Adding a new drug to standard care for stem cell transplant recipients may reduce a life-threatening side effect, according to an early-stage clinical trial conducted at Washington University School of Medicine in St. Louis.
Dec 5, 2024
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A new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The method also works for other forms of cancer where resistance may develop. A step is ...
Dec 4, 2024
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Researchers at the Icahn School of Medicine at Mount Sinai have discovered how genetics can affect the success of venetoclax, a treatment for multiple myeloma, a rare type of blood cancer. Their study, "Predictors of Response ...
Nov 29, 2024
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Patients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) who were treated with the novel anti-CD19 chimeric antigen receptor (CAR) T cell therapy, obecabtagene autoleucel (obe-cel), experienced ...
Nov 28, 2024
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A new thesis from Karolinska Institutet shows the effectiveness of flexible parametric survival models in modeling multiple time-scales, providing a robust tool for complex time-to-event data analysis. The models were tested ...
Nov 25, 2024
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Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients with acute lymphoblastic leukemia who have a higher risk version of the disease and are ...
Nov 25, 2024
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Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), ...
Nov 25, 2024
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The risk for COVID-19 hospitalization is low in adults with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), but these individuals have a high mortality risk, according to a study published online Oct. 16 ...
Nov 21, 2024
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The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of "living drugs"—T-cells modified to expand, recognize and attack cancer cells within the body—offer ...
Oct 29, 2024
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What keeps some immune systems youthful and effective in warding off age-related diseases? In a new paper published in Cellular & Molecular Immunology, USC Stem Cell scientist Rong Lu and her collaborators point the finger ...
Oct 23, 2024
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