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Oncology & Cancer news
Oncology & Cancer
RNA-seq outperforms DNA methods in detecting actionable cancer mutations
Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq either fails, returns ...
8 hours ago
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Oncology & Cancer
AI-designed T cell receptor substitutes can accelerate precision cancer immunotherapy
New designer proteins created using an AI tool can selectively target peptide segments that bind to markers on diseased cancer cells, acting like molecular flags that signal immune cells to attack and destroy the threats.
6 hours ago
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Unmutated tumor antigens: Exploitable targets for immunotherapy
A team headed by Claude Perreault, Director of IRIC's Immunobiology Research Unit and Professor at the Faculty of Medicine at Université de Montréal, has identified novel tumor antigens that could lead to the development ...
6 hours ago
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Study finds sequencing treatments improves outcomes in head and neck cancer model
Head and neck squamous cell carcinomas (HNSCC) are a group of cancers that affect cells in and around our mouth and nose. With 890,000 new cases and 450,000 deaths annually, HNSCC accounts for roughly 4.5% of cancer diagnoses ...
9 hours ago
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Detecting cancer cells in blood: Microfluidic device captures cancer cells with 90% efficiency
Circulating tumor cells (CTCs) refer to cancer cells that have broken off from a primary tumor. These tumor cells can travel through the blood in the circulatory system and lodge themselves in other organs to cause secondary ...
3 hours ago
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Guideline on management of early-stage non-small cell lung cancer released
The American College of Chest Physicians (CHEST) recently released a new clinical guideline on the management of patients with early-stage non-small cell lung cancer (NSCLC). Published in the journal CHEST, the guideline ...
2 hours ago
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Immunotherapy alters bone marrow environment in acute myeloid leukemia patients
Scientists studying a hard-to-treat form of blood cancer called acute myeloid leukemia (AML) have found that a type of treatment—immunotherapy—may help change the environment where cancer cells live, possibly helping ...
6 hours ago
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Modulating the gut microbiome to power radiation therapy in lung cancer
In a randomized pilot study recently published in the Journal for ImmunoTherapy of Cancer, an international research team led by Andrea Facciabene, Ph.D., and Steven Joel Feigenberg, MD, both of the Department of Radiation ...
8 hours ago
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Blood tests show potential for colorectal cancer detection, but follow-up still falls short
A study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while blood-based tests offer a more convenient option for colorectal cancer screening, only 49% of patients completed a follow-up ...
4 hours ago
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AI catches one-third of interval breast cancers missed at screening
An AI algorithm for breast cancer screening has the potential to enhance the performance of digital breast tomosynthesis (DBT), reducing interval cancers by up to one-third, according to a study published today in Radiology.
5 hours ago
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Colon cancer and exercise: Can physical activity reprogram genes?
A new study led by researchers at Huntsman Cancer Institute at the University of Utah (the U) shows that regular exercise may do more than help colon cancer patients feel better—it may actually change gene activity in both ...
6 hours ago
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Most liver cancer cases are due to preventable risk factors, analysis suggests
The majority of liver cancer cases could be prevented by reducing levels of viral hepatitis, alcohol consumption and MASLD (metabolic dysfunction-associated steatotic liver disease—previously called non-alcoholic fatty ...
21 hours ago
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Study offers clearer picture of childhood brain tumor survival
Childhood brain tumor survival depends on the type of tumor. Comparing survival rates across countries is difficult, because brain tumors aren't recorded in the same way everywhere in Europe. A new study led by the Princess ...
21 hours ago
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Powering up T cells: A new path in cancer immunotherapy
Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer. By blocking a protein called Ant2, they were able to reprogram how these cells consume and generate energy—essentially ...
Jul 28, 2025
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Researcher uses light to target and kill cancer cells
A Northeastern University researcher has identified a way to target two of the deadliest cancer types, melanoma and triple negative breast cancer, with chemotherapy drugs but without the harms associated with chemotherapy.
Jul 28, 2025
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Olutasidenib found highly effective in certain patients with myelodysplastic syndrome
The targeted drug olutasidenib is highly effective in certain patients with myelodysplastic syndrome (MDS), a condition considered incurable without transplantation, according to a new clinical study led by researchers at ...
Jul 28, 2025
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New cyclic disulfide lipids help stop cancer growth in mice
Researchers at Nagoya University in Japan have developed a lipid nanoparticle that delivers mRNA to cells five times more effectively. By attaching a sulfur-containing ring structure—a cyclic disulfide—to lipid molecules, ...
Jul 28, 2025
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Study finds blocking minor splicing curbs tumor growth in multiple cancer types
Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by targeting a specialized molecular process known as "minor splicing."
Jul 28, 2025
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Prostate cancer explained: From antigen tests to treatment options
Prostate cancer is one of the most common cancers in the world. While many prostate cancers grow slowly and remain localized, other types are aggressive and spread quickly. That's why Dr. Carlos Vargas, a Mayo Clinic radiation ...
Jul 28, 2025
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Unlocking nature's toolkit: How plant compounds may support cancer therapy
Green tea and red wine may seem like simple dietary choices—but beneath the surface, they harbor compounds with remarkable medical potential. Scientists are uncovering how these everyday drinks might support cancer treatment, ...
Jul 28, 2025
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Patients face high out-of-pocket costs after incident cancer diagnosis
Patients face high out-of-pocket costs (OOPCs) after an incident diagnosis of cancer, with costs increasing with stage of diagnosis, according to a study published in JAMA Network Open.
Jul 28, 2025
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Insights into palliative care for patients with cancer
For patients with a cancer diagnosis, early specialty palliative care is considered the standard of care. However, many patients with advanced cancer do not consistently receive specialty palliative care, especially during ...
Jul 28, 2025
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Researcher harnesses AI to transform skin cancer diagnosis in remote areas
A researcher at Heriot-Watt University is harnessing the power of artificial intelligence to give patients living in remote parts access to timely and potentially lifesaving medical diagnoses.
Jul 27, 2025
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Hormone found to suppress immune cells, allowing cancer to evade detection
Researchers at UT Southwestern Medical Center have discovered how a hormone interacts with a receptor on the surface of immune cells to shield cancer cells from the body's natural defenses.
Jul 25, 2025
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Plant virus triggers immune response that targets and destroys cancer cells
A virus that typically infects black-eyed peas is showing great promise as a low-cost, potent cancer immunotherapy—and researchers are uncovering why.
Jul 25, 2025
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