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Gastroenterology news
Berberine as a natural Ozempic? An analysis of a popular myth
In recent years, berberine has increasingly appeared in the public sphere as a "natural way" to improve metabolism. In social media, it is sometimes compared to incretin drugs and even referred to as "plant-based Ozempic." ...
Mar 13, 2026
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Study finds CDK4/6 plus EGFR blockade kills pancreatic cancer cells without KRAS drugs
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 inhibition offers an indirect ...
Mar 13, 2026
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Uncovering a key signaling pathway linking liver cancer and fibrosis
New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better treatment strategies, report researchers from Institute of Science Tokyo. Through a comprehensive analysis ...
Mar 13, 2026
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New strategy intercepts pancreatic cancer by eliminating microscopic lesions before they become cancer
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors. Using an experimental therapy to target microscopic precancerous lesions in the ...
Mar 12, 2026
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High-fat diet-linked dysbiosis may send gut bacteria to the brain via vagus nerve
Gut dysbiosis caused by a high-fat diet can allow bacteria to move from the gut to the brain in mice, according to a new study by David Weiss and Arash Grakoui from Emory University, U.S., and colleagues published in the ...
Mar 12, 2026
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Gut health supplement relieves arthritis pain, finds new study
A new study has found that a prebiotic fiber supplement reduced pain, improved grip strength, and lowered pain sensitivity in people with knee osteoarthritis (OA)—with far fewer dropouts than a digital physiotherapy program. ...
Mar 12, 2026
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Enhancing gut-brain communication reverses cognitive decline and improves memory formation in aging mice
Although we've all experienced the sensation of "eating" with our eyes and noses before food meets mouth, much less is known about the information superhighway, known as the vagus nerve, that sends signals in the opposite ...
Mar 11, 2026
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Antibiotics can affect the gut microbiome for several years, study shows
Antibiotic treatments can affect the composition of the community of bacteria living in the gut, known as the gut microbiome, for a long time. A new study shows that certain types of antibiotics can be linked to changes in ...
Mar 11, 2026
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An experimental model reproduces creeping fat associated with Crohn's disease and facilitates its study
A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and the Institut de Recerca Biomèdica Catalunya Sud (IRB CatSud, formerly IISPV) has published a study in the journal Inflammatory Bowel Diseases ...
Mar 11, 2026
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Seaweed has the potential to create a shield to block norovirus infection
To date, there are no approved vaccines or antiviral treatments for human norovirus, the leading cause of acute gastroenteritis outbreaks worldwide with more than 685 million infections each year. Norovirus is highly contagious ...
Mar 11, 2026
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Fructose-fed mice with low testosterone gained liver weight, but antibiotics blunted it
Low testosterone in itself can cause a variety of health problems, but the addition of a poor diet can exacerbate certain conditions. Metabolic dysfunction-associated steatotic liver disease (MASLD) is one example that approximately ...
Mar 11, 2026
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How voluntary exercise reshapes tryptophan metabolism through the gut microbiota
Something happens when a rat starts running. Not just the obvious things, the faster heart, the warming muscles, the rhythmic percussion of paws against the wheel. Something quieter. Something that begins in the coiled darkness ...
Mar 10, 2026
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Gut bacteria drive process that protects colon tissue, study shows
The gut microbiome—the trillions of bacteria and other microbes that inhabit the gastrointestinal tract—drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led ...
Mar 10, 2026
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Specific gut bacteria species linked to muscle strength
A species of gut bacteria called Roseburia inulinivorans is specifically associated with human muscle strength and improved muscular performance in mice, finds research published online in the journal Gut.
Mar 10, 2026
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Gut motility increases within minutes of physical activity, research shows
Gut health plays a vital role in overall well-being, with constipation remaining one of the most widespread and frustrating digestive issues that people face today. It affects individuals of all ages and backgrounds, leading ...
Mar 10, 2026
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Clotting protein presents a potential target in pancreatic cancer
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that depleting a clotting protein made by the liver could slow down pancreatic cancer. The research, recently published in ...
Mar 10, 2026
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Hidden blood mutations drive severe inflammatory bowel disease, but a new treatment target is in sight
Indiana University School of Medicine scientists have uncovered new evidence that an age-related blood condition may contribute to inflammatory bowel disease (IBD). Their findings suggest that a new drug strategy targeting ...
Mar 9, 2026
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Stay or stray? Why some gut microbes persist after fecal transplants
Scientists have identified why some gut microbes successfully stay in the gut after fecal transplants, while others are much more transient. The King's College London discovery could help make the treatment—which involves ...
Mar 9, 2026
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Heart and metabolic risk factors more strongly linked to liver fibrosis in women than men, study finds
Women with certain cardiometabolic risk factors, including type 2 diabetes and high waist circumference, face a greater increase in risk for liver fibrosis than men with the same risk factors. The study, just published in ...
Mar 9, 2026
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Human intestinal cell model enables precise detection of drug-induced barrier damage
Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity during the preclinical stage ...
Mar 9, 2026
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What does the appendix do? Biologists explain the complicated evolution of this inconvenient organ
Most people know only two things about the appendix: You don't need it—and if it bursts, you need surgery fast.
Mar 9, 2026
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A virus hiding inside bacteria may help explain colorectal cancer
The gut bacterium Bacteroides fragilis has long presented researchers with a paradox. It has been associated with colorectal cancer, yet it also lives quite happily in most healthy people. A study by a Danish research team ...
Mar 8, 2026
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Short bowel syndrome has no drugs: A new compound could cut liver risk
When parts of the small intestine are diseased or die, the treatment can involve surgically removing the affected tissue. Although lifesaving, the procedure—referred to as a radical small bowel resection—can lead to long-term ...
Mar 6, 2026
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Why your gut microbiome and heart may be closer than you think
The gut microbiome plays an important role in many aspects of health, from digestion and immune function to metabolic balance and neurological processes.
Mar 6, 2026
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AI blood test detects early pancreatic cancer with up to 94% accuracy
A team of researchers from Taiwan has developed PanMETAI, an AI-powered platform that analyzes metabolic fingerprints in a simple blood sample to detect pancreatic cancer at its earliest stages—when treatment is most effective—achieving ...
Mar 5, 2026
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