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Laboratory medicine news

Faster aging, chronic disease linked to WTC responders with PTSD

Post-traumatic stress disorder (PTSD) remains a common condition affecting World Trade Center (WTC) responders 25 years after the attack on the Twin Towers. While the condition is considered mainly psychological, a new study ...

GenAI overcomes slide misalignment to produce virtual stains close to real slides

Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples.

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...

CT tissue images can now be virtually stained in 3D

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, ...

Therapeutic target for dangerous fungal infections identified

A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide ...

AI diagnoses brain tumors in minutes instead of weeks

Experts in Heidelberg, Germany, have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more ...

How a louse-borne pathogen evades the immune system

Louse-borne relapsing fever is caused by the spirochete bacterium Borrelia recurrentis, which is transmitted by body lice (not head lice). The disease was first described by Hippocrates (460–370 B.C.). Initial symptoms include ...

New medium offers faster, cheaper drug-resistance detection

A critical problem in treating Clostridioides difficile infections is the possibility that the pathogen develops resistance to fidaxomicin, an antibiotic often prescribed as a first-line treatment. But current methods used ...

Are you sleep deprived? Your spit may hold answer

Sleep loss dulls alertness and coordination, and it can produce effects similar to severe intoxication, making actions like driving incredibly risky. But there's no clinical test for determining when someone is dangerously ...

Can AI beat breast cancer?

An artificial intelligence (AI) system that combines breast cancer tissue images with molecular marker data achieves high accuracy in diagnosis, tumor classification, and survival prediction. Details of the research are reported ...

Blood test detects early signs of breast cancer recurrence

Researchers at Lund University have developed a blood test capable of detecting signs of breast cancer recurrence long before recurrence becomes visible on imaging or causes symptoms. It has previously been shown that this ...