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Gastroenterology news
A hidden army of zombie immune cells may drive fatty liver disease, inflammation and aging
UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation ...
2 hours ago
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Confirmed precursor to commonest form of esophageal cancer offers opportunities to catch the disease early
Scientists have found the strongest evidence to date that a condition known as Barrett's esophagus is the starting point for all cases of esophageal adenocarcinoma—the most common type of esophageal cancer in the developed ...
2 hours ago
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Genetic atlas reveals how human liver cells divide their labor
If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first stops would no doubt be ...
16 hours ago
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Gut microbiome serves as key driver of bacterial infection outcomes in fatty liver disease
A research team led by the University of California, Irvine's Joe C. Wen School of Population & Public Health has uncovered a critical biological link explaining why individuals with metabolic dysfunction-associated steatotic ...
11 hours ago
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From benign growth to pancreatic cancer: New study shows how the switch gets flipped
As we age, our cells accumulate genetic changes—mutations—some of which open the door to cancer. Scientists call these mutations "oncogenic," meaning "tumor-producing." By our senior years, we each may harbor as many as 100 ...
13 hours ago
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Poor hygiene and food handling practices increase the risk of bacterial outbreaks in Brazilian households
A significant number of Brazilians engage in improper food hygiene and handling practices at home. Examples include washing meat in the kitchen sink and failing to properly wash vegetables. These findings were revealed by ...
9 hours ago
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Why bowel movements start: Newly identified ATP signaling may explain the colon's strongest contractions
Giant migrating contractions (GMCs) are powerful waves of colonic movement that propel intestinal contents toward the anus and are essential for defecation. Yet despite their physiological importance, the mechanisms that ...
15 hours ago
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Modern lifestyles may be affecting how our bodies recycle estrogen
Our industrialized, modern lifestyles may be increasing how much estrogen (the female sex hormone) gets recycled in our bodies, according to a study published in the journal Proceedings of the National Academy of Sciences. ...
GLP-1 medicine improves liver health independent of weight loss, study finds
Researchers at Toronto's Sinai Health have found that semaglutide—the active ingredient in popular weight loss drugs that mimic the gut hormone GLP-1—acts directly on a subset of liver cells to improve organ function and ...
Apr 14, 2026
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Expanding access to palliative care for patients with advanced liver disease
Advanced liver disease (ALD) occurs when significant scarring causes the liver to lose function. Patients with ALD often have serious health challenges but have limited access to palliative care that could improve their quality ...
Apr 13, 2026
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Epigenetic changes at birth are associated with an infant's microbiome and neurodevelopment
The gut microbiome and epigenetics—molecular switches that turn genes on or off—are intertwined, and both contribute to neurodevelopment, finds a study published in Cell Press Blue. The researchers showed that epigenetic ...
Apr 10, 2026
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Negative effects of artificial sweeteners may pass on to next generation, study suggests
Health organizations are starting to raise concerns about the potential long-term impacts of artificial sweeteners, which taste sweet but—unlike sugar—contain no calories, suggesting they could interfere with energy metabolism ...
Apr 10, 2026
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Should people over 75 continue colonoscopies?
The American Cancer Society recommends screening for colorectal cancer in adults beginning at age 45 and continuing through age 75. However, adults over the age of 75 with a history of precancerous polyps—also known as adenomas—are ...
Apr 10, 2026
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Why fatty liver results can mislead: RNA changes often fail to predict proteins
Fatty liver is an increasingly common disease that can progress toward more severe forms, involving inflammation, fibrosis, and, in some cases, cirrhosis and liver cancer. While it is known that a high-fat diet alters gene ...
Apr 9, 2026
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Rethinking the gut microbiome: Health is not about staying the same, say experts
At any moment, your body hosts trillions of microorganisms, on your skin, in your hair, and especially in your gut. Together they form the microbiome. It plays a crucial role in digestion, immunity, and overall health. Yet ...
Apr 9, 2026
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Gut bacteria linked to levels of latent HIV
The composition of gut bacteria appears to be associated with how much latent HIV remains in the blood of people receiving antiretroviral therapy. This is shown in a new study from Karolinska Institutet, published in Gut ...
Apr 9, 2026
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Study finds sex- and race-based disparities in IBS diagnosis rates among US adults
A national survey study led by UCLA Health and Cedars-Sinai Medical Center has found significant disparities in how irritable bowel syndrome (IBS) is diagnosed across sex and racial groups in the U.S., with men and Black ...
Apr 9, 2026
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Some common IBS treatments are linked to a higher risk of death, say study
A large, long-term study led by Cedars-Sinai Health Sciences University investigators suggests that some medications commonly prescribed to treat irritable bowel syndrome (IBS)—including antidepressants—may be associated ...
Apr 8, 2026
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Gut inflammation may rewire the 'second brain,' triggering lasting motility problems
Research by Milena Bogunovic, MD, Ph.D., associate professor of pathology, sheds light on how inflammation in the gastrointestinal (GI) tract, such as that associated with inflammatory bowel disease (IBD), can lead to long-lasting ...
Apr 8, 2026
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Loss of microbiota alters the profile of cells that protect the intestinal wall, experiments reveal
A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and intestinal cells. The study, ...
Apr 8, 2026
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Can gluten pass through a kiss? New data are reassuring
For people living with celiac disease, the fear of gluten exposure can extend beyond food—sometimes even into moments of intimacy. A new study published in Gastroenterology offers reassuring news: while gluten can be transferred ...
Apr 8, 2026
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Are your bathroom habits normal? New book addresses concerns
When you're an expert on the gut, you're used to conversations others might shy away from. So a book on pooping and what can go wrong in the process is on brand for Trisha Pasricha, a second-generation gastroenterologist ...
Apr 7, 2026
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Researchers identify potential therapeutic target for alcohol-associated liver disease and alcohol use disorder
Scientists have identified a particular protein in the body that may influence the progression of alcohol-associated liver disease and drinking behavior. The protein aquaporin 9 (AQP9) helps liver cells absorb and excrete ...
Apr 7, 2026
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AI tool can predict Barrett's esophagus recurrence after therapy with 90% accuracy
A new artificial intelligence (AI)-based tool shows promise for improving surveillance in patients treated with endoscopic eradication therapies for Barrett's esophagus (BE)-related dysplasia and early esophageal adenocarcinoma. ...
Apr 7, 2026
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Researchers start to clarify the likelihood of recovery after alcohol-associated hepatitis
Returning to drinking after alcohol-associated hepatitis (AH) is closely related to recurrent liver disease and death. Of those hospitalized for AH, 30% die within 90 days. Among the survivors, alcohol use is key to outcomes. ...
Apr 7, 2026
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