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Cardiology news

Biological pacemaker dogma challenged as TBX18 fails and Hcn2 delivers

Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field. In a new preclinical study, they show that the transcription factor TBX18 does not generate true biological pacemaker activity, ...

Researchers develop first synthetic mitral valve model to replicate the heart's natural mechanics

Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics the valve's complex mechanical behavior in the human heart. The study could ...

Brain aneurysm map reveals cell types tied to rupture risk

A new study from UC San Francisco shows how certain cells in the brain may cause aneurysms to weaken and rupture. It helps explain why some aneurysms burst while others do not and could lead to new ways of predicting and ...

Molecular mechanics behind heart cell restructuring revealed

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a common signaling pathway called the ERK pathway acts as a key controller of where the building ...

Statin use linked to lower risk of frailty in older veterans

Researchers at Mass General Brigham have demonstrated that older U.S. veterans who initiated statin therapy were significantly less likely to develop frailty over time, suggesting that the cholesterol-lowering medications ...

Disrupted metabolism linked to heart failure

When heart cells burn fat without normal metabolic controls, they can deplete a lipid needed to keep mitochondria functioning properly, according to a study by UT Southwestern Medical Center researchers. The findings, published ...

Unraveling the mystery of misfolded proteins in the heart

Researchers in the del Monte Lab at the Medical University of South Carolina (MUSC) are the first to observe defects in the protein repair system associated with the peculiar, misfolded protein plaques previously observed ...

Protecting heart health in an era of temperature extremes

Extreme heat and cold are growing cardiovascular risks that can trigger heart attacks, strokes, heart failure, and sudden cardiac death, according to a recent scientific statement by experts at Weill Cornell Medicine and ...

MRI technique enhances valve disease evaluation

A new cardiac magnetic resonance imaging-based measurement may improve how physicians assess a common heart valve condition, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings ...

AI flags heart risks in breast cancer patients

UBC Okanagan researchers, working with scientists at BC Cancer–Kelowna, have developed a groundbreaking AI model that can help identify breast cancer patients who may face a double-threat—that of cancer and cardiovascular ...

Why managing expectations matters in chronic pain treatment

In a 2026 study I conducted with colleagues on people with peripheral arterial disease, one participant described how leg pain had disrupted his golf for years. It forced him to stop mid-round, shake his leg and apologize ...

New cholesterol guidelines aim to stop heart disease earlier

Doctors should consider treating high cholesterol much earlier and more aggressively than they have in the past, according to a new perspective by Weill Cornell Medicine, New York-Presbyterian and Yale School of Medicine ...

Age does not appear to drive cardiovascular risk in pregnancy

Underlying cardiovascular risk, rather than older age, drives complications such as venous thromboembolism, cardiomyopathy and heart failure during pregnancy, according to new Weill Cornell Medicine research. The findings ...

AI coach rewrites the rules of cardiovascular research

Every day, millions of Americans open a fitness app, glance at their step count, and may even feel a mild pang of guilt before closing it again. The problem with most health tracking technology is that it watches your activity, ...