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Oncology news
DNA repair protein gene gone rogue may unlock new cancer treatments
When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells. If they stop functioning or there's not enough, cancer risk goes up. ...
16 hours ago
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Cholesterol-craving cancers need lipid enzymes to use metabolites for growth, study shows
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth ...
May 22, 2026
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Mitochondria may control immune cell activation and the effectiveness of immunotherapy
A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial checkpoint that enables dendritic cells to efficiently activate T lymphocytes against viruses and ...
May 22, 2026
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Ovarian cancer cells use stress hormone signaling to shut down immune system, research reveals
When activated in ovarian cancer cells, the receptor for the body's primary stress hormone alters the tumor environment in ways that blunt immune response, according to new research led by UT Southwestern Medical Center. ...
May 22, 2026
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Q&A: Using advanced imaging to improve brain cancer treatment
Glioblastoma is one of the most treatment-resistant brain tumors, making it especially difficult to treat. Part of that resistance stems from its unique tumor microenvironment—the complex mix of cells and biological activity ...
May 22, 2026
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New study could improve testing and treatment for rare brain, spinal cord, and eye cancers
A new study has identified hepatitis A virus cellular receptor 1 (HAVCR1) as a biomarker that could make it easier to diagnose rare but aggressive forms of brain and eye cancer earlier and with fewer invasive tests.
May 22, 2026
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Ozempic and other GLP-1 RAs could slow progression of some cancers, data suggest
Real-world data show that GLP-1 receptor agonists (GLP-1s) may reduce metastatic progression of certain obesity-related cancers, namely lung, breast, colorectal, and liver cancers. In addition, GLP-1 receptor (GLP-1R) expression ...
May 22, 2026
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New indicator for response to therapy in pediatric cancers identified
A study by researchers at the University of Birmingham has identified a new biomarker for response to a specific cancer therapy, treating children with Ewing Sarcoma and other tumor types. The study, which is a Phase I/II ...
May 22, 2026
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New AI tool may help personalize multiple myeloma treatment
An artificial intelligence-based tool may help physicians determine which newly diagnosed multiple myeloma patients are most likely to benefit from specific therapies, including immunotherapy and stem cell transplantation.
May 22, 2026
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Cancer, mood, anxiety, sleep: It's all connected, and yoga eases symptoms for survivors
University of Rochester Medicine is in the spotlight at a national meeting for a new discovery in integrative oncology: A special yoga intervention goes a step further than other therapies to improve four domains of physical ...
May 22, 2026
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Genetic clues may reveal which rare solitary fibrous tumors are more aggressive, likely to spread
Specific genetic fusion patterns in solitary fibrous tumors may help identify which patients face a higher risk of metastasis, recurrence and more aggressive disease behavior, according to new research that could improve ...
May 22, 2026
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Scientists capture 'housekeeping' immune cells attacking live melanoma
Scientists at the Garvan Institute of Medical Research have captured, for the first time, "housekeeping" immune cells actively attacking and engulfing live melanoma cells—a discovery that could change the way we approach ...
May 21, 2026
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Brain's 'tumor hotspots' uncovered in fruit fly study
New research from Peter Mac has uncovered why some parts of the brain may be more vulnerable to tumor growth than others, offering new clues into how brain cancers begin and how they could one day be stopped. Published in ...
May 21, 2026
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Decoding inflammatory bowel disease—on a chip
Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn's disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated. This is mostly due to ...
May 21, 2026
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One‑week radiotherapy course shown to be safe and effective in the long term for early‑stage breast cancer
Research led by a Keele University oncologist has found that a one-week course of post-surgery radiotherapy is just as safe and effective as the traditional three-week course for people with early-stage breast cancer. The ...
May 21, 2026
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Novel combination therapy could reduce leukemia relapse rate, extending window for bone marrow transplants
A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has developed a novel combination therapy that significantly improves treatment ...
May 21, 2026
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Data-driven biomaterials steer pancreatic cancer organoids into new cell states
Understanding and controlling how cancer cells transition between different states remains a critical challenge in tumor biology. In a recent publication in Advanced Materials, a team from the Leibniz Institute of Polymer ...
May 21, 2026
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Gut bacteria linked to immunotherapy success in melanoma patients
Researchers at The George Washington University, working with Weill Cornell Medicine, have identified specific gut bacteria linked to better responses to cancer immunotherapy in patients with advanced melanoma. The study ...
May 21, 2026
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New marker identifies patients with advanced prostate cancer more likely to benefit from combination immunotherapy
Researchers with the James P. Allison Institute at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant ...
May 21, 2026
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Targeting inflammation may help overcome drug resistance in colon cancer
Chemotherapy drugs that target a common mutation in colorectal cancer rapidly lose efficacy in patients, leading to relapse. According to a new preclinical study by Weill Cornell Medicine and MD Anderson Cancer Center investigators, ...
May 21, 2026
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Study sheds light on how early pancreas lesions become cancerous
In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying ...
May 21, 2026
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Researcher develops 'smart, tiny bubbles' to treat cancer and heart disease
A cell 500 times thinner than a human hair could heal hearts and kill cancer cells, thanks to a patent-pending technology created by a University of Central Florida researcher and now licensed to a university donor in hopes ...
May 21, 2026
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Elite immune cells lead the fight against multiple myeloma
Immunotherapy for cancer works like a guided missile, directing the body's immune cells toward tumor cells. However, not all immune cells respond to the call to attack, and this can lead to variability in treatment responses. ...
May 21, 2026
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Clinical trial tests virus-immunotherapy combination for neuroendocrine tumors
A Phase I clinical trial is testing whether a tumor-targeting virus can help immunotherapy work more effectively against aggressive neuroendocrine tumors that often resist treatment. Researchers at Sylvester Comprehensive ...
May 21, 2026
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Dermatologists and oncologists call for overhaul of widely used cancer side-effect grading system
Physicians at the Icahn School of Medicine at Mount Sinai are calling for updates to a widely used system that grades side effects from cancer treatments, warning that current criteria may misclassify the severity of skin-related ...
May 21, 2026
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