Alzheimer's disease & dementia

Midlife changes in Alzheimer's biomarkers may predict dementia

Studying brain scans and cerebrospinal fluid of healthy adults, scientists have shown that changes in key biomarkers of Alzheimer's disease during midlife may help identify those who will develop dementia years later, according ...

Alzheimer's disease & dementia

Study shows where Alzheimer's starts and how it spreads

Using high-resolution functional MRI (fMRI) imaging in patients with Alzheimer's disease and in mouse models of the disease, Columbia University Medical Center (CUMC) researchers have clarified three fundamental issues about ...

Alzheimer's disease & dementia

Rare gene variants double risk for Alzheimer's disease

A team led by researchers at Washington University School of Medicine in St. Louis has identified variations in a gene that doubles a person's risk of developing Alzheimer's disease later in life.

Alzheimer's disease & dementia

11 new genetic susceptibility factors for Alzheimer's disease discovered

The largest international study ever conducted on Alzheimer's disease (AD), the I-GAP (International Genomics Alzheimer's Project) consortium has identified 11 new regions of the genome involved in the onset of this neurodegenerative ...

Alzheimer's disease & dementia

New drug reverses loss of brain connections in Alzheimer's disease

The first experimental drug to boost brain synapses lost in Alzheimer's disease has been developed by researchers at Sanford-Burnham Medical Research Institute. The drug, called NitroMemantine, combines two FDA-approved medicines ...

Alzheimer's disease & dementia

Scientists identify molecular trigger for Alzheimer's disease

Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons in the brain.

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