People who have experienced more than one tattoo session may have a decreased risk of the skin cancer melanoma—with one key caveat, according to research from Huntsman Cancer Institute at the University of Utah (the U).
20 hours ago
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A multi-institutional clinical trial conducted at the UNC Lineberger Comprehensive Cancer Center and 21 other U.S. sites found that a single administration of autologous tumor-infiltrating lymphocyte (TIL) cell therapy helped ...
Aug 28, 2025
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A new study from Moffitt Cancer Center may offer a breakthrough for patients with advanced melanoma who don't respond to current immunotherapy treatments. The research, published in the Journal for ImmunoTherapy of Cancer, ...
Aug 18, 2025
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A research team co-led by UCLA investigators has found that pembrolizumab, an immunotherapy drug that helps the immune system attack cancer cells, can effectively shrink or eliminate tumors in patients with unresectable advanced ...
Aug 14, 2025
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Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body. The malignant cells become dependent on this protein to migrate, pointing to new strategies for ...
Aug 1, 2025
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A team headed by Claude Perreault, Director of IRIC's Immunobiology Research Unit and Professor at the Faculty of Medicine at Université de Montréal, has identified novel tumor antigens that could lead to the development ...
Jul 29, 2025
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Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to COVID-19 home tests, according to University of Michigan researchers.
Jul 24, 2025
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New research has found a novel target with therapeutic potential for metastatic eye melanoma—an aggressive eye cancer—with implications for a range of other cancers.
Jul 7, 2025
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Pathologists' examinations of tissue samples from skin cancer tumors improved when they were assisted by an AI tool. The assessments became more consistent and patients' prognoses were described more accurately. This is shown ...
Jul 3, 2025
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Institut Curie researchers have identified a sex-specific molecular pathway connecting E-cadherin loss, estrogen receptor-α (ERα), and GRPR, contributing significantly to increased melanoma metastasis in women.
Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
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