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Oncology news

More sensitive HIT cell therapy shows promise against solid cancers

CAR T cell therapy has revolutionized the treatment of many blood cancers, but has shown little success against solid tumors, which account for over 85% of all cancers. Columbia researchers have now found that a new type ...

A potential immunotherapy strategy for early-stage prostate cancer

Immunotherapy has been generally ineffective for prostate cancer because the tumors are considered immunologically "cold," meaning they do not attract enough immune cells to mount a strong attack. Hormone therapy commonly ...

A promising new drug for an invasive type of breast cancer

EPFL researchers have developed preclinical models for invasive lobular carcinoma and trialed a new drug. It slows tumor growth effectively by targeting specific features of the disease and opening the door to future clinical ...

Paradigm shift in immune checkpoint biology

A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, providing new mechanistic ...

Vitamin B7 reveals a new metabolic weak spot in some cancers

A research group at the University of Lausanne (Unil) has identified a new mechanism that exposes the vulnerability of tumor cells when they are deprived of vitamin B7. The ability of cells to adapt to fluctuations in nutrient ...

Gallbladder cancer could soon be detected in blood

Researchers at Tezpur University in Assam, India, working with scientists at the University of Illinois Urbana-Champaign, have identified distinct chemical signatures in blood that could help detect gallbladder cancer earlier. ...