Oncology & Cancer

An aspirin a day keeps the bowel doctor away

A regular dose of aspirin to reduce the risk of inherited bowel cancer lasts at least 10 years after stopping treatment, research has revealed.

Oncology & Cancer

Mayo Clinic Minute: Symptoms of colorectal cancer

Colorectal cancer refers to a cancer that begins to form in the colon or the rectum. It's the second most common cause of cancer death in the U.S., behind lung cancer.

Medical research

Biosynthetic capacity: The key to switch-off cancer stem cells

Tumours are not a uniform mass of cells. Colon cancers bear differentiated-like cells, similar to the functional cells of the intestinal wall, and pluripotent cells—the so-called tumour stem cells. The latter fuel tumour ...

Oncology & Cancer

Immunotherapy prior to surgery is effective in colon cancer

Patients with colon cancer but without distant metastases can benefit from a short course of immunotherapy while waiting for their surgery, as it can cause tumours to shrink substantially or clear up in a very short time. ...

Oncology & Cancer

Deadlier colon cancer develops differently in women and men

Researchers have found that colon cancer tumor cells produce energy for growth differently in women and men, and that this difference is associated with a more aggressive form of tumor growth with a higher incidence in women.

Oncology & Cancer

5 ways to fight colon cancers

With screening, colon cancers can effectively be detected and prevented. Though colon cancer is the third-leading cause of cancer death in the United States, one-third of Americans over age 50 are not getting screened.

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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.

Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.

Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.

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