Oncology & Cancer

Statistical models predict benefit of non-intensive AML therapy

An international team has developed statistical models to predict the risk of early death in patients being treated with non-intensive therapies for acute myeloid leukemia (AML). Results of analyses using the models will ...

Oncology & Cancer

How alike are the cancer cells from a single patient?

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy. To carry out these behaviors, each ...

Oncology & Cancer

Finding new targets for acute myeloid leukemia in children

Acute myeloid leukemia (AML) is the second most common leukemia diagnosed in children. It is hard to treat and can be fatal in some cases. While there have been some recent successes with genetically targeted therapies for ...

Oncology & Cancer

Decreasing DNA repair and genomic instability

The journal Oncotarget has published "Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal ...

Oncology & Cancer

Exploiting cancer's sweet tooth to develop a treatment

Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it. Cold Spring ...

Medications

Personalized treatments for blood and bone cancer

Personalization, something made especially for you, can make everything better, from the clothes you wear to the car you drive. Now, the type of medical treatment you receive can also be personalized.

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