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Gastroenterology news

Gut-derived bacterial molecule may drive severe liver disease

Researchers at the University of Oslo and Oslo University Hospital, together with international collaborators, have discovered that a small molecule made exclusively by gut bacteria can actively drive disease in the bile ...

C. difficile colonization in infants reshapes gut development, challenging a long-held assumption

Since its discovery, the highly contagious bacterium Clostridioides difficile (C. difficile or C. diff) has been reported not to cause symptoms in infants, leading to the assumption that colonization was not a serious health ...

Are petting zoos safe?

A 3-year-old girl has died from a rare illness after visiting a petting zoo in Victoria. She developed brain damage and kidney failure after spending weeks in intensive care.

Mini-tumors reveal new drug combinations for liver cancer

Liver cancer is difficult to treat because tumors vary greatly from patient to patient. Researchers at the University of Basel have captured this diversity by creating a collection of mini-tumors, which they use to systematically ...

Supplement plus chemotherapy boosts pancreatic cancer survival

When added to standard chemotherapy, a clinical version of the dietary supplement L-glutamine improved survival in an early-phase trial of patients with advanced pancreatic cancer. The study, led by Cedars-Sinai Health Sciences ...

Gut bacterium and its metabolite found to delay aging

A new study published in Nature Aging on Aug. 25 reports that a single gut bacterium—Bifidobacterium pseudocatenulatum (BP)—together with a small molecule it produces, 5-aminovaleric acid betaine (5-AVAB), can alleviate multiple ...

Virtual tumor predicts response to liver cancer immunotherapy

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to predict which patients with a primary liver cancer called hepatocellular ...

Q&A: Rise in cyclosporiasis cases

Cyclosporiasis is a gastrointestinal illness caused by the microscopic parasite Cyclospora. People contract cyclosporiasis by consuming food or water contaminated with feces containing Cyclospora parasites. Health officials ...

KRAS-targeting drugs show promise for rare appendix cancer

Targeting mutant KRAS may offer a promising new treatment option for appendix cancer, according to research from The University of Texas MD Anderson Cancer Center published in the Journal of Hematology & Oncology.