Trojan horse delivery system uses gold nanoparticles to drive mRNA into tumors
University of Oklahoma researchers have created a new drug delivery system that helps cancer cells take in much more of a treatment, improving its ability to kill tumors. The findings are published in Science Advances.
10 hours ago
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AI tool predicts brain age, cancer survival and other disease signals from unlabeled brain MRIs
Mass General Brigham investigators have developed a robust new artificial intelligence (AI) foundation model that is capable of analyzing brain MRI datasets to perform numerous medical tasks, including identifying brain age, ...
12 hours ago
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Approved arrhythmia drug may slow MYC-driven lymphoma by blocking USP11 interactions
A team of researchers at VCU Massey Comprehensive Cancer Center discovered an innovative way to use a drug already approved for treating irregular heartbeat to selectively target specific functions of enzymes in lymphoma, ...
10 hours ago
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Five mutational 'fingerprints' could help predict how visible tumors are to the immune system
Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's not simply the number of tumor mutations that matters for immunotherapy, but the kind of mutation ...
7 hours ago
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FDA approves quadruplet regimen for adults with newly diagnosed multiple myeloma
The U.S. Food and Drug Administration has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj) in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for the treatment of adult patients with newly ...
9 hours ago
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Testing menstrual blood for HPV could be 'robust alternative' to cervical screening
Testing menstrual blood for human papillomavirus (HPV) could be a "robust alternative or replacement" for current cervical cancer screening by a clinician, finds a study from China published by The BMJ. The researchers say ...
22 hours ago
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A reliable atlas of cell types found in breast cancers
Breast cancer (BC) is the most common cancer and the second leading cause of cancer death in women. It is a highly variable disease, defined as a malignancy of the epithelial ducts in breast tissue. Characterizing the vast ...
23 hours ago
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A genetic blueprint for avoiding killer T cell exhaustion
A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune ...
Feb 4, 2026
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Small molecule blocks key glioblastoma driver, raising hopes for new treatment
UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for the deadliest brain cancer. ...
Feb 4, 2026
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An off-the-shelf immunotherapy for targeting solid tumors: Ready-to-use CAR-NKT cells show promise
A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to treat multiple solid tumors. The study focused on engineered invariant natural killer T cells, or ...
Feb 4, 2026
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A double-edged sword: Chronic cellular stress promotes liver cancer—but also makes tumors vulnerable to immunotherapy
A key molecular mechanism drives the growth of liver cell cancer while simultaneously suppressing the body's immune response to the tumor. This has been published in the journal Nature by a team led by researchers from the ...
Feb 4, 2026
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High consumption of ultraprocessed foods may be linked to cancer survivors' risk of death
Ultraprocessed foods can be considered unhealthy because they are often low in essential nutrients such as vitamins, minerals, and fiber, and the industrial processing methods used to produce them introduce additives, artificial ...
Feb 4, 2026
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Agent Orange exposure identified as a risk factor for rare skin cancer
A study of U.S. veterans led by investigators at Mass General Brigham has identified a possible link between exposure to the Agent Orange herbicide and a rare melanoma subtype less likely to be related to sun exposure. The ...
Feb 4, 2026
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Personalized palliative care shows signs of improving quality of life for children with advanced cancer
How to reduce suffering in children with advanced cancer remains an ongoing but urgent question. A Mass General Brigham-led study has examined whether systematically surveying children with advanced cancer and their parents ...
Feb 4, 2026
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Updated guidelines standardize how tumor response is measured after surgery
Researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have released updated consensus guidelines and an associated reproducibility study to standardize how pathologists ...
Feb 4, 2026
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Could fecal transplants be the new way to fight cancer?
One person's waste could be another's shot at fighting cancer. The idea may sound far-fetched, but it is gaining momentum in cancer care. Researchers are testing fecal microbiota transplants as a way of changing the gut's ...
Feb 4, 2026
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Doctors hope UK archive can solve under-50s bowel cancer mystery
In a dusty hospital basement on the outskirts of London, over 100 years of medical history lines the shelves, neatly arranged in row after row of cardboard specimen boxes.
Feb 4, 2026
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Two in five cancers worldwide are likely preventable, says new research
Nearly 40% of new cancer cases worldwide in 2022 may be associated with modifiable risk factors, according to an analysis of 36 cancer types from 185 countries. The findings suggest that reducing exposures such as tobacco ...
Feb 3, 2026
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RNA molecule discovery could lead to potential new breast cancer therapy
QIMR Berghofer scientists have discovered a cancer-fighting RNA molecule that could hold the key to a new way of treating the most common form of breast cancer. The team are developing their findings into a potential RNA-based ...
Feb 3, 2026
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Pancreatic tumors eliminated in mice without resistance developing
Current drugs for pancreatic cancer lose effectiveness within months because the tumor becomes resistant. Now, a group from Spain's National Cancer Research Centre (CNIO) has been able to avoid the development of resistance ...
Feb 3, 2026
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A fungus living in our body can make melanoma more aggressive
Cancer is one of the causes responsible for the most deaths worldwide. In 2020, for example, it resulted in ten million deaths. It has been estimated that microorganism infections caused between 13 and 18% of these cases. ...
Feb 3, 2026
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Epigenetic therapy could 'switch off' cancer genes for good
Monash University researchers, in collaboration with Harvard University, have discovered how to permanently "switch off" cancer-causing genes, revealing a new approach to cancer treatment. The breakthrough, published in the ...
Feb 3, 2026
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Yeast cells can be used for rapid testing of cancer immunotherapy
An international research team with strong participation from DTU has developed a new biotechnological platform that makes it possible to test and understand advanced cancer treatments much faster and cheaper than before. ...
Feb 3, 2026
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