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Arthritis & Rheumatism news

Diseases, Conditions, Syndromes

Fine particles in pollution are associated with early signs of autoimmune disease

A new study has linked air pollution exposure and immune-system changes that often precede the onset of autoimmune diseases.

Arthritis & Rheumatism

Study uncovers beneficial relationship between gardening and osteoarthritis

Gardening/yardwork is one of the few forms of leisure physical activity that people tend to do more as they age. Osteoarthritis is the most common form of arthritis and a major cause of disability that also tends to occur ...

Arthritis & Rheumatism

New clinical guidelines address gap in Adult-onset Still's disease

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder. Thanks to a new initiative, AOSD is now considered to be the adult counterpart of systemic juvenile idiopathic arthritis, but in both cases the cause is ...

Arthritis & Rheumatism

Why certain arthritis drugs don't work in rheumatoid arthritis

Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...

Arthritis & Rheumatism

Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Arthritis & Rheumatism

New points to consider in treatment-resistant psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

Arthritis & Rheumatism

Why so many pro soccer players develop osteoarthritis

A new paper finds that retired UK male professional soccer players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement. Retired players treated routinely with ...

Arthritis & Rheumatism

SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...

Arthritis & Rheumatism

Arthritis pain rising: How state policies matter

New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.

Genetics

Gene linked to rheumatic disease controls cell movement

A team of researchers at Karolinska Institutet, together with colleagues from Linköping University, has uncovered the function of a gene called DIORA1 (FAM167A), previously linked to autoimmune rheumatic diseases such as ...

Arthritis & Rheumatism

Link found between kneecap shape and debilitating joint disease

The shape of a person's kneecap could be an indicator of whether they're more at risk of developing osteoarthritis, according to a new study from The Australian National University (ANU) published in Osteoarthritis and Cartilage.

Arthritis & Rheumatism

Air pollution may affect lupus risk

New research published in Arthritis & Rheumatology indicates that chronic exposure to air pollutants may increase the risk of developing lupus, an autoimmune disease that affects multiple organs.

Arthritis & Rheumatism

World's first CAR-T cell therapy for a child with lupus

In June 2023, Uresa A. (who was 15 years old at the time) received CAR-T cells at Universitätsklinikum Erlangen. The treatment was the last resort to slow down systemic lupus erythematosus (SLE), which is a serious autoimmune ...

Arthritis & Rheumatism

FDA expands pediatric indication for Rinvoq

The U.S. Food and Drug Administration has expanded indications for AbbVie's Rinvoq (upadacitinib) to now include pediatric patients (ages 2 years and older) with polyarticular juvenile idiopathic arthritis (pJIA) and psoriatic ...

Arthritis & Rheumatism

The impact of lifestyle intervention in rheumatoid arthritis

EULAR—The European Alliance of Associations for Rheumatology—has previously made recommendations for lifestyle interventions in people with rheumatic and musculoskeletal diseases, including rheumatoid arthritis (RA). ...

Diseases, Conditions, Syndromes

New insights into the role of salivary glands in Sjögren's disease

Sjögren's disease primarily affects the salivary and lacrimal glands, resulting in tissue inflammation characterized by the formation of tertiary lymphoid structures (TLS), and a loss of glandular function—resulting in ...

Arthritis & Rheumatism

Is fish intake linked to juvenile idiopathic arthritis?

Juvenile idiopathic arthritis (JIA) results from a complex interplay of genetic and environmental factors. Past efforts to identify JIA's environmental risk factors have been restricted due to limited high-quality data and ...

Diseases, Conditions, Syndromes

Investigating novel treatment options in systemic sclerosis

EULAR, The European Alliance of Associations for Rheumatology, updated its recommendations for systemic sclerosis (SSc) in 2023. Notably, four new therapies were added that had not been included in 2017—highlighting how ...

Arthritis & Rheumatism

Tackling issues in childhood arthritis

Rheumatological diseases can affect people during childhood, the most common being juvenile idiopathic arthritis (JIA). As well as a need to generally raise awareness of childhood arthritis, there is also a crucial need to ...

Arthritis & Rheumatism

Encouraging cooperation in inflammatory arthritis

There is a need to improve cross-sectoral care for people with inflammatory arthritis. The Danish Centre for Expertise in Rheumatology (CeViG) at the Danish Hospital for Rheumatic Diseases in Sønderborg, Denmark, is a unique ...

Diseases, Conditions, Syndromes

Unpicking the complexity of systemic sclerosis

In 2023, The European Alliance of Associations for Rheumatology(EULAR) updated its recommendations for the treatment of systemic sclerosis (SSc), with many new inclusions around manifestations such as skin fibrosis and interstitial ...