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Laboratory medicine news
I teach doctors how to interpret test results—and the labels 'normal' and 'abnormal' often hide what matters most
V felt tightness across his chest. His deepest breaths felt shallow. He sought help at an emergency department, where a resident physician found several worrying signs, including swelling of his hands and legs as well as ...
40 minutes ago
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Blood proteins may offer new clues to gut health in celiac disease
Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.
20 hours ago
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Most labs testing children for cardiac troponin lack pediatric reference ranges, survey finds
Cardiac troponin, a protein released into the blood when heart muscle is damaged, can be used as a quick measure of heart injury in adults, and testing for it has revolutionized adult cardiology. For children, however, doctors ...
Oct 10, 2026
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A new AI tool distinguishes Ewing sarcoma from similar tumors
A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated an artificial intelligence (AI) system capable of distinguishing Ewing sarcoma from other morphologically ...
Oct 8, 2026
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FDA-cleared urine test delivers results for invasive aspergillosis within hours
Through long-standing research supported by the National Institutes of Health, investigators at Johns Hopkins Medicine have advanced understanding of ways to better detect invasive aspergillosis (IA). Caused by mold, the ...
Oct 8, 2026
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Serum C7 levels predict liver-related events in metabolic fatty liver disease, study finds
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major cause of liver-related morbidity and mortality worldwide. As the disease progresses, liver fibrosis and liver-related events (LREs), including hepatocellular ...
Oct 8, 2026
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NHS labs fail to share data vital for diagnosis and care of rare diseases, investigation finds
Three of England's seven NHS genetics laboratories are failing to routinely share vital information about genetic variants in public databases that helps patients with rare diseases access diagnosis and care, an investigation ...
Oct 7, 2026
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Faster, more accurate newborn sepsis test in development
Testing newborn babies for sepsis could become faster and more accurate, reducing complications and deaths, thanks to the development of a Western Australia–led point-of-care neonatal sepsis test.
Oct 7, 2026
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Rapid low-cost diagnosis within reach for tuberculosis 'missed millions,' researchers find
These findings were generated by the largest-ever study of "pooled" tuberculosis (TB) testing, carried out by Start4All, a partnership led by LSTM with the Stop TB Partnership and research partners in seven countries with ...
Oct 7, 2026
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Do you really need to fast before every blood test? New study suggests not
Even a routine blood test may come with an overnight fasting requirement. Many medical practices still ask patients to go without food for 8–12 hours before blood is drawn. While the protocol was originally recommended for ...
International study validates less invasive approach to diagnosing mitochondrial disease
Researchers at Children's Hospital Colorado (Children's Colorado) and the University of Colorado Anschutz School of Medicine have published one of the largest studies to date evaluating advanced laboratory testing for mitochondrial ...
Oct 6, 2026
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Poor antibody validation wastes millions of biological samples, but solutions exist
A widespread failure to validate research antibodies before use is estimated to lead to the avoidable waste of millions of animal and human tissue samples worldwide, and an international expert panel has reached consensus ...
Oct 6, 2026
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Sickle cell pain may involve previously unrecognized biological pathways
A small pilot study led by a Rutgers researcher has found differences in blood proteins between people experiencing high and low levels of pain from sickle cell disease, findings that may inform research on new treatments ...
Oct 6, 2026
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DNA sequencing identifies fungal bloodstream infections before cultures turn positive
Bloodstream infections are a persistent threat to hospitalized patients, and those caused by fungi are particularly dangerous. Candida species are responsible for most invasive fungal infections worldwide and rank among the ...
Oct 5, 2026
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Candy-coated Lollylab checks saliva for medication
What if checking medication levels were as simple as enjoying a lollipop? A candy-coated device called Lollylab could provide the answer. In ACS Sensors, researchers describe how the lollipop's stem transfers saliva to a ...
Oct 5, 2026
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RNA urine test outperforms standard bladder cancer tests and could help guide treatment
A simple urine test devised by researchers at Stanford Medicine and the VA Palo Alto Health Care System can diagnose bladder cancer more accurately than current standard methods. The test also allows physicians not only to ...
Oct 2, 2026
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Mass spectrometry offers faster look at the edges of brain tumors
Glioma brain tumors are diffuse, so surgeons usually cannot excise all of the cancer during surgery. Currently, surgeons remove as much of the tumor as they can and then analyze the tumor's borders after surgery.
Oct 2, 2026
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Chemistry professors' patent detects amino acid linked to M.S., rheumatoid arthritis, cancer
More than a decade of work by two University of Wisconsin-Stout Polytechnic faculty members and their student researchers has led to a newly patented process that allows for the easy detection of an amino acid linked to multiple ...
Oct 1, 2026
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Possible new target for sickle cell disease and beta thalassemia treatment identified
Harvard Medical School researchers at Boston Children's Hospital and Dana-Farber Cancer Institute have identified a new pathway that regulates the production of fetal hemoglobin, a form of hemoglobin that normally gets replaced ...
Sep 30, 2026
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Detecting diseases through body odor? New laser technology shows potential for non-invasive diagnostics
Researchers at the Fraunhofer Institute for Integrated Circuits IIS and the Technical University of Dresden have tested a new approach for investigating disease-related changes in body odor. Using laser-based photoacoustic ...
Sep 29, 2026
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Low-cost platform maps gene activity and metabolites in the same tissue sample
Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within ...
Sep 29, 2026
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New genetic testing guidance could improve patient diagnosis worldwide
New guidance co-led by University of Otago researchers could help more people with suspected inherited diseases receive a clear genetic diagnosis.
Sep 29, 2026
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Global survey reveals major variation in the measurement of bone and mineral metabolism biomarkers
Researchers from the International Osteoporosis Foundation (IOF) and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Joint Committee on Bone Metabolism published a study examining self-reported ...
Sep 29, 2026
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Bedside blood test can deliver results in under 10 minutes to guide urgent stroke care
Minutes count when a patient with a stroke arrives at a hospital emergency room. Doctors stand ready to treat the patient, but whether medication can dissolve the blood clot depends on what the patient is already taking. ...
Sep 28, 2026
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