ...

Neuroscience

Scientists create new map of brain's immune system

A team of researchers under the direction of the Medical Center—University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice. The scientists demonstrated for the first time ...

Neuroscience

Can a nerve injury trigger ALS?

A growing collection of anecdotal stories raises the possibility that nerve injury in an arm or a leg can act as a trigger for the development amyotrophic lateral sclerosis, or ALS—a progressive neurodegenerative disease ...