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Gastroenterology news
Trial results show no survival benefit with the use of proton therapy in patients with advanced hepatocellular carcinoma
Initial results of the NRG Oncology NRG-GI003 clinical study comparing proton and photon therapy for patients with advanced hepatocellular carcinoma (HCC) indicate that proton therapy did not improve the primary objective ...
Oct 4, 2026
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Too little salt may hurt memory just as badly as too much
Salt can make or break a dish. A little too much or too little can throw everything off, leaving even the most luxurious ingredients tasting off. But get the balance right, and salt can bring out the flavor in even the simplest ...
Magnetically controlled capsule shows promise for investigating hard-to-reach regions of the small intestine
A small capsule could change how we study the microbiome of the small intestine. A team led by researchers at the University of Tokyo has created a pill-shaped device designed to take samples from the small intestine using ...
Oct 2, 2026
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Metabolite-inspired compounds show promise for ulcerative colitis drug discovery
Two structurally modified compounds derived from an anti-inflammatory metabolite demonstrated enhanced anti-inflammatory activity in experimental ulcerative colitis in mice and human tissue, offering an underexplored drug ...
Oct 2, 2026
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Colorectal cancer on the rise in adolescent patients, data analysis finds
Rates of advanced-stage colorectal cancer are climbing in young patients, highlighting a need for increased vigilance, according to data presented during the American Academy of Pediatrics 2026 National Conference & Exhibition ...
Oct 2, 2026
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Endurance exercise rewires liver metabolism differently based on sex, study suggests
Exercise benefits nearly every part of the body, including the liver and metabolism. But new research from the University of Missouri School of Medicine suggests those benefits may not look the same in males and females. ...
Oct 1, 2026
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How damaged mitochondria may contribute to liver disease
Mitochondria supply cells with energy, and they also play an important role in metabolism. The Institute of Biochemistry and Molecular Biology I at Heinrich Heine University Düsseldorf (HHU) and University Hospital Düsseldorf ...
Oct 1, 2026
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New recommendations for serrated polyposis syndrome
New consensus recommendations by the U.S. Multi-Society Task Force (MSTF) on Colorectal Cancer (CRC) address serrated polyposis syndrome (SPS), which is the most common gastrointestinal polyp syndrome yet is widely underrecognized ...
Oct 1, 2026
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Before the first bite: A missing gut protein may set the stage for peanut allergy
For most people, a peanut butter sandwich poses no threat. But for the roughly 1.6 million children in the United States with peanut allergy, exposure can trigger a life-threatening reaction. Why some individuals are susceptible ...
Oct 1, 2026
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Skipping sweets during antibiotic treatment may help protect the gut microbiome
A new study by researchers at City of Hope suggests eating less sugar could protect the microbiome during antibiotic treatment. The study followed patients with blood cancer undergoing an intensive treatment called allogeneic ...
Sep 30, 2026
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Serum 25(OH)D may serve as a biomarker of disease activity in IBD
For patients with inflammatory bowel disease (IBD), serum 25-hydroxyvitamin D (25[OH]D) may serve as a biomarker for disease activity, according to a study published online Sept. 10 in the Journal of Clinical Medicine.
Sep 30, 2026
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Promising therapy for fatty liver disease reduces fat, inflammation, and scarring in preclinical models
For millions of people living with metabolic dysfunction-associated steatohepatitis (MASH), treatment options remain limited. The progressive form of fatty liver disease develops when excess fat accumulates in the liver, ...
Sep 29, 2026
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Distinct gut microbiome patterns found in five cancer groups and in early-onset cancers
Mayo Clinic researchers have discovered distinct gut microbiome patterns in adults 50 or younger with colorectal and breast cancers compared with those diagnosed later in life—one of several findings from an analysis of stool ...
Sep 29, 2026
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Microplastics clog liver immune cells, driving fat buildup in mice
Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it. These ...
Sep 29, 2026
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Aspirin did not prevent recurrence after liver metastasis surgery, study shows
Colon and rectal cancer often spread to the liver. In some patients, the metastases can be surgically removed or destroyed using local treatment with the aim of curing the disease. Despite this, the cancer often returns. ...
Sep 29, 2026
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Stomach bacterium hijacks healing signals to drive precancerous changes, study finds
Stomach cancer is one of the deadliest forms of cancer. Unlike many other types of cancer, however, one of its main causes is well known: chronic infection with the bacterium Helicobacter pylori. A team headed by Charité—Universitätsmedizin ...
Sep 28, 2026
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Experimental mRNA therapy dramatically extends treatment window for acetaminophen overdose in preclinical models
When a patient arrives at the hospital with an acetaminophen overdose, it's often a race against the clock. The only FDA-approved antidote for overdose-related liver injury, N‑acetylcysteine, must be administered within hours ...
Sep 28, 2026
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High-salt diet may drive fatty liver disease differently in lean people
Fatty liver disease is commonly associated with obesity, yet a growing number of people with normal body weight develop a severe form of the condition. Scientists at Duke-NUS Medical School have identified a distinct mechanism ...
Sep 28, 2026
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Gut microbiome can reveal risk of type 2 diabetes
Changes in the composition of gut bacteria could provide an early warning of type 2 diabetes (T2D), according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) ...
Sep 27, 2026
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Experimental gene-silencing therapy offers hope for hepatitis B cure
Chronic hepatitis B is a long-lasting condition caused by the hepatitis B virus (HBV) that affects about 240 million people worldwide. Most people infected show no symptoms for years, but when symptoms do appear, they can ...
How the treatment of interleukin-6-driven diseases can be refined
Interleukin-6 (IL-6) is a contradictory molecule in immunology. It helps the liver regenerate after injury and protects against infections, yet it also drives chronic inflammation in rheumatic diseases, inflammatory bowel ...
Sep 25, 2026
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Why some patients may develop severe intestinal inflammation after CAR-T therapy
Researchers at the Icahn School of Medicine at Mount Sinai have identified biological mechanisms that may contribute to CAR-T cell-associated enterocolitis, a serious inflammatory condition of the intestine that can occur ...
Sep 25, 2026
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Steatotic liver disease risk scores compared for predicting cirrhosis
For patients with steatotic liver disease (SLD), the steatosis-associated fibrosis estimator (SAFE) score demonstrated the greatest net benefit for predicting cirrhosis, according to a study published online Sept. 21 in JAMA ...
Sep 25, 2026
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Appendectomy for appendicitis associated with 58% lower colorectal cancer risk than antibiotics alone
Patients who underwent an appendectomy for acute appendicitis had a significantly lower subsequent risk of colorectal cancer than similar patients treated with antibiotics alone, according to new research.
Sep 25, 2026
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