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Oncology news
Giving antibodies 'eyes' may help target hidden KRAS mutations in cancer cells
Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have remained a "blind spot" for treatment because antibodies cannot reach them. KAIST researchers have now ...
11 hours ago
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New mechanoresistant cancer cells show how they survive high stress environments
When a cancer cell leaves the original tumor to spread to a new, faraway location, it first has to survive what most cells cannot: periodic high-force moments in the vessels and heart of up to 5,000 dynes per centimeter squared ...
11 hours ago
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Inherited gene variants may shape CAR-T therapy benefits and toxic side effects
Chimeric antigen receptor (CAR)-T cell therapy, which reprograms an individual's immune cells to seek out and destroy certain cancer cells, has revolutionized treatment for blood cancers such as lymphoma. But in some patients, ...
10 hours ago
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Redesigned lung cancer drug matches tumor control with fewer off-target interactions
Researchers at Moffitt Cancer Center have developed a new chemical approach that could help make targeted cancer medicines safer and more precise. The discovery gives scientists a new way to design drugs that bind more selectively ...
9 hours ago
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Tiny BAP1 mutations can disrupt internal signals that suppress tumor growth
Scientists at the Institute of Biochemical Sciences at National Taiwan University have uncovered how tiny genetic changes can disable one of the body's most important tumor-suppressing proteins. Their study, published in ...
10 hours ago
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Scientists develop more photostable near-infrared fluorescent dye for longer surgical imaging
Researchers in Korea have developed a new near-infrared (NIR) fluorescent dye with significantly improved photostability, overcoming the rapid signal fading that has long limited fluorescence imaging during surgery for cancer, ...
10 hours ago
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New treatment approach improves survival, reduces recurrence risk in muscle-invasive bladder cancer
Researchers have found that a combination of enfortumab vedotin and pembrolizumab helps patients with muscle-invasive bladder cancer live longer while reducing the risk that their cancer will return after surgery, according ...
12 hours ago
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Brain cancer map uncovers thousands of hidden targets for personalized immunotherapies
Researchers from the Clinical Neuroscience Consortium (CNC), a collaborative platform jointly established by the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and Queen Mary Hospital, in collaboration with ...
Jul 23, 2026
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Ancient molecule made inside tumors drives immune response, study finds
An ancient molecule that existed long before the circulatory system evolved has been found to support cancer immunotherapy. Researchers at Nagoya University in Japan found that complement C3 protein acts inside tumors to ...
Jul 23, 2026
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Premature blood stem cell aging in sickle cell disease may be reversible
Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital. Patients with sickle ...
Jul 23, 2026
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New immune mechanism helps explain why ovarian cancer stops responding to chemotherapy
Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer so lethal. In a new study published in The Journal for ImmunoTherapy of Cancer, the researchers ...
Jul 23, 2026
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New strategy could prevent T cell exhaustion and boost immunotherapy
A major pillar of cancer immunotherapy involves stimulating T cells, the specialized killers of the immune system, to attack tumors. But this strategy has been undermined by the tendency of T cells to tire out before finishing ...
Jul 23, 2026
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Chemotherapy leaves detectable DNA fingerprints in childhood tumors within 18 months
Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids). ...
Jul 23, 2026
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How systemic immune regulation is 'hijacked' during tumor progression
The immune system plays a critical role in protecting the body from cancer by recognizing and eliminating abnormal cells before they can develop into tumors. This process relies on T cells that can recognize tumor-derived ...
Jul 23, 2026
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Mass-producible immune cells kill patient-derived colorectal tumors in mice
Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted in mice. The Kobe University development is a significant contribution toward faster, cheaper cancer immunotherapy.
Jul 23, 2026
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Social inequalities shape childhood mortality from leukemia in Brazil
Why do children with lymphoid leukemia face markedly different mortality rates depending on where they live in Brazil? In a collaboration between researchers at LMU and the Federal University of Rio de Janeiro (UFRJ), trends ...
Jul 23, 2026
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Focused ultrasound may enhance chemotherapy, survival outcomes for pancreatic cancer
A phase 2 clinical trial published in the European Journal of Cancer suggests that a novel form of focused ultrasound combined with standard FOLFIRINOX chemotherapy may improve tumor response and survival outcomes in patients ...
Jul 23, 2026
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Colorectal cancer isn't the only gastrointestinal cancer rising in young adults
You may have heard that colorectal cancer is increasingly affecting young adults. However, it is not the only gastrointestinal (GI) cancer that doctors are diagnosing in patients below the age of 50, explains Christina Wu, ...
Jul 23, 2026
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Test offers new way to personalize treatment, reduce unnecessary chemotherapy for patients with breast cancer
A new cancer diagnostic test marketed by Veracyte and developed by a group of researchers, including UNC geneticist Charles Perou, Ph.D., has been found to accurately predict whether patients with breast cancer need chemotherapy ...
Jul 23, 2026
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RNA testing uncovers 171 mutations driving MET exon 14 skipping in lung cancer
New research has shown that RNA-based testing can improve the detection and interpretation of clinically actionable genomic alterations that lead to MET exon 14 skipping in patients with lung cancer—important biomarkers that ...
Jul 23, 2026
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Natural compounds against sarcoma: Which one shows the greatest potential?
Curcumin, berberine and other plant-derived compounds have long attracted scientific interest because of their anti-inflammatory and anticancer properties. A new study by researchers from Wroclaw Medical University and the ...
Jul 22, 2026
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Brain-penetrating nanoparticles, ultrasound and microbubbles show promise in treating glioblastoma
University of Virginia Comprehensive Cancer Center scientists have developed a promising new experimental approach to targeting glioblastoma, the most common and deadliest brain cancer. The approach could overcome many of ...
Jul 22, 2026
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Same carcinogen, different tumors: Mouse study reveals the role of genetic background
Why do cancers develop differently in different people—even when they are exposed to the same risk factors? An international research group, including the German Cancer Research Center (DKFZ), has demonstrated in mice that ...
Jul 22, 2026
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New therapeutic target expands options for multiple myeloma
In a phase 1 clinical trial, treatment with the investigational bispecific antibody cevostamab reduced cancer in more than 40% of patients with multiple myeloma, many of whom had already undergone multiple other cancer treatments, ...
Jul 22, 2026
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Two cellular components unlock maturation in human leukemia cells, study finds
In leukemia's most aggressive forms, the blood cell factories in our bone marrow falter. Instead of dividing and multiplying at their usual prolific pace, generating hundreds of billions of new cells daily, some precursor ...
Jul 22, 2026
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