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Laboratory medicine news

Faster aging, chronic disease linked to WTC responders with PTSD

Post-traumatic stress disorder (PTSD) remains a common condition affecting World Trade Center (WTC) responders 25 years after the attack on the Twin Towers. While the condition is considered mainly psychological, a new study ...

GenAI overcomes slide misalignment to produce virtual stains close to real slides

Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples.

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...

CT tissue images can now be virtually stained in 3D

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, ...

Therapeutic target for dangerous fungal infections identified

A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide ...

AI diagnoses brain tumors in minutes instead of weeks

Experts in Heidelberg, Germany, have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more ...

No-needle test can tell if flu/COVID vaccines are effective

A team of researchers at the University of Pittsburgh has developed a skin patch that can detect antibodies associated with COVID and flu infections. It's orders of magnitude more sensitive than existing tests, uses just ...

Father–son team integrates AI into cancer research

For more than three decades, USF Distinguished University Professor Dmitry Goldgof in the Bellini College of Artificial Intelligence, Cybersecurity and Computing has been at the forefront of artificial intelligence research. ...

What happens when you donate your brain to science?

On a cutting surface inside a Scaife Hall laboratory at the University of Pittsburgh, Julia Kofler examines a brain, pointing out its weight, tiny specks of fatty plaque and other features visible even to the naked eye that ...

Blood markers linked to post-concussion symptoms in teens

Levels of certain biomarkers in the blood are associated with symptom severity during recovery from concussion in adolescents—with some significant differences between male and female patients, reports a study in the Journal ...

MAGIC: AI-assisted 'laser tag' illuminates cancer origins

The human body relies on precise genetic instructions to function, and cancer begins when these instructions get scrambled. When cells accumulate genetic errors over time, they can break free of the normal controls on their ...

3D genome mapping tool reveals hidden complexity in DNA

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new discoveries.