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Oncology & Cancer news
Oncology & Cancer
Inhibiting a problematic protein helps immunotherapies, CAR T-cell therapy to fight off melanoma more effectively
Melanoma, the deadliest form of skin cancer, can't always be removed with a scalpel.
3 hours ago
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Oncology & Cancer
Discovery of breast cancer treatment resistance mechanism could lead to new hope for some
Mayo Clinic researchers have discovered a key reason why certain breast cancers might not respond to an important new class of therapeutics called antibody drug conjugates (ADCs). These treatments pair an antibody that targets ...
10 hours ago
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Drugs approved for treating pain may also reduce bone cancer growth
Peripheral afferent neurons—nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord)—are known to infiltrate and grow within malignant bone tumors called osteosarcomas, ...
11 hours ago
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Custom-designed protein receptors help T cells target solid tumors more effectively
Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer ...
20 hours ago
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Protecting the gut after stem cell transplantation: New evidence uncovered for potential of microbiome-based therapies
Patients receiving intensive cancer treatments—such as radiation or stem cell transplantation—often suffer from severe damage to the intestinal lining. This not only causes pain and complications but also worsens long-term ...
14 hours ago
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AI models help pinpoint key neoantigens for personalized skin cancer vaccines
In a new study, University of Arizona researchers created a model for cutaneous squamous cell carcinoma, a type of skin cancer, and identified two mutated tumor proteins, or neoantigens, that contain features of good candidates ...
19 hours ago
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Study finds higher breast cancer rates in areas with more air pollution
Women living in parts of the United States with lower air quality, especially neighborhoods with heavy emissions from motor vehicles, are more likely to develop breast cancer, according to a multiyear analysis involving more ...
20 hours ago
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In-surgery radiation cuts pancreatic cancer return
Using targeted radiation during surgery—referred to as intraoperative radiation—to eliminate pancreatic cancer cells that have spread to areas around the pancreas, investigators at Johns Hopkins have been able to reduce ...
13 hours ago
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New study highlights need for coordinated approach to stomach cancer screening and prevention
Stomach cancer, or gastric cancer, is the third leading cause of cancer deaths worldwide, largely because most individuals are not diagnosed until after the cancer has progressed to a late stage.
14 hours ago
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AI tool identifies women at high risk of interval breast cancer
In a study of more than 100,000 screening mammograms, researchers demonstrated the potential of an AI tool to help identify women at higher risk of developing interval breast cancer, which is breast cancer that is diagnosed ...
16 hours ago
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Potential cancer outcome differences among psoriasis biologics found
Copenhagen University Hospital–Herlev and Gentofte led a nationwide registry study that the authors claim shows a "pattern suggesting" a lower five-year risk of any first cancer (excluding non-melanoma skin cancer) with ...
Localized IL-12 delivery reshapes CAR-T safety in solid tumors
An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously ...
A 'mirror' amino acid selectively impairs growth of certain tumors
Researchers from UNIGE and Marburg show that D-cysteine, the "mirror" form of cysteine, selectively targets certain cancer cells.
Oct 27, 2025
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Up to 5% of Americans carry genetic mutations associated with cancer risk
New Cleveland Clinic research reveals that up to 5% of Americans—approximately 17 million people—carry genetic mutations or "variants" linked to increased cancer susceptibility, regardless of risk factors like personal ...
Oct 27, 2025
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Uncovering new therapeutic targets for a common KRAS mutation behind cancer
A team of Northwestern investigators has discovered novel molecular underpinnings of a common oncogenic mutation in cancer, findings that may inform the development of new therapeutic strategies, according to findings published ...
Oct 27, 2025
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Breastfeeding linked to lasting immune protection against breast cancer
A team of researchers led by Peter Mac's Professor Sherene Loi has uncovered how having children and breastfeeding reduces a woman's long-term risk of breast cancer.
Oct 27, 2025
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Some cancer patients get heart damage during chemotherapy and some don't: Here's why
Sometimes the unintended consequences of a treatment can seem worse than the disease. That's certainly the case for patients who develop chemotherapy-induced cardiotoxicity—a severe side-effect that can lead to heart failure ...
Oct 27, 2025
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Common cholesterol drug might protect against 'chemo brain'
The most common cholesterol drug around might help protect cancer patients from "chemo brain."
Oct 27, 2025
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Scientists uncover new driver of ovarian cancer spread
Adelaide researchers have identified a promising new biomarker and treatment target for ovarian cancer that could markedly improve the outlook for women diagnosed with this aggressive disease.
Oct 27, 2025
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Improving immunotherapy responses to fight cancer with dual therapies
Promising study in dual inhibition of PD1 and macrophage migration inhibitory factor
Oct 27, 2025
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Promising new drug combination for melanoma patients resistant to treatment
Melanoma is the most common form of skin cancer, but for patients with advanced melanoma who no longer respond to standard immunotherapy, treatment options are painfully limited. Vanderbilt researchers led by Professor Emerita ...
Oct 27, 2025
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'Sleep ALL night' program helps children with leukemia sleep better during treatment
Disrupted sleep is a common, often overlooked problem for pediatric patients being treated for acute lymphoblastic leukemia (ALL). To address this issue, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders ...
Oct 27, 2025
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Why fasting won't cleanse your body—or beat cancer
Every few months, a new "miracle cure" for cancer trends on social media. From superfoods and supplements to extreme diets, the promises are always bold—and almost always misleading. The latest claim suggests that a 21-day ...
Oct 27, 2025
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BiTE-based immunotherapy strategy could point the way to a breakthrough for ovarian cancer patients
Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy—engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint ...
Oct 27, 2025
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COVID-19 mRNA vaccines could unlock the next revolution in cancer treatment
The COVID-19 mRNA-based vaccines that saved 2.5 million lives globally during the pandemic could help spark the immune system to fight cancer. This is the surprising takeaway of a new study that we and our colleagues published ...
Oct 25, 2025
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