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Genetics news
Oncology & Cancer
Rb1 identified as predictive biomarker for new therapeutic strategy in some breast cancers
A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast ...
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Genetics
Fathers' microplastics exposure tied to their children's metabolic problems
A study led by biomedical scientists at the University of California, Riverside, has shown for the first time that a father's exposure to microplastics (MPs) can trigger metabolic dysfunctions in his offspring. The research, ...
Dec 23, 2025
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New clues to preventing stillbirth: Research highlights premature placental aging
Flinders University researchers have uncovered a biological process that could explain some stillbirths and pave the way for early detection and prevention.
Dec 22, 2025
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First comprehensive Great Steppe genomic dataset uncovers unique variants
Researchers from Nazarbayev University's National Laboratory created the first large-scale, high-quality genotyping dataset of healthy Kazakh individuals—a landmark contribution to global population genomics and biomedical ...
Dec 22, 2025
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Scientists build virtual tissue tools to map how cells talk in disease
Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers study the "conversations" between cells inside the body. The tools, called sCCIgen and QuadST, help ...
Dec 22, 2025
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Genes aren't destiny for inherited blindness, study shows
A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness. Investigators from Mass General Brigham used large public biobanks to determine that genes thought to cause ...
Dec 22, 2025
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Homer1 gene calms the mind and improves attention in mice
Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise. The brain is constantly bombarded with information, and focus depends on its ability to filter out distractions and detect ...
Dec 22, 2025
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BRAF gene mutation leads to different therapeutic responses in melanoma and colorectal cancer
A review article led by researchers from the B·ARGO group at the Germans Trias i Pujol Research Institute (IGTP) and from the Medical Oncology Department of the Catalan Institute of Oncology (ICO) in Badalona provides a ...
Dec 22, 2025
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Major gaps block genetic evaluation and testing for Black and low income patients, study finds
Black patients and patients from socioeconomically disadvantaged neighborhoods are dramatically under-represented in genetics clinics—often at rates half or less than those of white patients or individuals from wealthier ...
Dec 22, 2025
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Improving diagnosis of aortic stenosis with genetics and AI
Aortic stenosis is a narrowing of the aortic valve, which connects the heart to the rest of the body. It affects millions of people and can be fatal if left untreated. At present, there are no effective medical therapies ...
Dec 20, 2025
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Scientists show targeting cancer stem cells can prevent gastric cancer recurrence
Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified the specific cells responsible for gastric cancer's tendency to return after treatment. The study also demonstrated that eliminating ...
Dec 19, 2025
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Cancer's hidden 'safety switch': Silencing TAK1 gene could boost immunotherapy performance
Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.
Dec 19, 2025
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Genomic test helps flag early aggressive prostate cancer in African American patients
A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly ...
Dec 19, 2025
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Is aging an act of genetic sabotage? Scientists find a gene that turns off food detection after reproduction
When roundworms stop reproducing, they can still move and function normally but lose their ability to detect certain food odors that once led them to their meals.
Dec 18, 2025
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Hidden 'switches' in DNA reveal new insights into Alzheimer's disease
A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or so-called 'junk' DNA—includes many of the "switches" that control when and how strongly genes ...
Dec 18, 2025
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Genetic influences on health can ripple through social groups via shared microbes
Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published in Nature Communications.
Dec 18, 2025
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Subtyping colorectal cancer may improve patient outcome predictions
Colorectal cancer, or CRC, is the world's second most lethal cancer based on the number of deaths, and is the third most prevalent malignant tumor. Doctors and patients have long been hoping for better diagnostics for prognosis, ...
Dec 18, 2025
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How disabling one gene protects mice against Type 1 diabetes
Scientists at the University of Wisconsin–Madison have uncovered a possible way to protect key cells in the pancreas that are targeted during the development of Type 1 diabetes.
Dec 17, 2025
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Individual genetic differences can render some antibody-based therapies ineffective
Antibody-based therapies are used to treat numerous diseases, from cancer to rheumatic disorders and multiple sclerosis. Antibodies recognize and bind to very specific structures. This allows them to direct active substances ...
Dec 17, 2025
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New details on role of fat transport molecules in Alzheimer's onset
A new study presents robust evidence on the role of lysophosphatidylcholines (LPCs) in the onset of Alzheimer's disease. Researchers discovered that LPCs—compounds that transport a variety of healthy fatty acids to the ...
Dec 17, 2025
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'Molecular glue' stabilizes protein that inhibits development of non-small cell lung cancer
Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States. Over 80% of lung cancers are non-small cell lung cancers, in which tumor cells are larger and grow more slowly than ...
Dec 17, 2025
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Gene therapy advances as scientists guide jumping DNA to target faulty genes
JABSOM Cell and Molecular Biology researcher Dr. Jesse Owens has spent the better part of two decades chasing a vision that began with the revolutionary idea that DNA can move itself. Now, his team's latest breakthrough is ...
Dec 17, 2025
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Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme's role
Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from IOCB Prague has now described in detail how cells repair this damaged genetic information.
Dec 16, 2025
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Multiple myeloma develops differently in men and women, study reveals
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have uncovered biological differences in how multiple myeloma develops and progresses in men and in women. The rare blood cancer occurs ...
Dec 16, 2025
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Using both genetic information and AI to diagnose pneumonia could curb the overuse of antibiotics
Lung infections like pneumonia are among the world's top killers—but diagnosing them is notoriously hard. Now, researchers at UC San Francisco have found a way to identify these infections in critically ill patients by ...
Dec 16, 2025
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