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Oncology & Cancer news
Oncology & Cancer
Localized IL-12 delivery reshapes CAR-T safety in solid tumors
An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously ...
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Improving immunotherapy responses to fight cancer with dual therapies
Promising study in dual inhibition of PD1 and macrophage migration inhibitory factor
3 hours ago
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Scientists uncover new driver of ovarian cancer spread
Adelaide researchers have identified a promising new biomarker and treatment target for ovarian cancer that could markedly improve the outlook for women diagnosed with this aggressive disease.
2 hours ago
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BiTE-based immunotherapy strategy could point the way to a breakthrough for ovarian cancer patients
Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy—engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint ...
4 hours ago
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COVID-19 mRNA vaccines could unlock the next revolution in cancer treatment
The COVID-19 mRNA-based vaccines that saved 2.5 million lives globally during the pandemic could help spark the immune system to fight cancer. This is the surprising takeaway of a new study that we and our colleagues published ...
Oct 25, 2025
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Living tumor-on-a-chip exposes how cancers block immune attacks
For a little over two decades, chimeric antigen receptor (CAR) T cell therapy has emerged as a powerful new way to treat cancer. By extracting patients' T cells, re-engineering them to recognize tumor antigens, and infusing ...
Oct 24, 2025
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Key nervous system components shown to influence gastrointestinal tumor growth
Australian researchers have identified two nervous system components that drive tumor growth in gastrointestinal cancers, creating promising new avenues for treatment with existing approved therapies.
Oct 24, 2025
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Common jobs held by immigrant women may put them at increased risk of breast cancer
Many immigrant women in the U.S. work in jobs that may expose them to chemicals linked to breast cancer, according to a new study led by Silent Spring Institute. The study is among the first to examine how job-related chemical ...
Oct 24, 2025
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Medicaid expansion tied to smaller declines in early-stage cancer detection
During the COVID-19 pandemic, Medicaid expansion was associated with smaller declines in early-stage cancer detection, according to a study published online Oct. 21 in the Journal of the National Cancer Institute.
Oct 24, 2025
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Toward rapid and comprehensive genetic diagnosis of pediatric cancer through adaptive sequencing
What if a single test could simultaneously contribute to the diagnosis, characterization, and treatment guidance of childhood cancer—while helping avoid toxic or potentially unnecessary treatments?
Oct 24, 2025
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Immune-hot brain tumor subtype that defies survival expectations discovered
A research team has discovered a previously overlooked subtype of brain tumor termed IME IDH-mutant astrocytoma. Contrary to typical medical expectations, this subtype exhibits strong immune activity, classified as "immune‑hot," ...
Oct 23, 2025
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'Guided missile' drug molecule seeks out and destroys cancer's genetic lifeline
Researchers have created a new type of drug molecule that can precisely destroy TERRA, an RNA molecule that helps certain cancer cells survive. Using advanced "RIBOTAC" technology, their compound finds TERRA inside cells ...
Oct 23, 2025
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Experimental targeted therapy shows promise for histiocytosis, a rare blood cancer
The first time Joey Carlsen Martinez came to Memorial Sloan Kettering Cancer Center (MSK), he was in terrible shape. He had a rare blood cancer called Erdheim-Chester disease, and his symptoms included crushing fatigue, severe ...
Oct 23, 2025
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Major study examines endoscopies that fail to detect esophageal cancer
An endoscopy—using a fiber‐optic tube to peer inside the body and collect biopsy samples—can be an invaluable way to detect cancer of the esophagus. But sometimes, an endoscopy can miss esophageal cancer, which doesn't ...
Oct 23, 2025
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Novel drug combinations pave the way for personalized leukemia therapies
Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have published a review on BH3 mimetics—a new class of drugs that are reshaping the treatment landscape for acute myeloid ...
Oct 23, 2025
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Potential antibody therapy restricts the growth of aggressive and treatment-resistant breast cancers
A new potential antibody therapy strategy which restricts the growth of treatment-resistant breast cancers has been developed by scientists.
Oct 23, 2025
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Drug that stops tumors' blood supply could help kids with bone cancer live longer
Ewing sarcoma is one of the most common bone cancers seen in children, and if it spreads, it can be deadly. One study found that under a quarter of children with multi-metastatic Ewing sarcoma survived five years after their ...
Oct 23, 2025
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How a new light-based cancer treatment could destroy tumors without harming healthy cells—using LEDs
Cancer treatment has come a long way, but many of today's therapies still come with steep costs: not just financial, but physical and emotional too. Chemotherapy and radiotherapy remain vital tools, yet they often damage ...
Oct 23, 2025
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New drug study shows improved survival for early breast cancer
Mayo Clinic researchers collaborated on a new study led by Eli Lilly showing that the drug abemaciclib improves survival for people with high-risk, early-stage breast cancer.
Oct 23, 2025
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Can grape seed extract slow the growth of prostate cancer after treatment?
Grape seed extract—a dietary supplement made from the seeds of wine grapes—has been investigated to see if it can help reduce blood cholesterol levels and high blood pressure. But can it also help slow down the growth ...
Oct 23, 2025
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Researchers develop innovative vascularized tumor model to advance cancer immunotherapy
A research team led by the Faculty of Dentistry at The University of Hong Kong (HKU) has developed a novel vascularized tumor model using a non-surgical injectable hydrogel system. This innovative approach provides a powerful ...
Oct 23, 2025
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An understudied type of breast cancer poses a lurking threat
University of Colorado Cancer Center member Matthew Sikora, Ph.D., is a national leader in research into an understudied subtype of breast cancer that's on the rise in American women, is often more difficult to detect than ...
Oct 23, 2025
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Sentinel lymph node biopsy noninferior to lymphadenectomy in cervical cancer
For patients with early-stage cervical cancer, sentinel lymph node biopsy alone is noninferior to lymphadenectomy with respect to disease-free survival, according to a study published online Oct. 15 in the New England Journal ...
Oct 23, 2025
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Many patients learn they could have cancer in the emergency department
Abdominal and chest pain. Injuries. Breathing difficulty. Infections. Mental health emergencies. Those are some of the most common reasons why people go to the local emergency department.
Oct 23, 2025
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