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Oncology news
Tomosynthesis detects breast cancer more frequently during screening
With around 75,000 new cases per year, breast cancer is by far the most common cancer among women in Germany. Using digital breast tomosynthesis in the breast cancer screening program could prevent around a quarter of invasive ...
2 hours ago
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Exploring the potential of immunotherapy in early-stage triple-negative breast cancer
Triple-negative breast cancers, which are more frequently diagnosed in younger women, are a subtype of breast tumor characterized by the absence of hormone receptors and HER2 overexpression. As a result, they do not respond ...
1 hour ago
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AI-based computer model offers new weapon against hard-to-treat cancers
In a new paper published in Cell Reports Medicine, the UCL team outlines how they, in collaboration with a University of Cambridge team, developed a new type of treatment-predicting computer program that uses an individual's ...
12 hours ago
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Next-generation drug reduces endometrial cancer progression and death in trial
A new drug is effective at decreasing the recurrence of, and death from, endometrial cancer, an international study shows. The drug, called sacituzumab tirumotecan (sac-TMT), attaches to a protein on the surface of tumor ...
13 hours ago
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Implantable device uses ultrasound to improve drug delivery to the brain
Patients with glioblastoma, an aggressive type of brain tumor, usually undergo surgery to remove the tumor. However, it's difficult for surgeons to remove all of the cancer cells, and the tumor often recurs.
13 hours ago
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New targeted therapy improved survival for patients with KRAS-mutated lung cancer
Patients with previously treated advanced KRAS G12C-mutant non-small cell lung cancer (NSCLC) lived significantly longer and saw improved disease control when treated with the next-generation KRAS-targeted therapy divarasib, ...
8 hours ago
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Immunotherapy combo extends survival for patients with aggressive small cell lung cancer, based on trial results
In patients with extensive-stage small cell lung cancer (ES-SCLC), tarlatamab, a bispecific T-cell engager, plus durvalumab as first-line maintenance therapy extended median overall survival by more than eight months, more ...
10 hours ago
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Metabolic vulnerability identified in small cell lung cancer
Researchers at the University of Cologne have demonstrated that, while various cellular states of small cell lung cancer are equally dependent on the amino acid cysteine, they react differently when deprived of it. While ...
12 hours ago
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Immunotherapy combination extends survival in advanced endometrial cancer
An immunotherapy-based regimen combining durvalumab and the PARP inhibitor olaparib demonstrated encouraging long-term survival outcomes for patients with advanced or recurrent endometrial cancer, according to new trial results ...
13 hours ago
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Patients given apalutamide and hormone therapy around surgery may cut their risk of metastasis or death
An international phase 3 clinical trial that treated patients with high-risk localized and locally advanced prostate cancer with apalutamide—a next-generation neoadjuvant androgen-receptor pathway inhibitor (ARPI)—plus hormone ...
7 hours ago
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New treatment approach shows promise in reducing prostate cancer spread
Adding darolutamide to standard treatment for aggressive prostate cancer reduced the risk of the disease spreading in an international phase 3 trial.
9 hours ago
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Location of rare cancer impacts survival, study suggests
A rare, aggressive cancer, commonly found in the uterus, limbs and abdomen, behaves differently depending on where it is found in the body, according to new research.
8 hours ago
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Fructose slows liver tumors in mice when key sugar-processing gene is missing, may lead to new treatments
Fructose is an important nutrient that, despite having a chemical structure very similar to that of glucose, is metabolized very differently in the body. Research into fructose metabolism and its regulation of metabolism ...
10 hours ago
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Black patients can face longer breast cancer care delays, study finds
Black patients and people with a learning disability face longer waiting times at key stages of breast cancer care, according to a nationwide study led by the University of Surrey.
12 hours ago
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AI could help identify people at higher risk of common cancers using routine health data
Machine learning models using routinely collected health information, such as blood tests, medical history and lifestyle factors, could help identify people at higher risk of several common cancers, according to an international ...
13 hours ago
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Biomarkers identified for cytokine release syndrome risk after CAR T-cell therapy
For patients with autoimmune disease, higher baseline B-cell counts and systemic inflammation are associated with development of cytokine release syndrome (CRS) after chimeric antigen receptor (CAR) T-cell therapy, according ...
10 hours ago
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Personalized cancer vaccine plus immunotherapy reduces melanoma recurrence after surgery
Adding a personalized mRNA-based cancer vaccine to immunotherapy after surgery for high-risk melanoma reduced the risk of recurrence or death by 42%, according to results from the phase 3 INTerpath-001 trial presented at ...
7 hours ago
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Adding abiraterone to ADT and docetaxel improves survival in metastatic prostate cancer
Adding abiraterone to standard treatment provides a lasting survival benefit for men whose prostate cancer has already spread at diagnosis, reinforcing the value of early treatment intensification. The findings come from ...
15 hours ago
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Omega-3 EPA linked to longer survival after surgery for colorectal cancer liver metastases
Patients assigned to receive high-dose eicosapentaenoic acid (EPA), an omega-3 fatty acid, before and after surgery for colorectal cancer liver metastases had longer overall survival than those assigned to receive placebo, ...
15 hours ago
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Fewer US men are diagnosed with low-risk prostate cancer, and more of them now choose surveillance over treatment
An analysis of United States data reveals a broad shift away from overtreatment of low-risk prostate cancer. The analysis published in CANCER indicates a shift toward surveillance in response to concerns of overdiagnosis ...
21 hours ago
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Young adults with cancer report putting off appointments, getting dismissed by doctors
When Natasha Allard's close friend Dave was diagnosed with stage 4 testicular cancer at age 26, the University at Buffalo postdoctoral associate started paying more attention to how cancer was upending the lives of young ...
Oct 25, 2026
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Investigational vaccine generates immune response to KRAS mutations in pancreatic cancer study
An investigational vaccine helped the immune system recognize and respond to mutations that drive most pancreatic cancers, according to results from a randomized phase 2 clinical trial led by Mayo Clinic researchers. The ...
Oct 24, 2026
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How cancers evade chemotherapy by entering a 'zombie-like state'
Scientists at Trinity College Dublin have made a breakthrough in understanding how cancer cells can evade the cell-killing effects of chemotherapy and enter a "zombie-like state," called premature senescence, that can attract ...
Oct 23, 2026
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A precision T-cell therapy stalls treatment-resistant cancers in clinical trial
Early results of the first clinical trial to evaluate the drug invikafusp alfa (invika) in humans indicate that the treatment may be capable of managing cancers that have rebuffed most other interventions, including standard ...
Oct 23, 2026
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Cancer cells' own carbon monoxide fuels anticancer drug production in lab tests
What if we could use a cancer's own byproduct to make drugs that destroy tumor cells from the inside? That is what Katsunori Tanaka and his team have done at the RIKEN Pioneering Research Institute (PRI) in Japan.
Oct 23, 2026
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