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Oncology news
Combination treatment may slow disease progression in advanced sarcoma
An oral combination treatment may prevent the progression of advanced leiomyosarcoma, one of the most common subtypes of soft tissue sarcoma, according to a recent study published in The Lancet Oncology. "These findings support ...
3 hours ago
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Growth of spreading pancreatic cancer is fueled by 'underappreciated' epigenetic changes, shows study
In a lab-grown cell study focused on potential new treatment targets for halting the spread of most pancreatic cancers, Johns Hopkins Medicine scientists report they have found that a gene called KLF5 (Krueppel-like factor ...
2 hours ago
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Discovery of unique brain tumor subtypes offers hope for targeted glioma therapies
Researchers have uncovered the mechanisms behind three unique subtypes of mismatch repair deficient high-grade gliomas. The findings provide a clearer understanding of how these tumors develop, explain why patients respond ...
3 hours ago
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Ovarian cancer cells surprise scientists—the body's own defense may be the key to longer survival
A new study sheds light on why some patients with the most aggressive form of ovarian cancer respond better to treatment than others. Tumors positive for a molecule called MHC class II are linked to stronger immune responses ...
4 hours ago
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mRNA therapy could protect patients from radiation-induced skin damage caused by cancer treatment
Radiation therapy is highly effective at killing cancer cells, but it often harms healthy skin around the treatment area, a common side effect experienced by up to 95% of cancer patients undergoing treatment. In worst-case ...
3 hours ago
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Adult survivors of childhood cancer may be at higher risk for meningiomas
Certain chemotherapies are associated with an increased long-term risk of subsequent tumors in survivors of childhood cancer, according to a study led by researchers at UT Southwestern Medical Center. The findings, published ...
3 hours ago
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Genetic link to Barrett's esophagus discovered, offering new hope for esophageal cancer patients
Case Western Reserve University researchers have made a significant breakthrough in understanding Barrett's esophagus, a precancerous condition that dramatically increases the risk of developing esophageal adenocarcinoma, ...
3 hours ago
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Immunity against common virus leveraged against pancreatic cancer
Researchers at the University of California San Diego have discovered a promising new treatment approach for pancreatic cancer, one of the deadliest and most treatment-resistant forms of cancer. The approach leverages the ...
5 hours ago
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Investigating the use of a common vitamin to treat the aggressive brain cancer glioblastoma
Edward (Ed) Waldner had no idea why he didn't feel well, but he knew he didn't feel like himself. At 55 years of age, he felt exhausted all the time. It didn't seem to matter how hard he had worked that day. He wondered if ...
2 hours ago
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Researchers develop a new model to study colorectal cancer
Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients. ...
3 hours ago
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Global study marks major treatment advance for tough-to-treat high-risk blood cancer
Results from a new clinical trial led by Wake Forest University School of Medicine and Atrium Health Levine Cancer show that a new therapy could provide significantly better outcomes for patients with high-risk essential ...
7 hours ago
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New artificial intelligence tool may help personalize ovarian cancer treatment from day one
Researchers from the University of Minnesota Medical School, in collaboration with Emory University and the Georgia Institute of Technology, have developed a new artificial intelligence (AI) biomarker tool that may help predict ...
5 hours ago
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Denosumab discontinuation in non-metastatic breast cancer treated with AI raises vertebral fracture risk
Aromatase inhibitors (AIs) are a cornerstone of adjuvant therapy for hormone receptor–positive breast cancer, significantly reducing recurrence and mortality. However, by suppressing estrogen production, AIs accelerate ...
8 hours ago
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How lung tumors use the brain to avoid immune attacks
University of Pennsylvania Perelman School of Medicine and Yale University School of Medicine, along with other collaborators, report that lung adenocarcinoma can engage nerve pathways that link the lung to the brainstem ...
Research helps drive FDA label update for primary CNS lymphoma
Dana-Farber Cancer Institute-led research helped drive an FDA label update for axicabtagene ciloleucel (Yescarta) that removes a prior exclusion for patients with primary central nervous system lymphoma, a rare and aggressive ...
23 hours ago
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Physical pressure on the brain can trigger neurons' self-destruction programming
To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord. This intricate communication network is built of billions of neurons connected by synapses and managed and modified ...
Feb 9, 2026
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Itaconate identified as a new target for pediatric brain tumors called ependymomas
Ependymomas are tumors that grow in the brain or spinal cord and are the third-most common type of brain tumor in children. This type of cancer affects about 250 children in the United States each year and is most often diagnosed ...
Feb 9, 2026
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Clinical trial explores whether a genetic test can improve early detection of prostate cancer
A genetic test developed by researchers at Broad Clinical Labs and the U.S. Department of Veterans Affairs (VA) is now enabling a large, nationwide clinical trial aimed at improving health care for men at increased risk of ...
Feb 9, 2026
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The nervous system plays an active role in pancreatic cancer development, researchers discover
Notoriously tricky to detect, pancreatic cancer also often resists traditional therapy. So, researchers are urgently looking for new ways to disrupt tumor formation. Though scientists know that the nervous system can help ...
Feb 9, 2026
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Eye cancer genes predetermine liver metastasis, study finds
Cells from cancerous tumors can spread, or metastasize, throughout the body. Researchers have long sought to understand what determines where those cells will go and thrive in order to more effectively treat the cancer and ...
Feb 9, 2026
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New registry analysis links three-year childhood cancer survival to stage at diagnosis
A major study by UCL and Fondazione IRCCS Istituto Nazionale dei Tumori in Milan (INT) researchers has for the first time shown in detail how far children's cancer has spread at diagnosis in a way that can be compared between ...
Feb 9, 2026
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First in-human study finds novel immune cell therapy is safe and effective in advanced lymphoma
In a first-in-human study, researchers at The University of Texas MD Anderson Cancer Center observed strong responses and early signs of antitumor activity in patients with difficult-to-treat non-Hodgkin lymphomas who received ...
Feb 9, 2026
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Researchers uncover lymph-to-vein shortcuts inside lymph nodes, challenging dogma
Our lymphatic system is like a big network of roots spread throughout the body. It serves as part of our immune system, transporting immune cells and filtering excess fluid (lymph) before returning it to the bloodstream. ...
Feb 9, 2026
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Q&A: Simple blood test may help identify colorectal cancer patients at higher risk for recurrence and death
A new study led by researchers at Moffitt Cancer Center found that blood-based DNA markers known as protein epiScores can help predict which colorectal cancer patients face a higher risk of cancer recurrence or death. Results ...
Feb 9, 2026
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Preclinical study finds senolytics clear up to 70% of 'zombie' cells
Senolytics—a class of drugs that reduce chronic inflammation and tissue damage in aging cells—are shown to eliminate 30% to 70% of "zombie" cells in the body. These zombie cells, known as senescent cells, stop dividing ...
Feb 9, 2026
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