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Oncology news
A 'molecular switch' that heals the gut—and that colorectal cancer hijacks to spread
Digestion is hard on the cells that line the human gut, and they are constantly being shed and replaced. This renewal is driven by a population of tireless stem cells. These stem cells can both replace the various types of ...
9 hours ago
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Tumor-secreted protein makes lung vessels leakier, promoting metastasis
A protein secreted by common cancer types makes blood vessels leakier to allow metastatic tumors to form in the lungs, according to a study led by investigators at Weill Cornell Medicine and Memorial Sloan Kettering Cancer ...
10 hours ago
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A new drug that can potentially overcome cancer therapy resistance
Researchers at Baylor College of Medicine have developed a drug called CS18 that disrupts cancer cells' ability to survive therapy. The findings, published in Science Advances, support exploring the possibility of using CS18 ...
14 hours ago
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Cancer Dependency Map now includes next-generation 3D cancer models
For nearly a decade, the Cancer Dependency Map, or DepMap, at the Broad Institute has helped scientists uncover new cancer dependencies—the genetic changes some cancers need to thrive that can potentially be targeted by new ...
14 hours ago
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International project delivers hundreds of next-generation models for cancer research
Ten years and thousands of patient samples later, the National Cancer Institute (NCI) has published its results from the Human Cancer Model Initiative (HCMI) on the development of 665 organoid models of 25 types of cancer ...
17 hours ago
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Immune cell dysfunction, not absence, defines skin cancer in immunosuppressed patients
Researchers at The University of Texas MD Anderson Cancer Center have discovered that immunosuppressed patients with non-melanoma skin cancer are not missing the key cancer-fighting immune cells found in immunocompetent patients, ...
10 hours ago
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Cancer cells hijack a fatty acid to escape immune attack in liver metastases
Liver metastases are among the most common and deadly forms of cancer spread. Now, researchers at VIB and KU Leuven, with international collaborators, have discovered how cancer cells exploit a fatty acid abundant in the ...
13 hours ago
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First-in-class small molecule inhibitor shows promise against pancreatic cancer in preclinical studies
Mayo Clinic researchers have developed an experimental drug with the help of artificial intelligence (AI) to target the "undruggable" PDZ domain of the GIPC1 protein, which helps different types of cancer, including pancreatic ...
14 hours ago
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New biobank of tumor models reveals cancers' weak spots
A new open resource of cancer models has enabled researchers to create the first large-scale map of the genes that cancers rely on to survive, offering new avenues for research into better and less toxic treatments for patients.
17 hours ago
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Regular checks sustain high participation for children with inherited cancer risk
Children born with a pathogenic variant in the TP53 gene, known as Li-Fraumeni syndrome, have a markedly increased risk of developing various types of cancer, often at a young age. Therefore, they undergo regular surveillance ...
17 hours ago
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Tumor-like tissue environments could hold clues to curing HIV
The tissue microenvironments surrounding HIV-infected immune cells look a lot like those surrounding cancerous tumors, reports a new Northwestern University study.
20 hours ago
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Researchers discover immune 'off switch' used by cancer cells
Mayo Clinic researchers have identified a protein that cancer cells use to shut down the body's immune response, a discovery that could help scientists develop new treatments that make cancer immunotherapies more effective.
Aug 4, 2026
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Implant design helps fight ovarian cancer from the inside
Researchers have developed an implant that could deliver next-generation therapies for ovarian cancer precisely where they are needed while simultaneously monitoring how the disease responds.
Aug 4, 2026
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Turning a common oncogene's metabolic grip on cancer cells into a fatal weakness
For all its persistence as an adversary, aggressive breast cancer carries a weakness of its own making. A University of Helsinki research group has been investigating where this weakness comes from and how it can be exploited. ...
Aug 4, 2026
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AI tool for computing radiation dose helps personalize prostate cancer treatment
Radiopharmaceutical therapy (RPT) has made significant strides over the past 50 years, although it only recently received FDA approval to treat prostate cancer. But despite the progress—and billions of dollars in industry ...
Aug 4, 2026
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Researchers discover how tumors enlist nerves to keep growing
New research from the University of Oklahoma demonstrates how an aggressive form of breast cancer co-opts the body's own immune system to attract nerves that fuel tumor growth.
Aug 4, 2026
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Combination of targeted therapies could help overcome treatment resistance in advanced prostate cancer
UCLA researchers have identified a promising strategy to make a new class of targeted cancer therapies more effective against one of the deadliest forms of prostate cancer, potentially overcoming treatment resistance that ...
Aug 4, 2026
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Triple drug combination shows promise against fatal blood cancer
Acute myeloid leukemia (AML) is an aggressive blood cancer that remains difficult to treat. While targeted therapies have improved outcomes for some patients, many relapse when a small population of cancer stem cells survives ...
Aug 4, 2026
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Aberrant protein activity rewires lymphoma cells to survive BTK inhibitors, offering target for treatment resistance
A protein that can dial down oxidative stress in cells helps some cancers resist treatment with a widely used class of drugs called BTK inhibitors, according to a study led by investigators at Weill Cornell Medicine. The ...
Aug 4, 2026
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Cost and access: The barriers stopping Aboriginal men getting prostate cancer surgery
Aboriginal and Torres Strait Islander men diagnosed with prostate cancer are less likely to receive surgery than other Australian men and more likely to face financial barriers to treatment, according to the largest Australian ...
Aug 4, 2026
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New therapy shrinks tumors to treat lung cancer
The need for more effective lung cancer treatments is paramount, as the disease remains a leading cause of cancer deaths in the United States. New findings by a research team from the Stony Brook Cancer Center highlight a ...
Aug 4, 2026
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Confronting global gaps in integrative cancer care knowledge
More than 8 in 10 cancer care providers worldwide say they don't know enough about integrative oncology to confidently recommend it to patients. That finding, from a global survey led by researchers at the University of California, ...
Aug 4, 2026
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Scientists unmask immune cells that supercharge the fight against cancer
A little-known group of hard-to-find immune cells could help transform cancer treatment, scientists at the University of Manchester's Cancer Research UK Manchester Institute have found. Their discovery, accepted for publication ...
Aug 4, 2026
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Intratumoral Fusobacterium as a prognostic and predictive biomarker in resectable colorectal cancer
The first results from the multicenter FUSOMAP project, published in ESMO Open and led by VHIO's Molecular Oncology Group, show that the presence of intratumoral Fusobacterium in surgical tumor samples identifies a clinically ...
Aug 4, 2026
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Biochemists discover new strategy to combat pediatric bone cancer
Researchers at the UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center are zeroing in on less toxic and more targeted strategies to combat Ewing sarcoma, an aggressive and rare pediatric cancer that develops ...
Aug 4, 2026
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