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Laboratory medicine news

Hidden skin microbe activity revealed in real time with RNA method

Scientists have long known that our skin is home to vast communities of bacteria, fungi and viruses. But knowing which microbes are present only tells part of the story. What matters just as much is which microbes are active, ...

Without the right tests, the best medicines make no difference

A new analysis from UC San Francisco argues that diagnostics—medical tests that match patients to the appropriate treatment—are being overlooked both in the United States and around the world. This is slowing progress against ...

A better way to see how brain cells falter in disease

To gain better insight into what's happening in the brain, researchers examine the molecules produced by brain cells, including RNA and proteins. But existing methods for molecular profiling don't always capture the cells' ...

New test identifies active, infectious form of tuberculosis

Researchers in the UC Davis Department of Pathology and Laboratory Medicine have created a new tuberculosis blood test that can detect the active, infectious form of the disease. The discovery enables faster diagnosis and ...

Bile acid and steroid signatures tied to extreme longevity

Centenarians often live to 100+ due to a combination of protective genetic factors, which account for up to 50%, and healthy lifestyles, such as plant-forward diets, regular, natural movement and strong social connections. ...

New biomarker for immunoglobulin A nephropathy identified

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced ...

How gene-targeting technology is transforming STI diagnosis

Most people who have heard of clustered regularly interspaced short palindromic repeats (more commonly known as CRISPR) associate it with gene editing—the precise molecular scissors that allow scientists to cut and rewrite ...