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Oncology news
Global trial shows novel treatment for triple-negative breast cancer nearly doubles survival
A global, multicenter phase III trial, TROPION-Breast02, led by a senior medical oncologist and researcher from the National Cancer Centre Singapore, has demonstrated a significant breakthrough in improving the survival of ...
12 hours ago
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First-of-its-kind drug aims to protect the heart while increasing effectiveness of cancer treatments
A team of University of Alberta researchers has developed a cardio-oncology drug that protects the heart from chemotherapy damage while enhancing the effectiveness of cancer treatments against tumor growth and spread. In ...
16 hours ago
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Chemical NDMA is much more likely to cause cancerous mutations after early-life exposure, study suggests
A new study from MIT suggests that a carcinogen that has been found in medications and in drinking water contaminated by chemical plants may have a much more severe impact on children than adults. In a study of mice, the ...
15 hours ago
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Biological shield can prevent skin cancer cells from transforming into aggressive metastatic forms
A new study has identified a molecular guardian that keeps skin cells from forgetting what they are and transforming into aggressive, migratory killers. By stabilizing a master genetic switch, this protein shield prevents ...
18 hours ago
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This shrimp-inspired camera sees hidden cancer spread and could transform how surgeons remove lymph nodes
Researchers have developed a compact camera that captures ultraviolet, near-infrared, and visible images using a single chip. Inspired by the multiwavelength vision capability of the mantis shrimp, the camera could help surgeons ...
19 hours ago
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Liver cancer roadmap links tumor hallmarks to treatment, including targetable mutations
A new review from the Icahn School of Medicine at Mount Sinai and the Hospital Clínic de Barcelona provides one of the clearest roadmaps to date for understanding and treating liver cancer, one of the deadliest cancers worldwide. ...
12 hours ago
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First-line targeted therapy shows antitumor activity in patients with advanced lung cancer
First-line zongertinib showed antitumor activity in treatment-naive patients with advanced or metastatic HER2-mutant non-small cell lung cancer (NSCLC), providing a safe and effective oral targeted treatment alternative to ...
11 hours ago
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Colon cancer deaths in younger adults rose mainly among those without degrees, study says
The worrisome rise in colorectal cancer deaths in younger adults is concentrated in people with less education, suggesting socioeconomic factors could be driving the escalation, according to a new study.
13 hours ago
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Severe male infertility tied to higher colorectal and thyroid cancer risk
Men with severely reduced fertility are at greater risk of developing other health conditions later in life. A research team from Lund University in Sweden has now shown that these men are also more likely to develop colorectal ...
14 hours ago
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Key protein may explain why triple-negative breast cancer spreads so fast
Researchers at Ben-Gurion University of the Negev have identified a protein that plays a central role in enabling aggressive breast cancer cells to spread to other parts of the body. Triple-negative breast cancer remains ...
17 hours ago
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Sleep deprivation disrupts gut microbiota, worsening colorectal cancer outcomes
Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have made a startling discovery: The gut microbiota drives changes to the immune system caused by chronic sleep ...
13 hours ago
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Robotic or laparoscopic surgery can be successful for gallbladder cancer in select patients
Gallbladder cancer (GBC) is a rare form of cancer with no signs or symptoms in the early stages. In the U.S., approximately 2,000 people die annually from this condition, with only 20% diagnosed at an early stage. Surgery ...
12 hours ago
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Confirmed precursor to commonest form of esophageal cancer offers opportunities to catch the disease early
Scientists have found the strongest evidence to date that a condition known as Barrett's esophagus is the starting point for all cases of esophageal adenocarcinoma—the most common type of esophageal cancer in the developed ...
Apr 16, 2026
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New imaging tools help cancer researchers see inside living cells
A new study co-led by an Oregon Health & Science University researcher describes a breakthrough in microscopy tools that could dramatically expand how cancer biology labs study the inner workings of living cells. The research, ...
Apr 16, 2026
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A major cancer protein hijacks RNA editing, exposing a new weakness in prostate tumors
Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new layer of genetic regulation that could reshape how certain cancers are treated. In a new study published ...
Apr 15, 2026
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A powerful new cancer map tracks hundreds of mutations to one escape route and exposes a drug target
Diseases like cancer or neurodegeneration are known to arise from genetic misfires. But treating such complex conditions hasn't been simply a matter of identifying the malfunctioning genes involved. With hundreds of genetic ...
Apr 15, 2026
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Off-label cancer drugs deliver durable benefit for some patients in large trial
The largest published prospective evaluation of off-label targeted cancer therapies has shown that more patients could benefit from existing drugs. After including over 1,600 patients in the Dutch multicenter DRUP trial, ...
Apr 15, 2026
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Genome-wide analysis reveals host–virus genetic interactions in cancer risk
A study from Columbia University Mailman School of Public Health reports a major advance in understanding how interactions between human and viral genomes shape disease risk. The research found that variations in the Epstein–Barr ...
Apr 15, 2026
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Mitochondria keep key immune cells battle-ready by sustaining electron flow, study reveals
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular ...
Apr 15, 2026
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Blood-based DNA signals may help track osteosarcoma in children
Detecting whether osteosarcoma, a rare but aggressive bone cancer that most often affects children and adolescents, has returned or spread remains a major challenge for patients and doctors. Blood-based biomarkers, which ...
Apr 15, 2026
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A molecular movie captures cancer's great escape from targeted therapy
Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction of cancer cells become harder to kill. A new study from researchers at the Institute ...
Apr 15, 2026
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From benign growth to pancreatic cancer: New study shows how the switch gets flipped
As we age, our cells accumulate genetic changes—mutations—some of which open the door to cancer. Scientists call these mutations "oncogenic," meaning "tumor-producing." By our senior years, we each may harbor as many as 100 ...
Apr 15, 2026
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AI-powered biochip detects genetic markers in 20 minutes
A team of scientists from NTU Singapore has developed a new biochip that, when paired with artificial intelligence, can quickly and accurately detect extremely small amounts of microRNAs, which are tiny genetic markers linked ...
Apr 15, 2026
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AI tool reveals rare cancer cells tied to faster disease progression
McGill University researchers have developed an artificial intelligence tool that can identify small groups of cells most responsible for driving aggressive cancers. The tool, called SIDISH, offers scientists a clearer path ...
Apr 15, 2026
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Overloaded RNA 'editing room' reveals weakness in RAS-driven cancers
Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have identified an overworked cog in the cellular machinery of tumor cells that could be targeted by new treatment options for an aggressive ...
Apr 15, 2026
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