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Laboratory medicine news

Faster aging, chronic disease linked to WTC responders with PTSD

Post-traumatic stress disorder (PTSD) remains a common condition affecting World Trade Center (WTC) responders 25 years after the attack on the Twin Towers. While the condition is considered mainly psychological, a new study ...

GenAI overcomes slide misalignment to produce virtual stains close to real slides

Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples.

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...

CT tissue images can now be virtually stained in 3D

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, ...

Therapeutic target for dangerous fungal infections identified

A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide ...

AI diagnoses brain tumors in minutes instead of weeks

Experts in Heidelberg, Germany, have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more ...

Blood test reveals risk of multimorbidity in older adults

A small set of common blood biomarkers predicts which older adults will develop specific combinations of chronic diseases—and how quickly, according to a new study from Karolinska Institutet published in Nature Medicine.

Costs pose hurdle for promising new hepatitis C lab test

A new rapid test for hepatitis C could help identify many more patients who could be cured of the deadly disease, but its use may be limited unless insurers' reimbursement rises to cover its high cost, according to researchers ...

New ALS diagnostic blood test boasts 97% accuracy

ALS is a debilitating paralytic disease characterized as the death of upper and lower motor neurons. Fortunately, ALS is relatively rare, with an incidence rate of 1.6 per 100,000 adults, resulting in about 30,000 cases in ...

Your blood proteins could predict your risk of an early death

Imagine if a simple blood test could offer a glimpse into your future health. Not just whether you have heart disease or cancer today, but whether your overall risk of dying in the next five or ten years is higher or lower ...

Cell-free DNA could detect adverse events from immunotherapy

A noninvasive blood test to detect genetic material shed by tumors may help clinicians identify adverse events related to treatment with immune checkpoint inhibitor drugs, investigators at the Johns Hopkins Kimmel Cancer ...