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Oncology news
Scientists decipher how T cells sense enemies—such as cancer—at point of contact
Every encounter between a T cell and a potential target—especially when that target is a developing tumor—begins with a rapid series of molecular decisions. Within seconds, the immune cell must determine whether to launch ...
16 hours ago
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Engineered gut bacteria show promise against pancreatic cancer
Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a "cold" tumor microenvironment, where ...
9 hours ago
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Brain metabolism predicts survival in advanced non–small cell lung cancer patients
Low brain metabolism as measured by ¹⁸F-FDG PET/CT is associated with higher mortality in patients with advanced non-small cell lung cancer (NSCLC), according to new research published in The Journal of Nuclear Medicine. ...
2 hours ago
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AI analysis could help tailor intensified treatment for locally advanced rectal cancer
Artificial intelligence developed by researchers at UCL has revealed a promising combination of cancer treatments that could help patients with locally advanced rectal cancer live longer.
5 hours ago
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Study finds new weak spot linked to DNA repair in aggressive, drug-resistant cancers
A new way for hard-to-treat cancer cells to protect themselves from being killed by anticancer drugs has been found. The novel method involves tumors hijacking specific defenses for repairing damaged DNA, which are easier ...
6 hours ago
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Synthetic tumor data helps AI improve long-read cancer mutation detection
A research team at The University of Hong Kong (HKU), has developed ClairS—a deep-learning algorithm that significantly improves the detection of cancer mutations using long-read sequencing. Tested on breast cancer, lung ...
12 hours ago
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Turning COVID-19 immune memory into a powerful new ally against cancer
In a discovery that could redefine the future of cancer immunotherapy, scientists from Celloram Inc., University Hospitals and Case Western Reserve University have developed a novel cancer vaccine platform that transforms ...
7 hours ago
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Some animals catch cancer from others in their species. Here's why humans aren't one of them
Scientists in Vermont have just discovered something that shouldn't really be possible: a skin cancer that's spreading from catfish to catfish. It's only the fourth transmissible cancer ever found in nature.
6 hours ago
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Study finds shift away from cigarettes could reshape future cancer burden
As cigarette smoking reaches historic lows in the U.S., new research from MUSC Hollings Cancer Center suggests a fundamental shift in tobacco use is driving that trend. Younger adults are increasingly switching to noncombustible ...
12 hours ago
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Understanding financial conflicts of interest in cancer care and research
Cary Gross, MD, professor of medicine (general internal medicine) at Yale School of Medicine, has studied financial conflicts of interest in American medicine for more than 20 years. In a recent systematic review published ...
14 hours ago
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'Pro version' of cisplatin keeps its cancer-killing power while reducing side effects
Cisplatin is one of the most successful cancer medicines ever developed. Doctors use it to treat many cancers, including lung, ovarian, breast, testicular and head and neck cancers. However, cisplatin has a serious problem. ...
Autoantibodies could shape cancer risk, growth and response to immunotherapy
Scientists have long sought to understand why some people with no known risk factors develop cancer while others with significant risk never do. The answer may lie in immune proteins known as autoantibodies (auto-Abs), suggests ...
Jul 25, 2026
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New mechanoresistant cancer cells show how they survive high stress environments
When a cancer cell leaves the original tumor to spread to a new, faraway location, it first has to survive what most cells cannot: periodic high-force moments in the vessels and heart of up to 5,000 dynes per centimeter squared ...
Jul 24, 2026
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Giving antibodies 'eyes' may help target hidden KRAS mutations in cancer cells
Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have remained a "blind spot" for treatment because antibodies cannot reach them. KAIST researchers have now ...
Jul 24, 2026
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Redesigned lung cancer drug matches tumor control with fewer off-target interactions
Researchers at Moffitt Cancer Center have developed a new chemical approach that could help make targeted cancer medicines safer and more precise. The discovery gives scientists a new way to design drugs that bind more selectively ...
Jul 24, 2026
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Tiny BAP1 mutations can disrupt internal signals that suppress tumor growth
Scientists at the Institute of Biochemical Sciences at National Taiwan University have uncovered how tiny genetic changes can disable one of the body's most important tumor-suppressing proteins. Their study, published in ...
Jul 24, 2026
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New treatment approach improves survival, reduces recurrence risk in muscle-invasive bladder cancer
Researchers have found that a combination of enfortumab vedotin and pembrolizumab helps patients with muscle-invasive bladder cancer live longer while reducing the risk that their cancer will return after surgery, according ...
Jul 24, 2026
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Inherited gene variants may shape CAR-T therapy benefits and toxic side effects
Chimeric antigen receptor (CAR)-T cell therapy, which reprograms an individual's immune cells to seek out and destroy certain cancer cells, has revolutionized treatment for blood cancers such as lymphoma. But in some patients, ...
Jul 24, 2026
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Scientists develop more photostable near-infrared fluorescent dye for longer surgical imaging
Researchers in Korea have developed a new near-infrared (NIR) fluorescent dye with significantly improved photostability, overcoming the rapid signal fading that has long limited fluorescence imaging during surgery for cancer, ...
Jul 24, 2026
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Ancient molecule made inside tumors drives immune response, study finds
An ancient molecule that existed long before the circulatory system evolved has been found to support cancer immunotherapy. Researchers at Nagoya University in Japan found that complement C3 protein acts inside tumors to ...
Jul 23, 2026
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Brain cancer map uncovers thousands of hidden targets for personalized immunotherapies
Researchers from the Clinical Neuroscience Consortium (CNC), a collaborative platform jointly established by the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and Queen Mary Hospital, in collaboration with ...
Jul 23, 2026
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Premature blood stem cell aging in sickle cell disease may be reversible
Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital. Patients with sickle ...
Jul 23, 2026
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New immune mechanism helps explain why ovarian cancer stops responding to chemotherapy
Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer so lethal. In a new study published in The Journal for ImmunoTherapy of Cancer, the researchers ...
Jul 23, 2026
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New strategy could prevent T cell exhaustion and boost immunotherapy
A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors. But this strategy has been undermined by the tendency of T cells to tire out before finishing ...
Jul 23, 2026
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Chemotherapy leaves detectable DNA fingerprints in childhood tumors within 18 months
Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). ...
Jul 23, 2026
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