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Gastroenterology news
Cellular pathways that drive precancerous lesions to form pancreatic tumors identified
Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate. It begins with a reversible state called acinar-to-ductal metaplasia, where cells can heal after injury ...
23 hours ago
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Overnight machine perfusion lets liver transplants safely shift to daytime, study shows
It is safe for patients to receive a donor liver that has been intentionally preserved overnight using machine perfusion to enable a daytime transplant. This is shown by a study performed at the University Medical Center ...
Apr 3, 2026
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Could one protein play both sides? How Stard7 shifts colon cancer in different models
Alain Chariot's team has just published a study in EMBO Molecular Medicine shedding light on the unexpected role of the Stard7 protein in the development of intestinal cancers. Long regarded as a simple lipid transporter, ...
Apr 2, 2026
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How pancreatic tumors thwart an iron-driven demise
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal adenocarcinomas (PDACs) harbor ...
Apr 2, 2026
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Occasional heavy drinking may triple the risk of liver damage, research suggests
People may assume that if they drink lightly during the week or month, heavy drinking on the occasional Friday or Saturday may not cause their liver harm. New research suggests otherwise, according to a Keck Medicine of USC ...
Apr 2, 2026
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Radiation therapy improves outcomes for 'supermassive' bile duct tumors
A new study from researchers at The University of Texas MD Anderson Cancer Center demonstrates that a specialized high-dose type of radiation delivery may significantly improve outcomes for patients with large bile duct tumors ...
Apr 2, 2026
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Cause or effect? Study answers question about gene linked with colorectal cancer
A new study has answered a question that has puzzled cancer researchers for decades: Does a genetic defect found in nearly all human colorectal cancers simply accompany the disease, or does it trigger its development? A team ...
Apr 1, 2026
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How stomach cells rebuild after injury: Study uncovers key players in tissue regeneration
Researchers at Baylor College of Medicine and collaborating institutions took a closer look at how the gastrointestinal tissue repairs itself. They reveal in the Proceedings of the National Academy of Sciences key players ...
Apr 1, 2026
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Small intestinal bacterial overgrowth linked to worsening symptoms in allergic diseases
Allergies are usually associated with the immune system, genetics, and environmental factors. Increasingly, however, another element is appearing in this puzzle: the gut microbiota. A review of studies published in the International ...
Apr 1, 2026
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Celiac disease may blunt high-fiber benefits when key gut microbes are missing
Many people with celiac disease are advised to eat more fiber to support digestion and manage symptoms, either through diet or prescribed fiber supplements. New research from McMaster University shows that the benefits of ...
Mar 31, 2026
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Dental care can help cirrhosis patients avoid liver cancer, hospitalization
A healthy mouth is key to protecting the well-being of people battling liver disease, a new study reports. Veterans with early-stage cirrhosis had fewer health problems and complications—including a lower risk of liver cancer—if ...
Mar 31, 2026
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Constipation is common, but with simple changes, you can manage and even prevent it
Chances are you've experienced constipation at some point in your life. It's one of the most common gastrointestinal complaints, affecting people of all ages, genders, and backgrounds. Constipation is typically defined as ...
Mar 30, 2026
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Fatigue highly prevalent in pediatric inflammatory bowel disease
Fatigue is highly prevalent in pediatric inflammatory bowel disease (IBD), according to a study published in the January issue of Crohn's and Colitis 360.
Mar 30, 2026
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Boosting good gut bacteria population through targeted interventions may slow cognitive decline
The origin of neurodegenerative diseases like Alzheimer's or dementia isn't limited to the brain. The state of your gut can quietly set off a cycle of chronic, system-wide inflammation that nudges the brain toward cognitive ...
A new view of intestinal regeneration: What fetal reversion could mean for IBD and cancer
Dynamic switching between revival stem cells and conventional intestinal stem cells enables efficient tissue repair without exhausting the stem cell pool, report researchers from Institute of Science Tokyo. Using organoid ...
Mar 27, 2026
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Molecular test for bile duct cancer nearly doubles detection rate
When patients develop a narrowing or blockage in the bile ducts—the tubes connecting the liver, gallbladder and intestines—physicians must determine whether the cause is cancer or a benign condition. The location of these ...
Mar 27, 2026
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IBS diets don't work for everyone: New research shows why—and it's not just about the food
If you've ever tried a diet to fix gut symptoms, you'll know it can be hit or miss. One person swears it changed their life. Another follows it carefully and feels no better.
Mar 27, 2026
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Vitamin D supplements may shift immune responses to gut bacteria in IBD
Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease (IBD), according to a Mayo Clinic-led study published in Cell Reports Medicine.
Mar 26, 2026
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DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors
The dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of Science Tokyo. Using surgical specimens and patient-derived ...
Mar 26, 2026
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A machine learning model may enable liver cancer risk prediction with routine clinical information
A machine learning model that analyzes patient demographics, electronic health record data, and routine blood test results predicted a patient's risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, ...
Mar 26, 2026
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How inflammation may prime the gut for cancer
Chronic inflammation can raise a person's risk of cancer, and a new study reveals key details about how that might happen in the gut and points to better ways to identify and reduce risk. Scientists at the Broad Institute ...
Mar 25, 2026
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Fiber in whole wheat foods protects against gut inflammation in mice, research finds
Enriching the diet with wheat fiber protects mice against intestinal inflammation, according to a study published by researchers at the Institute for Biomedical Sciences (IBMS) at Georgia State University. The finding helps ...
Mar 25, 2026
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Gut-to-brain pathway explains how the immune system triggers loss of appetite during parasitic infection
Anyone who has weathered a bad stomach bug knows the feeling: a loss of appetite that sets in and lingers, even after the initial illness. For the millions of people around the world who are chronically infected with parasitic ...
Mar 25, 2026
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'RoboGullet' realistically recreates human swallowing by simulating esophagus muscles
University College Dublin researchers have developed a robotic model of the human esophagus, transforming how swallowing disorders are studied, diagnosed and treated. Dysphagia, or difficulty swallowing, affects around 20% ...
Mar 25, 2026
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Meta-analysis of nearly 15,000 people links IBS to low-grade inflammation signs
New research from the University of Newcastle has found that people with irritable bowel syndrome (IBS) show detectable biological changes, challenging the long-held perception that the condition lacks a physical basis. The ...
Mar 25, 2026
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