Last update:
Genetics news
Genetics
A rare respiratory disease may be more prevalent in Quebec
A study led by the Research Institute of the McGill University Health Center (The Institute) has identified a rare genetic variant in the ODAD4 gene that causes primary ciliary dyskinesia (PCD), a chronic hereditary disorder ...
23 hours ago
0
0
Genetics
New insight into how protein TDP-43 affects gene expression in ALS and FTD
Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are medical conditions characterized by the progressive degradation of cells in the brain, ...
Nov 28, 2025
0
30
Why important genes 'go quiet' as we get older
The human gut renews itself faster than any other tissue: every few days, new cells are created from specialized stem cells. However, as we get older, epigenetic changes build up in these stem cells. These are chemical markers ...
Nov 28, 2025
0
57
How a gene shapes the architecture of the human brain
Researchers around the world are studying how the human brain achieves its extraordinary complexity. A team at the Central Institute of Mental Health in Mannheim and the German Primate Center—Leibniz Institute for Primate ...
Nov 28, 2025
0
9
When ribosomes collide, cells launch emergency stress defenses
Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...
Nov 27, 2025
0
0
New mutation hotspot discovered in human genome
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we study genetics and disease.
Nov 26, 2025
0
104
Missing cancer gene explains why some lung tumors respond well to immunotherapy
For some patients with the most common type of lung cancer, known as lung adenocarcinoma, there's new hope. In a new study published in Cell Reports, Mayo Clinic researchers have found several previously unknown genetic and ...
Nov 26, 2025
0
0
Shapeshifting tumors unmasked: New insights into master regulators reveal therapeutic vulnerabilities
Some tumors are almost impossible to treat. That's especially true for carcinomas, which don't behave like other malignancies. Some of these tumors act as shapeshifters and start to resemble cells from other organs of the ...
Nov 25, 2025
0
50
Research challenges idea that gene PTPN22 boosts production of interferons
A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide influences production of type 1 interferon, a workhorse of the immune system. The work is published in ...
Nov 25, 2025
0
0
Deep learning model has identified imaging biomarker for chronic stress
A deep learning model has identified an imaging biomarker of chronic stress, according to a study to be presented at the annual meeting of the Radiological Society of North America, being held from Nov. 30 to Dec. 4 in Chicago.
Nov 25, 2025
0
0
Novel discovery reveals how brain protein OTULIN controls tau expression and could transform Alzheimer's treatment
Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease. The findings, published in Genomic Psychiatry, ...
Nov 25, 2025
0
15
MRIs reveal genetic clues in cerebral palsy
A national study by University of Adelaide researchers is paving the way for more precise diagnosis and treatment for children with cerebral palsy.
Nov 25, 2025
0
0
Genetic study links impulsive decision making to a wide range of health and psychiatric risks
Researchers from University of California San Diego have identified 11 genetic regions linked to delay discounting—the tendency to prefer smaller, immediate rewards over larger, delayed ones—shedding new light on how ...
Nov 24, 2025
0
27
Rare mutation protects brain's immune cells from Alzheimer's disease
Rutgers neuroscientist Peng Jiang and his neuroscience colleague Mengmeng Jin have made a discovery they say could reshape how scientists think about Alzheimer's treatment.
Nov 24, 2025
0
61
AI learns from the tree of life to support rare disease diagnosis
Researchers have created an artificial intelligence model that can identify which mutations in human proteins are most likely to cause disease, even when those mutations have never been seen before in any person.
Nov 24, 2025
0
119
APOE gene raises delirium risk even without dementia, global analysis reveals
A major genetic risk factor for delirium has been identified in a study that analyzed the DNA of more than 1 million people worldwide.
Nov 24, 2025
0
23
Researchers highlight genetic factors in pediatric brain and spinal cord tumors
Researchers at Children's Hospital of Philadelphia (CHOP) and Children's National Hospital in Washington D.C. are uncovering how rare inherited genetic variants contribute to the development of brain and spinal cord tumors ...
Nov 24, 2025
0
2
Cellular targets to overcome KRAS inhibitor resistance in pancreatic tumors identified
A study led by University of Cincinnati Cancer Center researchers sheds new light on how pancreatic cancer cells resist treatment and points to potential new combination therapies to make treatments more effective.
Nov 24, 2025
0
0
Genetic mechanisms promote antimicrobial resistance in gonorrhea
Northwestern Medicine scientists have identified previously unknown genetic mechanisms that promote antimicrobial resistance in gonorrhea, findings that may inform the development of more effective treatment strategies, according ...
Nov 24, 2025
0
0
Epigenetic changes regulate gene expression, but what regulates epigenetics?
All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in each cell. Mistakes or ...
Nov 23, 2025
0
79
Many who die by suicide aren't depressed, genetic research suggests
Among friends and family of those who die by suicide, a common refrain is: I didn't know. While some people who die by suicide have prior attempts, about half of people who die by suicide have no documented suicidal thoughts ...
Nov 21, 2025
1
51
Genetic events that can trigger leukemia in patients with a rare disorder deciphered
Two parallel and complementary studies conducted by the IDIBELL team led by Dr. Alessandra Giorgetti have succeeded in recreating models of GATA2 deficiency disease, a rare genetic disorder that affects fewer than 1 million ...
Nov 21, 2025
0
18
Genetic risk combined with cardiovascular factors may help predict and delay dementia
Combining genetic risk with cardiovascular disease risk factors—such as high LDL cholesterol, obesity, and hypertension—may predict who is more likely to develop dementia, according to a new study led by UC San Francisco.
Nov 21, 2025
0
0
Study uncovers and predicts widespread molecular changes in ALS brain cells
Researchers at the University of Toronto's Temerty Faculty of Medicine have found widespread genetic and protein changes in the brain cells of people with amyotrophic lateral sclerosis (ALS), which may help shed light on ...
Nov 21, 2025
0
0
How a consortium is advancing the diagnostics of rare diseases
The National Institutes of Health established the Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium in 2021 with the goal of finding molecular diagnoses for individuals with rare diseases who ...
Nov 21, 2025
0
0
