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Oncology news
Statins emerge as potential cancer immunotherapy boosters
Cancer immunotherapy has transformed modern oncology by harnessing the body's own immune system to combat malignant disease. Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have produced durable responses in ...
58 minutes ago
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Research improves risk assessment for hereditary breast cancer
Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer. By identifying which mutations affect the function of PALB2, doctors can now assess much more ...
47 minutes ago
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Treatment possible after positive liquid biopsy in primary central nervous lymphoma patients
A group led by the Department of Neurosurgery at the Brain Research Institute, Niigata University, has successfully diagnosed 10 primary central nervous system lymphoma (PCNSL) patients who had difficult-to-access lesions ...
45 minutes ago
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New nanotherapy eases bone metastasis pain by disrupting tumor-nerve crosstalk
A new nano-sized drug carrier that finds bone tumors and releases treatment exactly where it's needed is here to improve the precision and comfort of cancer therapy. Designed by a team of researchers from China, this smart ...
Fecal transplant can improve response to immunotherapy in advanced kidney cancer
An Italian study published in Nature Medicine provides compelling evidence that fecal microbiota transplantation (FMT) can enhance the effectiveness of immunotherapy in patients with advanced metastatic renal cell carcinoma ...
10 hours ago
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New 'lab-on-a-disc' device paves the way for more automated liquid biopsies
Extracellular vesicles (EVs) are tiny particles shed by cells that carry important molecular "clues" about the cell's identity and condition. EVs in blood vary widely and are mixed with many other particles, making them difficult ...
10 hours ago
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Investigational blood biomarker panel may improve detection of pancreatic cancer
A four-biomarker blood panel of aminopeptidase N (ANPEP), polymeric immunoglobulin receptor (PIGR), CA19-9, and thrombospondin-2 (THBS2) enhanced the detection of pancreatic ductal adenocarcinoma (PDAC) compared to measuring ...
9 hours ago
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Subcutaneous delivery of hyaluronidase may boost effectiveness of cancer immunotherapy
Monash University researchers, alongside key partner Halozyme Therapeutics, report findings in support of shifting the way anti-cancer immunotherapy is administered from intravenous administration to subcutaneous administration ...
9 hours ago
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Massachusetts closest to eliminating cervical cancer, Southeastern states lag, new study finds
Eliminating cervical cancer is possible. The goal is years away and varies widely by state, according to a new paper by researchers at MUSC Hollings Cancer Center, said lead author Trisha Amboree, Ph.D., published in JNCI ...
10 hours ago
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Clinical practice guidelines on diagnosis of light chain amyloidosis published
The American Society of Hematology (ASH) released guidelines on the diagnosis of light chain (AL) amyloidosis, a rare and life-threatening disease of the bone marrow. The guidelines, published in the journal Blood Advances, ...
5 hours ago
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Novel laser therapy device generates promising results in prostate cancer clinical trial
Because treatment of the whole prostate can lead to long-term side effects in patients with prostate cancer, interest in minimally invasive, focal treatment options has been growing for certain patients. A clinical trial ...
12 hours ago
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Computational method clarifies gene–drug links for precision cancer treatment
A paper published in Biology Methods and Protocols, indicates that a new computational method may help researchers identify effective precision treatments for cancer more quickly and efficiently. The paper is titled "SOLVE: ...
15 hours ago
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Antibody-producing immune cells can help shape cancer immunotherapy
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.
19 hours ago
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Lab-grown organoids reveal how glioblastoma outsmarts treatment
UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer ...
20 hours ago
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3D chip platform enables animal-free testing in cancer research
Cancer research laboratory tests can now be done using micro-physiological systems mimicking human physiology, allowing greater predictive accuracy for human patient responses, thanks to an international scientific team led ...
22 hours ago
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When patients report symptoms, clinicians can judge cancer treatment side effects more consistently
A large multinational clinical trial has found that giving health care providers access to European Organization for Research and Treatment of Cancer (EORTC) patient-reported outcome (PRO) data significantly improves the ...
23 hours ago
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Deciphering chaos: New 'fuzzy' AI predicts battle between immune system and cancer
Understanding how a tumor evolves against the attack of the immune system is one of the greatest challenges in modern medicine. Current mathematical models are usually deterministic; that is, they assume fixed values that ...
Jan 27, 2026
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New therapeutic target for breast cancer involves double-stranded RNA-binding proteins
A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle Cottrell, an assistant professor of biochemistry, spotlights double-stranded ribonucleic acid (dsRNA)-binding ...
Jan 27, 2026
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A shared process underlies oral cancer pain and opioid tolerance
Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and makes opioids less effective. The findings point to a shared mechanism underlying both oral cancer pain ...
Jan 27, 2026
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Researchers advance understanding of female sexual anatomy to improve pelvic cancer radiotherapy
Researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with other leading institutions across the country, have published an innovative study that provides radiation oncologists with practical guidance ...
Jan 27, 2026
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Deep-learning algorithms enhance mutation detection in cancer and RNA sequencing
Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic mutation detection in cancer ...
Jan 26, 2026
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As taurine fuels leukemia, it may also impact bone health
In a basic science study last year, researchers discovered that taurine, available in energy drinks and as a supplement, feeds the growth of leukemia stem cells. A new study recently published by the same Wilmot Cancer Institute ...
Jan 26, 2026
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Cancer's secret safety net: A hidden mechanism lets dangerous mutations thrive
Researchers in Class of 1942 Professor of Chemistry Matthew D. Shoulders' lab have uncovered a sinister hidden mechanism that can allow cancer cells to survive (and, in some cases, thrive) even when hit with powerful drugs. ...
Jan 26, 2026
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Li-Fraumeni syndrome: How the immune system may shape inherited cancer risk
Li-Fraumeni syndrome is a rare hereditary disease that significantly increases the risk of developing cancer. Almost all affected individuals receive a cancer diagnosis at least once in their lifetime. A new study suggests ...
Jan 26, 2026
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Higher lifetime alcohol consumption linked to colorectal cancer risk
Studies have demonstrated a link between alcohol consumption and an elevated risk of colorectal cancer. New research now reveals that higher lifetime alcohol consumption is also associated with a higher risk, especially for ...
Jan 26, 2026
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