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Oncology & Cancer news

Oncology & Cancer

Scientists show targeting cancer stem cells can prevent gastric cancer recurrence

Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified the specific cells responsible for gastric cancer's tendency to return after treatment. The study also demonstrated that eliminating ...

Oncology & Cancer

Cancer's hidden 'safety switch': Silencing TAK1 gene could boost immunotherapy performance

Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.

Oncology & Cancer

New Raman imaging system detects subtle tumor signals

Researchers have developed a new compact Raman imaging system that is sensitive enough to differentiate between tumor and normal tissue. The system offers a promising route to earlier cancer detection and to making molecular ...

Oncology & Cancer

AI can help detect kidney cancer faster

Researchers have developed an AI-based tool that accelerates the detection of kidney cancer. Its effectiveness was validated in a study published in Communications Medicine.

Oncology & Cancer

Subtyping colorectal cancer may improve patient outcome predictions

Colorectal cancer, or CRC, is the world's second most lethal cancer based on the number of deaths, and is the third most prevalent malignant tumor. Doctors and patients have long been hoping for better diagnostics for prognosis, ...

Oncology & Cancer

WISDOM trial weighs risk-based cancer screening

University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based breast cancer screening and annual mammography. Rates of stage ≥IIB breast cancers met a noninferiority threshold under ...

Oncology & Cancer

Engineered dendritic cells boost cancer immunotherapy

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.

Oncology & Cancer

RNA-based molecule enhances therapies against pancreatic cancer

A research group at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has identified a candidate molecule that could improve current therapies against pancreatic cancer. The team designed the new molecule, ...

Oncology & Cancer

New risk score helps predict pancreatic cancer recurrence

Cedars-Sinai investigators, leading a multi-institutional team, have developed and validated a tool to predict which patients with pancreatic neuroendocrine tumors (PanNETs) need closer monitoring because their cancer is ...

Oncology & Cancer

How to reduce risk of lymphedema after head and neck cancer

Lymphedema after head and neck cancer is considerably more common than previously assumed and can persist long after cancer treatment has finished. Researchers at Lund University in Sweden have discovered that patients with ...

Oncology & Cancer

New technology reduces false positives in breast ultrasounds

New ultrasound technology developed at Johns Hopkins can distinguish fluid from solid breast masses with near perfect accuracy, an advance that could save patients, especially those with dense breast tissue, from unnecessary ...

Oncology & Cancer

Research links DNA replication failure to cancer therapy

A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals from RB tumor suppressor ...

Medical research

Microbial allies: Bacteria help fight against cancer

An international team of scientists led by researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and the University of Cologne have discovered that microbes associated with tumors produce a ...

Oncology & Cancer

Using deep learning for precision cancer therapy

Nearly 50 new cancer therapies are approved every year. This is good news. "But for patients and their treating physicians, it is becoming increasingly difficult to keep track and to select the treatment methods from which ...

Oncology & Cancer

AI matches dermatologists in assessing common skin cancer

A simple AI model has been shown to perform on a par with experienced dermatologists when assessing the aggressiveness of a common form of skin cancer, squamous cell carcinoma. The research was headed by the University of ...

Oncology & Cancer

Surprising new roles discovered for known blood cancer gene DNMT3A

A gene called DNMT3A is important for guiding blood stem cells into forming all the cell types present in blood, including red blood cells, white blood cells and platelets. When this gene accumulates mutations—which might ...

Oncology & Cancer

New treatments found for tough blood cancers

Researchers from King's have identified a new way to treat certain blood cancers using existing drugs, by turning a once-dismissed part of our DNA into a therapeutic target.

Medications

FDA approves Inlexzo for bladder cancer

The U.S. Food and Drug Administration has approved Inlexzo (gemcitabine intravesical system) for the treatment of patients with certain types of bladder cancer.

Oncology & Cancer

How small cell lung cancer hijacks neuronal synapses

An international research team has shown that lung cancer cells can form functional synapses with neurons, effectively hijacking the body's neural circuits to grow faster. The finding reveals a startling new dimension of ...

Oncology & Cancer

Repurposing a diabetes medication to prime CAR T cancer targets

Urothelial carcinoma (UC) is the second most common genitourinary cancer, leading to over 16,000 deaths a year in the United States. Despite recent advances, the 5-year survival rate for metastatic UC remains about 5% to ...