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Oncology news
Long non-coding RNA may be a promising therapeutic target for cancer
Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its potential as a therapeutic ...
8 hours ago
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Why anti-cancer drugs do not always live up to expectations
For more than a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations. The biology looked promising. Many cancers depend on oncogenes that "Bromo- and Extra-Terminal domain" ...
19 hours ago
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New method provides clearer view of how genome functions in cancer
Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like cancer. The findings were ...
8 hours ago
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Brain tumors: 3D experimental system to evaluate candidate drugs against glioma
Glioma is a tumor of the central nervous system that originates from glial cells, which support neurons in the brain. In the less aggressive, slow-progressing forms, gliomas are often found in children and youth. Glial tumors ...
10 hours ago
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AI outperforms doctors at summarizing complex cancer pathology reports
AI models can generate more complete summaries of complex cancer pathology reports than physicians, according to a new Northwestern Medicine study that tested six models developed by Meta, Google, DeepSeek and Mistral AI.
17 hours ago
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New tool offers personalized approach to blood cancer care
Researchers have developed a new tool to help clinicians tailor personalized treatment plans for patients with a rare blood cancer called chronic myelomonocytic leukemia (CMML). The tool, called the international CMML Prognostic ...
14 hours ago
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Cancer risk is significantly higher for adults who have never married, finds large study
Adults who have never been married face a significantly higher risk of developing cancer than those who have been married, according to a large U.S. study of more than four million cases. The increased risk spans nearly every ...
Apr 8, 2026
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Extra chromosomes may seed childhood leukemia years before disease, study suggests
B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the presence of cells with an excess of chromosomes ...
Apr 8, 2026
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A urine test that could change the course of bladder cancer care
Bladder cancer arises from the lining of the bladder, the organ that stores urine, and is one of the most common cancers in the United States. Most patients are diagnosed at an early stage called non-muscle invasive bladder ...
Apr 8, 2026
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Sequencing method exposes hidden gaps in immune signaling by tracking RNA and protein together
A new single-cell technology is giving scientists their clearest view yet of immune cell behavior—capturing not just genetic intent, but real-time activity. By measuring RNA and proteins simultaneously, it reveals cytokine ...
Apr 8, 2026
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Antibody drugs with strong immune cell binding linked to allergic reactions
Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory ...
Apr 8, 2026
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Blocking RNA 'cleanup' may expose hidden cancer antigens, boosting immunotherapy
A new method of making cancer cells more visible to the immune system could improve how well immunotherapy works against a range of different tumors, potentially leading to more effective treatment for patients, according ...
Apr 8, 2026
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Researchers find new target to sensitize pancreatic tumors to immunotherapy
Researchers at The University of Texas MD Anderson Cancer Center have identified an epigenetic target for replication stress, called DPY30, that could sensitize pancreatic tumors to immunotherapy and serve as a predictive ...
Apr 8, 2026
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Novel strategy enables protection against radiation therapy resistance in lung cancer
In a preclinical study published in Cancer Research, researchers from the University of Texas MD Anderson Cancer Center have identified one way that lung cancer becomes resistant to radiation therapy and then developed a ...
Apr 8, 2026
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Scientists reveal a new way cancer cells survive DNA damage
A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized. Scientists at Scripps Research have discovered that the enzyme Pol theta ...
Apr 7, 2026
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Smart MRI molecules developed to detect and treat cancer
Researchers at NYU Abu Dhabi have developed smart molecules that can both detect and treat cancer, offering a safer and more precise approach to care. The research, published in the Journal of the American Chemical Society, ...
Apr 7, 2026
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Treating tumors independently of oxygen: Photodynamic therapy uses hydrogen peroxide instead
Photodynamic treatment of cancer is based on administering an initially inactive substance that is only activated in the tumor via targeted light irradiation. It then generates reactive oxygen species that kill the cancer ...
Apr 7, 2026
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A new AI model could help doctors detect lung cancer earlier
Lung cancer remains the leading cause of cancer-related deaths worldwide, accounting for nearly one in five cancer deaths—around 1.8 million lives lost each year. One of the main reasons is late diagnosis: in its early stages, ...
Apr 7, 2026
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A single enzyme keeps neuroblastoma alive—how to shut it off
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into adrenal tissue or sympathetic ganglia take a wrong turn, and a child is born harboring a malignancy that may ...
Apr 7, 2026
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'Hamelin Assay' traces molecular mechanisms that may guide cancer cell spread
Metastases are a key problem in many types of cancer. As descendants of the primary tumor, they can grow in other organs distant from the primary site and are often difficult to identify. A research team from the Institute ...
Apr 7, 2026
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Blood-based biomarker could help stratify cancer risk in Lynch Syndrome
Researchers at The University of Texas MD Anderson Cancer Center have discovered a new blood-based biomarker that can help identify and characterize asymptomatic people with Lynch Syndrome (LS) who are more susceptible to ...
Apr 7, 2026
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Scientists uncover previously unknown chromatin regulation mechanism with therapeutic potential for pediatric cancer
As many as 1 in 4 cancers are driven by mutations in the SWI/SNF chromatin-remodeling complex, which controls access to DNA. A study led by St. Jude Children's Research Hospital recently identified the gene-regulatory protein ...
Apr 7, 2026
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HRT patches to treat prostate cancer—here's how it works
Women's HRT patches can treat prostate cancer just as effectively as standard hormone injections—but with fewer of the worst side effects—according to a large UK trial published in the New England Journal of Medicine. The ...
Apr 7, 2026
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Treating previously untreatable cancers: How CAR‑T cell therapy could be made accessible to more patients
Cancers that were once considered incurable now have new treatment options. Among these innovations are CAR-T (chimeric antigen receptor T cell) therapies that modify a patient's T cells, which play an important role in immune ...
Apr 7, 2026
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