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Gastroenterology news
'Junk DNA' may help defend against colorectal cancer
For decades, large portions of the human genome were labeled "junk DNA." New research from Western University and London Health Sciences Centre Research Institute (LHSCRI) suggests these overlooked sequences may help protect ...
6 hours ago
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Heart disease risk tied to certain molecules made by gut microbes
In a study involving data from thousands of people, the risk of a new coronary heart disease diagnosis was statistically associated with bloodstream levels of nine specific molecules that are produced by gut microbes. Danxia ...
7 hours ago
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Detection of bowel cancer marker in wastewater may offer new early warning system
Detection of a bowel cancer marker (CDH1) in wastewater may offer a new community-level early warning system for the disease, suggests a proof-of-concept study published in the Journal of Epidemiology and Community Health. ...
2 hours ago
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Recommendations presented for management of hepatic encephalopathy
In a clinical guideline issued by the American College of Gastroenterology and published in the March issue of the American Journal of Gastroenterology, recommendations are presented for the diagnosis and management of hepatic ...
1 hour ago
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Recommendations developed for faltering weight in children
In a clinical practice guideline issued by the American Academy of Pediatrics, in partnership with the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, recommendations are presented for the ...
2 hours ago
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The Alzheimer's gut-brain link: How butyrate could curb amyloid-β buildup and inflammation
Alzheimer's disease (AD) is a neurodegenerative disease that causes progressive memory loss and a significant decline in mental functions. Past studies have shown that people with AD exhibit a buildup of a protein called ...
Early life stress linked to long-lasting digestive issues
Early life stress may lead to digestive issues later in life, driven by changes in the gut and sympathetic nervous systems, according to a new study published in the journal Gastroenterology.
Mar 16, 2026
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The hidden signals of Crohn's disease: Why remission is not recovery
Imagine a patient with Crohn's disease—after months of flares, they are finally in clinical remission. Their biomarkers are stable, their pain has subsided, and their doctors are satisfied. They are on the gold standard ...
Study maps cellular mechanisms driving fibrosis in Crohn's disease
Researchers at the Earlham Institute, the University of Edinburgh and Heriot-Watt University analyzed gut cells to understand the drivers behind fibrosis, a common complication in Crohn's disease affecting 10–20% of patients. ...
Mar 16, 2026
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The gut can drive age-associated memory loss, research reveals
We become forgetful as we age. This is often seen as a universal truth, but in fact it is far from universal: some people remain incredibly sharp at 100 years old, while others experience memory loss starting in middle age.
Mar 15, 2026
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'Bugs delivering drugs': A new approach to colorectal cancer treatment using common food-borne bacteria
Baylor University researchers have developed a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells. Michael S. VanNieuwenhze, Ph.D., FRSC, ...
Mar 15, 2026
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Study maps three biological routes for gastric cancer beyond H. pylori
A study in Gut shows that gastric cancer is shaped by complex interactions between environmental exposure, microbes, host, and tumor biology. The findings reveal distinct cancer routes and targets linked to prognosis and ...
Mar 15, 2026
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Berberine as a natural Ozempic? An analysis of a popular myth
In recent years, berberine has increasingly appeared in the public sphere as a "natural way" to improve metabolism. In social media, it is sometimes compared to incretin drugs and even referred to as "plant-based Ozempic." ...
Mar 13, 2026
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Study finds CDK4/6 plus EGFR blockade kills pancreatic cancer cells without KRAS drugs
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 inhibition offers an indirect ...
Mar 13, 2026
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Uncovering a key signaling pathway linking liver cancer and fibrosis
New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better treatment strategies, report researchers from Institute of Science Tokyo. Through a comprehensive analysis ...
Mar 13, 2026
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New strategy intercepts pancreatic cancer by eliminating microscopic lesions before they become cancer
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors. Using an experimental therapy to target microscopic precancerous lesions in the ...
Mar 12, 2026
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High-fat diet-linked dysbiosis may send gut bacteria to the brain via vagus nerve
Gut dysbiosis caused by a high-fat diet can allow bacteria to move from the gut to the brain in mice, according to a new study by David Weiss and Arash Grakoui from Emory University, U.S., and colleagues published in the ...
Mar 12, 2026
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Gut health supplement relieves arthritis pain, finds new study
A new study has found that a prebiotic fiber supplement reduced pain, improved grip strength, and lowered pain sensitivity in people with knee osteoarthritis (OA)—with far fewer dropouts than a digital physiotherapy program. ...
Mar 12, 2026
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Enhancing gut-brain communication reverses cognitive decline and improves memory formation in aging mice
Although we've all experienced the sensation of "eating" with our eyes and noses before food meets mouth, much less is known about the information superhighway, known as the vagus nerve, that sends signals in the opposite ...
Mar 11, 2026
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Antibiotics can affect the gut microbiome for several years, study shows
Antibiotic treatments can affect the composition of the community of bacteria living in the gut, known as the gut microbiome, for a long time. A new study shows that certain types of antibiotics can be linked to changes in ...
Mar 11, 2026
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An experimental model reproduces creeping fat associated with Crohn's disease and facilitates its study
A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and the Institut de Recerca Biomèdica Catalunya Sud (IRB CatSud, formerly IISPV) has published a study in the journal Inflammatory Bowel Diseases ...
Mar 11, 2026
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Seaweed has the potential to create a shield to block norovirus infection
To date, there are no approved vaccines or antiviral treatments for human norovirus, the leading cause of acute gastroenteritis outbreaks worldwide with more than 685 million infections each year. Norovirus is highly contagious ...
Mar 11, 2026
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Fructose-fed mice with low testosterone gained liver weight, but antibiotics blunted it
Low testosterone in itself can cause a variety of health problems, but the addition of a poor diet can exacerbate certain conditions. Metabolic dysfunction-associated steatotic liver disease (MASLD) is one example that approximately ...
Mar 11, 2026
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How voluntary exercise reshapes tryptophan metabolism through the gut microbiota
Something happens when a rat starts running. Not just the obvious things, the faster heart, the warming muscles, the rhythmic percussion of paws against the wheel. Something quieter. Something that begins in the coiled darkness ...
Mar 10, 2026
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Gut bacteria drive process that protects colon tissue, study shows
The gut microbiome—the trillions of bacteria and other microbes that inhabit the gastrointestinal tract—drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led ...
Mar 10, 2026
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