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Laboratory medicine news

Blood proteins may offer new clues to gut health in celiac disease

Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.

Most labs testing children for cardiac troponin lack pediatric reference ranges, survey finds

Cardiac troponin, a protein released into the blood when heart muscle is damaged, can be used as a quick measure of heart injury in adults, and testing for it has revolutionized adult cardiology. For children, however, doctors ...

A new AI tool distinguishes Ewing sarcoma from similar tumors

A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated an artificial intelligence (AI) system capable of distinguishing Ewing sarcoma from other morphologically ...

Candy-coated Lollylab checks saliva for medication

What if checking medication levels were as simple as enjoying a lollipop? A candy-coated device called Lollylab could provide the answer. In ACS Sensors, researchers describe how the lollipop's stem transfers saliva to a ...

Hepatitis E viruses mutate early during infection

Knowing how viruses change in the initial weeks of an infection can provide important information about their adaptability. Researchers from the Departments of Molecular & Medical Virology and Translational & Computational ...

Epigenetic mapping provides deeper insight into leukemia

Researchers at Karolinska Institutet in Sweden and Kyoto University in Japan have identified new subgroups of the blood cancer acute myeloid leukemia. The study, published in the journal Nature, shows that changes in the ...

New brush test detects oral cancer in one hour

A paper published in the journal Biomarker Research by a cross-university team led by Queen Mary University of London researchers validates the use of a noninvasive brush biopsy test that can detect oral cancer within one ...

Blood test finds hidden pancreatic cancer after treatment

Northwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more ...

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...