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Oncology news
Shifting immune cells toward cancer-fighting mode: Sugar-coated extensions reveal a potential target
Our bodies contain immune cells called macrophages. Normally, these cells attack and suppress bacteria and cancer cells. However, when macrophages infiltrate tumors, they can become tumor-associated macrophages (TAMs) and ...
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Scientists uncover two-pronged strategy to overcome glioblastoma's resistance to immunotherapy
Scientists at The Wistar Institute have identified a combination treatment that overcomes two of the biggest barriers to immunotherapy in glioblastoma. In a study published in Neuro-Oncology, the researchers show that reprogramming ...
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Automated breast ultrasound is effective alternative to handheld ultrasound for breast cancer screening, study finds
A new study in the Journal of the American College of Radiology has found that automated breast ultrasound (ABUS) and handheld ultrasound (HHUS) had similar cancer detection rates in women with dense breasts, while ABUS had ...
1 hour ago
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Ancient viral DNA helps embryonic stem cells grow—and cancer hijacks the same switch
Three years ago, George Kassiotis and his team made an unexpected discovery: A specific way of producing a protein called calbindin was found to help cancer cells survive by preventing them from aging. This left Kassiotis, ...
7 hours ago
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More men living longer with incurable prostate cancer, report finds
Men in England diagnosed with incurable advanced prostate cancer are more likely to survive for at least three years than they were a decade ago, according to an analysis by the London School of Hygiene & Tropical Medicine ...
5 hours ago
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Randomized trial finds targeting individual metastases in oligometastatic breast cancer does not improve survival
Treating individual metastatic tumors with highly focused radiation or surgery did not improve progression-free or overall survival for patients with oligometastatic breast cancer receiving first-line systemic therapy, according ...
6 hours ago
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Cervical cancer trial finds similar early recovery results after robot-assisted versus open surgery
In early-stage cervical cancer, radical hysterectomy is an established treatment. The operation can be performed either through open surgery or robot-assisted minimally invasive surgery. Until now, there have been limited ...
6 hours ago
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Current age-based genetic testing in patients with cancer may miss the majority of inherited gene variants
Germline genetic screening can identify whether a patient with cancer has inherited genetic alterations in a gene or genes that are implicated in cancer. These inherited genetic alterations, known as germline pathogenic variants, ...
17 hours ago
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Children living with sickle cell can be treated safely using hydroxyurea, 10-year trial finds
New research shows the efficacy and safety of hydroxyurea treatment for sickle cell anemia at four low-income sites in Africa, with no increase in clinically diagnosed infections.
23 hours ago
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Key driver of aggressive prostate cancer identified, suggesting new way to reverse drug resistance
Researchers at Fred Hutch Cancer Center have identified a previously overlooked molecular regulator that helps determine whether prostate tumors remain sensitive to treatment or evolve into a more aggressive, drug-resistant ...
Oct 7, 2026
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Low-risk prostate tumors reveal molecular signs linked to more aggressive cancer
A new study revealed molecular features linked to more aggressive prostate cancer in a subset of patients who had been classified as low risk, highlighting biological differences that may not be apparent from clinical measures ...
Oct 7, 2026
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Experimental cancer treatment disrupts cell communication to suppress tumor growth in animal tests
A research team has developed an anticancer treatment platform that simultaneously targets cancer cells and the surrounding cells that support them while blocking communication between the two.
Oct 7, 2026
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Mitochondrial DNA levels reveal links to tumor growth and chemotherapy-related gene activity
Mitochondria are small organelles within cells that play a central role in vital cellular processes, especially energy production. Mitochondria contain their own DNA molecules (mtDNA) that are essential for mitochondrial ...
Oct 7, 2026
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Gene expression linked to survival differs by kidney cancer subtype
Renal cell carcinoma (RCC) is the most common form of kidney cancer, accounting for about 90% of kidney cancers. It develops when abnormal cells in the kidney's small tubules begin to grow uncontrollably. RCC has several ...
Oct 7, 2026
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Cancer trial drug may work differently than scientists believed, raising concerns for clinical research
A cancer drug currently being tested in patients may have entered clinical trials based on an incorrect understanding of how it works, according to a new study led by the University of Sydney in collaboration with Goethe ...
Oct 6, 2026
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New HPV selection method could help develop more stable, easier-to-produce vaccines
It's recommended that all adolescents get vaccinated against human papillomavirus (HPV), as the infection can cause cancer. HPV causes nearly all cases of cervical cancer and about 70% of some forms of head and neck cancers. ...
Oct 6, 2026
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Tumor markers reveal which HER2+ breast cancer patients may respond to less intensive chemotherapy
The Journal of Clinical Oncology has published secondary results from the ECOG-ACRIN Cancer Research Group's CompassHER2-pCR clinical trial (EA1181, NCT04266249). The findings help identify which early-stage HER2-positive ...
Oct 6, 2026
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Be wary of online nutrition advice for cancer patients
Avoid dairy, fruit and red meat; take vitamin D supplements—these are some of the nutrition claims circulating online for breast cancer patients, but how many of them are actually based on fact?
Oct 6, 2026
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International consensus sets updated framework for CAR T-cell therapy in severe autoimmune diseases
An international multidisciplinary group of 31 experts has updated consensus recommendations to guide the use of CAR T-cell therapy in patients with severe, treatment-refractory autoimmune diseases.
Oct 6, 2026
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One dose of protein-targeting CAR-T cells shrinks solid tumors in preclinical tests
CAR-T cell therapies have fundamentally transformed the treatment of several blood and lymph node cancers. However, their use in solid tumors such as liver, breast or lung cancer has so far been significantly more difficult. ...
Oct 5, 2026
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Cigarette smoke may prime lung stem cells for different types of lung cancer
Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene alterations and ultimately ...
Oct 5, 2026
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Making pediatric cancer more 'visible' boosts immunotherapy response
High-risk neuroblastoma is one of the most aggressive forms of solid tumors affecting children, originating in the nervous system. While a newer class of targeted immunotherapy drugs has improved survival rates, according ...
Oct 5, 2026
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Scientists study breast milk as an early detection tool for breast cancer
A new study taking place in Manchester is investigating whether breast milk could help detect breast cancer earlier than a blood test or a scan. The research, led by scientists at The University of Manchester, aims to improve ...
Oct 5, 2026
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Most women know about breast cancer risk factors, but fewer act on them
According to a new survey, most U.S. women understood breast cancer risk factors, but only a minority were taking action to help lower their risk.
Oct 5, 2026
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C. diff carriers without symptoms fuel most transmission in cancer wards, model finds
In a new study, researchers modeled the transmission of Clostridioides difficile (C. diff) infections among patients in hospital cancer units. They found that most new infections were introduced by patients who were infected ...
Oct 5, 2026
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