Brain biomarkers of Alzheimer's disease can be detected as early as middle age
A Finnish population study shows that signs related to Alzheimer's disease may already be found in the brain in middle age. In the future, blood-based biomarkers associated with Alzheimer's disease could allow earlier detection ...
Jul 14, 2025
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SARS-CoV-2 can cause buildup of Alzheimer's-related peptides in retina
A new Yale study has found a promising target for treating the brain fog that can follow COVID-19 and offers new insight into a hypothesis about the origin of Alzheimer's disease.
Jul 14, 2025
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Demystifying the link between major depression and Alzheimer's disease
More than 7 million people in the United States live with Alzheimer's disease and related dementia (ADRD). Some risk factors for ADRD, like genetics, can't be controlled, but others can be treated. One of the most prevalent ...
Jul 14, 2025
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Key brain protein may hold answers for memory loss and neurodegenerative diseases
Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for learning and memory.
Jul 11, 2025
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More misfolded proteins than previously known may contribute to Alzheimer's and dementia
For decades, the story of Alzheimer's research has been dominated by a battle between A-beta and tau amyloids, both of which can kill neurons and impact the brain's ability to function. A new study suggests, however, that ...
Jul 11, 2025
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CTE and normal aging are difficult to distinguish, new study finds
In recent years, some scientists and advocates have warned that playing contact sports like football and hockey may increase the risk of brain diseases like Alzheimer's disease or chronic traumatic encephalopathy (CTE) due ...
Jul 11, 2025
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Nerve pain drug gabapentin linked to increased dementia, cognitive impairment risks
Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and 85%, respectively—finds ...
Jul 10, 2025
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Study links COVID-19 and bacterial infection to Alzheimer's disease
A recent review by researchers at Philadelphia College of Osteopathic Medicine (PCOM) shows Chlamydia pneumoniae (Cpn) and SARS-CoV-2 infections may play a role in the pathogenesis of Alzheimer's disease.
Jul 10, 2025
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Q&A: Team discusses uncovering ApoE3 Christchurch's multi-pathway defense against Alzheimer's
Researchers have published a paper in Alzheimer's & Dementia, titled "ApoE3 Christchurch and tau interaction as a protective mechanism against Alzheimer's disease."
Jul 10, 2025
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A 'Google Maps' for tau movement sheds light on why some brain regions resist Alzheimer's
It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau—a protein known to misbehave—plays an important role in the disease. Normally, tau helps stabilize neurons, but ...
Jul 9, 2025
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Novel AI method sheds light on how enzyme linked to Alzheimer's selects its targets
Researchers from DZNE, Ludwig-Maximilians-Universität München (LMU), and Technical University of Munich (TUM) have found that the enzyme "gamma-secretase"—implicated in Alzheimer's disease and cancer—selects its reaction ...
Jul 9, 2025
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Why are women twice as likely to develop Alzheimer's as men?
A neglected piece of the Alzheimer's puzzle has been getting increased scientific attention: why women are twice as likely as men to develop the disease.
Jul 8, 2025
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People diagnosed with dementia are living longer, global study shows
A person diagnosed with dementia has improved survival outcomes in recent years amid significant progress in dementia diagnosis and care, according to a recent multinational study led by a University of Waterloo researcher.
Jul 8, 2025
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ADAM10 protein levels in blood linked to early Alzheimer's and genetic risk factors
Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, are developing a panel of biomarkers for the early detection of Alzheimer's disease and for distinguishing it from other types ...
Jul 8, 2025
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Dementia protection linked to where the body lies—belly fat a risk factor
Men with high levels of belly fat are at increased risk of dementia, according to a new study by Monash University researchers of more than 17,000 individuals aged 65 to 98 years in the ASPREE Study.
Jul 8, 2025
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Elderly people with dementia being subjected to violence, abuse and neglect in their own homes
There's a clear downside to the Norwegian policy that encourages allowing elderly people to live at home for as long as possible. Caring for the aging population has been left to worn-out family members.
Jul 8, 2025
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New study maps four key pathways to Alzheimer's disease
UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated ...
Jul 7, 2025
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New blood biomarker predicts progression of Alzheimer's disease even in its earliest stages
A team of researchers at the Sant Pau Research Institute (IR Sant Pau) has demonstrated that the plasma biomarker p-tau217, obtained through a simple blood test, can predict the clinical progression of Alzheimer's disease ...
Jul 7, 2025
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Death of a partner and financial stress linked to increased risk of Alzheimer's disease, differences in brain structure
Stressful life events can negatively impact brain health. Specifically, grief over the loss of a partner has been linked to alterations in biological processes associated with Alzheimer's disease, while unemployment and financial ...
Jul 3, 2025
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First large-scale stem cell bank enables worldwide studies on genetic risk for Alzheimer's disease
Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10% of people over the age of 65 and one third of people aged 85 and above. Besides environmental factors, the genes have a strong ...
Jul 3, 2025
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Blood stem cell mutations linked to lower risk of late-onset Alzheimer's disease
A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset Alzheimer's disease.
Jul 2, 2025
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Resilience and perceived gains can shape mental health in dementia caregivers
University of Tennessee assistant professor Dr. Fei Wang's latest research, published in Research on Aging, uncovers how resilience plays a key role in shaping mental health outcomes among U.S. caregivers—especially distinguishing ...
Jul 1, 2025
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Discovery of key brain repair mechanism in vascular dementia reveals promising therapeutic target
A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional ...
Jun 30, 2025
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