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Alzheimer's disease & dementia news

Alzheimer's disease & dementia

Scientists identify cell vulnerability 'fingerprint' related to Parkinson's, Lewy body dementia

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

Neuroscience

New mechanism uncovered in early stages of Alzheimer's disease

Alzheimer's disease (AD) remains one of the most challenging and prevalent neurodegenerative disorders, affecting millions of individuals worldwide. In a new study published in Developmental Cell, researchers from the lab ...

Alzheimer's disease & dementia

A new diagnostic model offers hope for Alzheimer's

A new mathematical model offers hope for better prediction and treatment of Alzheimer's disease. Most mathematical models of Alzheimer's are theoretical, focusing on short term molecular and cellular-level changes that cannot ...

Genetics

Newly found genetic variant defends against Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease. The study, "Rare ...

Alzheimer's disease & dementia

Human neuron model paves the way for new Alzheimer's therapies

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer's disease ...

Neuroscience

Untangling the threads of early onset dementia

Changes in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementia in patients under the age of 65, which is associated with degeneration of the frontal and temporal ...

Alzheimer's disease & dementia

Immunotherapy for Alzheimer's disease shows promise in mouse study

Alzheimer's disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline. The new generation of Alzheimer's ...