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Oncology news
New strategy intercepts pancreatic cancer by eliminating microscopic lesions before they become cancer
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors. Using an experimental therapy to target microscopic precancerous lesions in the ...
9 hours ago
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First-of-its-kind analysis reveals the structural variant landscape driving pediatric cancer development
The first and largest dataset of genomic structure variations specific to childhood cancers was published today by scientists from St. Jude Children's Research Hospital and the National Cancer Institute. The researchers assembled ...
10 hours ago
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Tuning T cells' cancer-killing power via an engineered hydrogel platform
Lymph nodes, considered the command centers of our immune system, often get swollen and stiff when fighting infection. Now, a UC Berkeley-led team of researchers has discovered that this mechanical change may help instruct ...
10 hours ago
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Scientists find a new therapeutic target present on up to half of all tumors
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden ...
12 hours ago
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Trial finds immunotherapy did not improve survival when added to chemoradiotherapy for small cell lung cancer
Immunotherapy given during and after chemoradiation did not improve survival for study participants with limited-stage, small-cell lung cancer (SCLC) according to the results of an international clinical trial, NRG-LU005, ...
4 hours ago
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Romiplostim prevents serious side effect of chemotherapy in phase 3 trial
Results from a global phase 3 clinical trial led by investigators at Mass General Brigham show that the medication romiplostim can effectively prevent chemotherapy from destroying platelet-producing bone marrow cells, a common ...
8 hours ago
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New atlas that charts tumor cell diversity could guide personalized therapy for head and neck cancer
Head and neck squamous cell carcinomas (HNSCC) are the seventh-most prevalent form of cancer and are associated with human papilloma virus infection (HPV-positive) or with tobacco and alcohol use (HPV-negative). HPV-negative ...
8 hours ago
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Novel tool measures how cancer cells rewrite genetic instructions to aid growth and survival
Cancer is caused by faulty genes, but what also shapes a cancer cell's behavior is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive. A study published in ...
21 hours ago
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Personalized support program improves smoking cessation for cervical cancer survivors
A new study led by UCLA researchers suggests that a personalized counseling program can significantly help women who have survived cervical precancer or cervical cancer to quit smoking—and does so at a cost that researchers ...
15 hours ago
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Prostate cancer deaths to decrease, researchers predict
Prostate cancer is one of the leading causes of cancer-related death in men, and some experts project the number of cases to rise over the coming decades. But in a recent Urologic Oncology article, Yale School of Medicine ...
9 hours ago
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Higher burnout rates among physicians who treat sickle cell disease
Hematology-oncology-trained physicians who treat sickle cell disease reported higher rates of burnout (60%) than their counterparts who do not provide sickle cell care (43%) despite no differences in grit and resilience between ...
16 hours ago
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Structured exercise programs may help combat 'chemo brain' according to new study
New research suggests that exercise may help people with cancer stay mentally sharp and better able to handle daily tasks, work, and social activities through chemotherapy treatment delivered on an every two-week cycle. This ...
17 hours ago
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Severe COVID-19 and flu can facilitate lung cancer months or years later
Severe COVID-19 and influenza infections prime the lungs for cancer and can accelerate the disease's development, but vaccination heads off those harmful effects, new research from UVA Health's Beirne B. Carter Center for ...
Mar 11, 2026
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Experimental chemo drug triggers 'viral mimicry' signals that rally immune attack
In recent years, scientists have discovered that some chemotherapy drugs not only kill cancer cells directly, but at least in some patients, mysteriously also trigger their immune system to attack the cancer. That would seem ...
Mar 11, 2026
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Unusual tumor cells may be overlooked factors in advanced breast cancer
An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, according to a study led by investigators at Weill Cornell Medicine ...
Mar 11, 2026
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Distinct tumor 'neighborhoods' could guide more targeted treatments in aggressive childhood brain cancer
New research published in Nature finds that tumor cells within supratentorial ependymomas (SE)—an aggressive childhood brain cancer—cluster into distinct tumor cell populations. Much like a neighborhood, each cell subtype ...
Mar 11, 2026
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Aging may change lung cancer treatment: Targeting ATF4 could curb metastasis
Researchers at the University of Gothenburg have identified a protein linked to an increased risk of metastasis and recurrence in lung cancer. The findings are presented in a study published in the journal Nature that paves ...
Mar 11, 2026
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New cancer therapies target epigenetic switch
Cancers emerge from many different paths. One path begins early, in embryonic development, when a protein complex called PRC2, which regulates cell differentiation, identity, and plasticity, becomes dysfunctional. PRC2 has ...
Mar 11, 2026
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Turning cancer's protein machinery against itself to boost immunity
A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response. Researchers ...
Mar 11, 2026
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Breast cancer stage at diagnosis differs sharply across rural US regions
Where a woman lives significantly affects whether her breast cancer is diagnosed at an early or late stage, according to a national analysis published in the Journal of the American College of Surgeons (JACS). Researchers ...
Mar 11, 2026
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Optical genome mapping detects additional genetic variants in nearly 20% of individuals with acute leukemia
New research assessing the efficacy of optical genome mapping (OGM) in a group of patients with acute leukemia has demonstrated that OGM provided reliable and robust analytical performance with high sensitivity and specificity ...
Mar 11, 2026
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IVF not linked to higher overall cancer rates, but study shows differences in some cancers
Women who used fertility treatments had no higher overall risk of invasive cancer than other women, a large Australian study led by researchers from UNSW Sydney has found. The study, published in JAMA Network Open, analyzed ...
Mar 10, 2026
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Scientists develop two-vaccine strategy to fight T cell lymphoma
T cell lymphomas are notoriously difficult to treat because immunotherapy, despite being one of the most effective therapies for treating cancer, can't easily distinguish cancerous T cells from healthy ones. Now, scientists ...
Mar 10, 2026
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Common p53 genetic mutation reveals Achilles' heel in lung cancer
A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA replication in cancer ...
Mar 10, 2026
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Google AI rivals radiologists in breast cancer detection
New research on 175,000 women—the largest NHS study to date—on the use of AI in breast cancer screening shows that AI detected more cases of invasive cancer, more cases overall, had fewer false positives, and recalled ...
Mar 10, 2026
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