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Laboratory medicine news
A 19-protein blood panel can predict when ALS symptoms will emerge
Months to several years before amyotrophic lateral sclerosis (ALS) symptoms arise, levels of certain blood proteins may shift dramatically. Researchers analyzed data from the long-running Pre-symptomatic Familial ALS (Pre-fALS) ...
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Brain cancer map uncovers thousands of hidden targets for personalized immunotherapies
Researchers from the Clinical Neuroscience Consortium (CNC), a collaborative platform jointly established by the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and Queen Mary Hospital, in collaboration with ...
Jul 23, 2026
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Gene activity in blood fluctuates more than expected—and that has consequences for medicine
Take a blood sample from someone in the dead of winter. Take another in midsummer. Same person, same laboratory. And yet, at the level of gene activity, the molecular picture can look surprisingly different. This is not an ...
Jul 23, 2026
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From urinary tract infection to brain abscess: How bacterial subpopulations can spread to distant body sites
Researchers from the University of Cologne, the German Center for Infection Research (DZIF), and the Broad Institute of Harvard and MIT present a clinical case in the New England Journal of Medicine that provides new insights ...
Jul 23, 2026
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RNA testing uncovers 171 mutations driving MET exon 14 skipping in lung cancer
New research has shown that RNA-based testing can improve the detection and interpretation of clinically actionable genomic alterations that lead to MET exon 14 skipping in patients with lung cancer—important biomarkers that ...
Jul 23, 2026
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A single blood sample may improve the prediction of colorectal cancer recurrence or metastasis
A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer. A joint research team from KAIST, Gangnam Severance Hospital and Asan Medical Center has shown ...
Jul 22, 2026
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Paradigm shift in oncology: The emergence of point-of-care diagnostic technology
Who doesn't want cancer testing results at lower cost, with greater speed and accuracy? Interdisciplinary innovators like Cancer Center at Illinois (CCIL) program leader Brian Cunningham are among the pioneers of the emerging ...
Jul 21, 2026
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Biological sex linked to protein changes in lung adenocarcinoma and other cancers
Biological sex factors into cancer in ways you might not expect. In lung cancer, a form called squamous cell carcinoma disproportionately affects male patients, while adenocarcinoma occurs more frequently in female patients. ...
Jul 21, 2026
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Mapping human bone marrow yields new tool, insights on blood cancer
Weill Cornell Medicine investigators have developed a new AI-based method to assess patients with a form of blood cancer called myelodysplastic neoplasms. The method, published June 30 in Leukemia, compares the physical locations ...
Jul 20, 2026
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DNA blood test improves patient selection for radiopharmaceutical therapy in prostate cancer
A noninvasive DNA blood test can identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are most likely to benefit from 223Ra radiopharmaceutical therapy and monitor their progress throughout treatment, ...
Jul 20, 2026
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New topology-based biomarkers may improve breast cancer prediction
For decades, pathologists have diagnosed and graded breast cancer by looking at tissue samples under a microscope, searching for telltale signs of disorder in the structure of cells and tissues. Now, researchers at Columbia ...
Jul 19, 2026
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Warm nights linked to ill premature babies in NICUs
Premature babies in the intensive care unit are particularly at risk of becoming infected with potentially pathogenic bacteria. A team of doctors in Hanover has now investigated which external factors play a role in this. ...
Jul 18, 2026
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Disrupted antioxidant balance linked to the development of 'Skellefteå disease'
Researchers at Umeå University have identified changes in the body's major antioxidant systems in patients with hereditary transthyretin (TTR) amyloidosis. The findings support the hypothesis that oxidative stress contributes ...
Jul 16, 2026
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Blood-based test can predict risk of developing symptoms of Alzheimer's up to a decade early
A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged about the extent to which such tests can accurately predict whether a cognitively healthy individual ...
Jul 15, 2026
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Study shows a blood test can help identify healthy people at high risk for Alzheimer's disease
A blood test may predict if apparently healthy older adults are likely to develop Alzheimer's symptoms in the next five or 10 years, researchers reported Wednesday.
Jul 15, 2026
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New machine-learning equation accurately assess LDL cholesterol risk
The Martin-Hopkins equation to assess low-density lipoprotein (LDL) cholesterol levels in blood samples has been used by laboratories in the U.S. and other countries to guide efforts to lower cardiovascular disease risk. ...
Jul 15, 2026
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Molecular map of liver disease could transform how disease is diagnosed and monitored
A study led by researchers at Open Targets, EMBL's European Bioinformatics Institute (EMBL-EBI), the University of Cambridge and others has identified a set of plasma proteins that could be used to diagnose and monitor patients ...
Jul 15, 2026
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Researchers upgrade allergy test to better detect the antibodies that trigger reactions
Allergies can be minor or life-threatening, and current diagnostic blood tests are not always adequate for determining which substances patients need to avoid to prevent a reaction.
Jul 15, 2026
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Sound waves guide cultured cells to form vessel-like networks within one week
With the aid of physical forces—in this case, sound—it is possible to actively steer the formation of engineered tissue. For example, sound waves can be used to create functional vascular networks with blood vessel-like structures ...
Jul 14, 2026
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Gold nanoparticle sensor measures early liver fibrosis marker from small blood samples
A research team led by Professor Jinsung Park of the Department of Biomechatronic Engineering at Sungkyunkwan University (SKKU), working jointly with Professor Pil-Soo Sung of the College of Medicine at the Catholic University ...
Jul 14, 2026
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Raman imaging applied to cardiac tissue of Fabry disease model reveals molecular map of lipids in tissue
How are disease-relevant molecules distributed within tissue? What changes occur even before they become visible under the microscope? Questions such as these are crucial for early diagnosis and targeted treatment in many ...
Jul 13, 2026
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Hepatitis E viruses mutate early during infection
Knowing how viruses change in the initial weeks of an infection can provide important information about their adaptability. Researchers from the Departments of Molecular & Medical Virology and Translational & Computational ...
Jul 13, 2026
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Body's own cell-to-cell messaging packets studied as the basis for next-generation medicines
The Blood and Tissue Bank is studying how to therapeutically manufacture and use a type of nanoparticles released by the body's cells to communicate with one another, in one of the most promising fields of research for the ...
Jul 12, 2026
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Bacterial responses to plasma may forecast mild vs severe COVID-19
Information processing using living organisms is an important area of biotechnology that has already been explored in previous studies.
Jul 11, 2026
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Epigenetic mapping provides deeper insight into leukemia
Researchers at Karolinska Institutet in Sweden and Kyoto University in Japan have identified new subgroups of the blood cancer acute myeloid leukemia. The study, published in the journal Nature, shows that changes in the ...
Jul 9, 2026
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