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Oncology news
FDA-approved cancer drug fedratinib reshapes how cell organelles communicate, providing new therapeutic avenues
Cells behave like cities and organelles carry out infrastructural roles: mitochondria are powerhouses, the endoplasmic reticulum serves as a transport hub and lysosomes help with waste disposal. Communication between different ...
23 hours ago
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GLP-1 receptor agonists linked to lower mortality for patients with brain metastases, T2DM
For patients with cancer and brain metastases (BM) and type 2 diabetes (T2D), glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is associated with significantly lower all-cause mortality, according to a research letter ...
17 hours ago
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How vitamin B2 could pave the way to new cancer therapies
The human body cannot produce vitamin B2—also known as riboflavin—itself; it must absorb the important substance through diet. The vitamin can be found in dairy products, eggs, meat and green vegetables. The metabolism ...
Mar 13, 2026
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Multi-cytokine scaffold helps CAR-T cells fight cancer and HIV for longer
A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells that dramatically prolongs their effectiveness after being infused into patients to fight cancer ...
Mar 13, 2026
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A new triple negative breast cancer target: Why HORMAD1 could guide treatment choices
A gene that is typically active only in reproductive cells may hold the key to new treatments for triple negative breast cancer, according to new research published in the journal Nature Communications. Scientists from the ...
Mar 13, 2026
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Enzyme-blocking cream may prevent or slow growth of some common skin cancers, preclinical study reveals
A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), according to a study published in the Journal of Clinical Investigation.
Mar 13, 2026
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Sonodynamic therapy is safe and well-tolerated in high-grade gliomas, first-in-human trial suggests
High-grade gliomas, especially glioblastoma (GBM) and others, remain among the most aggressive brain cancers, with few effective treatment options after the tumor recurs. Even with maximal surgical resection, radiotherapy, ...
Mar 13, 2026
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Dual targeting approach improves immunotherapy response in glioblastoma
Researchers from The University of Texas MD Anderson Cancer Center have found that simultaneously blocking two key "don't eat me signals" found in cancer cells heightens the immune response and sensitizes tumors to immunotherapy ...
Mar 13, 2026
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Study finds CDK4/6 plus EGFR blockade kills pancreatic cancer cells without KRAS drugs
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 inhibition offers an indirect ...
Mar 13, 2026
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Bilingual forms improve cancer treatment understanding among people with limited English
People with limited English are significantly more likely to understand the true aim of cancer treatment when given a bilingual consent form, with understanding rising from 35% to 60%, a new study finds. The study, published ...
Mar 13, 2026
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How 3D and mixed reality can transform bone cancer surgery
When a patient is diagnosed with osteosarcoma, an aggressive form of bone cancer, the mission is to remove the tumor entirely. Leaving behind even a microscopic cluster of malignant cells can be the difference between remission ...
Mar 13, 2026
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Prenatal stem cell treatment targets rare genetic disease before birth
Stanford Medicine pediatric hematologist Agnieszka Czechowicz, MD, Ph.D., has devoted her research career to improving treatments for rare blood disorders. She's an expert in Fanconi anemia, a genetic disease that interferes ...
Mar 13, 2026
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Uncovering a key signaling pathway linking liver cancer and fibrosis
New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better treatment strategies, report researchers from Institute of Science Tokyo. Through a comprehensive analysis ...
Mar 13, 2026
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New strategy intercepts pancreatic cancer by eliminating microscopic lesions before they become cancer
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors. Using an experimental therapy to target microscopic precancerous lesions in the ...
Mar 12, 2026
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Scientists find a new therapeutic target present on up to half of all tumors
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden ...
Mar 12, 2026
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First-of-its-kind analysis reveals the structural variant landscape driving pediatric cancer development
The first and largest dataset of genomic structure variations specific to childhood cancers was published today by scientists from St. Jude Children's Research Hospital and the National Cancer Institute. The researchers assembled ...
Mar 12, 2026
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Tuning T cells' cancer-killing power via an engineered hydrogel platform
Lymph nodes, considered the command centers of our immune system, often get swollen and stiff when fighting infection. Now, a UC Berkeley-led team of researchers has discovered that this mechanical change may help instruct ...
Mar 12, 2026
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Novel tool measures how cancer cells rewrite genetic instructions to aid growth and survival
Cancer is caused by faulty genes, but what also shapes a cancer cell's behavior is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive. A study published in ...
Mar 12, 2026
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Romiplostim prevents serious side effect of chemotherapy in phase 3 trial
Results from a global phase 3 clinical trial led by investigators at Mass General Brigham show that the medication romiplostim can effectively prevent chemotherapy from destroying platelet-producing bone marrow cells, a common ...
Mar 12, 2026
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New atlas that charts tumor cell diversity could guide personalized therapy for head and neck cancer
Head and neck squamous cell carcinomas (HNSCC) are the seventh-most prevalent form of cancer and are associated with human papilloma virus infection (HPV-positive) or with tobacco and alcohol use (HPV-negative). HPV-negative ...
Mar 12, 2026
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Personalized support program improves smoking cessation for cervical cancer survivors
A new study led by UCLA researchers suggests that a personalized counseling program can significantly help women who have survived cervical precancer or cervical cancer to quit smoking—and does so at a cost that researchers ...
Mar 12, 2026
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Trial finds immunotherapy did not improve survival when added to chemoradiotherapy for small cell lung cancer
Immunotherapy given during and after chemoradiation did not improve survival for study participants with limited-stage, small-cell lung cancer (SCLC) according to the results of an international clinical trial, NRG-LU005, ...
Mar 12, 2026
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Prostate cancer deaths to decrease, researchers predict
Prostate cancer is one of the leading causes of cancer-related death in men, and some experts project the number of cases to rise over the coming decades. But in a recent Urologic Oncology article, Yale School of Medicine ...
Mar 12, 2026
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Higher burnout rates among physicians who treat sickle cell disease
Hematology-oncology-trained physicians who treat sickle cell disease reported higher rates of burnout (60%) than their counterparts who do not provide sickle cell care (43%) despite no differences in grit and resilience between ...
Mar 12, 2026
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Structured exercise programs may help combat 'chemo brain' according to new study
New research suggests that exercise may help people with cancer stay mentally sharp and better able to handle daily tasks, work, and social activities through chemotherapy treatment delivered on an every two-week cycle. This ...
Mar 12, 2026
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