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Oncology & Cancer

Researchers unveil experimental compound to block therapeutic target in blood cancer

Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer. They also developed an experimental therapeutic to block ...

Cardiology

Evolutionary gene loss may help explain why only humans are prone to heart attacks

Researchers at University of California San Diego School of Medicine say the loss of a single gene two to three million years ago in our ancestors may have resulted in a heightened risk of cardiovascular disease in all humans ...

Genetics

Study finds Nunavik Inuit are genetically unique

A new study has found that an Inuit population in Canada's Arctic are genetically distinct from any known group, and certain genetic variants are correlated with brain aneurysm.

Genetics

Genes linked to death from sepsis identified in mice

Sepsis is a life-threatening condition that occurs when the body's immune response to infection spirals out of control. Bacteria in the bloodstream trigger immune cells to release powerful molecules called cytokines to quickly ...

Medical research

Encephalitis identified as rare toxicity of immunotherapy treatment

After a cancer patient receiving an immunotherapy developed encephalitis and died 18 months into treatment, researchers at Vanderbilt-Ingram Cancer Center (VICC) investigated why the complication occurred, performing a molecular ...

Medical research

Gut microbes may affect the course of ALS

Researchers at the Weizmann Institute of Science have shown in mice that intestinal microbes, collectively termed the gut microbiome, may affect the course of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's ...

Medical research

Toxin responsible for Legionella growth identified

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps ...

Neuroscience

Fruit flies find their way by setting navigational goals

When a fruit fly decides it wants to walk in a particular direction, it sticks to its plan with impressive resolve. Now, Rockefeller scientists have begun to understand how insect brains make and meet navigational goals.

Neuroscience

Quantifying how the brain smells

Scientists haven't quite decoded how animals smell, but researchers at Cold Spring Harbor Laboratory (CSHL) found that it's different from previously thought.

Diseases, Conditions, Syndromes

New opportunities for treating kidney failure

Our kidneys can sense when we need them to work a bit harder. As the intestines begin to produce more waste products, the kidneys start to work harder to excrete them. Researchers at, among others, Utrecht University and ...

Health

Heart disease biomarker linked to paleo diet

People who follow the paleo diet have twice the amount of a key blood biomarker linked closely to heart disease, the world's first major study examining the impact of the diet on gut bacteria has found.

Oncology & Cancer

Overstuffed cancer cells may have an Achilles' heel

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry ...

Medications

Old vaccine brings new surprises

New research about an old vaccine—one that has been in use for nearly 100 years—has not only shown how effective it is but also suggests it improves our immune response to a wider range of bacteria than originally intended.