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Oncology news
Gene that drives blood cancer drug resistance uncovered with new CRISPR activation tool
Researchers have uncovered a previously unknown gene that causes resistance to a leading blood cancer drug, as well as several genes that accelerate lymphoma growth, using a powerful new CRISPR activation library.
Sep 18, 2026
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Screening method identifies leukemia drug candidates from more than 4 million compounds
A cancer cell behaves differently from a healthy cell, with unique features that enable rapid growth and bypass quality controls. Rice University's Natasha Kirienko is interested in finding these unique features and exploiting ...
Sep 18, 2026
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Restored thyroid receptor makes aggressive tumors more vulnerable to CAR-T cell therapy
Mayo Clinic researchers have identified a strategy that could help chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, overcome a major barrier to treating solid tumors: Cancer cells can change in ways that allow ...
Sep 18, 2026
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B cells may help predict risk of colitis from immunotherapy
Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown role for B cells, adaptive immune cells, in triggering and sustaining colitis as a side effect of immune checkpoint inhibitors, ...
Sep 18, 2026
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A single protein may help aggressive breast cancer spread to the brain and evade immune defenses
Researchers at Wake Forest University School of Medicine have identified a protein that may help an aggressive form of breast cancer spread to the brain and escape the body's immune defenses.
Sep 18, 2026
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Rare inherited EGFR mutation linked to dramatically increased lung cancer risk
A rare inherited mutation in the Epidermal Growth Factor Receptor (EGFR) gene is associated with a 25-fold increased risk of lung cancer, according to a study by investigators at Dana-Farber Cancer Institute and 23andMe Research ...
Sep 17, 2026
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Anti-seizure drug fights aggressive childhood brain tumors, study shows
An existing anti-seizure drug slows the growth of a devastating group of childhood cancers, new Stanford Medicine-led research has shown. The tumors, called diffuse midline gliomas, strike the brain and spinal cord. They ...
Sep 17, 2026
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Making invisible cancers visible: A new route to turn 'cold' tumors 'hot'
One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see. New research from Dana-Farber Cancer Institute scientists reveals how cancers ...
Sep 17, 2026
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Cancer biologists bring in the B-cell reinforcements for immunotherapy
Cancer is the second-leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives innovations that revolutionize cancer ...
Sep 17, 2026
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Wildfire smoke may be more harmful than other air pollution, two studies find
As climate change drives more frequent and intense wildfires, researchers at the Icahn School of Medicine at Mount Sinai have published two large-scale studies showing that wildfire smoke may pose greater health risks than ...
Sep 17, 2026
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A new AI-powered test offers more accurate prediction of breast cancer recurrence risk
A new study published in the journal npj Breast Cancer demonstrates that an artificial intelligence (AI) model offers more accurate predictions of recurrence risk in patients with early-stage breast cancer than the widely ...
Sep 17, 2026
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Blood test trends may help identify patients at increased risk of cancer
Blood test trends alongside unexplained weight loss can improve triage for cancer testing, according to a study by Brian Nicholson and colleagues from the University of Oxford, UK, published Sept. 17 in the journal PLOS Medicine.
Sep 17, 2026
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Tumor profiling reveals enzyme as a candidate target in aggressive brain cancer
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified candidate treatment targets and potential prognostic markers for high-grade glioma, an aggressive brain cancer, in children, adolescents ...
Sep 17, 2026
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Early-adult BMI may lower postmenopausal breast cancer risk through breast density
Women with a higher body mass index (BMI) in early adulthood may have a lower risk of developing breast cancer after menopause because of lasting changes in the structure of their breast tissue, according to researchers at ...
Sep 17, 2026
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Seeing metastasis before it happens: Tumor-derived extracellular vesicles for premetastatic niche imaging
Cancer is most dangerous not when it starts but when it spreads. Metastasis—the process by which cancer cells travel to and colonize distant organs—is responsible for the vast majority of cancer deaths. The problem is that ...
Annual report highlights progress in cancer research
The American Association for Cancer Research has released its annual Cancer Progress Report, highlighting recent progress in cancer research.
Sep 17, 2026
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Sexual recovery after breast cancer is often overlooked
Sexual well-being can often be overlooked during women's recovery from breast cancer, with many continuing to experience significant sexual and intimacy challenges long after treatment ends. Griffith University researchers ...
Sep 17, 2026
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Blood test shows promise for detecting pancreatic cancer at its earliest stages
Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the country, led the development of a new investigational blood test that could detect pancreatic cancer at ...
Sep 16, 2026
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Metabolite buildup reveals how aggressive brain tumors activate nearby neurons
Virtually all high-grade, aggressive gliomas in adults accumulate massive amounts of a metabolite called guanidinoacetate (GAA) that overstimulates nearby neurons and promotes tumor growth, according to new research from ...
Sep 16, 2026
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Early changes in the tumor environment may explain why immunotherapy works for some patients but not others
Two patients receive the same immunotherapy for the same cancer. In one, the tumor retreats and stays gone for years. In the other, the treatment does nothing. Oncologists still have no reliable way to tell these patients ...
Sep 16, 2026
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Machine learning system can identify cancer cells based on how they scatter light
Cytological tests are a common method of screening for cancer cells in stained cell samples. Using a microscope, pathologists examine cells collected from bodily fluids, looking for telltale signs of malignancy, like enlarged ...
Sep 16, 2026
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Fecal microbial signatures show promise for colorectal and pancreatic cancer assessment
Gastrointestinal and pancreatobiliary cancers can be difficult to detect early, creating a need for practical, noninvasive approaches for early detection and risk assessment. The gut microbiome has emerged as a potential ...
Sep 16, 2026
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Researchers find mind-body interventions ease symptoms, providing meaningful benefits after cancer treatment
The Mindfulness and Tai Chi for Cancer Health (MATCH) study looked at more than 500 cancer survivors with varying types and stages of cancer and found that patients experienced less pain, fatigue and sleep problems after ...
Sep 16, 2026
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Clinical guideline on radiation therapy for bladder cancer released
For appropriately selected patients with muscle-invasive bladder cancer, preserving the bladder can be a curative treatment option rather than removing it, according to a new clinical guideline from the American Society for ...
Sep 16, 2026
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Minibeam radiotherapy studied in patients with difficult-to-treat cancers
Mayo Clinic researchers report encouraging results using a new radiation technique called minibeam radiotherapy to treat patients with treatment-resistant cancers in or near the skin. The technique delivers very high doses ...
Sep 16, 2026
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