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Cardiology news

'Polypill' for heart failure cuts hospitalizations and ER visits by 60% in trial

A "polypill" combining three medications recommended to treat heart failure into a single daily dose proved far more effective for patients than taking the drugs separately, a randomized clinical trial led by UT Southwestern ...

Congenital heart defects in mothers associated with developmental problems in children

The children of mothers born with heart defects face a higher risk of being developmentally vulnerable, meaning they face challenges related to physical health, emotional maturity and communication, according to a new study ...

Extreme heat is rising—and so is the risk to your heart

As summer heat intensifies across the U.S., the American Heart Association is warning that soaring temperatures don't just make people uncomfortable—they can put serious strain on the heart and increase the risk of life-threatening ...

Elucidating a decades-old mystery of blood clotting

Why is it rare for dangerous blood clots to form in our blood? What happens if this safety mechanism fails? An international team of researchers involving the University of Greifswald has taken a major step toward finding ...

Brain aneurysm map reveals cell types tied to rupture risk

A new study from UC San Francisco shows how certain cells in the brain may cause aneurysms to weaken and rupture. It helps explain why some aneurysms burst while others do not and could lead to new ways of predicting and ...

Molecular mechanics behind heart cell restructuring revealed

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a common signaling pathway called the ERK pathway acts as a key controller of where the building ...

Statin use linked to lower risk of frailty in older veterans

Researchers at Mass General Brigham have demonstrated that older U.S. veterans who initiated statin therapy were significantly less likely to develop frailty over time, suggesting that the cholesterol-lowering medications ...

Unraveling the mystery of misfolded proteins in the heart

Researchers in the del Monte Lab at the Medical University of South Carolina (MUSC) are the first to observe defects in the protein repair system associated with the peculiar, misfolded protein plaques previously observed ...

Disrupted metabolism linked to heart failure

When heart cells burn fat without normal metabolic controls, they can deplete a lipid needed to keep mitochondria functioning properly, according to a study by UT Southwestern Medical Center researchers. The findings, published ...

Protecting heart health in an era of temperature extremes

Extreme heat and cold are growing cardiovascular risks that can trigger heart attacks, strokes, heart failure, and sudden cardiac death, according to a recent scientific statement by experts at Weill Cornell Medicine and ...