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Gastroenterology news
Developing clinical-grade intestinal organoids for regenerative medicine applications
Inflammatory bowel disease (IBD) and other intestinal disorders affect millions of people worldwide, often causing lasting damage to the lining of the gut. In severe cases, this damage can become irreversible, leaving surgery ...
34 minutes ago
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Large-scale genetic study uncovers new factors associated with a pregnancy-related liver disease
Intrahepatic cholestasis of pregnancy (ICP) affects approximately 0.2–2% of pregnant women and typically develops after 30 weeks of gestation. As the most common symptom is severe itching of the palms and the soles of the ...
1 hour ago
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Immune cell circuit restores barrier function in inflammatory bowel disease
Scientists have discovered a new protective communication circuit between specialized immune cells in the intestines, a circuit that may be therapeutically targeted to improve inflammatory bowel disease outcomes, according ...
4 hours ago
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Mapping immune cell interactions in gut tissue reveals changes in ulcerative colitis
In a new study published in Science Immunology, researchers at King's College London looked at a type of tissue important for the immune response called gut-associated lymphoid tissue (GALT), which is located within the lining ...
5 hours ago
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Expanding the evidence for behavioral interventions in gastroenterology
The Division of Gastroenterology and Hepatology at Feinberg has a distinct strength in understanding how behavior and lifestyle influence gastrointestinal (GI) health. Through its work and in collaboration with the Northwestern ...
9 hours ago
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Your gut talks to your liver: Study reveals how microbes influence liver function through DNA 'switches'
A study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function ...
22 hours ago
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Genetic marker may flag severe IBD earlier in some patients
In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker associated with more severe ulcerative colitis and Crohn's disease—the major forms of IBD.
23 hours ago
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Crohn's atlas maps gene shifts across more than 50 gut cell types
A detailed cellular study of Crohn's disease has mapped how gene activity changes across more than 50 cell types in the gut. The study provides an open resource of the genes that characterize each cell type and those whose ...
Jun 15, 2026
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Cohabiting people share about a quarter of their gut and oral microbiota, study finds
People who live together share more oral and gut microbes with each other than with other people in their communities, according to a study published in Cell Press Blue. This was true regardless of the cohabitants' relationships—siblings, ...
Jun 15, 2026
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Blueberry-size capsule tracks core temperature from inside the body
In a hospital or at home, temperatures are usually taken using an oral or forehead thermometer, but these do not always accurately reflect core body temperature. Measuring core temperature from within the body could make ...
Jun 15, 2026
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Dietary fiber supplement shows promise for fatty liver, with effects linked to gut microbiota
A new study is the first to investigate the effects of prebiotic xylo-oligosaccharides (XOS) on fatty liver in humans. The findings suggest the fiber supplement may reduce harmful metabolic byproducts in the gut and thereby ...
Jun 15, 2026
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Long naps may increase the risk of chronic liver disease in people with diabetes
People with type 2 diabetes who nap longer than 30 minutes every day, regardless of their sleep patterns at night, increase their risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD), according ...
Jun 15, 2026
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How H. pylori uses extracellular vesicles to drive stomach cancer
Scientists at the Hudson Institute of Medical Research have discovered how Helicobacter pylori, the bacterium responsible for most stomach cancers and peptic ulcers, delivers a key disease-causing protein into human cells. ...
Jun 15, 2026
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Novel electronic health record-based marker can identify at-risk transplant patients and reduce organ rejection
A new multicenter study led by researchers at the Icahn School of Medicine at Mount Sinai suggests that a novel electronic health record-based marker can help clinicians identify transplant patients at high risk for organ ...
Jun 15, 2026
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Why some newborn flies sleep instead of eat: Gut blockage offers clues to brain-gut signals
The gut does much more than just digest food. Researchers at the University of Basel have discovered a surprising link between gut function, feeding and sleep in fruit flies. Their study adds to growing evidence that the ...
Jun 14, 2026
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Megacolon: When constipation becomes something more serious
The colon is about one and a half meters long and plays a vital role in moving waste through the body. In rare cases, it can become so stretched that it begins to lose its ability to work properly, like an elastic band that ...
Jun 14, 2026
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Sugar-free diets may disrupt the gut microbiome, animal study indicates
Eliminating sugar from your diet may be more detrimental than previously thought, according to an animal study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago.
Jun 13, 2026
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Prenatal health and early diet may shape fatty liver risk, study suggests
The accumulation of excess fat in the liver is not solely a consequence of the combined effects of hereditary and adult lifestyle-related factors. A new study by researchers at Tampere University and the University of Eastern ...
Jun 13, 2026
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Engineers find a way to deliver drugs directly to the esophagus
There are few treatment options available for people with disorders of the esophagus. Delivering drugs directly to this part of the body is difficult, so patients are usually treated with systemic drugs, which can have unwanted ...
Jun 12, 2026
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COPA mutations reveal alternative trigger for small intestine tumors
A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have shown that disruption of this pathway is a defining feature of many ...
Jun 12, 2026
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Refined pseudo-germ-free mice reveal gut microbes' role in pancreatic cancer
Researchers at National Taiwan University refined a pseudo-germ-free mouse model to make gut microbiome studies safer for mice and more reliable. Using this model, they found that antibiotic-driven changes in gut microbes ...
Jun 12, 2026
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Gut microbes unlock hormone signaling that regulates gut movement, study suggests
Millions of people worldwide are periodically or chronically affected by gut-related conditions, such as irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD) and gastroenteritis. Uncovering the physiological ...
Gut bacteria molecule may ease colitis by slowing cellular energy production
Enterobactin, a molecule produced by gut bacteria, may hold a surprising key to reducing intestinal inflammation—not by attacking the immune system directly, but by temporarily slowing down the cell's own energy production.
Jun 11, 2026
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Ultraprocessed grains linked to higher risk for developing IBD
Ultraprocessed grain intake is associated with an increased risk for developing inflammatory bowel disease (IBD), according to a study published in the June issue of the American Journal of Gastroenterology.
Jun 11, 2026
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Decades-old puzzle solved as scientists uncover cause of inflammatory bowel disease
Researchers at the Nuffield Department of Medicine, University of Oxford, together with Newcastle University's Translational and Clinical Research Institute and the Department of Immunology at Cambridge University Hospitals ...
Jun 10, 2026
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