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Oncology & Cancer news
Oncology & Cancer
Study identifies candidates for therapeutic targets in pediatric germ cell tumors
A study conducted by the Molecular Oncology Research Center (CPOM) at Hospital de Amor in Barretos (formerly Barretos Cancer Hospital) in the state of São Paulo, Brazil, has identified possible biomarkers that could guide ...
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Oncology & Cancer
Scientists identify dual protein targets to weaken pancreatic cancer defenses
Indiana University School of Medicine scientists have identified a new way to weaken pancreatic cancer's defenses by targeting two key proteins that help the deadly disease resist treatment. The study, recently published ...
13 hours ago
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Dietary supplement found effective for skin cancer prevention
The dietary supplement nicotinamide has been recommended by dermatologists for people with a history of skin cancer since 2015, when a clinical study with 386 participants showed that those who took the vitamin B3 derivative ...
16 hours ago
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Study finds 10% of pediatric blood cancers may stem from medical imaging radiation
A study led by UC San Francisco and UC Davis has concluded that radiation from medical imaging is associated with a higher risk of blood cancers in children.
16 hours ago
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New insights into melanoma plasticity uncover a critical role of iron metabolism
VIB researchers and colleagues have discovered a mechanism through which melanoma cells adapt and switch between two major proliferative and invasive states, revealing promising new targets for cancer therapy.
15 hours ago
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Age 70 identified as cutoff for chemotherapy benefit in colorectal cancer
Colorectal cancer remains a leading cause of cancer death, with incidence rising among older adults. One of the most pressing clinical questions has been whether elderly patients should receive oxaliplatin, a standard component ...
17 hours ago
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Certain oral microbes tied to increased risk of pancreatic cancer
Twenty-seven species of bacteria and fungi among the hundreds that live in people's mouths have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, a study led by NYU Langone Health and its ...
17 hours ago
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Glioblastoma cells can 'unstick' from their neighbors to become more deadly
A new study, led by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, captured details of glioblastoma that had never before been seen and revealed a surprise ...
17 hours ago
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Digital cell twin opens up new avenues in lung cancer research
A team led by Christian Baumgartner of the Institute of Health Care Engineering at Graz University of Technology (TU Graz) has developed a highly detailed digital twin of the A549 lung cancer cell line. The twin builds on ...
18 hours ago
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Q&A: Combination therapy shows promise for overcoming treatment resistance in glioblastoma
Rakesh Jain, Ph.D., director of the Edwin Steele Laboratories for Tumor Biology in the Department of Radiation Oncology at Massachusetts General Hospital and Andrew Werk Professor of Radiation Oncology at Harvard Medical ...
12 hours ago
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Nonadherence to cervical cancer screening increased after COVID-19 pandemic
Nonadherence to cervical cancer screening in the United States increased after the COVID-19 pandemic, according to a study published online Sept. 10 in PLOS Global Public Health.
15 hours ago
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Lymph nodes found to be key to successful cancer immunotherapy
A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against ...
Sep 17, 2025
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Investigating how tumor-immune cell clusters drive breast cancer spread
In a pair of studies, investigators from the lab of Huiping Liu, MD, Ph.D., associate professor of Pharmacology and of Medicine in the Division of Hematology and Oncology, have uncovered how specific cellular interactions ...
Sep 17, 2025
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Scientists find cell surface sugar that slows pancreatic cancer in mice—and it's detectable in patient blood samples
Pancreatic cancer has the highest mortality rate of all major cancers, and its incidence is climbing. Because it is typically asymptomatic at early stages, pancreatic cancer is especially difficult to catch and treat in time. ...
Sep 17, 2025
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Stronger together: A new fusion protein boosts cancer immunotherapy
A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein ...
Sep 17, 2025
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AI model indicates four out of ten breast cancer patients could avoid axillary surgery
A project at Lund University in Sweden has trained an AI model to identify breast cancer patients who could be spared from axillary surgery. The model analyzes previously unutilized information in mammograms and pinpoints ...
Sep 17, 2025
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Subtle cues between cells and immune system can contribute to spread of cancer
In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new colonies within the body. Blocking the cells' ability to follow the trail might halt metastasis but ...
Sep 17, 2025
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'Molecular glue' harnesses the power of the immune system to treat neuroblastoma
Gene expression governs whether neuroblastoma tumor cells exist in either the adrenergic (differentiated and sensitive to treatment) or mesenchymal (less differentiated and therapy-resistant) cell state. Tumors may switch ...
Sep 17, 2025
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Algorithm that predicts pancreatic cancer metastasis could help avoid unnecessary surgeries
Pancreatic cancer remains one of the biggest challenges in the field of oncology. Numbers of cases are increasing, and the latest personalized therapies and immunotherapy are not yet yielding results. Much of the effort is ...
Sep 17, 2025
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Blocking CNNM4 protein with RNA technology could treat rare and aggressive liver cancer
An international study led by Dr. Malu Martínez-Chantar, principal investigator at CIC bioGUNE and CIBERehd, has identified a new therapeutic target for cholangiocarcinoma (CCA), a rare but highly aggressive liver cancer ...
Sep 17, 2025
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Lactate-driven protein modification weakens natural killer cell cancer defenses
A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in collaboration with Prof. Ding Chen's team from Human Phenome Institute at Fudan University, has elucidated ...
Sep 17, 2025
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Reprogramming the epigenetic code affects growth and survival of tumor cells in multiple myeloma
In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of chemical "tags" on DNA and proteins that control whether genes are turned on or off. These "tags" affect ...
Sep 17, 2025
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Basal stem-like cells identified as origin of small cell lung cancer in lab models
A new study reveals that small cell lung cancer (SCLC) likely begins in basal stem-like cells rather than in neuroendocrine cells, marking a major shift in the understanding of this aggressive disease that is often associated ...
Sep 17, 2025
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NONO molecules block immune system defenses against breast cancer, so researchers switched it off
A new study has identified a potential new target for treating triple-negative breast cancer, one of the most aggressive forms of breast cancer, which still has very few therapeutic options available. The study was carried ...
Sep 17, 2025
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New personalized risk score could improve ovarian cancer detection
Researchers from Queen Mary University of London have developed and validated a new tool that could help GPs detect ovarian cancer earlier and improve patient outcomes cost-effectively.
Sep 17, 2025
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