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Oncology & Cancer news
Oncology & Cancer
Common medicines may influence CRISPR therapy outcomes and precision cancer treatment
In a new study, scientists at the Max Planck Institute for Evolutionary Anthropology in Leipzig analyzed the impact of more than 2,000 clinically approved drugs on DNA repair and CRISPR genome editing outcomes. They found ...
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Oncology & Cancer
Targeting B-cells may boost immunotherapy in liver cancer treatment
Scientists have identified a promising strategy to improve liver cancer immunotherapy: targeting B-cells. While immunotherapy has transformed cancer treatment by activating T-cells—a type of immune cell that fights cancerous ...
53 minutes ago
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Clinical trial of personalized cancer vaccine demonstrates feasibility, safety, immune activation
The first-in-human clinical phase I trial assessing the feasibility and safety of WDVAX, an immunostimulatory biomaterial-based cancer vaccine, in a cohort of 21 patients with stage 4 metastatic melanoma, was concluded with ...
20 minutes ago
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Proton beam therapy boosts throat cancer survival, study finds
Photon therapy offers strong outcomes in treating oropharyngeal cancers; however, some radiation can reach and damage nearby healthy tissue. The damage can lead to side effects that may be severe for some patients. In a new ...
1 hour ago
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Fertility gene helps glioblastoma tumors survive chemotherapy and return after treatment, researchers discover
Research by University of Sydney scientists has uncovered a mechanism that may explain why glioblastoma returns after treatment, offering new clues for future therapies which they will now investigate as part of an Australian ...
10 hours ago
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Cannabis derivatives could provide new ovarian cancer treatments
In the future, scientists could use drugs made from cannabis to fight ovarian cancer. A team of scientists testing the effects of two chemical compounds sourced from cannabis on ovarian cancer cells have found that both show ...
15 hours ago
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New guideline maps care for pregnant women with blood cancers
A new guideline from the American Society of Clinical Oncology (ASCO) offers clear, evidence-based direction for treating blood cancers during pregnancy and shows that many patients can safely receive timely cancer care without ...
5 hours ago
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Large-scale study provides real-world data on rare side effect of cancer immunotherapy
Researchers led by investigators at Mass General Brigham have published valuable information about a rare but serious complication of anti-cancer immunotherapy, providing the first large-scale description of its risk factors ...
Dec 14, 2025
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First patient in Arizona treated with new immune cell therapy
A patient with synovial sarcoma, a soft-tissue cancer that usually occurs in the large joints of the arms and legs, is the first in Arizona treated with a new immune cell therapy known as TECELRA at the HonorHealth Research ...
Dec 14, 2025
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Integrating anatomy and biology for a better pancreatic cancer prognosis
Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive nature and limited prognostic tools. While the traditional staging systems, such as the TNM classification, focus on anatomical ...
Dec 13, 2025
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Tanning beds mutate skin cells far beyond the reach of ordinary sunlight, study shows
Tanning bed use is tied to almost a three-fold increase in melanoma risk, and for the first time, scientists have shown how these devices cause melanoma-linked DNA damage across nearly the entire skin surface, reports a new ...
Dec 12, 2025
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Study shows IL-36 gamma 'armored' CAR T cells can eradicate solid tumors
A laboratory study out of Roswell Park Comprehensive Cancer Center outlines a new way to boost the effectiveness of chimeric antigen receptor (CAR) T-cell therapy in solid-tumor cancers, resulting in their eradication. Led ...
Dec 12, 2025
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New immunotherapy targets for glioblastoma identified by mapping cell interactions
Glioblastoma is the most common form of brain cancer in adults, and its consequences are usually quick and fatal. After receiving standard-of-care treatment (surgery followed by radiation and chemotherapy), fewer than half ...
Dec 12, 2025
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Mini-tumors combine synthetic and real cells to simulate immune responses
Normally, the immune system recognizes and eliminates abnormal cells. However, cancer cells can develop strategies to evade this control: they block defense mechanisms or send inhibitory signals. In this way, tumors can grow ...
Dec 12, 2025
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Adding antibody treatment to chemo boosts outcomes for children with rare cancer
Children with a rare form of cancer called neuroblastoma which hasn't responded to initial treatment or that has relapsed may benefit from adding antibody treatment to usual chemotherapy, according to new results from a clinical ...
Dec 12, 2025
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Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations, analysis suggests
Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited mutations in the BRCA1 or BRCA2 genes, according to the results of a matched prospective analysis presented ...
Dec 12, 2025
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Acupuncture may help improve perceived breast cancer-related cognitive difficulties over usual care
Real and sham acupuncture were more effective at improving breast cancer survivors' perceived cognitive impairment compared with usual care, while real acupuncture was superior to sham acupuncture in improving objective cognitive ...
Dec 12, 2025
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Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors
A mobile health (mHealth) intervention for adolescent and young adult breast cancer survivors that offered tailored support by monitoring electronic patient-reported outcomes (ePROs) significantly improved quality of life ...
Dec 12, 2025
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Proton therapy shows survival benefit in Phase III trial for patients with head and neck cancers
A study published in The Lancet showed a significant survival benefit for patients with oropharyngeal cancers who were treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).
Dec 11, 2025
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Tricking tumors into marking themselves for destruction with focused ultrasound
USC biomedical engineers have found a way to make a solid tumor paint a target on its own back in order to train the body's immune system to find and destroy it.
Dec 11, 2025
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Scientists uncover key driver of treatment-resistant cancer: Genome-scrambling enzyme points to new treatments
University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer ...
Dec 11, 2025
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Blocking collagen signaling boosts drug delivery in pancreatic cancer
Pancreatic cancer is one of the deadliest malignancies, with survival rates remaining dismally low despite major advances in oncology. One of the key reasons lies in the disease's unique fibrotic microenvironment—a dense, ...
Dec 11, 2025
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How CAR T-cell therapies target myeloma at the molecular level
In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR T-cell therapy may be considered. ...
Dec 11, 2025
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Phase I trial finds breast cancer vaccine triggers an immune response and is safe
Cleveland Clinic researchers are presenting final Phase I data from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.
Dec 11, 2025
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CAR-T therapy yields long-term survival for patients with lymphoma
A study published in the Journal of Clinical Oncology confirms that one of the first Food and Drug Administration-approved CAR-T cell therapies offers long-term survival and potential cures for adult patients with relapsed ...
Dec 11, 2025
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