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Oncology news
New 'fishhook' bonds help T cells stick longer to prostate cancer cells
UCLA and Stanford Medicine researchers, in collaboration with scientists from the University of Utah and Columbia University, have engineered a new class of supercharged T cells that are stronger, longer-lasting, and more ...
16 hours ago
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Masked T‑cell engagers: Cancer immunotherapies for the future?
A new immunotherapy drug has demonstrated early promise in a recent prostate cancer clinical trial. The drug, called VIR-5500, is a "masked T-cell engager." This type of immunotherapy ignites our own immune arsenal to fight ...
11 hours ago
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Student shines a light on rare colon cancer
Colon cancer is one of the most common cancers in the U.S., with more than 100,000 cases diagnosed each year. But some people develop a highly aggressive form of colon cancer that is extremely rare, making up 0.02% to 0.1% ...
13 hours ago
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Awareness of alcohol-cancer link holds steady despite omission from new US dietary guidelines
Public awareness of the link between drinking alcohol and elevated cancer risk remains unchanged since February 2025, with over half of Americans saying that regularly consuming alcohol increases your chances of later developing ...
15 hours ago
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Research leads to new lifeline for leukemia patients
After repeated unsuccessful cancer treatments, even the strongest patients can lose hope. But former University of Virginia School of Medicine assistant professors Tomasz Cierpicki and Jolanta Grembecka are working to restore ...
8 hours ago
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A liquid biopsy blood test may improve children's survival of cancer in Africa
In a study published in Nature Medicine, researchers from the University of Oxford and the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es Salaam, Tanzania have shown that a minimally invasive liquid ...
Mar 19, 2026
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Long dismissed in adult health, the thymus may be critical for longevity and cancer treatment
Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant in adulthood. ...
Mar 18, 2026
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Scientists create cancer-fighting immune cells right in the body
For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an elaborate process: Doctors extract a patient's immune cells, ship them to a specialized facility where ...
Mar 18, 2026
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Antioxidant serves as an unexpected food source for tumors, scientists discover
Researchers have discovered an antioxidant, glutathione, that cancer cells appear to be "addicted to" as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient.
Mar 18, 2026
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Combination treatment benefits patients with advanced breast cancer that has spread to the brain
Patients with leptomeningeal metastasis (LM) have historically had few treatment options. Now, researchers from The University of Texas MD Anderson Cancer Center have found a combination of targeted therapies, tucatinib and ...
Mar 18, 2026
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Cholecystokinin, not insulin, may be key hormone in obesity-driven pancreatic cancer
Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels. Scientists have thought that this excessive insulin secretion ...
Mar 18, 2026
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Cellular stress signal found to drive immune exhaustion and weaken cancer therapy
Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress ...
Mar 18, 2026
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Why some breast cancers spread faster: Jagged1 may trigger a tissue-stiffening feedback loop
A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor tissue during breast cancer ...
Mar 18, 2026
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Cancer drug protein target may also help fight influenza
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX). Published in Cell Reports, the study found that Programmed Death-Ligand ...
Mar 18, 2026
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Novel X-ray technique could transform tissue diagnosis
A new X-ray imaging technique could transform how hospitals analyze tissue samples, potentially speeding up diagnoses and improving outcomes for patients, shows a new study led by UCL researchers. The technology, developed ...
Mar 18, 2026
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HPV vaccination protects girls living with HIV in South Africa, study shows
New research shows first population-level evidence globally that a national HPV vaccination program can be highly effective in a high HIV-prevalence setting. In South Africa, where the burden of HIV remains high, women living ...
Mar 18, 2026
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Perfluorooctanesulfonic acid, perfluoroheptanoic acid, mono-iso-nonyl-phthalate can predict lung cancer mortality
A model composed of perfluorooctanesulfonic acid (PFOS), perfluoroheptanoic acid (PFHA), and the plasticizer mono-iso-nonyl-phthalate can predict lung cancer mortality, according to a study published online March 4 in Clinical ...
Mar 18, 2026
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Cancer research at a crossroads: Experts warn against funding cuts and misinformation
A new editorial published in JAMA Oncology warns that cancer care progress is under threat from a trifecta of challenges: proposed federal budget cuts, a surge in medical misinformation, and a critical gap in public health ...
Mar 18, 2026
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Surgery plays a central role in treatment for colorectal cancer—and is usually the first step
When someone is diagnosed with colorectal cancer—which includes both colon and rectal cancers—many people immediately think "surgery." And it's true that surgery plays a central role in treatment for most patients. But ...
Mar 18, 2026
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Understanding the role of the protein PAX3 in cancer development
Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression. While progress ...
Mar 18, 2026
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Study identifies inflammatory immune pathway driving immunotherapy resistance in bladder cancer
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy. Their ...
Mar 18, 2026
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New study identifies how obesity-related liver cancer becomes more aggressive and resistant to treatment
A research team affiliated with UNIST has made a significant discovery explaining why liver cancers associated with obesity and metabolic disorders tend to be more aggressive and less responsive to conventional treatments. ...
Mar 18, 2026
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Brain tumors hijack sugar metabolism to evade immune attack, study shows
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published in the Proceedings ...
Mar 17, 2026
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'Junk DNA' may help defend against colorectal cancer
For decades, large portions of the human genome were labeled "junk DNA." New research from Western University and London Health Sciences Centre Research Institute (LHSCRI) suggests these overlooked sequences may help protect ...
Mar 17, 2026
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Hidden drug reservoirs in cancer cells could explain treatment resistance
One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in Nature Communications, by a multidisciplinary team led by Dr. Louise Fets ...
Mar 17, 2026
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