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Laboratory medicine news

Updated guidelines standardize how tumor response is measured after surgery

Researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have released updated consensus guidelines and an associated reproducibility study to standardize how pathologists ...

How our lab is helping develop an Alzheimer's test that can be done at home

Imagine diagnosing one of the most challenging neurological diseases with just a quick finger-prick, a few drops of blood and a test sent in the post. This may sound like science fiction, but we are hoping our research could ...

Early signs of Parkinson's can be identified in the blood

A team led by researchers at Chalmers University of Technology, Sweden, has succeeded in identifying biomarkers for Parkinson's disease in its earliest stages, before extensive brain damage has occurred. The biological processes ...

A skin biopsy can detect a rare neurodegenerative disease

By determining the structure of the deposits responsible for transthyretin amyloidosis through a simple skin biopsy, scientists at UNIGE are paving the way for a new diagnostic method for neurodegenerative diseases. Transthyretin ...

AI can predict preemies' paths based on blood spot data

An artificial intelligence-based tool can predict the medical trajectories of individual premature newborns from blood samples collected soon after they are born, a Stanford Medicine-led study has shown.

Virtual histography: From tissue section to 3D image

Histology is one of the foundations of modern diagnostics. When physicians want to determine whether tissue is pathologically altered, they rely on microscopic tissue analysis: They cut the tissue into ultrathin sections, ...

Blood markers linked to post-concussion symptoms in teens

Levels of certain biomarkers in the blood are associated with symptom severity during recovery from concussion in adolescents—with some significant differences between male and female patients, reports a study in the Journal ...

MAGIC: AI-assisted 'laser tag' illuminates cancer origins

The human body relies on precise genetic instructions to function, and cancer begins when these instructions get scrambled. When cells accumulate genetic errors over time, they can break free of the normal controls on their ...

3D genome mapping tool reveals hidden complexity in DNA

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new discoveries.

RNA tech could make fast test for Alzheimer's disease

One of the most frightening things about Alzheimer's disease is how difficult it is to diagnose early. Now, University of Connecticut researchers report two fast tests for early markers of the disease in the journal Biosensors, ...

AI tool beats humans at detecting parasites in stool samples

Scientists at ARUP Laboratories have developed an artificial intelligence (AI) tool that detects intestinal parasites in stool samples more quickly and accurately than traditional methods, potentially transforming how labs ...

Multiple sclerosis linked with distinct oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome—the trillions of bacteria, fungi, and viruses that colonize our digestive tract—and the idea that keeping ...

Rethinking how bone marrow works with a unified framework

One huge reason why the world of medicine hasn't yet found "the cure" for hard-to-treat malignancies like acute myeloid leukemia (AML) and many other forms of cancer is that the world of science is still striving to fully ...