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Oncology news
Dual therapy activates immune defenses while damaging lung cancer DNA
A new preclinical study has demonstrated that combining HER3-DXd with olaparib significantly improves treatment responses in lung cancer models. This combination therapy induces irreparable DNA damage in cancer cells while ...
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Immunotherapy shows promise for clearing residual melanoma cells
Cornell researchers successfully ramped up the body's own immune response to fight melanoma at the tail end of targeted cancer therapy, when tumors commonly become resistant to these therapies and leave behind residual cancer ...
28 minutes ago
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Blood test shows promise for detecting breast cancer recurrence
A research team at Kumamoto University has developed a blood-based approach that could help detect breast cancer recurrence by looking beyond conventional genetic mutations and examining how DNA is packaged inside cells. ...
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New drug targets offer potential pathway for pancreatic cancer treatment
Peter Mac researchers have identified potential new drug targets for pancreatic cancer by uncovering proteins cancer cells rely on to grow and survive.
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Robot-assisted surgery shows clinical advantages over laparoscopic surgery for gastric cancer
Surgery remains the primary curative treatment for gastric cancer, with laparoscopic gastrectomy (LG) established as a standard minimally invasive approach. While LG offers faster recovery than open surgery, it remains technically ...
3 hours ago
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Late diagnosis and limited care drive gynecologic cancer-related deaths in low- and middle-income countries
Low- and middle-income countries (LMICs) bear a disproportionate burden of gynecologic malignancies—cancers of the cervix, endometrium, ovary, vagina and vulva. A review published in CANCER reveals that survival disparities ...
9 hours ago
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Personalized vaccine helped melanoma patients stay cancer-free longer, drugmakers say
An experimental vaccine kept melanoma from returning or spreading in people at high risk of the skin cancer recurring, drugmakers Moderna and Merck announced Wednesday.
15 hours ago
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Previously missed DNA mutation pattern in colorectal cancer identified
Researchers from the University of California San Diego and collaborators have identified a previously overlooked pattern of DNA mutations in colorectal cancer. Scientists use these patterns, known as mutational signatures, ...
Aug 22, 2026
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Oral therapy protected mice from lethal radiation while sparing cancer treatment
Researchers at the Fralin Biomedical Research Institute at VTC have developed an experimental oral therapy that protected mice from otherwise harmful radiation exposure while preserving radiation's ability to destroy cancer ...
Aug 22, 2026
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First-in-class therapy targets 'undruggable' protein in hard-to-treat blood cancers
A first-in-class therapy to target MYC, one of the most sought-after and difficult targets in cancer biology, showed promise in hard-to-treat blood cancers, according to a new preclinical study from The University of Texas ...
Aug 22, 2026
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How lung tumors hijack an ancient marine metabolic axis to promote malignant growth
Researchers at the Institute of Oceanology of the Chinese Academy of Sciences (IOCAS) have shown how a metabolic mechanism underlying thermal tolerance in intertidal oysters sheds light on malignant proliferation in human ...
Aug 22, 2026
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Lung cancer patient becomes tumor-free after treatment with sodium selenite
A patient with advanced, treatment-resistant lung cancer became tumor-free after treatment with the selenium compound selenite. This is shown in a new study from Karolinska University Hospital and Karolinska Institutet published ...
Aug 21, 2026
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Scientists identify molecule driving one of the deadliest forms of breast cancer
Australian researchers have uncovered a promising new way to tackle one of the most aggressive forms of breast cancer, raising hopes for more effective treatments to stop the disease from spreading.
Aug 21, 2026
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New drug combination may help treat advanced prostate cancer
About 1 in 8 men are diagnosed with prostate cancer during their lifetime. Although many survive, it can develop into metastatic disease.
Aug 21, 2026
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Super-resolution microscopy reveals how a cancer drug triggers cellular breakdown
Cancer drugs are often designed to block specific molecular targets, but what happens after they enter a cell is not always well understood. A new study published in Biophotonics Discovery demonstrates how advanced imaging ...
Aug 21, 2026
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How loss of tumor suppressor drives ER+ breast cancer to metastasize to the bone
A Baylor College of Medicine-led team has uncovered how loss of tumor suppressor neurofibromin (NF1) in estrogen receptor-positive (ER+) breast cancer cells drives the cells' preference to metastasize to bone.
Aug 21, 2026
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Younger adults with lung cancer more likely to have targetable genetic changes, study finds
Younger adults with non-small cell lung cancer are significantly more likely than older patients to have genetic alterations that can be matched with targeted therapies, according to a large international study led in part ...
Aug 21, 2026
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Drugs developed in China reaching international markets, research finds
China has become an increasingly important contributor to pharmaceutical development, but comparatively little attention has been paid to how successfully medicines developed in China have entered major international markets.
Aug 21, 2026
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Preoperative chemo and immunotherapy combo shrinks head, neck cancer tumors
Combining chemotherapy with immunotherapy before surgery for head and neck cancer is associated with significantly greater reductions in tumor size than immunotherapy alone, according to a study published online Aug. 13 in ...
Aug 21, 2026
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Study points to broader stem cell donor options for blood cancer patients
For decades, stem cell transplantation has operated under a simple rule: The closer the donor match, the better. Patients with leukemia, lymphoma, myelodysplastic syndromes and other blood cancers often faced an extensive ...
Aug 21, 2026
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Cancer drug strategy flips script: PRMT1 activator boosts chemotherapy in pancreatic cancer mouse study
What if we could fight cancer by specifically activating a key enzyme instead of deactivating it? That's exactly what a research team at Marburg University has achieved for the first time with the enzyme PRMT1. The scientists ...
Aug 21, 2026
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Study shows lack of awareness for lung cancer screenings across country
Lung cancer screenings can save lives by detecting cancer in its early stages, but only 15% of eligible American adults have discussed the screening with their doctors, according to data analysis performed by University of ...
Aug 21, 2026
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In cancer clinical trials, federal and industry sponsors play complementary roles
A comparative study of the cancer clinical trial portfolios supported by federal funding versus industry funding reveals they have distinct, interdependent roles in cancer research.The work, "Federal and Industry Sponsorship ...
Aug 21, 2026
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Exploring precision medicine for pancreatic cancer
Imagine if, before starting cancer care, doctors could rapidly identify the most effective chemotherapy, immunotherapy or combination to personalize treatment for a loved one's hard-to-treat pancreatic cancer and improve ...
Aug 21, 2026
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Lung tumor bacteria plus vitamin B2 metabolite may boost immune response to cancer
Bacteria in lung tumors may boost the activation of innate immune cells in the presence of a common vitamin metabolite, according to a preclinical study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel ...
Aug 20, 2026
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