Medical research

Crunching the numbers of cancer metastasis

In metastasis, cancer cells break away from the original tumor and take root in another region of the body by entering the blood stream. In order to spread, metastatic cells cross over the endothelium—a barrier of endothelial ...

Oncology & Cancer

Broken heart syndrome linked with cancer

One in six people with broken heart syndrome had cancer and they were less likely to survive for five years after it occurred, according to new international research in Journal of the American Heart Association.

Oncology & Cancer

Daily coffee doesn't affect cancer risk

Drinking coffee does not change a person's risk of being diagnosed with or dying from cancer, a new QIMR Berghofer study has found.

Oncology & Cancer

Unlocking chemo-resistance in cancer

La Trobe University researcher Associate Professor Hamsa Puthalakath is the first scientist to have unlocked a long-standing mystery as to why some cancers do not respond to treatment with one of the most effective chemotherapy ...

Medications

Common steroid could soften up tumors for chemo

A common drug used to alleviate side effects of cancer treatment may also make the treatment more successful if given beforehand, report a consortium of research institutions including the University of Connecticut.

Medical research

Researchers explain muscle loss with menopause

In an article recently published in Cell Reports, lead authors Dawn Lowe, Ph.D., Professor in the Department of Rehabilitation Medicine, Division of Physical Therapy and Rehabilitation Science Graduate Program, University ...

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Breast cancer (malignant breast neoplasm) is a type of cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk. Cancers originating from ducts are known as ductal carcinomas; those originating from lobules are known as lobular carcinomas. Breast cancer is a disease of humans and other mammals; while the overwhelming majority of cases in humans are women, men can sometimes also develop breast cancer.

The size, stage, rate of growth, and other characteristics of the tumor determine the kinds of treatment. Treatment may include surgery, drugs (hormonal therapy and chemotherapy), radiation and/or immunotherapy. Surgical removal of the tumor provides the single largest benefit, with surgery alone being capable of producing a cure in many cases. To somewhat increase the likelihood of long-term disease-free survival, several chemotherapy regimens are commonly given in addition to surgery. Most forms of chemotherapy kill cells that are dividing rapidly anywhere in the body, and as a result cause temporary hair loss and digestive disturbances. Radiation is indicated especially after breast conserving surgery and substantially improves local relapse rates and in many circumstances also overall survival. Some breast cancers are sensitive to hormones such as estrogen and/or progesterone, which makes it possible to treat them by blocking the effects of these hormones.

Worldwide, breast cancer comprises 22.9% of all cancers (excluding non-melanoma skin cancers) in women. In 2008, breast cancer caused 458,503 deaths worldwide (13.7% of cancer deaths in women). Breast cancer is more than 100 times more common in women than breast cancer in men, although males tend to have poorer outcomes due to delays in diagnosis.

Prognosis and survival rate varies greatly depending on cancer type, staging and treatment. However, survival rates across the world are generally good. Overall more than 8 out of 10 women (84%) in England that are diagnosed with the disease survive it for at least 5 years.

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