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Oncology & Cancer news

Oncology & Cancer

AI model predicts B cell reactivity to neoantigens for improved cancer vaccines

Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move beyond one-time attacks and short-term memory to become a long-term immunity that "remembers" cancer, ...

Oncology & Cancer

Tumor bacteria linked to immunotherapy resistance in head and neck cancer

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

Oncology & Cancer

Study finds a better way to screen for breast cancer

A pioneering study has found that an individualized approach to breast cancer screening that assesses patients' risk, rather than annual mammograms, can lower the chance of more advanced cancers, while still safely match ...

Oncology & Cancer

How stomach cancer learns to grow on its own

Gastric (stomach) cancer remains one of the most common and deadly cancers in East Asia, including Korea. Yet despite its high prevalence, it has received far less molecular attention than colorectal cancer, which is more ...

Oncology & Cancer

Stiffer colon could signal risk of early-onset colorectal cancer

Increased stiffness of the colon, spurred by chronic inflammation, may encourage the development and progression of early-onset colorectal cancer (CRC), a study co-led by UT Southwestern Medical Center researchers suggests. ...

Oncology & Cancer

Inflammation fuels one of the most aggressive forms of lung cancer

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only 5%. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy. However, patients ...

Oncology & Cancer

Protein MCL1 links cancer cell survival and energy metabolism

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology. Published in Nature Communications, the study shows for ...

Oncology & Cancer

How brain tumor cells influence neurons and vice versa

Gliomas are cancers that originate directly in the brain, instead of spreading to the brain from other parts of the body. These cancers cannot be cured with conventional cancer treatments, as they spread into healthy brain ...

Medications

Calcium-sensitive switch boosts the efficacy of cancer drugs

Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don't make it that far. A new study shows how this Trojan Horse strategy works better by exploiting ...

Oncology & Cancer

Tattoos could be a risk factor for melanoma

An increasing number of Swedes are getting tattoos and Sweden's population is now one of the most tattooed in Europe. At the same time, the incidence of melanoma is increasing. A new epidemiological study from Lund University ...

Oncology & Cancer

Higher glycemic index linked to higher lung cancer risk

In a study appearing in The Annals of Family Medicine, researchers examined whether people who follow higher-GI or higher-GL diets have different risks of developing lung cancer. They used data from 101,732 adults in the ...

Medical research

Advancing patient-reported outcomes in cancer clinical trials

The SISAQOL-IMI consortium, co-led by the European Organization for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has published a paper in The Lancet Oncology outlining how its recommendations for ...

Oncology & Cancer

How brain tumors respond to low-nutrient environments

A new study led by Peter Mac Professor Louise Cheng on fruit-fly brains has uncovered how cells that form the brain's protective barrier can act as "gatekeepers" and slow down the growth of some brain tumors.