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Arthritis & Rheumatism news

Diseases, Conditions, Syndromes

Fine particles in pollution are associated with early signs of autoimmune disease

A new study has linked air pollution exposure and immune-system changes that often precede the onset of autoimmune diseases.

Arthritis & Rheumatism

Study uncovers beneficial relationship between gardening and osteoarthritis

Gardening/yardwork is one of the few forms of leisure physical activity that people tend to do more as they age. Osteoarthritis is the most common form of arthritis and a major cause of disability that also tends to occur ...

Arthritis & Rheumatism

New clinical guidelines address gap in Adult-onset Still's disease

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder. Thanks to a new initiative, AOSD is now considered to be the adult counterpart of systemic juvenile idiopathic arthritis, but in both cases the cause is ...

Arthritis & Rheumatism

Why certain arthritis drugs don't work in rheumatoid arthritis

Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...

Arthritis & Rheumatism

Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Arthritis & Rheumatism

New points to consider in treatment-resistant psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

Arthritis & Rheumatism

Why so many pro soccer players develop osteoarthritis

A new paper finds that retired UK male professional soccer players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement. Retired players treated routinely with ...

Arthritis & Rheumatism

Arthritis pain rising: How state policies matter

New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.

Arthritis & Rheumatism

SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...

Genetics

Gene linked to rheumatic disease controls cell movement

A team of researchers at Karolinska Institutet, together with colleagues from Linköping University, has uncovered the function of a gene called DIORA1 (FAM167A), previously linked to autoimmune rheumatic diseases such as ...

Arthritis & Rheumatism

Obesity lowering the age for knee replacements

More than half of Australians who underwent knee replacement for osteoarthritis were obese, increasing their risk of having the operation at a younger age, especially among women.

Medical research

UHRF1 suppresses pathogeneses in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterized by chronic inflammation of synovium, eventually leading to joint destruction. Epigenetic alteration (the mechanism of gene expression regulation without DNA sequence changes), such ...

Arthritis & Rheumatism

The importance of treatment goals in PSA

PsA is a type of inflammatory arthritis linked to psoriasis—a chronic condition affecting the skin and nails. People with PsA experience pain and swelling in their joints, and at the points where tendons and ligaments attach ...

Arthritis & Rheumatism

Patient involvement and empowerment: Coping with rheumatic diseases

At the 2022 EULAR Congress, Joana Vicente presented the findings of a survey which set out to identify the levels of invalidation and lack of understanding felt by adults with RMDs from health professionals and other people. ...

Arthritis & Rheumatism

Investigating the link between a type of antibody and miscarriage

Miscarriage affects an estimated 15% of pregnancies, but in about half of cases the cause is unclear. At Yale, reproductive immunologist Vikki Abrahams and reproductive biologist Mancy Tong are interested in shining a light ...

Arthritis & Rheumatism

Treating knee osteoarthritis without surgery

Dr. Prakash Jayabalan has long pondered why more non-operative treatment options aren't available to patients with knee osteoarthritis (OA), particularly because it is the most common cause of disability in the U.S.