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Arthritis & Rheumatism news

Diseases, Conditions, Syndromes

Fine particles in pollution are associated with early signs of autoimmune disease

A new study has linked air pollution exposure and immune-system changes that often precede the onset of autoimmune diseases.

Arthritis & Rheumatism

Study uncovers beneficial relationship between gardening and osteoarthritis

Gardening/yardwork is one of the few forms of leisure physical activity that people tend to do more as they age. Osteoarthritis is the most common form of arthritis and a major cause of disability that also tends to occur ...

Arthritis & Rheumatism

New clinical guidelines address gap in Adult-onset Still's disease

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder. Thanks to a new initiative, AOSD is now considered to be the adult counterpart of systemic juvenile idiopathic arthritis, but in both cases the cause is ...

Arthritis & Rheumatism

Why certain arthritis drugs don't work in rheumatoid arthritis

Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...

Arthritis & Rheumatism

Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Arthritis & Rheumatism

New points to consider in treatment-resistant psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

Arthritis & Rheumatism

Why so many pro soccer players develop osteoarthritis

A new paper finds that retired UK male professional soccer players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement. Retired players treated routinely with ...

Arthritis & Rheumatism

Arthritis pain rising: How state policies matter

New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.

Arthritis & Rheumatism

SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...

Genetics

Gene linked to rheumatic disease controls cell movement

A team of researchers at Karolinska Institutet, together with colleagues from Linköping University, has uncovered the function of a gene called DIORA1 (FAM167A), previously linked to autoimmune rheumatic diseases such as ...

Genetics

Eleven novel loci identified for rheumatoid arthritis

Eleven novel loci and 90 independent association signals have been identified for rheumatoid arthritis (RA), according to a study published in the May issue of the Annals of the Rheumatic Diseases.

Arthritis & Rheumatism

Physical activity reduces cardiovascular risk in rheumatic patients

The risk of developing atherosclerosis—a narrowing of the arteries as cholesterol plaque builds up, leading to obstruction of blood flow—is higher for people with autoimmune rheumatic diseases than for the general population. ...

Arthritis & Rheumatism

Early-life exposure to famine linked to increased odds of RA

(HealthDay)—Individuals exposed to famine in utero or in early childhood have an increased likelihood of developing rheumatoid arthritis (RA) in adulthood, according to a study published in the April issue of Arthritis ...

Arthritis & Rheumatism

New insights on inflammation in COVID-19

Severe cases of COVID-19 can involve extensive inflammation in the body, and clinicians have wondered if this state is similar to what are called cytokine storm syndromes, in which the immune system produces too many inflammatory ...

Health

Dust at work can lead to rheumatic diseases

If you are exposed to silica (quartz) dust at work—e.g. from working with concrete and granite—you have a greater risk of certain types of rheumatic disease. This is shown by results from Aarhus University and Aarhus ...

Health

Program may help patients with rheumatic diseases quit smoking

Smoking increases symptoms and health risks for patients with rheumatic diseases, but interventions to help patients quit are rarely available at rheumatology clinics. A study published in Arthritis Care & Research has found ...

Medications

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of the New England Journal of Medicine.

Arthritis & Rheumatism

Helping childhood-onset lupus patients stay healthy as adults

UT Southwestern researchers have identified factors that put patients with childhood-onset lupus at elevated risk for poor outcomes, such as end-stage renal disease or death, as they transition from pediatric to adult health ...

Cardiology

CVD risk factors tied to disease activity, disability in RA

(HealthDay)—Cardiovascular disease (CVD) risk factors alone, or in combination, are associated with higher disease activity and disability in rheumatoid arthritis (RA), according to a study recently published in Therapeutic ...

Arthritis & Rheumatism

Researchers reveal UK trends in inflammatory eye disease

Scleritis is a vision-threatening inflammatory condition of the white portion of the eye, or the sclera, that is thought to be the result of an over-reaction of the body's immune system. A new study published in Arthritis ...