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Oncology news
A liquid biopsy blood test may improve children's survival of cancer in Africa
In a study published in Nature Medicine, researchers from the University of Oxford and the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es Salaam, Tanzania have shown that a minimally invasive liquid ...
2 hours ago
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Combination treatment benefits patients with advanced breast cancer that has spread to the brain
Patients with leptomeningeal metastasis (LM) have historically had few treatment options. Now, researchers from The University of Texas MD Anderson Cancer Center have found a combination of targeted therapies, tucatinib and ...
16 hours ago
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Scientists create cancer-fighting immune cells right in the body
For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an elaborate process: Doctors extract a patient's immune cells, ship them to a specialized facility where ...
20 hours ago
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Antioxidant serves as an unexpected food source for tumors, scientists discover
Researchers have discovered an antioxidant, glutathione, that cancer cells appear to be "addicted to" as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient.
20 hours ago
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Long dismissed in adult health, the thymus may be critical for longevity and cancer treatment
Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant in adulthood. ...
20 hours ago
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Cholecystokinin, not insulin, may be key hormone in obesity-driven pancreatic cancer
Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels. Scientists have thought that this excessive insulin secretion ...
19 hours ago
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Cellular stress signal found to drive immune exhaustion and weaken cancer therapy
Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress ...
20 hours ago
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Why some breast cancers spread faster: Jagged1 may trigger a tissue-stiffening feedback loop
A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor tissue during breast cancer ...
14 hours ago
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Cancer drug protein target may also help fight influenza
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX). Published in Cell Reports, the study found that Programmed Death-Ligand ...
14 hours ago
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Novel X-ray technique could transform tissue diagnosis
A new X-ray imaging technique could transform how hospitals analyze tissue samples, potentially speeding up diagnoses and improving outcomes for patients, shows a new study led by UCL researchers. The technology, developed ...
15 hours ago
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Perfluorooctanesulfonic acid, perfluoroheptanoic acid, mono-iso-nonyl-phthalate can predict lung cancer mortality
A model composed of perfluorooctanesulfonic acid (PFOS), perfluoroheptanoic acid (PFHA), and the plasticizer mono-iso-nonyl-phthalate can predict lung cancer mortality, according to a study published online March 4 in Clinical ...
10 hours ago
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HPV vaccination protects girls living with HIV in South Africa, study shows
New research shows first population-level evidence globally that a national HPV vaccination program can be highly effective in a high HIV-prevalence setting. In South Africa, where the burden of HIV remains high, women living ...
19 hours ago
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Understanding the role of the protein PAX3 in cancer development
Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression. While progress ...
15 hours ago
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Cancer research at a crossroads: Experts warn against funding cuts and misinformation
A new editorial published in JAMA Oncology warns that cancer care progress is under threat from a trifecta of challenges: proposed federal budget cuts, a surge in medical misinformation, and a critical gap in public health ...
17 hours ago
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Surgery plays a central role in treatment for colorectal cancer—and is usually the first step
When someone is diagnosed with colorectal cancer—which includes both colon and rectal cancers—many people immediately think "surgery." And it's true that surgery plays a central role in treatment for most patients. But ...
18 hours ago
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Study identifies inflammatory immune pathway driving immunotherapy resistance in bladder cancer
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy. Their ...
20 hours ago
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New study identifies how obesity-related liver cancer becomes more aggressive and resistant to treatment
A research team affiliated with UNIST has made a significant discovery explaining why liver cancers associated with obesity and metabolic disorders tend to be more aggressive and less responsive to conventional treatments. ...
23 hours ago
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Brain tumors hijack sugar metabolism to evade immune attack, study shows
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published in the Proceedings ...
Mar 17, 2026
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Hidden drug reservoirs in cancer cells could explain treatment resistance
One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in Nature Communications, by a multidisciplinary team led by Dr. Louise Fets ...
Mar 17, 2026
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Implantable 'charging station' boosts fight against cancer
Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease. But many engineered immune cells lose strength quickly after they enter the body, especially inside tumors that actively ...
Mar 17, 2026
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'Junk DNA' may help defend against colorectal cancer
For decades, large portions of the human genome were labeled "junk DNA." New research from Western University and London Health Sciences Centre Research Institute (LHSCRI) suggests these overlooked sequences may help protect ...
Mar 17, 2026
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Promising new therapy developed for most common form of bone cancer in children and young adults
Finding an effective treatment for osteosarcoma, the most common type of bone cancer in children and young adults, has puzzled medical researchers for 40 years. Now, a new study by researchers at Case Western Reserve University ...
Mar 17, 2026
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Research uncovers the dual role of ezrin, a protein driving bone cancer in children
Scientists at Georgetown University's Lombardi Comprehensive Cancer Center have uncovered a new dual function for a well-known cancer-related protein called ezrin. This finding could potentially open the door to new treatments ...
Mar 17, 2026
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Engineered bacteria deliver cancer drug directly inside tumors in mice
Every year, millions of people are diagnosed with cancer globally; however, current treatments are limited by disease complexity. A study published in the open-access journal in PLOS Biology by Tianyu Jiang at Shandong University, ...
Mar 17, 2026
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Blocking lipid production in healthy lung cells can reduce lung metastasis
KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, has discovered how cancer cells can exploit healthy lung cells to support metastatic tumor growth in the lungs. In two complementary ...
Mar 17, 2026
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