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Gastroenterology news
Digital decision support tool proven to reduce risks in bowel surgery
Recent research provides robust evidence for the use of a digital visualization and decision support tool in colorectal (bowel) surgery. This is the first time that a digital decision support tool has been conclusively proven ...
7 hours ago
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Promising active substance against hepatitis E identified
Around 70,000 people die each year from infections with the hepatitis E virus. There is currently neither a vaccine nor a specific drug against this virus. This could change with the identification of bemnifosbuvir as a compound ...
16 hours ago
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Gut microbiome thrives on fiber—tapeworms confirm it
Intestinal worms can help reduce inflammation in the human body—but only if they have enough dietary fiber. Without it, they switch into a hibernation-like state and their protective effect disappears. This is the finding ...
Mar 19, 2026
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Switching from milk to solid food in early life helps reprogram the gut's immune defenses, researchers find
According to a team of researchers at Baylor College of Medicine, Tongji University and collaborating institutions, weaning or switching from milk to solid food in early life doesn't just change what babies eat, it helps ...
Mar 19, 2026
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Student shines a light on rare colon cancer
Colon cancer is one of the most common cancers in the U.S., with more than 100,000 cases diagnosed each year. But some people develop a highly aggressive form of colon cancer that is extremely rare, making up 0.02% to 0.1% ...
Mar 19, 2026
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Cholecystokinin, not insulin, may be key hormone in obesity-driven pancreatic cancer
Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels. Scientists have thought that this excessive insulin secretion ...
Mar 18, 2026
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Hope for preventing stomach cancer: Drug candidate proves extremely effective against H. pylori
Researchers at the Technical University of Munich (TUM) have increased the effectiveness of a standard antibiotic by a factor of 60 through targeted chemical modifications. In laboratory and animal studies, the new drug candidate ...
Mar 18, 2026
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New study identifies how obesity-related liver cancer becomes more aggressive and resistant to treatment
A research team affiliated with UNIST has made a significant discovery explaining why liver cancers associated with obesity and metabolic disorders tend to be more aggressive and less responsive to conventional treatments. ...
Mar 18, 2026
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Medications for alcohol use disorder reduce hospitalizations and health care costs
Alcohol use disorder (AUD) remains a major public health challenge in the United States, contributing to more than 170,000 deaths each year and imposing an estimated $249 billion economic burden through health care costs, ...
Mar 18, 2026
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'Junk DNA' may help defend against colorectal cancer
For decades, large portions of the human genome were labeled "junk DNA." New research from Western University and London Health Sciences Centre Research Institute (LHSCRI) suggests these overlooked sequences may help protect ...
Mar 17, 2026
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Heart disease risk tied to certain molecules made by gut microbes
In a study involving data from thousands of people, the risk of a new coronary heart disease diagnosis was statistically associated with bloodstream levels of nine specific molecules that are produced by gut microbes. Danxia ...
Mar 17, 2026
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Detection of bowel cancer marker in wastewater may offer new early warning system
Detection of a bowel cancer marker (CDH1) in wastewater may offer a new community-level early warning system for the disease, suggests a proof-of-concept study published in the Journal of Epidemiology and Community Health. ...
Mar 17, 2026
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Recommendations presented for management of hepatic encephalopathy
In a clinical guideline issued by the American College of Gastroenterology and published in the March issue of the American Journal of Gastroenterology, recommendations are presented for the diagnosis and management of hepatic ...
Mar 17, 2026
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Recommendations developed for faltering weight in children
In a clinical practice guideline issued by the American Academy of Pediatrics, in partnership with the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, recommendations are presented for the ...
Mar 17, 2026
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The Alzheimer's gut-brain link: How butyrate could curb amyloid-β buildup and inflammation
Alzheimer's disease (AD) is a neurodegenerative disease that causes progressive memory loss and a significant decline in mental functions. Past studies have shown that people with AD exhibit a buildup of a protein called ...
Early life stress linked to long-lasting digestive issues
Early life stress may lead to digestive issues later in life, driven by changes in the gut and sympathetic nervous systems, according to a new study published in the journal Gastroenterology.
Mar 16, 2026
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The hidden signals of Crohn's disease: Why remission is not recovery
Imagine a patient with Crohn's disease—after months of flares, they are finally in clinical remission. Their biomarkers are stable, their pain has subsided, and their doctors are satisfied. They are on the gold standard ...
Study maps cellular mechanisms driving fibrosis in Crohn's disease
Researchers at the Earlham Institute, the University of Edinburgh and Heriot-Watt University analyzed gut cells to understand the drivers behind fibrosis, a common complication in Crohn's disease affecting 10–20% of patients. ...
Mar 16, 2026
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The gut can drive age-associated memory loss, research reveals
We become forgetful as we age. This is often seen as a universal truth, but in fact it is far from universal: some people remain incredibly sharp at 100 years old, while others experience memory loss starting in middle age.
Mar 15, 2026
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'Bugs delivering drugs': A new approach to colorectal cancer treatment using common food-borne bacteria
Baylor University researchers have developed a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells. Michael S. VanNieuwenhze, Ph.D., FRSC, ...
Mar 15, 2026
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Study maps three biological routes for gastric cancer beyond H. pylori
A study in Gut shows that gastric cancer is shaped by complex interactions between environmental exposure, microbes, host, and tumor biology. The findings reveal distinct cancer routes and targets linked to prognosis and ...
Mar 15, 2026
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Berberine as a natural Ozempic? An analysis of a popular myth
In recent years, berberine has increasingly appeared in the public sphere as a "natural way" to improve metabolism. In social media, it is sometimes compared to incretin drugs and even referred to as "plant-based Ozempic." ...
Mar 13, 2026
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Study finds CDK4/6 plus EGFR blockade kills pancreatic cancer cells without KRAS drugs
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 inhibition offers an indirect ...
Mar 13, 2026
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Uncovering a key signaling pathway linking liver cancer and fibrosis
New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better treatment strategies, report researchers from Institute of Science Tokyo. Through a comprehensive analysis ...
Mar 13, 2026
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New strategy intercepts pancreatic cancer by eliminating microscopic lesions before they become cancer
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors. Using an experimental therapy to target microscopic precancerous lesions in the ...
Mar 12, 2026
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