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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
Alzheimer's disease more prevalent in older people than previously thought
New research, published in Nature, has provided the first ever population-based data on the frequency of Alzheimer's disease neuropathological changes (ADNC)—a key causal factor behind the development of dementia—and ...
2 hours ago
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Neuroscience
How an antiviral defense mechanism may lead to Alzheimer's disease
One of the main proteins that contributes to Alzheimer's disease is called phospho-tau (p-tau). When p-tau gets too many phosphate groups attached to it (a process called hyperphosphorylation), it starts to stick together ...
10 hours ago
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New details on role of fat transport molecules in Alzheimer's onset
A new study presents robust evidence on the role of lysophosphatidylcholines (LPCs) in the onset of Alzheimer's disease. Researchers discovered that LPCs—compounds that transport a variety of healthy fatty acids to the ...
10 hours ago
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Concurrent frailty and depression likely boost dementia risk in older people
Concurrent physical frailty and depression likely boost the risk of dementia in older people, with the interaction of these two factors alone contributing around 17% of the overall risk, suggest the findings of a large international ...
21 hours ago
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Why a mild brain injury can trigger Alzheimer's
New research from the University of Virginia School of Medicine is revealing why traumatic brain injury increases the chance of developing Alzheimer's disease—and the discovery is pointing to a potential strategy to prevent ...
Dec 16, 2025
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Quality of carbohydrates in diet may play key role in prevention of dementia
The quality and quantity of carbohydrates in the diet play a decisive role in the development of dementias. This is according to a combined study carried out by the Nutrition and Metabolic Health (NuMeH) research group of ...
Dec 16, 2025
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Stroke and dementia: Combating loss of function in small vessels of the brain
A new study identifies molecular factors that promote small vessel disease—and an active drug that can restore impaired vascular functions.
Dec 16, 2025
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Digital tools can improve dementia care—for people with dementia aging in place and their caregivers
Digital technology is ever-present in how we operate in daily life, particularly to connect with others. While touted as a suitable alternative in place of in-person interactions, it has previously been unclear if the same ...
Dec 16, 2025
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Specific depressive symptoms in midlife linked to increased dementia risk
Six particular depressive symptoms when experienced in midlife predict dementia risk more than two decades later, finds a new study led by University College London (UCL) researchers.
Dec 15, 2025
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Study establishes practical definition for rapidly progressive dementia
A new multicenter study led by Mayo Clinic researchers has established a practical, evidence-based definition of rapidly progressive dementia (RPD), a rare but devastating form of cognitive decline that develops over months ...
Dec 15, 2025
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Framework can improve Alzheimer's treatment efficacy by tracking anti-Aβ therapy response
In the last few years, progress has been made in the fight against Alzheimer's disease with a class of therapies called anti-amyloid antibodies (anti-Aβ). These monoclonal anti-Aβs are proteins made in a laboratory to stimulate ...
Dec 12, 2025
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Brain stimulation during sleep boosts weak memories in mice
Manipulating mouse brains during sleep improved their ability to remember new experiences that would normally be forgotten—a finding with important implications for treating Alzheimer's disease and other forms of dementia ...
Dec 11, 2025
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AI tool can detect missed Alzheimer's diagnoses while reducing disparities
Researchers at UCLA have developed an artificial intelligence tool that can use electronic health records to identify patients with undiagnosed Alzheimer's disease, addressing a critical gap in Alzheimer's care: significant ...
Dec 11, 2025
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Plasma p-tau217 can reliably detect preclinical Alzheimer disease
Plasma phosphorylated tau 217 (p-tau217) can reliably detect Alzheimer disease (AD) pathology in the preclinical stage, according to a meta-analysis published online Dec. 1 in JAMA Neurology.
Dec 11, 2025
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Transfusing blood from old mice accelerates Alzheimer's progression in an animal model
Alzheimer's disease is the most common form of dementia worldwide and continues to be one of the greatest public health challenges. New research, published in the journal Aging, reveals that blood from aged mice can accelerate ...
Dec 11, 2025
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Engineers decode dementia type using AI and EEG brainwave analysis
Dementia is a group of disorders that gradually impair memory, thinking and daily functioning. Alzheimer's disease (AD), the most common form of dementia, affects about 7.2 million Americans aged 65 and older in 2025. Frontotemporal ...
Dec 10, 2025
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Your digital twin might save your life
When neurologist Steven Arnold is deciding whether to treat an Alzheimer's patient with a new therapy, he relies on averages.
Dec 9, 2025
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Dual-action arts and well-being program transforms dementia care
A new arts and well-being program co-developed by the University of South Australia, Flinders University and the University of Adelaide shows that supporting the social needs of people living with dementia and their caregivers ...
Dec 9, 2025
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Those who care for family members with Alzheimer's experience poorer health and increased cellular aging
Brittany Butts understands that for many families, Alzheimer's comes as a double burden. As a teenager, she watched not only her grandmother's mental decline from the disease but also her aunt's struggles as the primary caregiver.
Dec 8, 2025
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Study exposes hidden Alzheimer's 'hot spots' in rural Maryland
A new statewide spatial analysis of Alzheimer's disease and related dementias (ADRD) has uncovered significant disparities in Maryland's rural communities, offering a striking example of how health care accessibility is shaping ...
Dec 8, 2025
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Loss of brain protein eases Alzheimer's symptoms and brain damage in mice
New research published in the journal eNeuro examined whether eliminating a protein that is elevated in the brains of those with Alzheimer's could prevent or reduce damage and behavioral symptoms in a mouse model of Alzheimer's ...
Dec 5, 2025
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Alzheimer's changes appear early in patients with Down syndrome
Down syndrome is caused by an extra copy of chromosome 21. Because of genes present on this chromosome that are known to contribute to Alzheimer's disease, patients with Down syndrome often develop the disease, sometimes ...
Dec 5, 2025
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Single enzyme failure found to drive neuron loss in dementia
Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis. The study provides ...
Dec 4, 2025
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Poor kidney health linked to higher levels of Alzheimer's biomarkers in blood
People with impaired kidney function have higher levels of Alzheimer's biomarkers in their blood, but not an increased risk of dementia, according to a study published in Neurology.
Dec 3, 2025
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Just 20 minutes of exercise twice a week may help slow dementia, study finds
How much physical activity—and how often—is needed to help stall dementia? For older adults with mild cognitive decline, there is now an answer: at least 20 minutes, at least twice weekly.
Dec 3, 2025
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