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Oncology & Cancer
Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer
Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival for the disease. However, ...
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Medical research
Trial demonstrates one-year progression-free survival in 94% of patients with stage 3 or 4 classic Hodgkin lymphoma
A Phase 3 trial has demonstrated that patients with advanced stage (3 or 4) classic Hodgkin lymphoma who underwent initial treatment with nivolumab, a PD-1 checkpoint inhibitor, and AVD chemotherapy (N-AVD) had a significantly ...
9 hours ago
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Medical research news
Genetic variants may affect treatment response to commonly prescribed type 2 diabetes medication
Various medications can be prescribed to lower blood sugar levels in individuals at high risk for developing type 2 diabetes, but it's often unclear which patients will benefit most from which drugs.
Jun 3, 2023
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Experts warn bird flu virus changing rapidly in largest ever outbreak
The virus causing record cases of avian influenza in birds across the world is changing rapidly, experts have warned, as calls increase for countries to vaccinate their poultry.
Jun 3, 2023
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US life expectancy disadvantage is worse than previously believed, according to new study
When it comes to public health, the United States is at a disadvantage compared with other developed countries. Americans experience more illness, have less access to health care and pay more for health services than citizens ...
Jun 2, 2023
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Wharton's jelly found to halt diabetes progression in Phase II trial
Research in Sweden led by the University of Uppsala has looked into using mesenchymal stromal cells to halt the progress of newly diagnosed type 1 diabetes. In the paper, "Umbilical cord-derived mesenchymal stromal cells ...
Study links post surgery mobility to favorable outcomes
Research led by the Cleveland Clinic in Ohio evaluated postoperative recovery rates from elective surgery in a study, "Association Between Mobilization and Composite Postoperative Complications Following Major Elective Surgery," ...
How does the brain process memory during sleep? New study offers clues
While it's long been suspected that our brains consolidate each day's events as we sleep, a new study is the first to show that process in action.
Jun 2, 2023
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Study helps explain what drives psoriasis severity and offers clues as to how disease may spread to other body parts
Beneath and beyond the reddish, flaky lesions that form in the skin of those with psoriasis, mild and severe forms of the disease can be told apart by the activity of key cells and signaling pathways, a new study shows.
Jun 2, 2023
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Children with drug-resistant epilepsy live longer after cranial surgery, large study finds
Survival rate beyond 10 years in children with drug-resistant epilepsy (DRE) was highest after cranial epilepsy surgery and lowest when treated only with antiseizure medications, according to a study published in The Lancet ...
Jun 2, 2023
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For advanced, HER2-amplified bile duct cancers, antibody treatment trial shows promising results
Bile duct cancers are uncommon and aggressive types of gastrointestinal cancer. They include cholangiocarcinomas, which can form inside or outside of the liver, as well as cancers of the gallbladder, and are highly likely ...
Jun 2, 2023
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'Tipping the balance' of immune cells from bad to good reverses multiple sclerosis symptoms in mice
According to the federal government's National Institute of Neurological Disorders and Stroke, nearly 3 million people worldwide—with almost a third in the United States—are living with multiple sclerosis (MS), a disabling ...
Jun 2, 2023
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Breast cancer drug shown to reduce recurrence risk
Even when the disease is caught early, breast cancer recurrence is relatively commonplace—and for survivors, the prospect can be daunting.
Jun 2, 2023
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Scientists reveal new details of cellular process that prevents spread of cancer
Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.
Jun 2, 2023
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Want to know how processed your food is? There's an algorithm for that
Northeastern researchers have been busy trying to better understand the links between "ultra-processed foods" and human health through the university-sponsored Foodome project.
Jun 2, 2023
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Immunotherapy for brain cancer metastases shows clinical benefit
In a phase 2 clinical trial of the immune checkpoint inhibitor pembrolizumab, investigators found that 42 percent of patients with metastatic brain cancer benefited from the therapy, with seven patients in the trial surviving ...
Jun 2, 2023
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Memory killer cells can improve survival for melanoma patients
Our skin contains specialized long-lived killer cells that protect against intruders. Researchers at Karolinska Institutet in Sweden have now identified how these cells are formed, and shown that high levels of memory killer ...
Jun 2, 2023
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Poorly insulated nerve cells shown to promote Alzheimer's disease in old age
Alzheimer's disease, an irreversible form of dementia, is considered the world's most common neurodegenerative disease. The prime risk factor for Alzheimer's is age, although it remains unclear why. It is known that the insulating ...
Jun 2, 2023
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Overdoses and deaths related to substance use didn't increase after a large-scale prison release, shows study
Contrary to expectations, the risk for relapses, overdoses and deaths related to substance use disorder didn't increase after a large-scale prison release in New Jersey, according to a Rutgers study.
Jun 2, 2023
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Single-cell dissection of Alzheimer's vascular changes across six brain regions
Your brain is powered by 400 miles of blood vessels that provide nutrients, clear out waste products, and form a tight protective barrier—the blood brain barrier—that controls which molecules can enter or exit. However, ...
Jun 2, 2023
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