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Oncology news
Drug that targets an inflammatory enzyme could help prevent lung cancer
Every year, lung cancer kills more than 100,000 people in the United States. Smoking is the leading risk factor for lung cancer, but other environmental exposures can also contribute to the disease.
17 hours ago
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Genome analysis uncovers candidate genes for hereditary breast and ovarian cancer
Breast cancer is the most common form of cancer among women in Germany: Around 1 in 8 women will develop it during their lifetime. In around 5% to 10% of cases, the condition is caused by a hereditary predisposition. Thirteen ...
18 hours ago
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Breast cancers can recruit bone cells to increase tumor growth
Researchers at WashU Medicine have shown that cells originating in bone and best known for their role in bone formation are recruited to primary breast tumors, where they become cancer-associated fibroblasts, a type of cell ...
19 hours ago
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New mechanism may help predict and improve macrophage-targeted cancer immunotherapy
Immunotherapy that targets tumor-associated macrophages, a type of immune cell in the tumor microenvironment, works only if the cells have a functional system of molecules that enables them to respond to the treatment. This ...
16 hours ago
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Selenite changes key properties of pancreatic cancer cells in experimental models
Researchers at Karolinska Institutet report in the Journal of Experimental & Clinical Cancer Research that sodium selenite not only can damage tumor cells but also influence characteristics linked to tumor aggressiveness ...
18 hours ago
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Electric fields offer new hope against aggressive brain cancer
More than a decade ago, Dr. Matthew Hebb was treating patients with Parkinson's disease using deep brain stimulation by implanting tiny electrodes into the brain and delivering electrical signals to control tremors. He wondered ...
Aug 13, 2026
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Scientists uncover 'hidden switch' that helps cancer cells hide from the immune system
Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered a previously unknown mechanism that helps cancer cells evade detection by the body's ...
Aug 13, 2026
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Brain cancer cells exploit normal nerve signaling to multiply and invade, new study finds
Gliomas are malignant brain tumors that originate from glial cells, which do not produce electrical impulses like neurons but instead support neurons by maintaining their structure and function. They are the most common form ...
'Locked' cancer therapeutic activates in tumors, limiting off-target exposure in mice
Although there are many cancer treatments available today that effectively eliminate abnormal cells, these therapies may also damage healthy cells, leading to unwanted side effects.
Aug 13, 2026
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Rb's unexpected activation of estrogen-responsive genes could explain breast cancer treatment resistance
Researchers at Peter Mac have discovered why breast cancer treatment stops working for some patients, uncovering the unexpected role of one of the body's most important cancer-fighting proteins. The study, published in Nature, ...
Aug 13, 2026
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Cancer-specific c-Myc mapping reveals overlooked SLK protein as treatment target
Using a photochemically driven labeling technique, a Cornell-led research group has devised a strategy for capturing cancer-specific protein–protein interactions, which could one day lead to targeted therapies for prostate, ...
Aug 13, 2026
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Half of prostate cancer focal therapy use found to fall outside current guideline-supported groups
As focal therapy gains popularity as a less invasive treatment option for some men with prostate cancer, a national study led by researchers at the University of Pittsburgh found that some men may be receiving treatment that ...
Aug 13, 2026
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For early prostate cancer, 'active surveillance' is now the number 1 choice
Three decades after UC San Francisco pioneered "active surveillance" for patients with low-risk prostate cancer, a new study has found that the vast majority of veterans with the diagnosis pursued this option instead of treatment.
Aug 13, 2026
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Intermediate histotripsy dose boosts tumor regression in liver cancer model
Since its development at the University of Michigan more than two decades ago, histotripsy has progressed from an experimental method for mechanically destroying tissue to a US Food and Drug Administration (FDA)–cleared treatment ...
Aug 13, 2026
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AI digital twin platform advances personalized cancer treatment planning
A research team at The Hong Kong Polytechnic University (PolyU) has developed a patient-centric "Artificial Intelligence (AI) Virtual Patient Simulation System," overcoming the limitations of conventional static diagnosis.
Aug 13, 2026
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Researchers develop mathematical measures to better personalize therapy for prostate cancer
Researchers at Moffitt Cancer Center have developed three mathematical biomarkers that may help physicians personalize adaptive therapy for prostate cancer by predicting treatment outcomes early in treatment. The biomarkers ...
Aug 13, 2026
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Novel AI model accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Researchers have developed a novel AI model that can analyze a routine whole-slide histopathology image and simultaneously predict cancer subtype, specific genetic mutations and survival outcomes across 32 different solid ...
Aug 13, 2026
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ASTRO updates guideline on radiation therapy for pancreatic cancer
An updated clinical guideline from the American Society for Radiation Oncology (ASTRO) provides evidence-based recommendations on the use of radiation therapy to treat adult patients with pancreatic cancer.
Aug 13, 2026
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Regional differences in chemotherapy treatment for breast cancer may affect survival, Swedish study finds
The proportion of women with early breast cancer who receive chemotherapy varies significantly across different regions of Sweden. A study from Karolinska Institutet, published in the journal Breast Cancer Research, shows ...
Aug 13, 2026
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Personalized T-cell therapy eliminates detectable metastatic kidney tumor in adolescent after multiple relapses
Researchers and physicians at the Hopp Children's Cancer Center Heidelberg (KiTZ) and other leading cancer centers report an exceptional treatment outcome in an adolescent with an advanced, treatment-resistant kidney tumor. ...
Aug 12, 2026
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In vivo CRISPR screen identifies gene edits that strengthen CAR-T therapy against solid tumors
For patients with blood cancers like leukemia and lymphoma, the immunotherapy known as CAR-T cell therapy can be lifesaving. Doctors remove a patient's immune cells, called T cells, engineer them in the lab to better recognize ...
Aug 12, 2026
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Cancer protein p53 observed in action reveals more order than expected
Cancer occurs when cells divide uncontrollably and displace healthy cells. Tumor suppressors provide an important defense against this. As molecular growth inhibitors, they prevent healthy cells from becoming cancerous. A ...
Aug 12, 2026
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Discovering a new layer of control for a decades-old leukemia drug
For more than 70 years, the drug 6-thioguanine (6-TG) has been used to treat leukemia. Although its clinical effects have been studied extensively, scientists are still uncovering the molecular mechanisms that determine whether ...
Aug 12, 2026
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Finding a tumor's soft spot to power-up immunotherapy
Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of ...
Aug 12, 2026
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Ultra-processed foods linked to notably higher prostate cancer risks
Ultra-processed foods (UPFs) account for nearly 60% of adults' and 70% of children's energy intake in the United States. These industrially manufactured products—such as soft drinks, packaged cereals and snacks, and processed ...
Aug 12, 2026
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