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Oncology news
Novel tool measures how cancer cells rewrite genetic instructions to aid growth and survival
Cancer is caused by faulty genes, but what also shapes a cancer cell's behavior is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive. A study published in ...
3 hours ago
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Unusual tumor cells may be overlooked factors in advanced breast cancer
An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, according to a study led by investigators at Weill Cornell Medicine ...
15 hours ago
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Experimental chemo drug triggers 'viral mimicry' signals that rally immune attack
In recent years, scientists have discovered that some chemotherapy drugs not only kill cancer cells directly, but at least in some patients, mysteriously also trigger their immune system to attack the cancer. That would seem ...
15 hours ago
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Severe COVID-19 and flu can facilitate lung cancer months or years later
Severe COVID-19 and influenza infections prime the lungs for cancer and can accelerate the disease's development, but vaccination heads off those harmful effects, new research from UVA Health's Beirne B. Carter Center for ...
16 hours ago
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Distinct tumor 'neighborhoods' could guide more targeted treatments in aggressive childhood brain cancer
New research published in Nature finds that tumor cells within supratentorial ependymomas (SE)—an aggressive childhood brain cancer—cluster into distinct tumor cell populations. Much like a neighborhood, each cell subtype ...
20 hours ago
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Aging may change lung cancer treatment: Targeting ATF4 could curb metastasis
Researchers at the University of Gothenburg have identified a protein linked to an increased risk of metastasis and recurrence in lung cancer. The findings are presented in a study published in the journal Nature that paves ...
14 hours ago
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New cancer therapies target epigenetic switch
Cancers emerge from many different paths. One path begins early, in embryonic development, when a protein complex called PRC2, which regulates cell differentiation, identity, and plasticity, becomes dysfunctional. PRC2 has ...
17 hours ago
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Turning cancer's protein machinery against itself to boost immunity
A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response. Researchers ...
19 hours ago
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Optical genome mapping detects additional genetic variants in nearly 20% of individuals with acute leukemia
New research assessing the efficacy of optical genome mapping (OGM) in a group of patients with acute leukemia has demonstrated that OGM provided reliable and robust analytical performance with high sensitivity and specificity ...
10 hours ago
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Breast cancer stage at diagnosis differs sharply across rural US regions
Where a woman lives significantly affects whether her breast cancer is diagnosed at an early or late stage, according to a national analysis published in the Journal of the American College of Surgeons (JACS). Researchers ...
13 hours ago
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IVF not linked to higher overall cancer rates, but study shows differences in some cancers
Women who used fertility treatments had no higher overall risk of invasive cancer than other women, a large Australian study led by researchers from UNSW Sydney has found. The study, published in JAMA Network Open, analyzed ...
Mar 10, 2026
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Scientists develop two-vaccine strategy to fight T cell lymphoma
T cell lymphomas are notoriously difficult to treat because immunotherapy, despite being one of the most effective therapies for treating cancer, can't easily distinguish cancerous T cells from healthy ones. Now, scientists ...
Mar 10, 2026
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Common p53 genetic mutation reveals Achilles' heel in lung cancer
A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA replication in cancer ...
Mar 10, 2026
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Google AI rivals radiologists in breast cancer detection
New research on 175,000 women—the largest NHS study to date—on the use of AI in breast cancer screening shows that AI detected more cases of invasive cancer, more cases overall, had fewer false positives, and recalled ...
Mar 10, 2026
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Study identifies gene linked to chemotherapy resistance in prostate cancer
A gene called FOXJ1 may drive resistance to taxane chemotherapy during treatment for advanced prostate cancer, according to a new study led by investigators at Weill Cornell Medicine and Beth Israel Deaconess Medical Center. ...
Mar 10, 2026
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Why 'being squeezed' helps breast cancer cells to thrive
A new study led by researchers at Adelaide University and published in Science Advances reveals why some cancers can grow and survive in the body, while others cannot. It turns out that intense mechanical pressure experienced ...
Mar 10, 2026
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Nanohydrogels steer cancer drugs to tumors, aiming to spare healthy tissue
Exhaustion creeps in. Appetite vanishes. Hair thins. The person in the mirror looks gaunt. It's the paradox of cancer treatment: The same drugs meant to save a life can also wear the body down. Nick Housley, assistant professor ...
Mar 10, 2026
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AI boosts breast cancer detection by 10.4% in UK screening evaluation
The UK's first comprehensive evaluation of the use of Artificial Intelligence (AI) in breast cancer screening found that it can increase breast cancer detection by 10.4% and has the potential to reduce the workload of health ...
Mar 10, 2026
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Clotting protein presents a potential target in pancreatic cancer
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that depleting a clotting protein made by the liver could slow down pancreatic cancer. The research, recently published in ...
Mar 10, 2026
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Q&A: A troubling mortality shift for late Gen Xers and early Millennials
Despite major advances in medicine, U.S. life expectancy barely budged in the 2010s, and it still lags that of other wealthy nations. Researchers have pointed to rising "deaths of despair"—drug overdoses, suicides, and ...
Mar 10, 2026
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Boron agents reach previously untreatable tumors
Boron agents termed GluBs, developed by Science Tokyo researchers, have overcome a key limitation in cancer therapy by entering tumor cells through a pathway that standard drugs cannot use. The GluBs target ASCT2, a transporter ...
Mar 10, 2026
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Targeted treatments plus engineered immune cells may slow early spread of triple‑negative breast cancer, study reveals
A new study has revealed a promising new approach to curb the spread of triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of the disease. Published recently in Cancer Letters, Gabriel ...
Mar 10, 2026
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LeaN On: Reducing risk of lymphedema after breast cancer
Living with, or being at risk of, lymphedema after breast cancer can leave many people feeling uncertain and overwhelmed. Too often, survivors must search for information on their own, sometimes too late, and without clear ...
Mar 10, 2026
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Low testosterone levels may be associated with increased risk of prostate cancer progression during surveillance
A new study led by researchers at The University of Texas MD Anderson Cancer Center found that prostate cancer patients with low testosterone levels may have a higher risk of cancer progressing to a more aggressive form while ...
Mar 10, 2026
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Alternative breast cancer treatment tied to about four times higher mortality, nationwide analysis finds
The alternative medicine industry is expanding rapidly, fueled in large part by the surge of health-related content on social media. This growing trend has become an increasing concern for oncology practitioners and patients, ...