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Alzheimer's disease & dementia news
Neuroscience
How the cheese-noodle principle could help counter Alzheimer's
Researchers at the Paul Scherrer Institute PSI have clarified how spermine—a small molecule that regulates many processes in the body's cells—can guard against diseases such as Alzheimer's and Parkinson's: It renders ...
11 hours ago
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Alzheimer's disease & dementia
Targeting brain immune cells could restore Alzheimer's-related lipid imbalance, research shows
More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid‐beta (amyloid) plaques and tau protein tangles. These observations ...
10 hours ago
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Arginine supplementation curbs Alzheimer's disease pathology in animal models
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) ...
3 hours ago
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Astrocytes clear amyloid plaques and preserve cognitive function in Alzheimer's mouse models
Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer's disease and preserves cognitive function. The mechanism involves ...
16 hours ago
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Genetic risk combined with cardiovascular factors may help predict and delay dementia
Combining genetic risk with cardiovascular disease risk factors—such as high LDL cholesterol, obesity, and hypertension—may predict who is more likely to develop dementia, according to a new study led by UC San Francisco.
8 hours ago
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Simple blood test may someday allow for diagnosis of LATE dementia during life
Jijing Wang, Ph.D., and Hyun-Sik Yang, MD, of the Department of Neurology at Mass General Brigham, are the lead and senior authors of a paper published in Molecular Neurodegeneration titled "Plasma TDP-43 is a potential biomarker ...
23 hours ago
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Long-term pharmacological treatment shows promise against memory impairments in Down syndrome
In 2019, a research group led by Andrés Ozaita, of the Department of Medicine and Life Sciences at Pompeu Fabra University, described that mice models for Down syndrome have more cannabinoid receptor 1 (CBR1) in some regions ...
Nov 20, 2025
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Exercising in mid and later life can reduce dementia risk, new study suggests
For years, scientists have known that moving our bodies can sharpen our minds. Physical activity boosts blood flow to the brain, enhances neuroplasticity and reduces chronic inflammation. These processes are believed to protect ...
Nov 20, 2025
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Staying connected: How social ties can protect aging brains
"Social frailty" is a major dementia risk. A UNSW researcher is changing how to spot and treat it early.
Nov 20, 2025
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Microglia modulate the reactivity of astrocytes in Alzheimer's disease, study finds
Alzheimer's disease (AD) is a highly debilitating neurodegenerative disease characterized by the progressive loss of memory and decline of mental functions. Earlier research has uncovered some of the neural and biological ...
Clogged 'drains' in the brain likely an early-warning sign of Alzheimer's disease
"Drains" in the brain, responsible for clearing toxic waste in the organ, tend to get clogged up in people who show signs of developing Alzheimer's disease, a study by researchers from Nanyang Technological University, Singapore ...
Nov 19, 2025
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Investigating lithium's potential role in slowing cognitive decline in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline such as memory loss and behavioral disturbances that severely impair quality of life. Despite decades of research, effective ...
Nov 19, 2025
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Study links depression, insomnia to higher risk of dementia
A study conducted by researchers at Saint Louis University found that people over 50 who suffer from both depression and insomnia are significantly more likely to develop Alzheimer's disease and related dementias.
Nov 19, 2025
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Muscle protein linked to exercise opens new way to treat Alzheimer's
Alzheimer's disease (AD) is a devastating cause of memory loss and cognitive decline, for which no curative treatment is available. Among lifestyle factors, physical activity stands out as possibly one of the strongest defenders ...
Nov 18, 2025
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Shingles vaccine most promising common drug to potentially prevent Alzheimer's
A new study has identified three existing medications that could be repurposed to treat or prevent Alzheimer's disease.
Nov 18, 2025
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Gene 'switch' reverses Alzheimer's risk in experimental model
University of Kentucky researchers have developed a new experimental model that could point the way toward more effective Alzheimer's disease treatments by targeting one of the brain's most important genes for risk and resilience.
Nov 17, 2025
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What polymers can teach us about curing Alzheimer's disease
Researchers from Tokyo Metropolitan University have applied ideas from polymer physics to illuminate the mechanism behind a key pathology in Alzheimer's disease, the formation of fibrils of tau proteins. They showed that ...
Nov 17, 2025
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Mild cognitive impairment, dementia risk up with increasing biological severity of Alzheimer's disease
For individuals who are currently cognitively unimpaired, the lifetime and 10-year absolute risk of mild cognitive impairment (MCI) and dementia increases with increasing amyloid positron emission tomography (PET) centiloid ...
Nov 17, 2025
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Study shows over 90% of older adults with dementia undergo burdensome interventions in their final year
A new study by researchers from Duke-NUS Medical School has revealed that almost all community-dwelling older adults with advanced dementia in Singapore experience at least one potentially burdensome intervention in their ...
Nov 17, 2025
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Poor sleep may nudge the brain toward dementia, researchers find
Staring at the ceiling while the clock blinks 3am doesn't only sap energy for the next day. A large, long-running U.S. study of older adults has now linked chronic insomnia to changes inside the brain that set the stage for ...
Nov 16, 2025
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How to keep dementia from robbing your loved ones of their sense of personhood—tips for caregivers
Every three seconds, someone in the world develops dementia. There are over 6 million people living with dementia in the U.S. and 57 million globally.
Nov 16, 2025
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How income may shape risk of dementia
People with lower incomes and people from racial and ethnic historically underrepresented groups in clinical studies are more likely to have modifiable risk factors for dementia, factors that could be changed to lower their ...
Nov 13, 2025
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Chemical compound holds potential against Alzheimer's disease
A team of researchers at the Federal University of ABC (UFABC) in Brazil has developed a new chemical compound with the potential to treat Alzheimer's disease. The research involved computer simulations (in silico), cell ...
Nov 12, 2025
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Alzheimer's risk calculator could spot danger years before symptoms begin
Mayo Clinic researchers have developed a new tool that can estimate a person's risk of developing memory and thinking problems associated with Alzheimer's disease years before symptoms appear.
Nov 12, 2025
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New oral treatment may prevent dementia
Researchers from DANDRITE have played a central role in developing a new oral treatment that, for the first time ever, has shown promising results in a clinical trial involving patients—a breakthrough that appears capable ...
Nov 12, 2025
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