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Oncology & Cancer news

Oncology & Cancer

Radiation therapy overcomes immunotherapy resistance in some cancers

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators ...

Oncology & Cancer

Key genes controlling brain tumor spread identified—may lead to new treatments

An international research team led from Uppsala University has identified new mechanisms behind how the aggressive brain tumor glioblastoma spreads in the brain. Targeting the identified connection between the tumor invasion ...

Oncology & Cancer

Novel complex induces immunogenic cancer cell death

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something ...

Oncology & Cancer

How metabolic chatter between cells undermines anti-tumor immunity

A Ludwig Cancer Research study has identified a complex chain of molecular chatter by which cancer cells, exploiting ordinary metabolic processes, program one set of noncancerous cells to manipulate another set of such cells ...

Oncology & Cancer

Genetic profiling of colorectal tumors across populations

Colorectal tumors can vary in molecular mutations among individuals and communities, according to a new study from Cedars-Sinai Cancer. Investigators reporting in the journal Cancer Research concluded that these differences ...

Oncology & Cancer

Origins of common lung cancer that affects smokers discovered

The "cell of origin" of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered in a new study in mice and humans by researchers at UCL, the Wellcome Sanger Institute and the ...

Oncology & Cancer

More men with prostate cancer are avoiding unnecessary surgery

Prostate cancer is a leading cause of cancer-related death among men in the United States. Despite this, widespread adoption of prostate cancer screening has been controversial. Many primary care doctors worry that screening ...

Oncology & Cancer

New research guides treatment regimen for aggressive blood cancer

Relapsed/refractory (R/R) mature T and natural killer (NK)-cell lymphomas (TNKL) are aggressive blood cancers often resistant to frontline therapies. A team of Mass General Brigham researchers found that patients with these ...

Oncology & Cancer

PBAF chromatin may explain melanoma spread to the brain

Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a dangerous form of skin cancer—spread to the brain. Their study, published in Molecular Cell, highlights ...