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Alzheimer's disease & dementia news

Alzheimer's disease & dementia

A shared five biomarker profile across four major neurodegenerative diseases

The Global Neurodegeneration Proteomics Consortium (GNPC) has published a series of research papers detailing their efforts to identify patterns in neurodegenerative disease. Sifting through roughly 250 million plasma measurements, ...

Neuroscience

Dietary intervention optimized using machine learning could lower risk of dementia

The term dementia is used to describe various debilitating neurological disorders characterized by a progressive loss of memory and a decline in mental abilities. Estimates suggest that over 55 million people worldwide are ...

Alzheimer's disease & dementia

People diagnosed with dementia are living longer, global study shows

A person diagnosed with dementia has improved survival outcomes in recent years amid significant progress in dementia diagnosis and care, according to a recent multinational study led by a University of Waterloo researcher.

Psychology & Psychiatry

New study maps four key pathways to Alzheimer's disease

UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated ...

Genetics

Newly found genetic variant defends against Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease. The study, "Rare ...

Alzheimer's disease & dementia

Human neuron model paves the way for new Alzheimer's therapies

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer's disease ...

Neuroscience

Untangling the threads of early onset dementia

Changes in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementia in patients under the age of 65, which is associated with degeneration of the frontal and temporal ...

Alzheimer's disease & dementia

Immunotherapy for Alzheimer's disease shows promise in mouse study

Alzheimer's disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline. The new generation of Alzheimer's ...

Neuroscience

New imaging method illuminates oxygen's journey in the brain

The human brain consumes vast amounts of energy, which is almost exclusively generated from a form of metabolism that requires oxygen. While the efficient and timely delivery of oxygen is known to be critical to healthy brain ...

Alzheimer's disease & dementia

Unlocking how to use mRNA to target Alzheimer's disease

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

Alzheimer's disease & dementia

Patients with delirium more likely to develop dementia, finds study

University of Queensland researchers have found older patients who experience delirium are three times more likely to develop dementia. Professor Ruth Hubbard from UQ's Center for Health Services Research (CHSR) said the ...