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Gastroenterology news
Colorectal screening boosts early diagnoses in first two years, randomized trial suggests
More cases of colorectal cancer are detected at an early stage with screening. This is according to new research based on data from over 278,000 60-year-olds, who were randomly selected to undergo one of two interventions ...
1 hour ago
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Will probiotics work for you? Models map gut metabolism to predict success
A new study demonstrates that computer models of gut metabolism can predict which probiotics will successfully establish themselves in a person's gut and how different prebiotics affect production of health-promoting short-chain ...
14 hours ago
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Oral vaccine strategy used modified bacterium to combat colorectal cancer
A research team investigating the use of the bacterium Listeria monocytogenes against colorectal cancer has discovered a way to build a modified version of Listeria as an oral vaccine to prime the immune system directly within ...
14 hours ago
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What's 'scromiting'? Here's what to know about the cannabis-related condition
Some people have described a bizarre side effect after using marijuana: uncontrollable vomiting. It's sometimes called "scromiting"—a mash-up of screaming (from intense pain) and vomiting. The medical term is cannabis hyperemesis ...
11 hours ago
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New FAP-Index could transform early detection of severe liver disease
Researchers from the Centenary Institute have developed a new diagnostic tool, the FAP-Index, that could significantly improve how doctors identify people at risk of serious liver damage caused by metabolic fatty liver disease. ...
20 hours ago
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Scientists discover 'bacterial constipation,' a new disease caused by gut-drying bacteria
Scientists at Nagoya University in Japan have found two gut bacteria working together that contribute to chronic constipation. The duo, Akkermansia muciniphila and Bacteroides thetaiotaomicron, destroy the intestinal mucus ...
Feb 19, 2026
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Experimental vaccine protects against C. diff disease and recurrence
A novel vaccination approach developed by Vanderbilt Health researchers cleared the harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. An experimental vaccine administered to the mucosal ...
Feb 18, 2026
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Missing ANGPTL4 gene in mice reprograms immunity, shielding against gut inflammation
A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation. ...
Feb 18, 2026
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Vascularized liver tissueoid-on-a-chip models regeneration and transplant rejection
Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling ...
Feb 18, 2026
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Machine-learned biomarker identifies those at high risk for liver cancer
Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed a score that predicts the risk of liver cancer. Published in the journal Proceedings of the National Academy ...
Feb 18, 2026
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What is gut health? Experts agree on a clear meaning for the term
Walk down the aisles of many grocery stores and you're liable to see claims about products that are "good for gut health," from yogurt and kombucha to supplements and even sodas. But despite its popularity, the phrase can ...
Feb 18, 2026
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Disease patterns found to vary with genetic ancestry for Hispanic patients with IBD
Hispanic patients with inflammatory bowel disease (IBD) have varying disease patterns depending on their genetic ancestry, according to a study published online Feb. 9 in Gastroenterology.
Feb 18, 2026
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Bowel cancer rates are rising among young people—but they can reduce their risk
Bowel cancer has been making headlines around the world, following the death last week of actor James Van Der Beek. The former Dawson's Creek actor was diagnosed with colorectal cancer at age 45.
Feb 18, 2026
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FDA approves noninvasive Optune Pax device for advanced pancreatic cancer
The U.S. Food and Drug Administration has approved a first-of-its-kind, noninvasive device, the Optune Pax, for the treatment of adult patients with locally advanced pancreatic cancer. Approval of Optune Pax was granted to ...
Feb 18, 2026
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FDA-approved drug may reverse T-cell exclusion in fibrolamellar liver cancer
Immunotherapy—which activates the body's own immune system to kill cancer cells—has not worked well against a rare and fatal liver cancer, but a new study finds an existing FDA-approved drug may allow the immunotherapy ...
Feb 17, 2026
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C-reactive protein links to ventricular repolarization in coronary artery disease, study finds
A new study reveals that the predictive power of key inflammatory markers, such as C-reactive protein, shifts fundamentally depending on whether a patient suffers from cirrhosis or acute/chronic coronary disease.
Feb 17, 2026
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Why are more under-50s getting colorectal cancer? 'We don't know'
The death of US actor James Van Der Beek was just the latest reminder that colorectal cancer has been surging among people under 50 in recent years—and no one knows why.
Feb 17, 2026
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Studies show 11 genetic variants affect gut microbiome
In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions of the human genome have a clear influence on which bacteria are in the gut and what they do there. Only two genetic ...
Feb 16, 2026
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NSMF protein identified as key regulator in colorectal cancer
A research team affiliated with UNIST has unveiled a novel approach to halt the progression of colorectal cancer by inducing irreversible cellular aging. Their findings demonstrate that suppressing a neural protein called ...
Feb 16, 2026
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Researchers identify key mechanism driving progression of fatty liver disease to cancer
According to recent reports from the Korean government, the incidence of alcoholic liver disease—previously the leading indication for liver transplantation—has been decreasing. This trend initially raised expectations ...
Feb 16, 2026
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IBD study tracks 54,000 patients, links dysplasia grade to cancer risk
Precancerous colorectal lesions, or dysplasia, in patients with inflammatory bowel disease (IBD) confer markedly different risks of future colorectal cancer depending on dysplasia grade, according to a comprehensive registry ...
Feb 16, 2026
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How pancreatic cancer prepares the tumor environment: A possible biomarker for the earliest stage of development
Even before a tumor in the pancreas becomes discernible, an activated cancer gene actively remodels its future environment and creates an inflammatory and immune-defensive microenvironment in which the carcinoma can grow. ...
Feb 13, 2026
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Colorectal cancer is increasing among young people, James Van Der Beek's death reminds
An increasing number of people are dying of colorectal cancer at a young age, including those as young as 20. Actor James Van Der Beek, who was diagnosed with colorectal cancer in 2023, died at age 48 on Feb. 11, 2026, bringing ...
Feb 13, 2026
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Cholesterol crystals may trigger some liver disease
Cholesterol crystals in the liver may stiffen the organ early in those with metabolic dysfunction-associated steatotic liver disease (MASLD)—well before scarring develops—according to new research from a team in the Perelman ...
Feb 12, 2026
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