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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
Muscle protein linked to exercise opens new way to treat Alzheimer's
Alzheimer's disease (AD) is a devastating cause of memory loss and cognitive decline, for which no curative treatment is available. Among lifestyle factors, physical activity stands out as possibly one of the strongest defenders ...
7 hours ago
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Gene 'switch' reverses Alzheimer's risk in experimental model
University of Kentucky researchers have developed a new experimental model that could point the way toward more effective Alzheimer's disease treatments by targeting one of the brain's most important genes for risk and resilience.
Nov 17, 2025
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What polymers can teach us about curing Alzheimer's disease
Researchers from Tokyo Metropolitan University have applied ideas from polymer physics to illuminate the mechanism behind a key pathology in Alzheimer's disease, the formation of fibrils of tau proteins. They showed that ...
Nov 17, 2025
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Mild cognitive impairment, dementia risk up with increasing biological severity of Alzheimer's disease
For individuals who are currently cognitively unimpaired, the lifetime and 10-year absolute risk of mild cognitive impairment (MCI) and dementia increases with increasing amyloid positron emission tomography (PET) centiloid ...
Nov 17, 2025
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Study shows over 90% of older adults with dementia undergo burdensome interventions in their final year
A new study by researchers from Duke-NUS Medical School has revealed that almost all community-dwelling older adults with advanced dementia in Singapore experience at least one potentially burdensome intervention in their ...
Nov 17, 2025
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Poor sleep may nudge the brain toward dementia, researchers find
Staring at the ceiling while the clock blinks 3am doesn't only sap energy for the next day. A large, long-running U.S. study of older adults has now linked chronic insomnia to changes inside the brain that set the stage for ...
Nov 16, 2025
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How to keep dementia from robbing your loved ones of their sense of personhood—tips for caregivers
Every three seconds, someone in the world develops dementia. There are over 6 million people living with dementia in the U.S. and 57 million globally.
Nov 16, 2025
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How income may shape risk of dementia
People with lower incomes and people from racial and ethnic historically underrepresented groups in clinical studies are more likely to have modifiable risk factors for dementia, factors that could be changed to lower their ...
Nov 13, 2025
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Chemical compound holds potential against Alzheimer's disease
A team of researchers at the Federal University of ABC (UFABC) in Brazil has developed a new chemical compound with the potential to treat Alzheimer's disease. The research involved computer simulations (in silico), cell ...
Nov 12, 2025
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Alzheimer's risk calculator could spot danger years before symptoms begin
Mayo Clinic researchers have developed a new tool that can estimate a person's risk of developing memory and thinking problems associated with Alzheimer's disease years before symptoms appear.
Nov 12, 2025
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New oral treatment may prevent dementia
Researchers from DANDRITE have played a central role in developing a new oral treatment that, for the first time ever, has shown promising results in a clinical trial involving patients—a breakthrough that appears capable ...
Nov 12, 2025
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It's not just in your head: Stress may lead to altered blood flow in the brain
While the exact causes of neurodegenerative brain diseases like Alzheimer's and dementia are still largely unknown, researchers have been able to identify a key characteristic in affected brains: reduced blood flow. Building ...
Nov 11, 2025
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Following anti-amyloid therapy, MRI shows no short-term change in waste clearance function in Alzheimer's patients
A group from Osaka Metropolitan University in Japan, led by graduate student Tatsushi Oura and Dr. Hiroyuki Tatekawa, found that treatment using the drug lecanemab to remove amyloid plaques in the brain does not change the ...
Nov 11, 2025
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NAD⁺ restores memory in Alzheimer's disease models by correcting RNA errors
Alzheimer's disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments ...
Nov 10, 2025
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Zero-cost, AI-driven digital detection identifies Alzheimer's without additional clinician time
Few primary care practices are designed for the timely detection of Alzheimer's disease and related dementias. The limited time that primary care clinicians are able to spend with patients, the need to focus on the health ...
Nov 10, 2025
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Blood-platelet screening in midlife could identify early risk for Alzheimer's disease
A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer's disease decades ahead of time, allowing for possible preventive therapy.
Nov 10, 2025
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Review links air pollution and Alzheimer's and offers a preventive plan
A new peer-reviewed article published in the Journal of Alzheimer's Disease, by the Alzheimer's Research and Prevention Foundation, reveals compelling evidence that air pollution and climate stress are major (modifiable) ...
Nov 10, 2025
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New method to track progression of Alzheimer's, related dementias based on metabolic, vascular brain changes
Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes. They recently published their ...
Nov 10, 2025
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Just 3,000 steps a day linked to lower Alzheimer's risk in older adults
A new study suggests that even low levels of physical activity could protect the brain from Alzheimer's disease—but not in the way scientists expected.
Nov 9, 2025
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Why Alzheimer's patients forget loved ones
Few moments are more heartbreaking for families of Alzheimer's disease patients than when a loved one no longer recognizes them. New research from the University of Virginia School of Medicine published in Alzheimer's & Dementia ...
Nov 7, 2025
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New research finds dietary intervention of peanuts improves brain vascular function and memory
A study from the Institute of Nutrition and Translational Research in Metabolism (NUTRIM) at Maastricht University Medical Center, Maastricht, Netherlands, has found that the consumption of unsalted, skin-roasted peanuts ...
Nov 6, 2025
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Shared synaptic mechanism for Alzheimer's and Parkinson's disease unlocks new treatment possibilities
Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the Okinawa Institute of Science ...
Nov 5, 2025
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Protective microglia subtype offers potential therapeutic pathway in Alzheimer's disease
In Alzheimer's disease—the leading cause of dementia—microglia, the brain's immune defenders, can act as both protectors and aggressors, shaping how the disease progresses.
Nov 5, 2025
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Study finds heart health in midlife predicts dementia risk in older age
People with signs of damage to their heart during middle age are more likely to develop dementia in later life, according to a new study led by University College London researchers.
Nov 5, 2025
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