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Oncology news
This hand-held cancer probe feels what surgeons may miss and changes how tumors are found in real time
Breast cancer impacts over two million women around the world each year. Following radiotherapy or chemotherapy, breast-conserving surgery is the first line of intervention for early-stage breast cancer. This surgery aims ...
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Study surveys dysfunctional gene splicing in metastatic kidney disease
Researchers at City of Hope and TGen (part of City of Hope) have identified a significant correlation between a tumor's "splicing burden" and its clinical response to treatment for metastatic renal cell carcinoma (mRCC). ...
1 hour ago
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Complete remission of aggressive pituitary tumor achieved through immunotherapy
Researchers at the University of Cincinnati Gardner Neuroscience Institute's Brain Tumor Center have been confirmed as the first in the world to achieve complete remission of a rare pituitary cancer using a novel immunotherapy ...
21 hours ago
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Enzyme shields triple-negative breast cancer cells from replication stress
Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme—RNase H2—that helps triple-negative breast cancer (TNBC) cells survive high levels of DNA replication stress. Because many breast ...
19 hours ago
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FDA grants expanded access to the pancreatic cancer drug daraxonrasib
The U.S. Food and Drug Administration (FDA) has granted expanded access for the use of an experimental pancreatic cancer drug, daraxonrasib. This means the drug will be available for early access to those who previously received ...
15 hours ago
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ASBrS: Robotic nipple-sparing mastectomy safe, effective in early breast cancer
For patients with early-stage breast cancer, robotic nipple-sparing mastectomy (rNSM) is as safe and effective as open NSM, according to a study presented at the annual meeting of the American Society of Breast Surgeons, ...
17 hours ago
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One missing metabolic step can turn cancer's DNA-copying machinery into a lethal weakness
Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern ...
May 4, 2026
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Mistletoe extract shows no effect in patients with advanced pancreatic cancer
New research shows that palliative patients with pancreatic cancer neither live longer nor experience improved quality of life when taking mistletoe extract in addition to standard cancer treatment, compared to placebo. The ...
May 4, 2026
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Some breast cancer survivors need closer heart disease monitoring
The racial makeup and socioeconomic status of early-stage breast cancer patients could offer clues about their risk for heart disease, the leading cause of death among breast cancer survivors. Results of a study led by a ...
May 4, 2026
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Proteins found in cancer extracellular vesicles could guide drug development
Cancer cells release tiny biological packages called extracellular vesicles (EVs) that help tumors grow and spread. A team led by Cedars-Sinai Health Sciences University investigators has now connected certain proteins carried ...
May 4, 2026
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Blocking a cellular inflammation process could result in effective therapy for pancreatic cancer
Scientists at The Wistar Institute and clinical researchers from ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a vulnerability in pancreatic cancer that could be targeted as a potential ...
May 3, 2026
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Low-dose drug cuts breast density up to 26% with fewer side effects
Low doses of the investigational medicinal product endoxifen reduce breast density to the same extent as the standard treatment tamoxifen, but without causing such troublesome side effects. This is shown by a new study from ...
May 3, 2026
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Liquid biopsy predicts response to breast cancer immunotherapy
Immunotherapy has become a standard of care in treating high-risk, early-stage breast cancers, yet it has had limited success in shrinking tumors. New biomarkers that can improve outcomes for patients are urgently needed. ...
May 3, 2026
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Blood test shows promise for detecting testicular cancer when standard markers miss
Mayo Clinic researchers have developed a blood-based method that may help detect germ cell tumors, the most common type of testicular cancer, including cases that do not show up on standard blood tests, according to a study ...
May 3, 2026
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Experimental KRAS G12D drug slows cancer growth, shrinks tumors in early test
A first-in-human clinical trial led by an international team of researchers and published in the New England Journal of Medicine found that setidegrasib, an investigational targeted therapy drug designed to eliminate a key ...
May 2, 2026
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Microchip nanoparticle test spots pancreatic cancer in blood, outperforming biopsy in early trial
Scientists at Oregon Health & Science University have developed a new technique using an electronic jolt and nanoparticles to reveal the telltale signal of an insidious form of cancer.
May 2, 2026
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New test promises to detect cancer earlier, from tiny particles in bodily fluids
Cancer claims more than 10 million lives every year globally. Research shows that detecting cancer early can greatly improve a patient's chance of survival. And yet we lack reliable, affordable tools for early detection.
May 2, 2026
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Medicaid restrictions could lead to over 1 million missed cancer screenings
A research letter from experts at the University of Chicago Medicine, published in JAMA Oncology, warns that upcoming funding cuts and changes to federal Medicaid eligibility rules could lead to dramatic reductions in cancer ...
May 2, 2026
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Why some aplastic anemia patients recover: Protective blood stem cell clones may restore marrow
Aplastic anemia is a rare, life-threatening blood disorder where patients are unable to make enough blood cells due to the immune system's attack on blood stem cells. The condition can progress to myelodysplastic syndrome ...
May 1, 2026
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Pancreatic cancer 'playbook' reveals why survival remains just 13% after 5 years
Researchers at Trinity College Dublin have published a major new review that brings fresh clarity to one of the deadliest forms of cancer—pancreatic cancer—by mapping how the disease operates at every level. The review is ...
May 1, 2026
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CDK inhibitors show wider cancer potential as combinations and biomarkers advance
Worldwide, more than a million breast cancer patients have been treated with cyclin-dependent kinase 4/6 (CDK4/6) inhibitors, which slow or stop the uncontrolled multiplication of cancer cells. Researchers see untapped potential ...
May 1, 2026
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Dietary fats shape pancreatic cancer risk via ferroptosis
For decades, the relationship between fat and cancer has been treated as a question of quantity: Eat less fat, reduce your risk of developing cancer. But new research published April 29 in Cancer Discovery shows that for ...
May 1, 2026
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High-intensity exercise after breast cancer surgery may help speed recovery
After breast cancer surgery, many women are told to limit how much—and how soon—they exercise.
May 1, 2026
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Experts offer perspective on link between pesticide exposure and early-onset colorectal cancer
Advanced technologies are helping researchers identify environmental contaminants that could potentially be contributing to the rising incidence of early-onset colorectal cancer. However, epigenetic studies on such associations ...
May 1, 2026
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Why this CAR T advance matters: Complete remissions without chemotherapy at doses as low as 250,000 cells/kg
Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and mount potent anti-tumor responses. These properties make them an attractive candidate for next-generation ...
Apr 30, 2026
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