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Oncology & Cancer news
Oncology & Cancer
HER2-targeted radioimmunotherapy regimen achieves complete and durable response in breast cancer model
A new radioimmunotherapy approach has the potential to cure human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to new research published in the November issue of The Journal of Nuclear Medicine. ...
49 minutes ago
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How colorectal cancer evades immunotherapy using a dual barrier
Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies—treatments that reactivate the immune system to attack tumor cells—have transformed the treatment of many types ...
13 hours ago
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Combination immunotherapy helps overcome melanoma treatment resistance
Early data from a Phase 2 clinical trial show a combination of immunotherapy medications can activate a robust immune response and help overcome treatment resistance in patients with refractory melanoma.
4 hours ago
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Bioengineered bone marrow model successfully used in leukemia research
Scientists at the University of Glasgow have successfully used the first bioengineered bone marrow model to carry out vital cancer research, offering new insights into potential therapies for the disease.
14 hours ago
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Lung cancer's earliest stages may be driven by inflammation
By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The University of Texas MD Anderson Cancer Center have discovered that the earliest stages of lung ...
Nov 6, 2025
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Combination therapy for pancreatic cancer offers new treatment approach
Pancreatic cancer, also known as pancreatic ductal adenocarcinoma, is one of the most aggressive types of cancer. Despite advances in modern medicine, survival rates remain very low, and many patients develop resistance to ...
Nov 6, 2025
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Breast cancer relapse: Key cellular resistance mechanism discovered
Triple-negative breast cancer is one of the most aggressive and difficult cancers to treat. It can initially respond well to therapeutic combinations of chemotherapy, but a tiny minority of tumor cells may manage to tolerate ...
Nov 6, 2025
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Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer
Aerobic and resistance exercise can significantly improve physical performance in patients living with metastatic breast cancer, according to new results presented at the Advanced Breast Cancer Eighth International Consensus ...
Nov 6, 2025
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Transforming cancer treatment with ultrasound
Chemotherapy has long been a cornerstone of cancer treatment, but its effectiveness comes at a cost. The powerful drugs used to kill cancer cells often damage healthy tissues as well, leading to side effects ranging from ...
Nov 6, 2025
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Common heartburn and blood pressure medicines linked to adverse breast cancer outcomes in large global study
A major international study involving 23,000 people has found concerning evidence about the impact of a range of common, everyday medications on the treatment outcomes for patients with breast cancer.
Nov 6, 2025
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Q&A: Managing menopause after cancer
Menopause can bring a wave of physical and emotional changes—and for people with cancer, those changes can start earlier or feel more intense. Treatments like chemotherapy, radiation, surgery, and/or endocrine therapy can ...
Nov 6, 2025
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Combination treatment may help cut lifelong ibrutinib for chronic lymphocytic leukemia patients
Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia in the Western Hemisphere, affecting approximately 200,000 people in the United States.
Nov 6, 2025
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Bowel cancer's 'Big bang': How a crucial moment determines future growth
Like the astronomical explosion that kickstarted the universe, bowel cancer has a "Big Bang" moment which determines how it will grow, according to new research.
Nov 5, 2025
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Macrophage 'bodyguard' disruptors may help overcome hormone-resistant breast cancer
In preclinical studies, researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have tested a new combination therapy for hormone-resistant, estrogen receptor-positive ...
Nov 5, 2025
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Experimental drug blocks key protein to trigger cancer cell self-destruction in lung tumors
NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.
Nov 5, 2025
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Triggering cell death in metastatic melanoma may pave the way for new cancer treatments
Metastatic melanoma cells that have spread to lymph nodes survive by relying on a protein called ferroptosis suppressor protein 1 (FSP1)—a surprising metabolic dependency that could open the door to a new class of cancer ...
Nov 5, 2025
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Why cancer immunotherapy isn't effective for everyone
A study led by André Veillette, a researcher at the Montreal Clinical Research Institute (IRCM) and a professor in the Faculty of Medicine at University of Montreal, sheds new light on the complexity of the immune system ...
Nov 5, 2025
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CRISPR screen identifies new regulator of androgen receptor in prostate cancer
A poorly characterized protein, historically thought to be a chaperon or enzyme, may actually be a key player in prostate cancer. In a systematic CRISPR screen, scientists from Arc Institute, UCSF, and the Fred Hutchinson ...
Nov 5, 2025
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Existing drug could reduce breast cancer risk in pre-menopausal women
A University of Manchester study reveals a drug approved for use in other conditions could be repurposed as a preventive breast cancer treatment in women before menopause.
Nov 5, 2025
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Radiotherapy after mastectomy can be avoided, study finds
Radiotherapy can be safely omitted as a treatment for many breast cancer patients who have had a mastectomy and are taking anti-cancer drugs, a study shows.
Nov 5, 2025
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Certain p53 mutations may make tumors more vulnerable to immunotherapy
The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to cancer. But when p53 ...
Nov 5, 2025
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Data-driven risk stratification guides childhood brain tumor treatment, reducing side effects
By analyzing data from three clinical trials treating children with the brain tumor medulloblastoma, scientists at St. Jude Children's Research Hospital have designed an approach to safely reduce therapy, thereby lowering ...
Nov 5, 2025
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Advanced breast cancer patients living longer thanks to improvements in treatment and care
People diagnosed with advanced breast cancer in 2025 can expect to live for an extra six or seven months, compared to the average survival time for patients diagnosed in 2011, according to a major study of patient data in ...
Nov 5, 2025
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Global survey highlights challenges faced by young women with advanced breast cancer
Nearly half of all women aged younger than 40 who live with advanced breast cancer have children under the age of 18, according to the first global survey to investigate the challenges these women face. Results from the survey ...
Nov 5, 2025
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