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Oncology news
Three-drug combo targets immune suppression to overcome melanoma resistance
For patients with advanced melanoma without BRAF mutation who no longer respond to immune checkpoint inhibitors, treatment options remain frustratingly limited. A new study from Vanderbilt researchers led by Professor Emerita ...
4 minutes ago
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PFAS exposure may alter lipid and hormone metabolism in testicular tumor cells
Cancer Center at Illinois (CCIL) members Ratnakar Singh and Michael Spinella collaborated in new research that fills in critical gaps of understanding in the relationship between testicular cancer growth and the presence ...
1 hour ago
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Pancreatic cancer may begin hiding from the immune system earlier than we thought
A new study from researchers at the Hebrew University of Jerusalem provides fresh insight into how pancreatic cancer may begin taking shape years before it is clinically detected. The research shows that early precancerous ...
8 hours ago
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What's the link between talcum powder and cancer?
More than 1,300 Victorians have joined a class action against Johnson & Johnson alleging its talcum powder products left them with ovarian cancer, mesothelioma (cancer affecting the lungs) and other cancers affecting the ...
2 hours ago
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A potential immunotherapy strategy for early-stage prostate cancer
Immunotherapy has been generally ineffective for prostate cancer because the tumors are considered immunologically "cold," meaning they do not attract enough immune cells to mount a strong attack. Hormone therapy commonly ...
16 hours ago
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Study reveals genetic balancing act between autoimmunity and cancer risk
An autoimmune disorder that affects the thyroid gland, called autoimmune hypothyroidism (AIHT), is the most common autoimmune disease, yet it remains largely understudied. New research from scientists at Broad Institute, ...
18 hours ago
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More sensitive HIT cell therapy shows promise against solid cancers
CAR T cell therapy has revolutionized the treatment of many blood cancers, but has shown little success against solid tumors, which account for over 85% of all cancers. Columbia researchers have now found that a new type ...
21 hours ago
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Jumping 'DNA parasites' linked to early stages of tumor formation
A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome. Unstable genomes are a fertile playground for cancer evolution, giving malignant ...
22 hours ago
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CRISPR-based platform pinpoints drivers of leukemia in patient cells
A new CRISPR-based tool that is directly used on patients' cancer cells can identify genes and regulatory elements driving acute myeloid leukemia (AML), an aggressive blood cancer affecting the bone marrow and blood. This ...
22 hours ago
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Largest study of vegetarian diets and cancer shows lower risk of five cancers
The largest ever study of non-meat diets and cancer risk has found that vegetarian diets are associated with lower risks of several cancers—breast, prostate, kidney and pancreatic cancers, and multiple myeloma—but a higher ...
16 hours ago
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Hormone therapy may not benefit most men receiving radiotherapy after prostate surgery, study finds
A new study led by UCLA Health Jonsson Comprehensive Cancer Center investigators suggests that adding hormone therapy to postoperative radiotherapy may provide little survival benefit for most men with prostate cancer, especially ...
18 hours ago
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A promising new drug for an invasive type of breast cancer
EPFL researchers have developed preclinical models for invasive lobular carcinoma and trialed a new drug. It slows tumor growth effectively by targeting specific features of the disease and opening the door to future clinical ...
23 hours ago
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Financial strain of cancer treatment undermines hope and life satisfaction new study finds
Cancer treatment can take a profound financial toll, and new research shows the damage does not stop at the bank account. Nearly half of patients experience significant "financial toxicity," and that strain quietly chips ...
23 hours ago
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Hypertension treatment linked to lower mortality for patients with metastatic breast cancer
Women with metastatic breast cancer often face multiple chronic conditions, and high blood pressure is among the most common. Nearly half of women in this study population had hypertension at diagnosis, with even higher rates ...
18 hours ago
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There is more than one way for triple-negative breast cancer to become resistant to therapy
About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy. When resistance arises, tumors are more likely to come back after the original treatment, significantly reducing the chances of survival. ...
18 hours ago
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A-fib occurs frequently in patients with multiple myeloma undergoing stem cell transplant
Among patients with multiple myeloma (MM) undergoing autologous stem cell transplantation (ASCT), atrial fibrillation (AF) is a frequent and high-risk complication, according to a study published online Feb. 17 in JACC: CardioOncology.
21 hours ago
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Engineered liver scaffolds reveal how colorectal cancer hides and goes dormant
Colorectal liver metastases (CRLM), cancer that has spread from the colon or rectum to the liver, have a deadly reputation. Due to its pervasive spread, typical cancer treatments like chemotherapy and surgical resection often ...
23 hours ago
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Paradigm shift in immune checkpoint biology
A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, providing new mechanistic ...
23 hours ago
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Starving cancer: The effects of nutrient deprivation on synovial sarcoma
Synovial sarcoma is an aggressive malignant tumor that primarily affects the limbs of teenagers and young adults. While it can be cured if completely removed by surgery, recurrence or metastasis, the spread of cancer to organs ...
23 hours ago
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Developing personalized vaccines for cancer via machine learning
Yale researchers have developed a machine learning model, called Immunostruct, that can help scientists create more personalized vaccines, including vaccines for cancer. They described the tool in Nature Machine Intelligence ...
Feb 26, 2026
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Fifteen-year results from clinical trial suggest that follicular lymphoma is curable
Unlike some other forms of lymphoma, advanced stage follicular lymphoma is considered incurable. But a new analysis of long-term data on patients treated for the disease years ago with standard regimens of immunotherapy and ...
Feb 26, 2026
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Laser heat therapy plus immunotherapy may dramatically improve survival for those with deadly brain cancer
High-grade astrocytoma, which includes glioblastoma, is a fast-growing, aggressive brain cancer that often returns after the tumor is removed, making it difficult to treat. Patients with recurrent high-grade astrocytoma typically ...
Feb 26, 2026
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Science for living: Can using AI risk prediction in breast cancer screening improve early detection?
Artificial intelligence is transforming medicine, but what does that mean for breast cancer screening? Researchers at UMass Chan Medical School are exploring how an AI-based tool might help identify women at higher risk for ...
Feb 26, 2026
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Clues in the bloodstream reveal the role androgen receptor alterations play in metastatic prostate cancer
A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to poorer outcomes across ...
Feb 26, 2026
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Study shows exercise during chemotherapy for breast cancer measurably improves quality of life
For many women with breast cancer, the very treatment that saves their lives can also bring fatigue, loss of muscle mass, emotional strain and other daunting obstacles. A new study shows that exercise during chemotherapy ...
Feb 26, 2026
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