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Oncology news
Scientists now know why ovarian cancer spreads so rapidly in the abdomen
Ovarian cancer kills more women than any other gynecological cancer. Most patients receive their diagnosis only after the disease spreads throughout the abdomen. Until now, scientists have never fully understood why this ...
4 hours ago
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Experimental bioadhesive patch sticks to wet brain tissue and wipes out most glioblastoma cells
Glioblastoma is the most prevalent and aggressive brain tumor. It proliferates very rapidly, is highly invasive, and there is currently no treatment capable of halting its progression or curing it, which means life expectancy ...
4 hours ago
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ABCA1 protein releases molecular brakes on solid tumor immunotherapy, study finds
In recent years, cancer researchers have made major breakthroughs by using the body's immune system to fight cancer. One of the most promising approaches, known as immune checkpoint blockade, works by releasing molecular ...
4 hours ago
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Americans prefer to screen for cervical cancer in-clinic vs. at home, finds study
American women now have the option of screening for cervical cancer at home, using newly approved self-collection tools. While experts hope this will increase uptake in the under-screened population, a first-of-its kind study ...
3 hours ago
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'Sticky coat' boosts triple negative breast cancer's ability to metastasize
Researchers at Baylor College of Medicine have uncovered a strategy that triple negative breast cancer (TNBC) cells use to boost their ability to metastasize, or spread to other organs. Metastasis is the leading cause of ...
6 hours ago
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Can chemo-resistant cancer cells be resensitized?
Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged cancer cells into a state ...
3 hours ago
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Dual-action molecule design concentrates cancer treatment in tumor cells to allow higher doses
Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more effectively. The new approach could be a way to deliver treatment directly to tumors at higher doses, while ...
4 hours ago
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CRISPR approach turns oncogene amplification into a weakness in multiple solid tumors
The onset and aggressiveness of cancer are related to the abnormal behavior of certain genes, known as oncogenes. The best-known of these alterations is mutation, but it is not the only one. Sometimes, within a cell, a very ...
4 hours ago
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Understanding how cancer cells use water pressure to move through the body
Cancer is one of the leading causes of death worldwide, marked by the uncontrolled growth of abnormal cells. What makes it more dangerous is the ability of cancer cells to move quickly through the body, allowing them to invade ...
4 hours ago
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RNA therapeutics shrink metastasized lung tumors in mouse study
A new study in mice hints at the potential to use tiny particles made with RNA molecules to deliver chemotherapy drugs and other therapies directly to tumors, killing cancer cells without generating an immune response or ...
8 hours ago
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Why some breast cancers evade treatment: Protein secreted by T cells may explain resistant tumors
Up to 20% of hormone receptor-positive breast cancers don't respond to antiestrogen therapies. A study led by researchers at UT Southwestern, published in the Journal of Clinical Investigation, suggests that a protein secreted ...
9 hours ago
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Immune 'hijacking' by tumors can predict cancer evolution
Predicting tumor progression is one of the major challenges in oncology. Scientists at the University of Geneva (UNIGE) and the Ludwig Institute for Cancer Research have discovered that neutrophils, a type of immune cell, ...
Feb 5, 2026
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Trojan horse delivery system uses gold nanoparticles to drive mRNA into tumors
University of Oklahoma researchers have created a new drug delivery system that helps cancer cells take in much more of a treatment, improving its ability to kill tumors. The findings are published in Science Advances.
Feb 5, 2026
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AI tool predicts brain age, cancer survival and other disease signals from unlabeled brain MRIs
Mass General Brigham investigators have developed a robust new artificial intelligence (AI) foundation model that is capable of analyzing brain MRI datasets to perform numerous medical tasks, including identifying brain age, ...
Feb 5, 2026
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Pandemic disruptions to health care worsened cancer survival, study suggests
During the early years of the COVID-19 pandemic, experts worried that disruptions to cancer diagnosis and treatment would cost lives. A new study suggests they were right.
Feb 5, 2026
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Five mutational 'fingerprints' could help predict how visible tumors are to the immune system
Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's not simply the number of tumor mutations that matters for immunotherapy, but the kind of mutation ...
Feb 5, 2026
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Approved arrhythmia drug may slow MYC-driven lymphoma by blocking USP11 interactions
A team of researchers at VCU Massey Comprehensive Cancer Center discovered an innovative way to use a drug already approved for treating irregular heartbeat to selectively target specific functions of enzymes in lymphoma, ...
Feb 5, 2026
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FDA approves quadruplet regimen for adults with newly diagnosed multiple myeloma
The U.S. Food and Drug Administration has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj) in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for the treatment of adult patients with newly ...
Feb 5, 2026
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A genetic blueprint for avoiding killer T cell exhaustion
A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune ...
Feb 4, 2026
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High consumption of ultraprocessed foods may be linked to cancer survivors' risk of death
Ultraprocessed foods can be considered unhealthy because they are often low in essential nutrients such as vitamins, minerals, and fiber, and the industrial processing methods used to produce them introduce additives, artificial ...
Feb 4, 2026
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An off-the-shelf immunotherapy for targeting solid tumors: Ready-to-use CAR-NKT cells show promise
A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to treat multiple solid tumors. The study focused on engineered invariant natural killer T cells, or ...
Feb 4, 2026
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Small molecule blocks key glioblastoma driver, raising hopes for new treatment
UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for the deadliest brain cancer. ...
Feb 4, 2026
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A double-edged sword: Chronic cellular stress promotes liver cancer—but also makes tumors vulnerable to immunotherapy
A key molecular mechanism drives the growth of liver cell cancer while simultaneously suppressing the body's immune response to the tumor. This has been published in the journal Nature by a team led by researchers from the ...
Feb 4, 2026
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Testing menstrual blood for HPV could be 'robust alternative' to cervical screening
Testing menstrual blood for human papillomavirus (HPV) could be a "robust alternative or replacement" for current cervical cancer screening by a clinician, finds a study from China published by The BMJ. The researchers say ...
Feb 4, 2026
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Agent Orange exposure identified as a risk factor for rare skin cancer
A study of U.S. veterans led by investigators at Mass General Brigham has identified a possible link between exposure to the Agent Orange herbicide and a rare melanoma subtype less likely to be related to sun exposure. The ...
Feb 4, 2026
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