Many patients with chronic illnesses such as AIDS, cancer and autoimmune diseases suffer from an additional disease called cachexia. The complex, still poorly understood syndrome, with uncontrollable weight loss and shrinkage ...
May 21, 2019
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Ghana on Tuesday rolled out the world's only proven malaria vaccine for infants as part of a landmark campaign against the deadly mosquito-borne disease, one week after Malawi became the first country to do so.
Apr 30, 2019
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The quantity and quality of antibodies that recognize the end region of the malaria parasite's CSP protein is a good marker of protection by the RTS,S/AS01E vaccine, according to a study led by the Barcelona Institute for ...
May 15, 2019
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A first-of-its-kind study reveals malaria spending in 2016 totaled $4.3 billion globally, far short of the annual funding target of $6.6 billion set by the World Health Organization.
Apr 26, 2019
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Dear Mayo Clinic: I'm planning a three-week trip to Tanzania. My doctor recommends that I take medication to prevent malaria. Is this really necessary? I thought malaria wasn't common anymore. Are there other things that ...
May 13, 2019
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In people with chronic malaria, certain metabolic systems in the blood change to support a long-term host-parasite relationship, a finding that is key to eventually developing better detection, treatment and eradication of ...
May 02, 2019
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Malaria is a leading cause of death and illness around the world. Over 200 million cases are reported every year, and more than 400 000 people die. More than 90% of cases are reported in sub-Saharan Africa. Scientists have ...
Apr 30, 2019
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The powerful medicines known as artemisinins have plenty of mileage in them in the global fight against malaria, and concern about partial resistance has been overstated.
Apr 26, 2019
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U.S. government aid for treating children and adults with HIV and malaria in developing countries has done more than expand access to lifesaving interventions: It has changed how people around the world view the United States, ...
May 16, 2019
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The Global Health Impact Index, developed by faculty at Binghamton University, State University of New York to rank pharmaceutical companies based on their drugs' impact on global health, is launching a new, more-robust model ...
May 06, 2019
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The oceans cover more than 70 percent of the earth's surface and provide a rich source of unique, bioactive natural products. Their chemical diversity and structural complexity represent an untapped supply of potential new ...
May 16, 2019
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Climate variability, which might arise through global warming or other factors has been shown to have an impact on mortality rates in sub-Saharan Africa, according to research published in the International Journal of Environment ...
May 15, 2019
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Imperial medical students have helped to devise a new type of 'decoy' drug to tackle infections that are resistant to antibiotics.
May 15, 2019
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If ever there were proof that humans are animals too, it's in the diseases that we share with other species. From rabies and Zika to Ebola and bird flu, many deadly diseases around the world can pass between animals and people.
May 07, 2019
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Girls began queuing at their local school with their friends, waiting for their names to be called. Many were apprehensive. After all, most of them had not had a vaccination since they were babies. It was 2013 and a new vaccine ...
May 07, 2019
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Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases progressing to coma or death. It is widespread in tropical and subtropical regions, including much of Sub-Saharan Africa, Asia, and the Americas.
Five species of Plasmodium can infect and be transmitted by humans. Severe disease is largely caused by Plasmodium falciparum while the disease caused by Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae is generally a milder disease that is rarely fatal. Plasmodium knowlesi is a zoonosis that causes malaria in macaques but can also infect humans.
Malaria transmission can be reduced by preventing mosquito bites by distribution of mosquito nets and insect repellents, or by mosquito-control measures such as spraying insecticides and draining standing water (where mosquitoes breed). Despite a clear need, no vaccine offering a high level of protection currently exists. Efforts to develop one are ongoing. A number of medications are also available to prevent malaria in travelers to malaria-endemic countries (prophylaxis).
A variety of antimalarial medications are available. Severe malaria is treated with intravenous or intramuscular quinine or, since the mid-2000s, the artemisinin derivative artesunate, which is superior to quinine in both children and adults. Resistance has developed to several antimalarial drugs, most notably chloroquine.
There were an estimated 225 million cases of malaria worldwide in 2009. An estimated 655,000 people died from malaria in 2010, a 5% decrease from the 781,000 who died in 2009 according to the World Health Organization's 2011 World Malaria Report, accounting for 2.23% of deaths worldwide. Ninety percent of malaria-related deaths occur in sub-Saharan Africa, with ~60% of deaths being young children under the age of five. Plasmodium falciparum, the most severe form of malaria, is responsible for the vast majority of deaths associated with the disease. Malaria is commonly associated with poverty, and can indeed be a cause of poverty and a major hindrance to economic development.
This text uses material from Wikipedia licensed under CC BY-SA
