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Gastroenterology news
Oncology & Cancer
Gut microbes may hold key to understanding how exercise boosts cancer immunotherapy response
A new study from the University of Pittsburgh shows for the first time how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.
9 hours ago
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Inflammatory disorders
Scientists reveal how a key inflammatory molecule triggers esophageal muscle contraction
A research group has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth muscles of the esophagus.
12 hours ago
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Healthy plant-based diet may help protect against inflammatory bowel disease
A large prospective study published in Molecular Nutrition and Food Research reveals that a healthy plant-based diet is linked with a reduced risk of inflammatory bowel disease.
17 hours ago
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LED-based imaging system could transform cancer detection in endoscopy
Gastrointestinal cancers remain among the most common forms of cancer. While endoscopy has become a cornerstone of cancer screening and diagnosis over the past two decades, the procedure still misses approximately 8% to 11% ...
Jul 8, 2025
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What's behind the enormous increase in early-onset gastrointestinal cancers?
A paper in the British Journal of Surgery indicates that early-onset gastrointestinal cancer rates are rising dramatically across the globe.
Jul 8, 2025
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Vancomycin trial shows no significant reduction in recurrent C. diff infections
University of Wisconsin–Madison–led researchers report lower yet statistically non-significant recurrence of Clostridioides difficile (C. diff) among adults given low-dose oral vancomycin during antibiotic therapy.
Nighttime pistachio snacking may reshape gut microbiome in prediabetic adults
Prediabetes affects a third of people in the United States and most of them will develop Type 2 diabetes, yet effective dietary intervention strategies remain limited. Pistachios have shown promise in improving markers of ...
Jul 7, 2025
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Stem cell-derived liver organoids show long-term growth with bile acid support
Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem cell-derived hepatic organoids, report researchers from Japan. These three-dimensional liver organoids ...
Jul 7, 2025
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Treating a common bacteria could reduce gastric cancer cases worldwide
As many as 15.6 million people born between 2008 and 2017 globally are expected to develop gastric cancer sometime in their life, suggests a study published in Nature Medicine.
Jul 7, 2025
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Crohn's disease outlook brightens as early diagnosis and new treatments show results
Crohn's disease is a serious inflammatory bowel disease (IBD) that impacts millions worldwide. The disease is chronic and highly unpredictable, manifesting symptoms such as abdominal pain, diarrhea—sometimes with blood—and ...
Jul 7, 2025
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Mediterranean or plant-based diets may help reduce risk of chronic constipation in middle- and older-age adults
The incidence of chronic constipation increases as we age. A new study from Mass General Brigham researchers compares five common diets to determine the effectiveness of preventing chronic constipation in middle- and older-age ...
Jul 7, 2025
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Online program aims to help IBD patients build body confidence
A first-of-its-kind online body image and well-being program designed to help people with Inflammatory Bowel Disease (IBD) feel more positive about their bodies has been developed by Flinders University.
Jul 7, 2025
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Missing beneficial bacteria in infant guts linked to rising asthma and allergy cases
Nearly one in four infants lacks enough healthy gut bacteria essential for training their immune systems, putting them at greater risk of developing non-communicable diseases (NCDs) such as allergies, asthma, and eczema by ...
How AI is helping researchers to demystify gut bacteria
Gut bacteria are known to be a key factor in many health-related concerns. However, the number and variety of them is vast, as are the ways in which they interact with the body's chemistry and each other.
Jul 4, 2025
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Antibody sIgM emerges as a key guardian of gut health and metabolism
A pioneering new study published in Nature Microbiology, led by J. Oriol Sunyer, professor of immunology and pathobiology at the School of Veterinary Medicine, and a team of researchers at Penn Vet and the University of New ...
Jul 3, 2025
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Exploring probiotic use for maternal gut health
A new Burnet study has examined how probiotics could potentially treat gut-related conditions in pregnant women.
Jul 3, 2025
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Unlocking the mystery behind Barrett's esophagus
A team led by researchers at Baylor College of Medicine and Washington University School of Medicine has shed light on the process that drives Barrett's esophagus formation. This condition affects the lining of the esophagus—the ...
Jul 2, 2025
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Considerable proportion of colonoscopy bowel preparation claims involve cost-sharing
A considerable proportion of bowel preparation claims for screening colonoscopy involve patient cost-sharing, according to a research letter published online June 20 in Gastroenterology.
Jul 2, 2025
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Prebiotics may treat or prevent neurological diseases by boosting brain GABA
GABA, or gamma-aminobutyric acid, is an amino acid functioning as the principal inhibitory neurotransmitter that can act on the brain to slow or stop the reception of certain signals to the brain, leading to a calmer and ...
Jul 1, 2025
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Healthy lifestyle linked to lower diverticulitis risk, irrespective of genetic susceptibility
Maintaining a healthy lifestyle—specifically, a diet rich in fiber but light on red/processed meat, regular exercise, not smoking, and sticking to a normal weight—is linked to a significantly lower risk of diverticulitis, ...
Jul 1, 2025
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AI model spots gastric cancer on routine CT scans with high accuracy, outperforming radiologists
A collaboration of leading Chinese research institutions has developed an artificial intelligence-based method called GRAPE, demonstrating high accuracy in detecting gastric cancer from routine noncontrast CT scans.
How a common metabolite worsens inflammatory bowel disease
Northwestern Medicine investigators have identified a surprising culprit in the progression of inflammatory bowel disease: a naturally occurring metabolic compound in the gut, according to a study published in Nature Immunology.
Jun 30, 2025
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Gut microbiota play pivotal role in disordered eating tied to repeated dieting, researchers find
For the first time, the gut microbiota has been shown to play a pivotal role in the risk of disordered eating behavior stemming from yo-yo dieting. Researchers conducted a preclinical study showing that repeated dieting leads ...
Jun 30, 2025
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COVID-19 pandemic linked to surge in digestive disorders, new study finds
A study led by Cedars-Sinai investigators has uncovered a significant uptick in chronic digestive disorders, like irritable bowel syndrome, during the COVID-19 pandemic. The study findings, published in the journal Neurogastroenterology ...
Jun 30, 2025
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Mapping the dairy matrix: How the physical structures in dairy foods uniquely fuel the human body
How do we determine how healthy our food is? We know now that our nutrition shouldn't just be measured in calories, or even in just macronutrients (the balance of fats, protein, and carbohydrates). An emerging body of research ...
Jun 30, 2025
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