Overweight & Obesity

Probiotic supplements may enhance weight loss in obese children

Probiotic supplements may enhance weight loss and improve the metabolic health of obese children folowing a diet and exercise plan, according to research presented today at the 58th Annual European Society for Paediatric ...

Medical research

Exploring better fatty liver remedies

Obesity often leads to increased accumulation of fat in the liver, which can, over time, result in diabetes, poor liver function, and liver cancer. It's increasingly a problem affecting obese children and young people who ...

Neuroscience

Potential target for diabetes-associated Alzheimer's disease

Researchers have identified a protein that may contribute to the progression of Alzheimer's disease pathology in type-2 diabetes, reports a new study of male mice and human brain tissue. The research, published in JNeurosci, ...

Medications

Linagliptin noninferior for CV risk in early type 2 diabetes

(HealthDay)—Linagliptin is noninferior to glimepiride for adults with relatively early type 2 diabetes and elevated cardiovascular risk, according to a study published online Sept. 19 in the Journal of the American Medical ...

page 1 from 23

Diabetes mellitus type 2 – formerly non-insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes – is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. The classic symptoms are excess thirst, frequently having to urinate, and constant hunger. Type 2 diabetes makes up about 90% of cases of diabetes with the other 10% due primarily to diabetes mellitus type 1 and gestational diabetes. Obesity is the primary cause of type 2 diabetes in people who are genetically predisposed to the disease.

Type 2 diabetes is initially managed by increasing exercise and dietary modification. If blood sugars are not lowered by these measures, medications such as metformin or insulin may be needed. In those on insulin there is typically the requirement to routinely check blood sugar levels.

Rates of diabetes have increased markedly over the last 50 years in parallel with obesity. As of 2010 there are approximately 285 million people with the disease compared to around 30 million in 1985. Long-term complications from high blood sugar can include heart attacks, strokes, diabetic retinopathy where eye sight is affected, kidney failure which may require dialysis, and poor circulation of limbs leading to amputations. The acute complication ketoacidosis is uncommon unlike in type 1 diabetes, nonketonic hyperglycemia however may occur.

This text uses material from Wikipedia licensed under CC BY-SA