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Gastroenterology news
Engineers find a way to deliver drugs directly to the esophagus
There are few treatment options available for people with disorders of the esophagus. Delivering drugs directly to this part of the body is difficult, so patients are usually treated with systemic drugs, which can have unwanted ...
Jun 12, 2026
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COPA mutations reveal alternative trigger for small intestine tumors
A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have shown that disruption of this pathway is a defining feature of many ...
Jun 12, 2026
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Refined pseudo-germ-free mice reveal gut microbes' role in pancreatic cancer
Researchers at National Taiwan University refined a pseudo-germ-free mouse model to make gut microbiome studies safer for mice and more reliable. Using this model, they found that antibiotic-driven changes in gut microbes ...
Jun 12, 2026
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Gut microbes unlock hormone signaling that regulates gut movement, study suggests
Millions of people worldwide are periodically or chronically affected by gut-related conditions, such as irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD) and gastroenteritis. Uncovering the physiological ...
Ultraprocessed grains linked to higher risk for developing IBD
Ultraprocessed grain intake is associated with an increased risk for developing inflammatory bowel disease (IBD), according to a study published in the June issue of the American Journal of Gastroenterology.
Jun 11, 2026
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Gut bacteria molecule may ease colitis by slowing cellular energy production
Enterobactin, a molecule produced by gut bacteria, may hold a surprising key to reducing intestinal inflammation—not by attacking the immune system directly, but by temporarily slowing down the cell's own energy production.
Jun 11, 2026
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Decades-old puzzle solved as scientists uncover cause of inflammatory bowel disease
Researchers at the Nuffield Department of Medicine, University of Oxford, together with Newcastle University's Translational and Clinical Research Institute and the Department of Immunology at Cambridge University Hospitals ...
Jun 10, 2026
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GLP-1s may alleviate depression through the microbiome, mouse study suggests
Some people taking GLP-1 drugs for diabetes and obesity experience mental health benefits—particularly a decrease in symptoms of depression. In a mouse model study published in Cell Host & Microbe, researchers report that ...
Jun 10, 2026
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Sugary beverages may raise your risk of liver cancer
If you regularly drink soda or other sugary beverages, a new study may give you a reason to cut back.
Jun 10, 2026
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Why eating in the middle of the night can cause gastrointestinal issues
Eating when the body is normally asleep appears to desynchronize the circadian clocks of different cell types in the intestines, a UT Southwestern Medical Center study suggests. The findings, published in PNAS, could help ...
Jun 9, 2026
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Celiac risk may begin with weaker helper T cells, not just overactive immunity
New research from the Snow Center for Immune Health is challenging long-held assumptions about autoimmune disease, revealing that celiac disease may be driven not just by an overactive immune system, but by subtle defects ...
Jun 9, 2026
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Physician–researcher's work yields landmark five-year data for Crohn's disease drug
A physician–scientist and national leader in inflammatory bowel disease at the University of Cincinnati has led the publication of landmark five-year efficacy and safety data for guselkumab, a biologic therapy for moderately ...
Jun 9, 2026
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Fiber for gut health: Expert explains why it's best to eat more than one kind, build up gradually
Fiber is an essential part of a healthy diet. By eating a variety of plant-based foods, increasing fiber intake gradually and staying well hydrated, you can support gut health and overall well-being while making fiber goals ...
Jun 9, 2026
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Healthy pancreas shows layered ducts and rare cells tied to aggressive tumors
Scientists at the Free University of Brussels (VUB) have taken a major step forward in pancreatic cancer research. By mapping a healthy pancreas in detail down to the cellular level, they discovered that specific, rare cells ...
Jun 9, 2026
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How often do people pass gas? There's now an app for that
Flatulence, or farting, is something people often joke about or find embarrassing when it happens unexpectedly. It is, however, an essential bodily function that allows the digestive system to keep pressure within the intestinal ...
A good night's sleep begins with healthy gut bacteria. Here's how to look after yours
It's no accident that we spend a third of our lives asleep. It is essential to our health, and even animals for whom resting is complicated—such as aquatic mammals that need to surface to breathe, or birds that go up to 10 ...
Jun 7, 2026
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New noninvasive tool may allow early detection of dangerous intestinal disease in preemies
A new noninvasive technology, called broadband optical spectroscopy (BOS), has promise for reliably detecting necrotizing enterocolitis (NEC) in premature infants at earlier stages, before this devastating intestinal disease ...
Jun 7, 2026
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Drug nearly doubles survival in advanced pancreatic cancer—how daraxonrasib overcame an 'undruggable' disease
For a long time, the likelihood of surviving pancreatic cancer has been extremely low. For patients who were diagnosed with metastatic pancreatic cancer between 2015 and 2021, about 97% died within five years of their diagnosis.
Jun 6, 2026
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Clarifying the interplay between host and gut microbiota in selenium metabolism
Selenium (Se) is an essential trace mineral found in everyday dietary items, such as seafood, meat, and whole grains. Our bodies depend on it for many biological functions, from the synthesis of antioxidant enzymes to immune ...
Jun 6, 2026
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Food insecurity linked to gut microbiome changes in children
Food insecurity may leave a measurable biological signature in the gut microbiome of children, according to new research presented at ASM Microbe 2026.
Jun 6, 2026
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FDA approves first treatment for chronic hepatitis delta virus infection
The U.S. Food and Drug Administration has approved Hepcludex (bulevirtide‐gmod) injection to treat chronic hepatitis delta virus (HDV) infection in adults without cirrhosis or compensated cirrhosis. Approval of Hepcludex ...
Jun 5, 2026
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Scientists recreate enterovirus infection in a new model of the human intestine
A miniaturized, biomimetic model of the human intestine has successfully reproduced long-term enterovirus A71 (EV-A71) infection, report researchers from Science Tokyo. Using this innovative platform, they shed light on how ...
Jun 4, 2026
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2.2 million-cell atlas reveals how genes drive inflammatory bowel disease risk
Scientists have created the most detailed cell map to date showing how genetic variation influences inflammatory bowel disease (IBD), revealing the specific cells and genes that drive the disease. Published in Nature, the ...
Jun 3, 2026
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A 3D printed stent, shaped like a lily, could speed recovery after weight-loss surgery
Each year, about 250,000 Americans undergo sleeve gastrectomy, one of the most common weight-loss operations in the United States. For most patients, recovery is uneventful. But for a small share—between 1% and 3% in routine ...
Jun 3, 2026
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How culture, stress, and social life may shape gut health
Abdominal pain before an important exam, nausea during intense stress, or sudden intestinal problems following difficult life experiences—many people regard such symptoms as a temporary bodily reaction. However, a growing ...
Jun 3, 2026
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