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Gastroenterology news
Skipping sweets during antibiotic treatment may help protect the gut microbiome
A new study by researchers at City of Hope suggests eating less sugar could protect the microbiome during antibiotic treatment. The study followed patients with blood cancer undergoing an intensive treatment called allogeneic ...
20 hours ago
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Serum 25(OH)D may serve as a biomarker of disease activity in IBD
For patients with inflammatory bowel disease (IBD), serum 25-hydroxyvitamin D (25[OH]D) may serve as a biomarker for disease activity, according to a study published online Sept. 10 in the Journal of Clinical Medicine.
13 hours ago
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Promising therapy for fatty liver disease reduces fat, inflammation, and scarring in preclinical models
For millions of people living with metabolic dysfunction-associated steatohepatitis (MASH), treatment options remain limited. The progressive form of fatty liver disease develops when excess fat accumulates in the liver, ...
Sep 29, 2026
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Distinct gut microbiome patterns found in five cancer groups and in early-onset cancers
Mayo Clinic researchers have discovered distinct gut microbiome patterns in adults 50 or younger with colorectal and breast cancers compared with those diagnosed later in life—one of several findings from an analysis of stool ...
Sep 29, 2026
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Microplastics clog liver immune cells, driving fat buildup in mice
Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it. These ...
Sep 29, 2026
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Aspirin did not prevent recurrence after liver metastasis surgery, study shows
Colon and rectal cancer often spread to the liver. In some patients, the metastases can be surgically removed or destroyed using local treatment with the aim of curing the disease. Despite this, the cancer often returns. ...
Sep 29, 2026
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Stomach bacterium hijacks healing signals to drive precancerous changes, study finds
Stomach cancer is one of the deadliest forms of cancer. Unlike many other types of cancer, however, one of its main causes is well known: chronic infection with the bacterium Helicobacter pylori. A team headed by Charité—Universitätsmedizin ...
Sep 28, 2026
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Experimental mRNA therapy dramatically extends treatment window for acetaminophen overdose in preclinical models
When a patient arrives at the hospital with an acetaminophen overdose, it's often a race against the clock. The only FDA-approved antidote for overdose-related liver injury, N‑acetylcysteine, must be administered within hours ...
Sep 28, 2026
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High-salt diet may drive fatty liver disease differently in lean people
Fatty liver disease is commonly associated with obesity, yet a growing number of people with normal body weight develop a severe form of the condition. Scientists at Duke-NUS Medical School have identified a distinct mechanism ...
Sep 28, 2026
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Gut microbiome can reveal risk of type 2 diabetes
Changes in the composition of gut bacteria could provide an early warning of type 2 diabetes (T2D), according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) ...
Sep 27, 2026
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Experimental gene-silencing therapy offers hope for hepatitis B cure
Chronic hepatitis B is a long-lasting condition caused by the hepatitis B virus (HBV) that affects about 240 million people worldwide. Most people infected show no symptoms for years, but when symptoms do appear, they can ...
How the treatment of interleukin-6-driven diseases can be refined
Interleukin-6 (IL-6) is a contradictory molecule in immunology. It helps the liver regenerate after injury and protects against infections, yet it also drives chronic inflammation in rheumatic diseases, inflammatory bowel ...
Sep 25, 2026
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Why some patients may develop severe intestinal inflammation after CAR-T therapy
Researchers at the Icahn School of Medicine at Mount Sinai have identified biological mechanisms that may contribute to CAR-T cell-associated enterocolitis, a serious inflammatory condition of the intestine that can occur ...
Sep 25, 2026
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Steatotic liver disease risk scores compared for predicting cirrhosis
For patients with steatotic liver disease (SLD), the steatosis-associated fibrosis estimator (SAFE) score demonstrated the greatest net benefit for predicting cirrhosis, according to a study published online Sept. 21 in JAMA ...
Sep 25, 2026
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Appendectomy for appendicitis associated with 58% lower colorectal cancer risk than antibiotics alone
Patients who underwent an appendectomy for acute appendicitis had a significantly lower subsequent risk of colorectal cancer than similar patients treated with antibiotics alone, according to new research.
Sep 25, 2026
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Metastatic colorectal cancer is more advanced in younger patients than in older ones, but they survive longer
Metastatic colorectal cancer (mCRC) continues to increase among patients 45 and younger. Their longer survival and different disease patterns compared with older patients may warrant closer scrutiny of gastrointestinal symptoms, ...
Sep 25, 2026
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High-fat diet activates cellular repair pathway that helps colon cancer spread
Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.
Sep 24, 2026
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Food molecules transformed by gut bacteria and liver can still influence gene activity
The human liver and gut bacteria can alter molecules in food to influence signaling pathways that can activate or deactivate an array of genes, according to a new study led by researchers at Penn State.
Sep 24, 2026
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Restoring enzyme involved in cellular cleanup could reduce inflammation and scarring from liver disease MASH
A team of investigators co-led by Cedars-Sinai Health Sciences University has identified an enzyme that helps prevent the most common form of liver disease from progressing toward liver failure. Results of the preclinical ...
Sep 24, 2026
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New polymer could enable gastrointestinal transit monitoring without ionizing radiation
Scientists have developed a new fluorine-based tracer that can be tracked using magnetic resonance imaging (MRI) to monitor how quickly food moves through the gastrointestinal tract. The new method has so far been successfully ...
Sep 24, 2026
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Climate change is expanding extreme heat's threat to human health
I was 12 when the worst heat waves hit our home in rural New South Wales, Australia. It was summer vacation, a few weeks after we'd celebrated Christmas. I sat at the kitchen table, next to the sheets draped as curtains over ...
Sep 24, 2026
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AI tool finds biological signals in the gut microbiome that other methods miss, may flag early signs of disease
University of Missouri researchers are using artificial intelligence to uncover hidden clues among the trillions of bacteria living in the human gut, including changes that could one day help scientists detect diseases earlier. ...
Sep 24, 2026
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IBD not linked to risk of hypertensive disorders of pregnancy overall
Inflammatory bowel disease (IBD) is not associated with an increased risk of hypertensive disorders of pregnancy overall, but it is associated with an increased risk of preeclampsia, according to a study published in the ...
Sep 24, 2026
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Probiotics linked to fewer deaths in premature babies
Probiotic supplementation in very preterm babies was linked to a lower risk of both severe intestinal disease and death. This is shown by a new study from the Karolinska Institutet, published in JAMA Network Open. The findings ...
Sep 23, 2026
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Fiber is both diet fad and fixture for good health—why there is no one‑size‑fits‑all way to increase intake
The numbers are clear: Americans aren't getting enough fiber.
Sep 23, 2026
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