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Oncology news
Cigarette smoke may prime lung stem cells for different types of lung cancer
Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene alterations and ultimately ...
32 minutes ago
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New imaging method links cells' spatial organization to cancer outcomes
Tumors are not made up of cancer cells alone. They also contain immune cells and other support cells that interact within a complex ecosystem known as the tumor microenvironment. A doctoral thesis by Linglong Huang at the ...
12 minutes ago
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Making pediatric cancer more 'visible' boosts immunotherapy response
High-risk neuroblastoma is one of the most aggressive forms of solid tumors affecting children, originating in the nervous system. While a newer class of targeted immunotherapy drugs has improved survival rates, according ...
1 hour ago
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One dose of protein-targeting CAR-T cells shrinks solid tumors in preclinical tests
CAR-T cell therapies have fundamentally transformed the treatment of several blood and lymph node cancers. However, their use in solid tumors such as liver, breast or lung cancer has so far been significantly more difficult. ...
4 hours ago
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Bone marrow transplant analysis reveals two distinct B-cell repertoire patterns early in recovery
A research team led by associate professors Yohei Funakoshi and Kimikazu Yakushijin and Professor Hironobu Minami of the Division of Medical Oncology/Hematology at Kobe University Hospital, together with Associate Professor ...
1 hour ago
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Scientists study breast milk as an early detection tool for breast cancer
A new study taking place in Manchester is investigating whether breast milk could help detect breast cancer earlier than a blood test or a scan. The research, led by scientists at The University of Manchester, aims to improve ...
4 hours ago
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Trial results show no survival benefit with the use of proton therapy in patients with advanced hepatocellular carcinoma
Initial results of the NRG Oncology NRG-GI003 clinical study comparing proton and photon therapy for patients with advanced hepatocellular carcinoma (HCC) indicate that proton therapy did not improve the primary objective ...
21 hours ago
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Weekly cisplatin fails to show fewer serious side effects in p16-negative head and neck cancer
Physicians typically use either a higher dose of cisplatin given every three weeks or a lower dose given weekly in combination with radiation to treat locally advanced head and neck cancer. However, before NRG-HN009, there ...
Oct 4, 2026
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Inflammation can reactivate 'sleeping' cancer cells hidden in the bone
The spread of cancer from a primary tumor to another place in the body, called metastasis, remains one of the greatest challenges in cancer treatment and is responsible for most cancer-related deaths.
Oct 2, 2026
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Same-day chemotherapy boosts cancer vaccine responses in preclinical models
Both the clinical effects and the unpleasant side effects of chemotherapies, from hair loss to mouth sores to gastrointestinal discomfort, stem from their indiscriminate destruction of cells prone to rapid proliferation. ...
Oct 2, 2026
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RNA urine test outperforms standard bladder cancer tests and could help guide treatment
A simple urine test devised by researchers at Stanford Medicine and the VA Palo Alto Health Care System can diagnose bladder cancer more accurately than current standard methods. The test also allows physicians not only to ...
Oct 2, 2026
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An epigenetic blueprint reveals how aggressive MYC amplification fuels cancer
Researchers at the Cancer Epigenetics Institute (CEI) at Fox Chase Cancer Center have discovered how to control and stop the amplification of MYC—one of the most commonly altered cancer genes linked to aggressive tumor growth ...
Oct 2, 2026
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Mass spectrometry offers faster look at the edges of brain tumors
Glioma brain tumors are diffuse, so surgeons usually cannot excise all of the cancer during surgery. Currently, surgeons remove as much of the tumor as they can and then analyze the tumor's borders after surgery.
Oct 2, 2026
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Hidden lymphatic signal amplifier could inform treatments for lymphedema and cancer metastasis
Lymphatic vessels act as the body's "drainage system," collecting excess fluid from tissues. When lymphatic drainage is impaired because lymphatic vessels are underdeveloped, damaged or dysfunctional, lymphedema can develop, ...
Oct 2, 2026
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How to manage the side effects of radiation therapy
Many of us know someone who's faced side effects of cancer treatment, like hair loss or debilitating nausea. Their experiences can make us wonder whether everyone experiences these same effects.
Oct 2, 2026
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Colorectal cancer on the rise in adolescent patients, data analysis finds
Rates of advanced-stage colorectal cancer are climbing in young patients, highlighting a need for increased vigilance, according to data presented during the American Academy of Pediatrics 2026 National Conference & Exhibition ...
Oct 2, 2026
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Discovery explains how immune cells target DNA mutations to improve antibodies
Scientists at the Montreal Clinical Research Institute (IRCM), led by Université de Montréal medical professor Javier Di Noia, have shed light on a fundamental mystery in immunology: How do immune cells manage to concentrate ...
Oct 1, 2026
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How sex chromosomes influence lifelong health beyond determining biological sex
A new review published in Science brings together growing evidence that the X and Y chromosomes do more than determine biological sex. They also shape how cells function, age and respond to disease.
Oct 1, 2026
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How loss of the critical tumor suppressor p53 enables mutant cells to expand through normal tissue
A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations. When mutations cause it to be absent or nonfunctional, its loss can allow populations of mutant cells to ...
Oct 1, 2026
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New surgical technique reconstructs the clitoris after treatment for vulvar cancer
For women who lose part of their clitoris because of vulvar cancer, a clitoral reconstruction procedure has now been developed for the first time. This comes 40 years after the first penile reconstruction surgery. Results ...
Oct 1, 2026
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PET scans reveal alpha cancer therapy isotope with new algorithm in first human test
A research team led by Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new imaging technique that could allow modern medical scanners to image targeted alpha therapy (TAT), an emerging cancer therapy ...
Oct 1, 2026
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Study finds hidden mutation rates may shape cancer risk
A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study participants had mutation ...
Oct 1, 2026
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Novel treatment combination improves progression-free survival in most common form of metastatic breast cancer
Patients with estrogen receptor-positive (ER+), HER-2-negative advanced breast cancer experienced significantly improved progression-free survival (PFS) when treated with an oral combination regimen that included giredestrant, ...
Oct 1, 2026
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Developing sustainable printing inks for functional organs
The organ transplant waiting list numbers 8,000 people each year in Germany alone, and about 10% of them never receive an organ. 3D bioprinting could help address the global shortage of donor organs by making it possible ...
Oct 1, 2026
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An omega-3 paradox: When 'healthy fats' shut down defenses against cancer
Omega fatty acids have long been recognized for their benefits: supporting cardiovascular health, reducing systemic inflammation, and promoting brain development and cognitive function. But scientists now warn of a long-unrecognized ...
