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Laboratory medicine news

Warm nights linked to ill premature babies in NICUs

Premature babies in the intensive care unit are particularly at risk of becoming infected with potentially pathogenic bacteria. A team of doctors in Hanover has now investigated which external factors play a role in this. ...

Disrupted antioxidant balance linked to the development of 'Skellefteå disease'

Researchers at Umeå University have identified changes in the body's major antioxidant systems in patients with hereditary transthyretin (TTR) amyloidosis. The findings support the hypothesis that oxidative stress contributes ...

Hepatitis E viruses mutate early during infection

Knowing how viruses change in the initial weeks of an infection can provide important information about their adaptability. Researchers from the Departments of Molecular & Medical Virology and Translational & Computational ...

Epigenetic mapping provides deeper insight into leukemia

Researchers at Karolinska Institutet in Sweden and Kyoto University in Japan have identified new subgroups of the blood cancer acute myeloid leukemia. The study, published in the journal Nature, shows that changes in the ...

New brush test detects oral cancer in one hour

A paper published in the journal Biomarker Research by a cross-university team led by Queen Mary University of London researchers validates the use of a noninvasive brush biopsy test that can detect oral cancer within one ...

Blood test finds hidden pancreatic cancer after treatment

Northwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more ...

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...

CT tissue images can now be virtually stained in 3D

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, ...

Therapeutic target for dangerous fungal infections identified

A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide ...

AI diagnoses brain tumors in minutes instead of weeks

Experts in Heidelberg, Germany, have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more ...