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Gastroenterology news
Engineered probiotic senses inflammation and helps repair the gut in mice
Inflammatory bowel disease damages the lining that separates the gut's contents from the rest of the body. Calming the inflammation is only part of the treatment challenge, however—that protective barrier also needs to heal.
3 hours ago
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Hereditary lung and liver disease successfully treated for the first time using gene correction
Alpha-1 antitrypsin deficiency (AATM) is a congenital metabolic disorder. It is caused by a genetic defect, which results in the protective protein alpha-1 antitrypsin (AAT) being produced incorrectly. This deficiency primarily ...
20 hours ago
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Gut immune cells sustain pain even without inflammation through newly identified signaling pathway
People with inflammatory bowel conditions such as ulcerative colitis often suffer from severe, long-lasting gut pain that lingers even after signs of inflammation are gone. Such abdominal pain can significantly affect one's ...
Single blood protein stands out among 30 tests for assessing fatty liver disease
The reliable assessment of metabolic dysfunction-associated steatotic liver disease (MASLD) is crucial for determining the stage of the disease, initiating appropriate treatments and monitoring the course of therapy. To date, ...
Nov 1, 2026
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Vegans may have less diverse gut bacteria, with lower protein intake offering possible clue
The gut is home to billions of microorganisms. It is a complex ecosystem that regulates many of the body's functions and helps keep us healthy—when it is in balance. Our diet influences this ecosystem. But does it matter ...
Oct 30, 2026
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7 predictors of renal dysfunction identified in patients with IBD
For patients with inflammatory bowel disease (IBD), predictors of renal dysfunction have been identified and include osteoporosis, enteral nutrition, and intestinal surgery, according to a study published in BMC Gastroenterology.
Oct 30, 2026
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Surgical recurrence less frequent with laparoscopic surgery for Crohn disease
For patients undergoing elective intestinal resection for Crohn disease (CD), cumulative surgical recurrence rates are lower with laparoscopic versus open surgery, according to a study published online July 23 in Techniques ...
Oct 30, 2026
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Colorectal cancer in younger patients shows distinct cellular and gene-activity patterns
Mass General Brigham researchers from the Gene Lay Institute of Immunology and Inflammation, along with researchers at Dana-Farber Cancer Institute and the Broad Institute, have uncovered biological clues to why colorectal ...
Oct 29, 2026
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Noninvasive tests detect advanced liver scarring and could reduce reliance on biopsies
Two major international studies have delivered the strongest evidence to date on which noninvasive tests can accurately diagnose and measure the severity of metabolic dysfunction-associated steatotic liver disease (MASLD) ...
Oct 29, 2026
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Common gut virus infects bacteria—not human cells
Thriving alongside trillions of bacteria in the human digestive tract is a vast population of viruses. Ever since one such denizen of the gut microbiome, known as picobirnavirus, was first spotted decades ago, researchers ...
Oct 29, 2026
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The parts of fruits and vegetables most throw away could save your health—and the planet
Most of us routinely discard the peels, skins, stalks and seeds of fruits and vegetables at mealtime. But new research from King's College London suggests these scraps could be a valuable—and overlooked—source of dietary ...
Oct 29, 2026
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Snake-inspired soft robot could help doctors diagnose and treat small intestine disorders
Disorders of the small intestine are often difficult to diagnose and treat. More than 20 feet (6.1 meters) long, an inch (2.5 centimeters) in diameter and located deep within the body, this organ is harder to access than ...
Oct 28, 2026
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Improve IBD bowel checks for early cancer detection
The first U.K.-wide analysis of bowel screening for patients with inflammatory bowel disease (IBD) has identified opportunities to improve the early detection of cancer. The study—the largest of its kind globally—found that ...
Oct 28, 2026
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How the tumor environment influences bowel cancer cells' behavior and chemotherapy response
New research led by experts at the University of Nottingham has revealed how collagen in the tumor environment can alter bowel cancer cell behavior and influence inflammatory responses to chemotherapy, highlighting potential ...
Oct 28, 2026
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Rising rates of colorectal cancer found in nearly all age groups
Colorectal cancer rates are rising across younger and older age groups, according to a study published in NEJM Evidence.
Oct 27, 2026
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The degree of obesity may influence the outcomes of acute pancreatitis
In acute pancreatitis, mild obesity might more than double the odds of vital organ failure, according to an international study by researchers at Semmelweis University analyzing data from more than 2,200 patients. The study, ...
Oct 27, 2026
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Treatment revives old liver cells in lab study, may help prevent Alzheimer's and heart disease
The liver's job of clearing harmful substances from the body is so essential that the organ may have implications for addressing unexpected diseases, including Alzheimer's and heart disease. A promising example comes from ...
Oct 26, 2026
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Fructose slows liver tumors in mice when key sugar-processing gene is missing, may lead to new treatments
Fructose is an important nutrient that, despite having a chemical structure very similar to that of glucose, is metabolized very differently in the body. Research into fructose metabolism and its regulation of metabolism ...
Oct 26, 2026
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Omega-3 EPA linked to longer survival after surgery for colorectal cancer liver metastases
Patients assigned to receive high-dose eicosapentaenoic acid (EPA), an omega-3 fatty acid, before and after surgery for colorectal cancer liver metastases had longer overall survival than those assigned to receive placebo, ...
Oct 26, 2026
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Gut microbiome may help explain why sleep improvement varies after hydrogen supplementation
A Hiroshima University–led clinical trial found that hydrogen supplementation did not significantly improve sleep quality compared with a placebo; however, exploratory analyses suggest that differences in the abundance of ...
Oct 23, 2026
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Study identifies potential new treatment targets for the most common type of bowel cancer
Research published today identifies potential new ways to treat the most common type of colorectal cancer in Ireland. The study, conducted by an international research team led by RCSI University of Medicine and Health Sciences ...
Oct 23, 2026
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Once-daily oral icotrokinra outperforms placebo in ulcerative colitis
For patients with moderately to severely active ulcerative colitis, oral icotrokinra, a peptide that blocks the interleukin-23 receptor, yields a clinical response at week 12 significantly more often than placebo, according ...
Oct 23, 2026
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FDA approves hepatitis B shot that may let some patients stop all treatment
Some adults with chronic hepatitis B may now have a path to something today's treatments rarely deliver—stopping all medication while the virus stays in check.
Oct 23, 2026
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Common multiple sclerosis treatment linked to bowel disease risk
People with multiple sclerosis (MS) who are treated with rituximab have an increased risk of developing inflammatory bowel disease, particularly Crohn's disease, although the absolute risk remains low. This is according to ...
Oct 22, 2026
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Liver tumors form without detectable driver mutations in mice, revealing epigenetic route
Cancers can develop through epigenetic pathways even without driver gene mutations (DGMs), according to a study from Science Tokyo. Researchers uncovered the YAP1–TEAD–TET1 axis, which triggers DNA demethylation and activates ...
Oct 22, 2026
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