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Oncology news

Could gene edits solve obstacles to treatment for the most common types of cancer?

Since 2017, a personalized immunotherapy called Chimeric Antigen Receptor, or CAR-T cell treatment, has worked wonders to treat patients with blood cancers such as leukemia. But when it comes to treating solid tumor cancers, ...

Leukemia cells use a sugar-coated protein to hide from the immune system, study reveals

Leukemia is adept at dodging the immune system, making it resistant to many of the newest generation of cancer immunotherapies. Now, researchers have identified a key part of the cancer's disguise: a protein called CD43 on ...

How an overactive immune system can drive cancer

The immune system is designed to protect us against viruses and bacteria. In autoimmune diseases, however, the immune system instead attacks the body's own cells. Conditions such as systemic lupus erythematosus (lupus) and ...

Why anti-cancer drugs do not always live up to expectations

For more than a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations. The biology looked promising. Many cancers depend on oncogenes that "Bromo- and Extra-Terminal domain" ...

New tool offers personalized approach to blood cancer care

Researchers have developed a new tool to help clinicians tailor personalized treatment plans for patients with a rare blood cancer called chronic myelomonocytic leukemia (CMML). The tool, called the international CMML Prognostic ...

Scientists reveal a new way cancer cells survive DNA damage

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized. Scientists at Scripps Research have discovered that the enzyme Pol theta ...

Smart MRI molecules developed to detect and treat cancer

Researchers at NYU Abu Dhabi have developed smart molecules that can both detect and treat cancer, offering a safer and more precise approach to care. The research, published in the Journal of the American Chemical Society, ...