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Oncology news
A single enzyme keeps neuroblastoma alive—how to shut it off
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into adrenal tissue or sympathetic ganglia take a wrong turn, and a child is born harboring a malignancy that may ...
7 hours ago
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Second primary invasive melanoma rate in Queensland reaches plateau after decades-long rise
A study among more than 100,000 Queensland residents has revealed that while the incidence of developing second primary invasive cutaneous melanomas increased from the 1980s through the early 2000s, the rising trend has now ...
8 hours ago
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New mouse model of virus-driven liver cancer may boost diagnosis and treatments
Liver cancer is one of the world's deadliest cancers, and most cases are linked to chronic viral hepatitis. Yet scientists have lacked an animal model that faithfully recapitulates how the disease unfolds in people, from ...
14 hours ago
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Detecting multiple cancers and other diseases from a single blood sample
UCLA scientists have developed a simple and cost-effective blood test that, in early studies, shows promise in detecting multiple cancers, various liver conditions and organ abnormalities simultaneously by analyzing DNA fragments ...
17 hours ago
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New therapeutic target identified for neuroendocrine tumors in the gastrointestinal tract
Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells. They're scattered throughout the body, including the stomach, intestines, pancreas and lungs. Tumors that arise from these ...
16 hours ago
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Scientists target key protein duo driving colon, liver cancer
Cedars-Sinai Health Sciences University investigators have identified a drug-like compound that prevents two proteins from working together to promote the growth of colorectal and liver cancer. Findings from the preclinical ...
14 hours ago
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Sun safety ad balancing visuals and messaging gets young people to listen
Research behind the skin cancer prevention campaign "If You Could See UV" has found that evoking fear of ultraviolet (UV) radiation exposure—through a visually striking metaphor—helped motivate young adults to protect their ...
11 hours ago
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About 80% of breast cancer biopsies turn out benign. New imaging tool promises clearer diagnoses and fewer biopsies
Ultrasound is widely used in breast cancer diagnosis. While it can effectively show that a lump is filled with fluid—indicating it is unlikely to be cancer—it cannot reliably determine whether a solid mass is benign or cancerous. ...
18 hours ago
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Electroacupuncture may ease 'brain fog' in breast cancer survivors, small trial finds
Researchers at the University of California, Irvine have found that electroacupuncture may help improve cognitive function and reduce psychological distress among breast cancer survivors experiencing persistent neuropsychiatric ...
19 hours ago
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Data platform unifies blood cancer 'omics' and clinical data to accelerate discovery
Scientists at St. Jude Children's Research Hospital, the American Society for Hematology (ASH) and the Munich Leukemia Laboratory have developed a data-sharing platform that unites genomics, gene expression and clinical information ...
17 hours ago
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Examining evolving trends in oral cavity cancer among younger adults
April marks Head and Neck Cancer Awareness Month, a national campaign encouraging early detection and raising awareness of cancers affecting the mouth, throat, and related structures. This crucial message about early detection ...
19 hours ago
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Precision oncology success: Individualized multi-drug therapy outperforms standard care
A new article in the News and Perspectives section of the Journal of Medical Internet Research showcases the transformative potential of precision oncology. The article, "Further Promise and Potential for Precision Medicine ...
22 hours ago
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Diabetes drug metformin may echo the benefits of exercise in prostate cancer care
A new study has found that metformin, a widely prescribed diabetes drug, may mimic one of exercise's core biological effects in men with prostate cancer, raising levels of a molecule tied to energy balance and weight control ...
Apr 6, 2026
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Rates of secondary blood-related cancers that develop due to chemotherapy or radiation may be rising
Some therapies used to treat cancer may increase the risk of later developing cancers that affect the blood. A population-based study in Japan has revealed a gradual increase in the rates of therapy-related acute myeloid ...
Apr 6, 2026
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New AI tool predicts whether aggressive small cell lung cancer will respond to treatment
Results of a new study conclude that a pathology tool powered by artificial intelligence can predict whether a patient with extensive-stage small cell lung cancer will respond to platinum-based chemotherapy—before treatment ...
Apr 5, 2026
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Cellular pathways that drive precancerous lesions to form pancreatic tumors identified
Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate. It begins with a reversible state called acinar-to-ductal metaplasia, where cells can heal after injury ...
Apr 3, 2026
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Childhood cancer is a substantial contributor to global childhood mortality and global cancer burden
Childhood cancer is the eighth-leading cause of childhood death globally and causes more deaths than measles, tuberculosis and HIV/AIDS, with outcomes largely determined by resource availability, according to the latest findings ...
Apr 3, 2026
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Mechanisms behind tumor suppressor BAP1 highlight new treatment strategies for aggressive cancers
A team of scientists led by the National Cancer Center Singapore (NCCS) and Duke-NUS Medical School (Duke-NUS) has found a new approach for treating some of the world's most aggressive cancers associated with BAP1 mutations. ...
Apr 2, 2026
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Biomarker test may improve risk assessment for HPV-related throat cancer
Researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) are advancing the understanding of a promising blood test that could ...
Apr 2, 2026
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A redesigned endoscope offers a new way to look for early signs of ovarian cancer
Ovarian cancer remains the deadliest gynecologic cancer, largely because it is rarely found early. Symptoms are often vague, and existing screening approaches—such as blood tests and transvaginal ultrasound—can miss the disease ...
Apr 2, 2026
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Leukemia study restores silenced gene in mice. Could it point to new treatments for humans?
A key cancer-fighting gene in leukemia is switched off—not broken—and scientists from The Jackson Laboratory (JAX) have found a way to switch it back on. In a study published in Science Translational Medicine, the team reveals ...
Apr 2, 2026
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Could one protein play both sides? How Stard7 shifts colon cancer in different models
Alain Chariot's team has just published a study in EMBO Molecular Medicine shedding light on the unexpected role of the Stard7 protein in the development of intestinal cancers. Long regarded as a simple lipid transporter, ...
Apr 2, 2026
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How pancreatic tumors thwart an iron-driven demise
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal adenocarcinomas (PDACs) harbor ...
Apr 2, 2026
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Reprogramming 'gatekeeper' immune cell may boost cancer immunotherapy
St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their energy production can ...
Apr 2, 2026
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Innovative targeted therapy halts prostate cancer spread to the bone
New findings from VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM), published in Pharmacological Research, show that an innovative drug effectively prevents prostate tumors from spreading ...
Apr 2, 2026
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