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Laboratory medicine news

Human red blood cells form without central 'hub' seen in mouse models, upending understanding of our physiology

Northwestern Medicine scientists have discovered that one of the body's most fundamental biological processes—how red blood cells are made—works differently in humans than previously thought, according to a new study published ...

Novel biomarker beats leading diagnostic blood test at predicting Alzheimer's progression

Small loops of genetic material may be strong indicators of imminent Alzheimer's disease (AD) symptoms. In a new study published in Nature Medicine, researchers showed that elevated levels of certain circular RNAs (circRNAs) ...

Blood test finds hidden pancreatic cancer after treatment

Northwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more ...

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...

CT tissue images can now be virtually stained in 3D

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, ...

Therapeutic target for dangerous fungal infections identified

A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide ...