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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
Central trafficking compartment in neurons malfunctions in majority of Alzheimer's patients
Decades before the first symptoms of Alzheimer's appear, the brain's neurons start secreting tau proteins, one of the first changes known to occur in the course of the disease.
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Alzheimer's disease & dementia
Team uses copper to image Alzheimer's aggregates in the brain
A proof-of-concept study conducted in a mouse model of Alzheimer's disease offers new evidence that copper isotopes can be used to detect the amyloid-beta protein deposits that form in the brains of people living with—or ...
Nov 24, 2020
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Potential new therapies for Alzheimer's are revealed through network modeling of its complex molecular interactions
Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer's Disease (LOAD), as well as a promising therapeutic candidate ...
Nov 24, 2020
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Anxiety associated with faster Alzheimer's disease onset
Anxiety is associated with an increased rate of progression from mild cognitive impairment to Alzheimer's disease, according to a study being presented at the annual meeting of the Radiological Society of North America (RSNA).
Nov 24, 2020
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Early, late stages of degenerative diseases are distinct, study shows
Rice University biochemists Michael Stern and James McNew have studied how neurodegeneration kills cells. They've conducted countless experiments over more than a decade, and they've summarized all they've learned in a simple ...
Nov 23, 2020
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Team discovers new connection between Alzheimer's dementia and Dlgap2
A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer's dementia and cognitive decline, according to a national research team led by The ...
Nov 23, 2020
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Early signs of Alzheimer's disease in people with Down's syndrome
Researchers at Karolinska Institutet in Sweden have studied the incidence and regional distribution of Alzheimer's disease biomarkers in the brains of people with Down's syndrome. The results can bring new possibilities for ...
Nov 23, 2020
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The danger of Z-drugs for dementia patients
Strong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—according to research from the University of East Anglia.
Nov 23, 2020
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Football and dementia: heading must be banned until the age of 18
Alarm bells are ringing in sport about the risk of a group of chronic, neuro-degenerative diseases, commonly understood as dementia. There is an increasingly large body of evidence which has identified that small, repetitive ...
Nov 23, 2020
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Tau protein changes correlate with Alzheimer's disease dementia stage
Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes ...
Nov 19, 2020
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Found: A genetic link to molecular events that precede symptoms in Alzheimer's disease
Researchers at Tufts University School of Medicine have discovered a molecular mechanism that causes a "traffic jam" of enzymes traveling up and down neuronal axons, leading to the accumulation of amyloid beta—a key feature ...
Nov 18, 2020
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Does air pollution increase women's risk of dementia?
Older women who live in locations with higher levels of air pollution may have more brain shrinkage, the kind seen in Alzheimer's disease, than women who live in locations with lower levels, according to a new study published ...
Nov 18, 2020
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Lesbian, gay, bisexual communities more at-risk for dementia, study finds
Lesbian, gay and bisexual—or LGB—people are more vulnerable to one of the fastest-growing health concerns in the country: dementia, according to new research from Michigan State University.
Nov 18, 2020
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Diabetes increases neuritic damage around amyloid plaques in Alzheimer's disease
New research from the University of Eastern Finland explores the role of diabetes in the cellular and molecular changes underlying Alzheimer's disease (AD). In an AD mouse model, diabetes induced through a diet rich in fats ...
Nov 18, 2020
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Researchers find dementia starts much earlier than previously assumed
Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers including Mathias Jucker ...
Nov 17, 2020
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New potential clues in diagnosing, treating Alzheimer's found in retinas
A study led by the Cedars-Sinai Department of Neurosurgery has identified certain regions in the retina—the lining found in the back of the eye—that are more affected by Alzheimer's disease than other areas. The findings ...
Nov 17, 2020
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Scientists succeed in reducing the levels of the molecules that kill neurons in elderly mice with Alzheimer's
Alzheimer's disease is the most common dementia worldwide and it is characterized by learning impairment, memory loss, disorientation and anxiety, among other behavioral and psychological symptoms. Since Alois Alzheimer described ...
Nov 16, 2020
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Actively speaking two languages protects against cognitive decline
In addition to enabling us to communicate with others, languages are our instrument for conveying our thoughts, identity, knowledge, and how we see and understand the world. Having a command of more than one enriches us and ...
Nov 16, 2020
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Most Medicare beneficiaries say they don't receive cognitive assessments
New research from the University of Southern California measured the use of Medicaid's annual wellness visits and the receipt of structured cognitive assessments among Medicaid beneficiaries.
Nov 16, 2020
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Overly reactivated star-shaped cells explain the unpredictability of Alzheimer's disease
Though Alzheimer's disease (AD) is a common and fatal neurodegenerative brain disorder, most AD treatments are not making much headway in adressing its cause. Many AD drugs have targeted the elimination of beta-amyloid (Aβ) ...
Nov 16, 2020
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