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Arthritis & Rheumatism news

Diseases, Conditions, Syndromes

Fine particles in pollution are associated with early signs of autoimmune disease

A new study has linked air pollution exposure and immune-system changes that often precede the onset of autoimmune diseases.

Arthritis & Rheumatism

Study uncovers beneficial relationship between gardening and osteoarthritis

Gardening/yardwork is one of the few forms of leisure physical activity that people tend to do more as they age. Osteoarthritis is the most common form of arthritis and a major cause of disability that also tends to occur ...

Arthritis & Rheumatism

New clinical guidelines address gap in Adult-onset Still's disease

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder. Thanks to a new initiative, AOSD is now considered to be the adult counterpart of systemic juvenile idiopathic arthritis, but in both cases the cause is ...

Arthritis & Rheumatism

Why certain arthritis drugs don't work in rheumatoid arthritis

Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...

Arthritis & Rheumatism

Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Arthritis & Rheumatism

New points to consider in treatment-resistant psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

Arthritis & Rheumatism

Why so many pro soccer players develop osteoarthritis

A new paper finds that retired UK male professional soccer players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement. Retired players treated routinely with ...

Arthritis & Rheumatism

SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...

Arthritis & Rheumatism

Arthritis pain rising: How state policies matter

New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.

Genetics

Gene linked to rheumatic disease controls cell movement

A team of researchers at Karolinska Institutet, together with colleagues from Linköping University, has uncovered the function of a gene called DIORA1 (FAM167A), previously linked to autoimmune rheumatic diseases such as ...

Arthritis & Rheumatism

Causes of osteoarthritis mapped in new biobank

Through molecular studies of knee tissue and advanced synchrotron radiation imaging techniques, researchers hope to gain new insights into the early development of osteoarthritis. The hope is to pave the way for new treatments.

Arthritis & Rheumatism

Prevalence of arthritis 305 per 100,000 children, teens in U.S.

The prevalence of arthritis is 305 per 100,000 children and adolescents in the United States, with higher prevalence among non-Hispanic Black or African American versus non-Hispanic White children and adolescents, according ...

Arthritis & Rheumatism

Treatment effect of tofacitinib, adalimumab compared in RA

For adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients receiving tofacitinib (TOF) versus adalimumab ...

Arthritis & Rheumatism

JAK signaling may be behind polymyalgia rheumatica

Janus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study published online June 29 in PLOS Medicine.

Arthritis & Rheumatism

How chronic knee osteoarthritis pain affects cognitive function

New research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other factors like age, pain medication and socio-economic factors are likely to play ...

Arthritis & Rheumatism

Q and A: Spinal arthritis

I am in my late 50s and have started having stiffness in my back. I have become much less flexible and sometimes even have a hard time looking over my shoulder. I remember my grandparents complaining about arthritis in their ...

Health

Researchers unlock predictive biomarkers for common hip disorder

Researchers from the University of Missouri School of Medicine have developed panels of protein biomarkers present in teens and young adults that distinguish individuals with healthy hips from those with developmental dysplasia ...

Medical research

New therapeutic target for osteoarthritis identified

Investigators have discovered that a subset of sensory neurons promote osteoarthritis-related joint pain and inflammation, suggesting a new therapeutic target for pain management, according to findings published in Nature ...