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Gastroenterology news

Engineered probiotic senses inflammation and helps repair the gut in mice

Inflammatory bowel disease damages the lining that separates the gut's contents from the rest of the body. Calming the inflammation is only part of the treatment challenge, however—that protective barrier also needs to heal.

Hereditary lung and liver disease successfully treated for the first time using gene correction

Alpha-1 antitrypsin deficiency (AATM) is a congenital metabolic disorder. It is caused by a genetic defect, which results in the protective protein alpha-1 antitrypsin (AAT) being produced incorrectly. This deficiency primarily ...

Common gut virus infects bacteria—not human cells

Thriving alongside trillions of bacteria in the human digestive tract is a vast population of viruses. Ever since one such denizen of the gut microbiome, known as picobirnavirus, was first spotted decades ago, researchers ...

Improve IBD bowel checks for early cancer detection

The first U.K.-wide analysis of bowel screening for patients with inflammatory bowel disease (IBD) has identified opportunities to improve the early detection of cancer. The study—the largest of its kind globally—found that ...