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Laboratory medicine news

Biopsy-derived cryo-EM structures reveal patient-specific amyloid fibrils

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, has revealed the high-resolution structures of amyloid fibrils directly extracted from biopsy samples ...

Stem cell expert Q&A: Innovative pathways in biomedical research

New scientific methods could one day render animal studies—the standard in research laboratories for more than 100 years—obsolete. Clive Svendsen, Ph.D., executive director of the Board of Governors Regenerative Medicine ...

Blood test reveals risk of multimorbidity in older adults

A small set of common blood biomarkers predicts which older adults will develop specific combinations of chronic diseases—and how quickly, according to a new study from Karolinska Institutet published in Nature Medicine.

Costs pose hurdle for promising new hepatitis C lab test

A new rapid test for hepatitis C could help identify many more patients who could be cured of the deadly disease, but its use may be limited unless insurers' reimbursement rises to cover its high cost, according to researchers ...

New ALS diagnostic blood test boasts 97% accuracy

ALS is a debilitating paralytic disease characterized as the death of upper and lower motor neurons. Fortunately, ALS is relatively rare, with an incidence rate of 1.6 per 100,000 adults, resulting in about 30,000 cases in ...

Your blood proteins could predict your risk of an early death

Imagine if a simple blood test could offer a glimpse into your future health. Not just whether you have heart disease or cancer today, but whether your overall risk of dying in the next five or ten years is higher or lower ...

Cell-free DNA could detect adverse events from immunotherapy

A noninvasive blood test to detect genetic material shed by tumors may help clinicians identify adverse events related to treatment with immune checkpoint inhibitor drugs, investigators at the Johns Hopkins Kimmel Cancer ...

Online tool detects drug exposure directly from patient samples

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete. People may forget what they took, use over‑the‑counter ...

Simple urine test developed to screen bladder cancer

Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive ...

Fibulin-5: A potential marker for liver fibrosis detection

When damage to the liver caused by alcohol or viral infections persists, liver fibrosis progresses and replaces tissue with collagen fibers. This is especially a risk in chronic hepatitis C patients, where liver fibrosis ...