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Oncology & Cancer news
Oncology & Cancer
Custom-designed protein receptors help T cells target solid tumors more effectively
Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer ...
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Oncology & Cancer
Making cancer vaccines more personal
In a new study, University of Arizona researchers created a model for cutaneous squamous cell carcinoma, a type of skin cancer, and identified two mutated tumor proteins, or neoantigens, that contain features of good candidates ...
27 minutes ago
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Outdoor air pollution linked to higher incidence of breast cancer
Women living in parts of the United States with lower air quality, especially neighborhoods with heavy emissions from motor vehicles, are more likely to develop breast cancer, according to a multiyear analysis involving more ...
48 minutes ago
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Potential cancer outcome differences among psoriasis biologics found
Copenhagen University Hospital–Herlev and Gentofte led a nationwide registry study that the authors claim shows a "pattern suggesting" a lower five-year risk of any first cancer (excluding non-melanoma skin cancer) with ...
Localized IL-12 delivery reshapes CAR-T safety in solid tumors
An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously ...
A 'mirror' amino acid selectively impairs growth of certain tumors
Researchers from UNIGE and Marburg show that D-cysteine, the "mirror" form of cysteine, selectively targets certain cancer cells.
14 hours ago
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Uncovering new therapeutic targets for a common KRAS mutation behind cancer
A team of Northwestern investigators has discovered novel molecular underpinnings of a common oncogenic mutation in cancer, findings that may inform the development of new therapeutic strategies, according to findings published ...
13 hours ago
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Up to 5% of Americans carry genetic mutations associated with cancer risk
New Cleveland Clinic research reveals that up to 5% of Americans—approximately 17 million people—carry genetic mutations or "variants" linked to increased cancer susceptibility, regardless of risk factors like personal ...
14 hours ago
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Breastfeeding linked to lasting immune protection against breast cancer
A team of researchers led by Peter Mac's Professor Sherene Loi has uncovered how having children and breastfeeding reduces a woman's long-term risk of breast cancer.
17 hours ago
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Some cancer patients get heart damage during chemotherapy and some don't: Here's why
Sometimes the unintended consequences of a treatment can seem worse than the disease. That's certainly the case for patients who develop chemotherapy-induced cardiotoxicity—a severe side-effect that can lead to heart failure ...
18 hours ago
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Common cholesterol drug might protect against 'chemo brain'
The most common cholesterol drug around might help protect cancer patients from "chemo brain."
20 hours ago
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Scientists uncover new driver of ovarian cancer spread
Adelaide researchers have identified a promising new biomarker and treatment target for ovarian cancer that could markedly improve the outlook for women diagnosed with this aggressive disease.
20 hours ago
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Improving immunotherapy responses to fight cancer with dual therapies
Promising study in dual inhibition of PD1 and macrophage migration inhibitory factor
22 hours ago
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Promising new drug combination for melanoma patients resistant to treatment
Melanoma is the most common form of skin cancer, but for patients with advanced melanoma who no longer respond to standard immunotherapy, treatment options are painfully limited. Vanderbilt researchers led by Professor Emerita ...
15 hours ago
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'Sleep ALL night' program helps children with leukemia sleep better during treatment
Disrupted sleep is a common, often overlooked problem for pediatric patients being treated for acute lymphoblastic leukemia (ALL). To address this issue, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders ...
15 hours ago
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Why fasting won't cleanse your body—or beat cancer
Every few months, a new "miracle cure" for cancer trends on social media. From superfoods and supplements to extreme diets, the promises are always bold—and almost always misleading. The latest claim suggests that a 21-day ...
18 hours ago
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BiTE-based immunotherapy strategy could point the way to a breakthrough for ovarian cancer patients
Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy—engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint ...
22 hours ago
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COVID-19 mRNA vaccines could unlock the next revolution in cancer treatment
The COVID-19 mRNA-based vaccines that saved 2.5 million lives globally during the pandemic could help spark the immune system to fight cancer. This is the surprising takeaway of a new study that we and our colleagues published ...
Oct 25, 2025
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Living tumor-on-a-chip exposes how cancers block immune attacks
For a little over two decades, chimeric antigen receptor (CAR) T cell therapy has emerged as a powerful new way to treat cancer. By extracting patients' T cells, re-engineering them to recognize tumor antigens, and infusing ...
Oct 24, 2025
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Key nervous system components shown to influence gastrointestinal tumor growth
Australian researchers have identified two nervous system components that drive tumor growth in gastrointestinal cancers, creating promising new avenues for treatment with existing approved therapies.
Oct 24, 2025
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Common jobs held by immigrant women may put them at increased risk of breast cancer
Many immigrant women in the U.S. work in jobs that may expose them to chemicals linked to breast cancer, according to a new study led by Silent Spring Institute. The study is among the first to examine how job-related chemical ...
Oct 24, 2025
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Medicaid expansion tied to smaller declines in early-stage cancer detection
During the COVID-19 pandemic, Medicaid expansion was associated with smaller declines in early-stage cancer detection, according to a study published online Oct. 21 in the Journal of the National Cancer Institute.
Oct 24, 2025
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Toward rapid and comprehensive genetic diagnosis of pediatric cancer through adaptive sequencing
What if a single test could simultaneously contribute to the diagnosis, characterization, and treatment guidance of childhood cancer—while helping avoid toxic or potentially unnecessary treatments?
Oct 24, 2025
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Immune-hot brain tumor subtype that defies survival expectations discovered
A research team has discovered a previously overlooked subtype of brain tumor termed IME IDH-mutant astrocytoma. Contrary to typical medical expectations, this subtype exhibits strong immune activity, classified as "immune‑hot," ...
Oct 23, 2025
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'Guided missile' drug molecule seeks out and destroys cancer's genetic lifeline
Researchers have created a new type of drug molecule that can precisely destroy TERRA, an RNA molecule that helps certain cancer cells survive. Using advanced "RIBOTAC" technology, their compound finds TERRA inside cells ...
Oct 23, 2025
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