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Alzheimer's disease & dementia news
Neuroscience
Novel AI method sheds light on how enzyme linked to Alzheimer's selects its targets
Researchers from DZNE, Ludwig-Maximilians-Universität München (LMU), and Technical University of Munich (TUM) have found that the enzyme "gamma-secretase"—implicated in Alzheimer's disease and cancer—selects its reaction ...
7 hours ago
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Genetics
A 'Google Maps' for tau movement sheds light on why some brain regions resist Alzheimer's
It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau—a protein known to misbehave—plays an important role in the disease. Normally, tau helps stabilize neurons, but ...
8 hours ago
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Why are women twice as likely to develop Alzheimer's as men?
A neglected piece of the Alzheimer's puzzle has been getting increased scientific attention: why women are twice as likely as men to develop the disease.
Jul 8, 2025
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People diagnosed with dementia are living longer, global study shows
A person diagnosed with dementia has improved survival outcomes in recent years amid significant progress in dementia diagnosis and care, according to a recent multinational study led by a University of Waterloo researcher.
Jul 8, 2025
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ADAM10 protein levels in blood linked to early Alzheimer's and genetic risk factors
Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, are developing a panel of biomarkers for the early detection of Alzheimer's disease and for distinguishing it from other types ...
Jul 8, 2025
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Dementia protection linked to where the body lies—belly fat a risk factor
Men with high levels of belly fat are at increased risk of dementia, according to a new study by Monash University researchers of more than 17,000 individuals aged 65 to 98 years in the ASPREE Study.
Jul 8, 2025
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Elderly people with dementia being subjected to violence, abuse and neglect in their own homes
There's a clear downside to the Norwegian policy that encourages allowing elderly people to live at home for as long as possible. Caring for the aging population has been left to worn-out family members.
Jul 8, 2025
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New study maps four key pathways to Alzheimer's disease
UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated ...
Jul 7, 2025
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New blood biomarker predicts progression of Alzheimer's disease even in its earliest stages
A team of researchers at the Sant Pau Research Institute (IR Sant Pau) has demonstrated that the plasma biomarker p-tau217, obtained through a simple blood test, can predict the clinical progression of Alzheimer's disease ...
Jul 7, 2025
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Death of a partner and financial stress linked to increased risk of Alzheimer's disease, differences in brain structure
Stressful life events can negatively impact brain health. Specifically, grief over the loss of a partner has been linked to alterations in biological processes associated with Alzheimer's disease, while unemployment and financial ...
Jul 3, 2025
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First large-scale stem cell bank enables worldwide studies on genetic risk for Alzheimer's disease
Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10% of people over the age of 65 and one third of people aged 85 and above. Besides environmental factors, the genes have a strong ...
Jul 3, 2025
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Blood stem cell mutations linked to lower risk of late-onset Alzheimer's disease
A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset Alzheimer's disease.
Jul 2, 2025
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Resilience and perceived gains can shape mental health in dementia caregivers
University of Tennessee assistant professor Dr. Fei Wang's latest research, published in Research on Aging, uncovers how resilience plays a key role in shaping mental health outcomes among U.S. caregivers—especially distinguishing ...
Jul 1, 2025
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Discovery of key brain repair mechanism in vascular dementia reveals promising therapeutic target
A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional ...
Jun 30, 2025
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Low-intensity brain stimulation may restore neuron health in Alzheimer's disease
Alzheimer's disease (AD) is a debilitating neurodegenerative condition that affects a significant proportion of older people worldwide. Synapses are points of communication between neural cells that are malleable to change ...
Jun 30, 2025
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Cough medicine Ambroxal shows potential to slow Parkinson's-related dementia
Dementia poses a major health challenge with no safe, affordable treatments to slow its progression. Researchers at Lawson Research Institute (Lawson), the research arm of St. Joseph's Health Care London, are investigating ...
Jun 30, 2025
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An exercise drug? Harnessing the cognitive benefits of a workout for Alzheimer's patients with mobility issues
For years, researchers have seen a connection between exercise and the progression of cognitive disorders such as Alzheimer's—but ramping up movement isn't possible for many patients. A new study published in Nature Neuroscience ...
Jun 29, 2025
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AI tool detects 9 types of dementia from a single brain scan
Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer's disease, using a single, widely ...
Jun 28, 2025
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Brain imaging benchmark could better classify Alzheimer's disease-related changes
A team of researchers from the Keck School of Medicine of USC's Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) has identified a new brain imaging benchmark that may improve how researchers classify ...
Jun 27, 2025
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Vaccine for RSV shown to reduce the risk of dementia
A new study by the University of Oxford, published in the journal npj Vaccines, shows that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk in the following 18 months. ...
Jun 26, 2025
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Blood test shows promise for early dementia with Lewy Bodies diagnosis
A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...
Jun 26, 2025
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Study reveals how Alzheimer's disease and attention shape our ability to remember
Why do some older adults easily remember the name of a new acquaintance or the location of their keys, while others struggle with everyday recall—despite appearing equally healthy?
Jun 25, 2025
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Critical brain link could explain how Alzheimer's takes hold
A crucial link between the brain's cleaning system and deterioration of neurons associated with Alzheimer's disease has been discovered by University of Queensland researchers.
Jun 25, 2025
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Dementia cells' misplaced genetic messages may be re-established by drug currently in clinical trials
Researchers at the Francis Crick Institute and UCL have shown that genetic messages are misplaced in nerve cells in a model of Alzheimer's disease and frontotemporal dementia. These messages mostly affect the function of ...
Jun 25, 2025
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Space-based experiment opens new avenues in Alzheimer's research
A collaborative team of researchers has succeeded in revealing the high-resolution structures of amyloid β (Aβ40) fibrils carrying the Tottori-type familial mutation (D7N) by leveraging the microgravity environment aboard ...
Jun 25, 2025
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