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Cardiology news

Atherosclerosis may meet key criteria for autoimmune disease, evidence suggests

In autoimmune diseases, the immune system turns against the body through pathogenic high-affinity B cells or T cells, leading to severe organ damage. Multiple sclerosis (nervous system paralysis), type 1 diabetes (a strong ...

Mitochondrial DNA mutations may help turn aging hearts toward failure

Researchers at Karolinska Institutet have shown that mutations in mitochondrial DNA (mtDNA), which accumulate in many tissues as we age, can actively contribute to impaired heart function. Until now, it has been difficult ...

What PREVENT can tell you about heart disease risk

We often think about heart disease as something that suddenly happens, like a heart attack, requiring a trip to the emergency room. In reality, cardiovascular disease often develops silently over years or even decades before ...

Brain aneurysm map reveals cell types tied to rupture risk

A new study from UC San Francisco shows how certain cells in the brain may cause aneurysms to weaken and rupture. It helps explain why some aneurysms burst while others do not and could lead to new ways of predicting and ...

Molecular mechanics behind heart cell restructuring revealed

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a common signaling pathway called the ERK pathway acts as a key controller of where the building ...

Statin use linked to lower risk of frailty in older veterans

Researchers at Mass General Brigham have demonstrated that older U.S. veterans who initiated statin therapy were significantly less likely to develop frailty over time, suggesting that the cholesterol-lowering medications ...

Unraveling the mystery of misfolded proteins in the heart

Researchers in the del Monte Lab at the Medical University of South Carolina (MUSC) are the first to observe defects in the protein repair system associated with the peculiar, misfolded protein plaques previously observed ...

Disrupted metabolism linked to heart failure

When heart cells burn fat without normal metabolic controls, they can deplete a lipid needed to keep mitochondria functioning properly, according to a study by UT Southwestern Medical Center researchers. The findings, published ...

Protecting heart health in an era of temperature extremes

Extreme heat and cold are growing cardiovascular risks that can trigger heart attacks, strokes, heart failure, and sudden cardiac death, according to a recent scientific statement by experts at Weill Cornell Medicine and ...

Heart elasticity may hinge on a hidden genetic switch

The human heart must constantly adapt to changing demands—a task that requires tightly coordinated molecular shuffling in heart cells. One of the key regulators of this process is RBM20, a protein that controls an editing ...