As blood cancers are constantly evolving and developing mutations that grow resistance to current treatments, researchers in the University of Cincinnati Cancer Center's Leukemia and Drug Development Lab (LDDL) are constantly ...
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A gene called DNMT3A is important for guiding blood stem cells into forming all the cell types present in blood, including red blood cells, white blood cells and platelets. When this gene accumulates mutations—which might ...
Sep 11, 2025
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Researchers from King's have identified a new way to treat certain blood cancers using existing drugs, by turning a once-dismissed part of our DNA into a therapeutic target.
Sep 11, 2025
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Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might affect cancer growth.
Sep 11, 2025
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Public concern continues to grow about the harmful effects of pesticides and other environmental pollutants, especially for children. Pesticides have previously been linked to a higher risk of developing childhood leukemia. ...
Sep 10, 2025
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In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay. New research shows that using a drug as a blocker to outcompete the SUMO2 ...
Sep 4, 2025
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A Yale study published on the cover of the journal Blood explains basic scientific discoveries that could lead to innovative therapies for acute myeloid leukemia, and specifically a rare and aggressive blood cancer known ...
Sep 1, 2025
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An assay that uses leukemia stem cells (LSCs) to assess measurable residual disease (MRD) outperforms traditional methods in patients with acute myeloid leukemia (AML), according to a study published online Aug. 23 in Bone ...
Aug 29, 2025
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With colorful heart, bow, and flower patterns, the backpacks designed by a Philadelphia cancer philanthropy look from the outside just like the dozens of others filling store shelves as a new school year approaches.
Aug 29, 2025
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Children with acute lymphoblastic leukemia (ALL) from the lowest socioeconomic status (SES) neighborhoods have an increased risk for mortality, according to a study published online Aug. 22 in Blood Advances.
Aug 28, 2025
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Leukemia (American English) or leukaemia (British English) (from the Greek leukos λεύκος - white, and haima αίμα - blood) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, heart, and lymphoid system, which are all known as hematological neoplasms. Leukemia can also cause multiple organ failure.
In 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it.[citation needed]
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