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Oncology news
Common deworming drug helps restore lung cancer's sensitivity to targeted therapy in mice
A form of lung cancer, which is found in about 10%–15% of Western patients and 40%–50% of Asian patients, is driven by a mutation in the epidermal growth factor receptor (EGFR) gene. Gefitinib is a go-to drug that shuts down ...
6 hours ago
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Reversible genetic switches could give cancer immunotherapy more precise control
A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute ...
5 hours ago
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How RNA molecules influence the development of aggressive leukemia
Researchers at the University of Veterinary Medicine Vienna, in collaboration with the CeMM Research Center for Molecular Medicine and St. Anna Children's Cancer Research, have developed a new analytical method that reveals ...
2 hours ago
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Common leukemia mutation derails protein positioning during cell division, study reveals
Experts from the University of Nottingham have discovered how a common genetic mutation disrupts the positioning of a key protein during cell division, revealing a new mechanism behind acute myeloid leukemia and a potential ...
3 hours ago
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What happens when brain tumors return? International study tracks genetic changes behind recurring cancers
When patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns. Among those are IDH-mutant gliomas, a group of brain tumors that invariably recur despite ...
4 hours ago
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Mixed beam measurement method could help make ion cancer therapy more precise
In ion beam therapy, atomic nuclei are accelerated to high energies in a particle accelerator, for example, a synchrotron, and precisely directed at a tumor. There, they damage cancer cells and destroy tumor tissue. This ...
2 hours ago
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Insights about cachexia, one of cancer's most common complications, hiding in routine patient data
Cancer cachexia has long been one of oncology's most stubborn unsolved problems. This severe, uncontrollable wasting affects roughly half of all cancer patients. It makes treatment harder to tolerate, erodes a person's quality ...
4 hours ago
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Trapping cancer-driving DNA rings outside cell nucleus silences their genes, researchers find
Cells from rapidly growing, highly metastatic tumors often contain numerous rings of extrachromosomal DNA (ecDNA). This circular DNA frequently carries oncogenes—genes that promote cancer. Researchers have long sought vulnerabilities ...
8 hours ago
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Cancer-promoting protein also helps engineered immune cells fight tumors in lab tests
Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.
4 hours ago
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Cancer-linked protein needs a partner to activate silent DNA, fruit fly experiments reveal
In Ewing sarcoma, an abnormal protein formed by the fusion of two genes can activate repetitive DNA regions that normally remain silenced and turn them into gene regulatory elements. This mechanism contributes significantly ...
5 hours ago
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Ovaries remain active decades after menopause, study reveals
Contrary to popular belief, the postmenopausal ovary is not defunct. In a new study of ovaries from 28 women, scientists at Northwestern University and the Buck Institute for Research on Aging found that in the decades well ...
20 hours ago
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Neighborhood conditions linked to childhood cancer survivors' long-term health
Survivors of childhood cancer can make lifestyle changes to reduce later-in-life chronic health conditions, such as diabetes and heart disease. Still, some survivors report local environmental barriers to taking these actions. ...
4 hours ago
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Abnormal antibodies that disrupt DNA repair could explain childhood cancer
A team of scientists in Norway has found evidence for a new mechanism for the development of cancer in children: They seem to produce an unusual amount of aberrant antibodies against the building blocks that make up the DNA ...
21 hours ago
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Pope Leo XIV's lung cancer highlights growing number of nonsmokers diagnosed with the disease—and younger people too
When many people think of an average lung cancer patient, they often imagine an older man smoking. But the face of lung cancer has changed. Over the past 15 years, more women, never-smokers and younger people have been diagnosed ...
8 hours ago
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Jawbone necrosis in advanced breast cancer: Study highlights the importance of oral health
Antiresorptive drugs, which reduce bone breakdown, are an important part of treatment for breast cancer that has spread to the bones. However, their use can be associated with medication-related osteonecrosis of the jaw (MRONJ), ...
11 hours ago
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Expanded genetic testing and early transplant referrals anchor new myelofibrosis care recommendations
The American Society of Hematology (ASH) has released guidelines on the management of myelofibrosis, a rare and life-threatening blood cancer. The new guidelines recommend expanded molecular testing, early transplant referral, ...
10 hours ago
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Continuously evolving cells help pancreatic cancer evade treatment and spread
An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment for one of the deadliest forms of cancer.
Oct 13, 2026
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Scientists identify clues to making immunotherapy more effective against glioblastoma
Two new studies led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center provide new insight into how the immune system can successfully be activated against glioblastoma while revealing why these therapies ...
Oct 13, 2026
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AI tool reveals what attracts immune cells to tumors and what keeps them away
Researchers at The University of Texas MD Anderson Cancer Center and collaborating institutions in Texas developed an artificial intelligence (AI) model that helps explain how immune cells find their way to specific locations ...
Oct 13, 2026
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Enhanced CAR T-cell therapy shows early promise for B-cell cancers in first-in-human trial
Results from a Phase I clinical trial led by The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) show a possible way to improve therapy ...
Oct 13, 2026
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How a common virus's hijack of cell repair processes may promote cancer
Most people will become infected with Epstein-Barr virus, or EBV, at some point in their lives. In addition to being a common herpesvirus, EBV persists in its host for life as a "quiet" or latent infection. While EBV infection ...
Oct 13, 2026
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Targeted radioactive therapy may help delay spread of recurrent prostate cancer
Adding the targeted radioactive drug 177Lu-PNT2002 to stereotactic body radiation therapy, or SBRT, may help keep recurrent prostate cancer under control longer than SBRT alone, according to new research led by investigators ...
Oct 13, 2026
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WHO experts recommend HPV shot for girls aged 4–8
The World Health Organization's vaccine experts recommended Tuesday that countries consider routine vaccination against HPV in girls as young as 4, provided it helps improve lagging vaccine coverage.
Oct 13, 2026
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Had genetic testing for cancer risk years ago? Newer tests may find what old ones missed
Women who had genetic testing for inherited cancer risk years ago may want to ask about testing again, experts say.
Oct 13, 2026
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Tumor suppressor gene mutations trigger immune activation in early oral cancer
Head and neck squamous cell carcinoma (HNSCC) frequently develops in the oral and upper aerodigestive regions following chronic exposure to mutagenic factors such as tobacco, alcohol and betel nut. Alterations in the tumor ...
Oct 13, 2026
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