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Oncology news
Common metabolic enzyme could predict cancer immunotherapy benefits—and help more patients respond
Immunotherapies have transformed cancer treatment by helping the immune system recognize and attack tumors. They work for only about 20% of patients, though, and doctors still struggle to predict who will benefit.
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Heat-activated skin patch can kill melanoma cells without surgery
Melanoma is a deadly form of skin cancer that is typically removed surgically. Now, researchers publishing in ACS Nano report they have developed a potential noninvasive treatment for melanoma in the form of a stretchy, heat-activated ...
25 minutes ago
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Pesticides and cancer: Study reveals the biological mechanisms behind an environmental health risk
A new study, published in Nature Health, reveals a strong link between exposure to agricultural pesticides in the environment and the risk of developing cancer. By combining environmental data, a nationwide cancer registry, ...
7 hours ago
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ASH releases clinical practice guidelines on diagnosis and management of severe, very severe acquired aplastic anemia
The American Society of Hematology (ASH) released guidelines on the diagnosis and management of severe acquired aplastic anemia, a rare and life-threatening bone marrow failure disorder. The guidelines, developed by a multidisciplinary ...
2 hours ago
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New, more effective delivery method for eye cancer treatment is derived from pig semen
Getting past the barrier surrounding the eye is a difficult but necessary part of treating retinoblastoma (RB)—a form of eye cancer that is more common in children. Once the barrier is penetrated, RB responds well to treatment. ...
Cysteine pathways help T cells choose between multiplying and attacking tumors
A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health has discovered how the immune system's CD8+ T cells ...
17 hours ago
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TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds
A study by researchers at the University of California San Diego could make it easier to treat breast cancer by uncovering a new way the body helps prevent its spread. The scientists discovered a new role for an inflammatory ...
18 hours ago
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Discovery of pancreatic tumor vulnerability could pave the way for new treatments
A team from the Research Institute of the McGill University Health Center (The Institute), led by Jean-Jacques Lebrun, Ph.D., has identified a protein that pancreatic cancer cells rely on to survive and grow. This discovery ...
17 hours ago
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Shields and bodyguards: Scientists uncover the hidden defenses of a deadly childhood cancer
Researchers have created a detailed map of a deadly childhood cancer, showing it uses "shields" and "bodyguards" to protect itself, paving the way for new treatments. The team's paper, titled "Spatial multi-omics characterization ...
18 hours ago
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Hospital stay or home care? AI helps tailor myeloma stem cell treatment safely
Multiple myeloma is a cancer in which plasma cells, which normally produce antibodies, multiply uncontrollably in the bone marrow. There is currently no cure. However, various therapies can stabilize the disease and alleviate ...
19 hours ago
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Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers
Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published ...
18 hours ago
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Study finds 10-plus genetic markers tied to early follicular lymphoma relapse
Follicular lymphoma (FL) is a type of blood cancer and a form of non-Hodgkin's lymphoma. Thanks to new treatment breakthroughs, about 80% of FL patients have a survival rate of more than 10 years. The other 20%, however, ...
16 hours ago
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Surgeon highlights breast cancer screening challenges for women with dense breast tissue
A new editorial by a Uniformed Services University (USU) faculty member calls attention to challenges in breast cancer screening that may disproportionately affect active duty women and have implications for military readiness. ...
21 hours ago
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Cancer risk rises with autoimmune disorders but drops after anti-inflammatory therapy, finds study
When patients start getting treated for conditions like psoriatic arthritis, or connective tissue diseases like lupus and systemic sclerosis, their heightened risk of cancer gradually decreases, according to a new five-year ...
22 hours ago
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Unexpected findings on lung cancer CT scans may point to other non-lung cancers
When doctors review diagnostic medical scans for lung cancer, they sometimes spot abnormalities unrelated to the lungs. New research shows that some of those abnormalities could be signs of other undiagnosed cancers. The ...
Mar 31, 2026
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3 million-cell map shows menopause reshapes breast tissue, possibly raising cancer risk
Scientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age—including dramatic changes during menopause.
Mar 31, 2026
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PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds
Where previous research showed that PSMA therapy for prostate cancer can prolong the lives of patients who have exhausted all other treatment options, a new study now demonstrates that the therapy is also effective in an ...
Mar 31, 2026
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Prioritizing potentially cancer-causing mutations in real-world cancer genomics
Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number of variants of uncertain significance (VUS) detected in comprehensive genomic profiling ...
Mar 31, 2026
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Strongest evidence yet that vaping likely causes cancer
As early as the 1880s, there was evidence that smoking tobacco damaged your lungs. But it took almost 100 years to definitively show that smoking causes lung cancer.
Mar 31, 2026
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Vaping is likely to cause cancer, say new findings
Nicotine-based vapes (e-cigarettes) are likely to cause cancers of the lung and oral cavity, according to a new study led by UNSW Sydney and published today in Carcinogenesis. The study is titled "The carcinogenicity of e-cigarettes: ...
Mar 30, 2026
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An avatar to study pediatric brain cancer may soon be a reality
Biopsy-derived organoids, accurate models of disease, are used to search for new drugs. Now, results obtained by a study led by the University of Trento in collaboration with Bambino Gesù Children's Hospital in Rome may pave ...
Mar 30, 2026
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uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice
Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two main reasons: Tumor ...
Mar 30, 2026
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New analytical method reveals how drug combinations act in leukemia
Acute myeloid leukemia (AML) remains one of the most difficult blood cancers to treat. Although drug combinations are often more effective than single agents, their true mechanisms of action have been poorly understood. A ...
Mar 30, 2026
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Single-drug treatments are giving way to combination therapy for lung cancer
Combination therapy is essentially a one-two punch at cancer—sometimes with multiple punches. For people with lung cancer, it means treating a tumor with more than one type of therapy at the same time or in sequence, often ...
Mar 30, 2026
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After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse
Results of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a lower risk of relapse and lower rates of graft-versus-host disease when they receive the targeted therapy ...
Mar 29, 2026
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