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Oncology news
Cellular pathways that drive precancerous lesions to form pancreatic tumors identified
Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate. It begins with a reversible state called acinar-to-ductal metaplasia, where cells can heal after injury ...
Apr 3, 2026
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Childhood cancer is a substantial contributor to global childhood mortality and global cancer burden
Childhood cancer is the eighth-leading cause of childhood death globally and causes more deaths than measles, tuberculosis and HIV/AIDS, with outcomes largely determined by resource availability, according to the latest findings ...
Apr 3, 2026
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Mechanisms behind tumor suppressor BAP1 highlight new treatment strategies for aggressive cancers
A team of scientists led by the National Cancer Center Singapore (NCCS) and Duke-NUS Medical School (Duke-NUS) has found a new approach for treating some of the world's most aggressive cancers associated with BAP1 mutations. ...
Apr 2, 2026
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Biomarker test may improve risk assessment for HPV-related throat cancer
Researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) are advancing the understanding of a promising blood test that could ...
Apr 2, 2026
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A redesigned endoscope offers a new way to look for early signs of ovarian cancer
Ovarian cancer remains the deadliest gynecologic cancer, largely because it is rarely found early. Symptoms are often vague, and existing screening approaches—such as blood tests and transvaginal ultrasound—can miss the disease ...
Apr 2, 2026
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Could one protein play both sides? How Stard7 shifts colon cancer in different models
Alain Chariot's team has just published a study in EMBO Molecular Medicine shedding light on the unexpected role of the Stard7 protein in the development of intestinal cancers. Long regarded as a simple lipid transporter, ...
Apr 2, 2026
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Leukemia study restores silenced gene in mice. Could it point to new treatments for humans?
A key cancer-fighting gene in leukemia is switched off—not broken—and scientists from The Jackson Laboratory (JAX) have found a way to switch it back on. In a study published in Science Translational Medicine, the team reveals ...
Apr 2, 2026
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Reprogramming 'gatekeeper' immune cell may boost cancer immunotherapy
St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their energy production can ...
Apr 2, 2026
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How pancreatic tumors thwart an iron-driven demise
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal adenocarcinomas (PDACs) harbor ...
Apr 2, 2026
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Innovative targeted therapy halts prostate cancer spread to the bone
New findings from VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM), published in Pharmacological Research, show that an innovative drug effectively prevents prostate tumors from spreading ...
Apr 2, 2026
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Lung cancer surgery safe for many patients over 80, study finds
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have found that adults aged 80 and older with early-stage lung cancer can safely undergo surgery and achieve outcomes comparable ...
Apr 2, 2026
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The tumor microbiota: A new frontier in cancer biology
The tumor microbiota—which includes bacteria, fungi, viruses, and other microorganisms present in tumor tissue—is now considered an important component of the tumor microenvironment. An international consensus article published ...
Apr 2, 2026
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A new biomarker helps assess the aggressiveness of glioblastoma
Researchers from the Biomedical Data Science Laboratory (BDSLab) at the ITACA Institute of the Universitat Politècnica de València have developed a new method based on magnetic resonance imaging that enables objective quantification ...
Apr 2, 2026
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New research investigates cancer survivors' 'symptom burden'
A declaration of remission doesn't mean a cancer patient's illness is fully gone. Many cancer survivors face lingering symptoms that lead to both physical discomfort and mental strain. Even though there are some commonalities, ...
Apr 2, 2026
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First-in-class dual HIF inhibitors eliminate tumors in mice when combined with immunotherapy
Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, first-in-class drugs that inhibit hypoxia-inducible factors 1 and 2, a pair of transcription factors ...
Apr 2, 2026
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Radiation therapy improves outcomes for 'supermassive' bile duct tumors
A new study from researchers at The University of Texas MD Anderson Cancer Center demonstrates that a specialized high-dose type of radiation delivery may significantly improve outcomes for patients with large bile duct tumors ...
Apr 2, 2026
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Heat-activated skin patch can kill melanoma cells without surgery
Melanoma is a deadly form of skin cancer that is typically removed surgically. Now, researchers publishing in ACS Nano report they have developed a potential noninvasive treatment for melanoma in the form of a stretchy, heat-activated ...
Apr 1, 2026
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Pesticides and cancer: Study reveals the biological mechanisms behind an environmental health risk
A new study, published in Nature Health, reveals a strong link between exposure to agricultural pesticides in the environment and the risk of developing cancer. By combining environmental data, a nationwide cancer registry, ...
Apr 1, 2026
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Common metabolic enzyme could predict cancer immunotherapy benefits—and help more patients respond
Immunotherapies have transformed cancer treatment by helping the immune system recognize and attack tumors. They work for only about 20% of patients, though, and doctors still struggle to predict who will benefit.
Apr 1, 2026
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Cause or effect? Study answers question about gene linked with colorectal cancer
A new study has answered a question that has puzzled cancer researchers for decades: Does a genetic defect found in nearly all human colorectal cancers simply accompany the disease, or does it trigger its development? A team ...
Apr 1, 2026
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Dangers of 'anti-aging' supplements in cancer protection revealed
Millions of Americans take daily supplements—nicotinamide mononucleotide (NMN), nicotinamide riboside (NR) and nicotinamide (NAM)—to boost energy, slow aging and protect the heart and brain. Many cancer patients also take ...
Apr 1, 2026
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The hidden dangers of oral cancer
Oral Cancer Awareness Month is observed every April, and it highlights the urgent need for early detection. According to the American Cancer Society, oral and oropharyngeal cancers still claim about one life every hour in ...
Apr 1, 2026
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First-in-class radio-theranostic utilizes novel antibody to target B7-H3 proteins in cancer cells
Researchers from The University of Texas MD Anderson Cancer Center have developed a first-in-class antibody that targets a protein overexpressed in many cancer types, allowing for the creation of a new radio-theranostic treatment ...
Apr 1, 2026
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Robotic bronchoscopy could be safer, faster path to diagnosing lung cancer
As lung cancer screening identifies an estimated 1.6 million suspicious lung nodules each year in the U.S. alone, physicians face a challenge. Most peripheral pulmonary lesions are benign, yet the malignant minority represent ...
Apr 1, 2026
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Targeted therapy improves long-term outcomes for patients with rare mutations driving lung cancer
In some non-small cell lung cancers (NSCLCs), changes to the RET gene (known as RET fusions) can drive tumor growth. In a phase 1/2 clinical study with a 42-month-long follow-up period, researchers from Mass General Brigham ...
Apr 1, 2026
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