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Oncology news
Dormant cancer cells can change shape to survive immune system attack
Cancer cells that have broken away from a primary tumor can lurk in the body for years in a dormant state, evading immune defenders and biding their time until conditions are ripe for establishing a new tumor elsewhere in ...
7 hours ago
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Study finds high blood pressure primes heart for damage from cancer drugs
Anthracyclines are among the most widely used chemotherapy drugs and have been a mainstay of cancer treatment for more than 30 years. Their extraordinary efficacy against numerous solid and hematologic tumors means that they ...
3 hours ago
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Sugar structures on kidney cells predict immune therapy response, study finds
Among modern cancer therapies, immune checkpoint inhibitors (ICI) are among the most successful treatment methods. These antibodies activate the immune system and enable T cells to detect and destroy tumor cells.
2 hours ago
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Researchers reveal interplay between chronic pancreatic inflammation and early cancer development
Pancreatic cancer is a rare disease; however, its initially inconspicuous symptoms and aggressive nature make it one of the deadliest forms of cancer.
6 hours ago
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Finding new cell markers to track the most aggressive breast cancer in blood
Of all the types of breast cancer, triple negative breast cancer (TNBC) is the most aggressive and lacks specific therapies. TNBC is also more likely to metastasize, or travel through the bloodstream to spread to other organs, ...
12 hours ago
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Potential tumor-suppressing gene identified in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining the pancreatic duct. Accounting for more than 90% of all pancreatic cancers, PDAC is extremely difficult ...
13 hours ago
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Novel theranostic model shows curative potential for gastric and pancreatic tumors
A newly developed radiopharmaceutical pair can precisely detect and effectively treat gastric and pancreatic tumors, completely eradicating tumors in certain preclinical models. Targeting the well-defined and accessible biomarker ...
8 hours ago
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Physical activity linked to breast tissue composition and stress markers in teens
Recreational physical activity may be associated with breast tissue composition and biomarkers of stress in adolescent girls, according to a new study from Columbia University Mailman School of Public Health and the Herbert ...
9 hours ago
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Predicting prostate cancer recurrence through power of AI
To help meet the potentially complex needs of patients after prostate cancer treatment and offer the precision and care necessary in the follow-up journey, Mayo Clinic's Department of Radiation Oncology developed the PSA ...
13 hours ago
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Trial reveals gene variant may affect prostate cancer drug efficacy
Data from a major U.S. clinical trial from the Alliance for Clinical Trials in Oncology has uncovered a genetic factor that may inform how to optimize the dosing of abiraterone, a widely used hormone treatment for advanced ...
13 hours ago
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The protein periostin may promote the spread of pancreatic cancer—and pain—through nerves
A new Brazilian study has revealed the key role of the protein periostin and stellate pancreatic cells in allowing pancreatic cancer to infiltrate nerves and spread early, increasing the risk of metastasis. The research demonstrates ...
Jan 14, 2026
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Gut bacteria molecule boosts lung cancer treatment response
UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing ...
Jan 14, 2026
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Bacterial toxin can counteract colorectal cancer growth
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University, Sweden. Systemic administration ...
Jan 14, 2026
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Study finds radiation therapy administered before surgery rarely shrinks retroperitoneal sarcoma tumors
According to new research, radiation therapy administered before surgery rarely produces favorable responses in patients with retroperitoneal sarcoma (RPS), a rare and aggressive cancer that forms in the abdomen. The study ...
Jan 14, 2026
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ctDNA levels after neoadjuvant therapy may predict breast cancer recurrence better than pathologic complete response
The presence of circulating tumor DNA (ctDNA) in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer after they received neoadjuvant treatment and surgery predicted worse outcomes than in ...
Jan 14, 2026
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Scientists identify pre-cancerous states in seemingly normal aging tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.
Jan 14, 2026
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Blood test predicts which patients with lung cancer will benefit from newly approved immunotherapy drug
A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting ...
Jan 14, 2026
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What does it mean to be in a cancer clinical trial?
Many people are surprised to learn that clinical trials aren't just for people who have run out of standard treatment options, but are an important part of cancer care at every stage and most aspects of diagnosis and treatment. ...
Jan 14, 2026
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From immune evasion to activation: A new cancer vaccine strategy
A research team led by Professor Chen Peng from the College of Chemistry and Molecular Engineering at Peking University has developed a novel cancer immunotherapy strategy that forces tumors to expose themselves to the immune ...
Jan 13, 2026
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AI model identifies how every country can improve its cancer outcomes
For the first time, researchers have used machine learning—a type of artificial intelligence (AI)—to identify the most important drivers of cancer survival in nearly all the countries in the world.
Jan 13, 2026
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Novel immunotherapy demonstrates early potential to overcome resistance to immune checkpoint therapy
According to a Phase I study led by researchers at The University of Texas MD Anderson Cancer Center, published in Nature Medicine, the novel monoclonal antibody linavonkibart has demonstrated the potential to overcome treatment ...
Jan 13, 2026
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New combination therapy developed for frequent form of lung cancer
A research team at the Medical University of Vienna has discovered a new approach to treating a particularly frequent and difficult-to-treat form of lung cancer. The study shows that a combination of two well-studied classes ...
Jan 13, 2026
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Blocking key enzyme to protect against fatty liver may raise cancer risk instead
Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age.
Jan 13, 2026
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AI advice matches physician recommendations in early-stage liver cancer, but falls short in late stage
Large language models (LLM) can generate treatment recommendations for straightforward cases of hepatocellular carcinoma (HCC) that align with clinical guidelines but fall short in more complex cases, according to a new study ...
Jan 13, 2026
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Disrupting HDAC1 condensates in glioblastoma could help to overcome drug resistance
Glioblastoma (GBM) is one of the most common and aggressive primary brain tumors in adults, carrying an extremely poor prognosis and a median overall survival typically less than two years. Temozolomide (TMZ) is currently ...
Jan 13, 2026
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