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Gastroenterology news
Inflammatory disorders
Potential therapeutic target for mucosal healing in eosinophilic esophagitis
Researchers at Children's Hospital of Philadelphia (CHOP) identified a potential new therapeutic target for eosinophilic esophagitis (EoE), a chronic allergic inflammatory disease of the esophagus. The findings were published ...
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Immunology
Healing the gut after cancer therapy: Immune cells turn damage into repair
Regulatory T cells (Treg cells), a specialized type of immune cell, are usually seen as "peacekeepers" that prevent excessive immune attacks. Surprisingly, a new study published in Signal Transduction and Targeted Therapy ...
Nov 28, 2025
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Potential new second-line option for advanced biliary tract cancer identified
Biliary tract cancers, including intrahepatic, perihilar, and extrahepatic cholangiocarcinoma and gallbladder cancer, are among the most aggressive gastrointestinal malignancies. Treatment options remain limited once the ...
Nov 28, 2025
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Pesticides and other common chemical pollutants are toxic to 'good' gut bacteria, lab-based screening indicates
A large-scale laboratory screening of human-made chemicals has identified 168 chemicals that are toxic to bacteria found in the healthy human gut. These chemicals stifle the growth of gut bacteria thought to be vital for ...
Nov 26, 2025
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How to donate your poo to science or medicine for development of probiotics, therapeutics
When most people think about donating body parts to science or medicine, they might think of life-saving donations of organs, tissues or blood. But you can also donate your poo.
Nov 26, 2025
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ByHeart formula faces lawsuits after babies sickened with botulism
Several families have filed lawsuits against infant formula maker ByHeart, claiming its contaminated formula caused their babies to develop botulism, a rare but dangerous illness.
Nov 26, 2025
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Fighting Crohn's with algae—can it heal the gut?
The first week of December marks Crohn's & Colitis Awareness Week. Since 1990, cases of inflammatory bowel disease (IBD) have nearly doubled. It has risen fastest among those aged 15–39. IBD is a chronic inflammation of ...
Nov 26, 2025
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Alternative sweetener sorbitol linked to liver disease
Sweeteners such as aspartame, found in Equal packets, sucralose (Splenda), or sugar alcohols are often seen as healthier alternatives to food with refined sugar (glucose). But that assumption is being challenged with new ...
Nov 25, 2025
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Why the 'gut brain' plays a central role for allergies
An international research team led by scientists from Bern and Charité—Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system.
Nov 25, 2025
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A hospital-acquired bacterium can travel from lungs to gut, raising sepsis risk
A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals.
Nov 25, 2025
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HER2-targeted therapy shows promising results in rare bile duct cancers
Zanidatamab, a bispecific HER2-targeted antibody, delivered clinically meaningful and durable responses for patients with HER2-positive biliary tract cancer (BTC), according to final results from the HERIZON-BTC-01 clinical ...
Nov 25, 2025
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Liquid biopsy tool can guide early-stage gastric cancer treatment
Early-stage gastric cancer can be assessed more accurately using a new liquid biopsy tool that predicts lymph node metastasis, as reported by researchers from Science Tokyo. They developed a model that uses deoxyribonucleic ...
Nov 25, 2025
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Your gut's railway switch: How the 'second brain' decides between attack and repair
Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the ...
Nov 24, 2025
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Polyamines promote regeneration in aged intestines, study finds
The intestine is among the most regenerative tissues in the body; however, aging triggers various changes that collectively diminish its regenerative capacity.
Nov 24, 2025
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Scientists gather more evidence for presence of 'gut-brain axis'
Research on mice by scientists at the University of Manchester has shed new light on why the guts' immune system changes after a stroke and how it might contribute to gastrointestinal problems.
Nov 24, 2025
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Prebiotic in diet linked to less impulsivity in gambling rats with traumatic brain injury
Using a prebiotic to influence bacterial activity in the gut after a traumatic brain injury may help reduce impulsive behavior, one of the common symptoms to follow a moderate blow to the head, a new study in rats suggests.
Nov 24, 2025
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Study demonstrates proof of concept for preventing esophageal cancer
Trinity St James's Cancer Institute (TSJCI) researchers demonstrated the power of a structured, quality-assured Barrett's Esophagus Registry to prevent and detect early esophageal cancer.
Nov 24, 2025
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Gut microbes may have links with sleep deprivation
Sleep is one of the essential physiological needs for human survival, alongside food, water and air. But sleep is socially driven, influenced by environmental and personal factors, and a recent study suggests it may be affected ...
Nov 24, 2025
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Toxin colibactin could be fueling colorectal cancer in young adults
In the past decade, as the rate of colorectal cancer has dramatically increased among people under 50 years of age, scientists have been trying to understand why.
Nov 24, 2025
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Macrophage-killing bacterial toxin weakens the gut's defenses against ulcerative colitis
Ulcerative colitis (UC) is one of the most common inflammatory bowel diseases, a lifelong condition that can cause chronic inflammation and ulcers in the lining of the large intestine. This can lead to symptoms such as rectal ...
CT colonography cost-effective for CRC screening in Black adults
In Black adults, computed tomography colonography (CTC) is cost-effective for colorectal cancer (CRC) screening, according to a study published online Nov. 12 in Cancer Medicine.
Nov 21, 2025
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Genome-scale models can predict how the gut microbiome influences health
The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy. A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel ...
Nov 20, 2025
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Five everyday habits that could be harming your pancreas
The pancreas is essential for staying alive and healthy. This small organ sits behind the stomach and has two main jobs. It produces digestive enzymes that break down food and hormones such as insulin and glucagon that control ...
Nov 20, 2025
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Crohn's disease treatment guidance is streamlined as new therapies expand options
The American Gastroenterological Association (AGA) has released a comprehensively updated clinical guideline on the pharmacological management of moderate-to-severe Crohn's disease. The new guideline uses cutting-edge network ...
Nov 20, 2025
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Bacteria 'pills' could detect gut diseases—without the endoscope
Colonoscopies may one day have some competition—researchers report in ACS Sensors that they've developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease. ...
Nov 19, 2025
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