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Clinical genetics news
Precision RNA therapy offers hope for brain receptor disorders
Scientists at Johns Hopkins University School of Medicine and Academia Sinica in Taiwan have developed an experimental RNA-based treatment that prevents brain damage and improves learning, memory and social behavior in mice ...
8 minutes ago
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New test identifies people at higher risk of glaucoma, the leading cause of irreversible blindness
A new genetic test developed by researchers at QIMR Berghofer and Flinders University, along with international collaborators, can identify people at up to 10 times the normal risk of developing open-angle glaucoma, the most ...
6 hours ago
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Rare genetic discovery explains sex development differences in two XY sisters
Two young girls in Vietnam are living proof that there is a lot more to sex than genetics, after being found to have an extremely rare sexual development condition.
22 hours ago
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First complete genomes for neglected malaria parasites revealed
Scientists have produced gold-standard reference genomes for previously neglected malaria parasites by sequencing low-input DNA directly from patient blood, bypassing lab culture.
22 hours ago
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Broad genomic testing linked to longer survival in advanced lung cancer, according to new study
New research in the November 2026 issue of Journal of the National Comprehensive Cancer Network found that patients with advanced non-small cell lung cancer (NSCLC) lived longer when they received broad-based genomic sequencing ...
14 hours ago
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Human basal ganglia atlas reveals how genes are regulated in individual cells
Salk Institute researchers have contributed to a landmark accomplishment in neuroscience: a 3D atlas of the human basal ganglia with single-cell genetic and epigenetic detail, published as a collection of 28 papers across ...
Nov 12, 2026
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Christchurch mutation points to potential gene therapy avenue for Parkinson's
A rare genetic mutation may protect against developing Parkinson's disease and Lewy body dementia, a new study from researchers at Oregon Health & Science University suggests.
Nov 11, 2026
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Could your genes affect your medications? New study highlights high probability
Everyone in a diverse, nearly 100,000-person sample carried at least one genetic variant that affects how their body processes medications, and a quarter of those people had been prescribed a medication that is known to be ...
Nov 11, 2026
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Patient age may shape which mutations drive melanoma
Precision medicine for cancer seeks to match treatment to the genetic changes found in a patient's tumor. A new Yale study suggests that for melanoma there may be an important clue to consider: the patient's age.
Nov 11, 2026
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Testing BRCA1 variants reveals differences in breast cancer risk
Researchers at the Francis Crick Institute have tested thousands of possible BRCA1 mutations in mammary gland cells to shed light on which genetic variants confer a high risk of developing breast cancer. Research like this ...
Nov 11, 2026
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New 'FITdb' database reveals the genetic drivers of immune cell function
Scientists at La Jolla Institute for Immunology (LJI) have developed a critical hub for functional genomics and immune cell research. LJI Assistant Professor Miguel Reina-Campos directs the new Functional Immunogenomics and ...
Nov 11, 2026
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Science solves genetic mystery behind fatal brain disorder in babies and children
Researchers at King Abdullah University of Science and Technology (KAUST) and King Faisal Specialist Hospital and Research Center (KFSHRC) identify a previously unknown cause of a fatal newborn brain disorder, giving long-awaited ...
Nov 11, 2026
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Axonal defects linked to rare form of Parkinson's disease
A genetic mutation linked to Parkinson's disease produced abnormalities in a subset of nerve cells, offering a clue about the disease's causes, according to a new study published in the Proceedings of the National Academy ...
Nov 10, 2026
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Alzheimer's discovery reveals brain cleaning gone wrong
A gene responsible for compacting trash inside the brain appears to be a key player in Alzheimer's disease, and doctors may be able to target it to better treat or help prevent the devastating condition, new UVA Health research ...
Nov 10, 2026
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Study finds that genetic risk does not explain the maternal effect in type 1 diabetes
Children whose mothers have type 1 diabetes develop the disease at about half the rate of children whose fathers have it. Inherited genetic risk alone does not explain this long-observed maternal effect, according to a study ...
Nov 10, 2026
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Researchers identify DNA marker that could predict treatment response in myelodysplastic syndromes
DNA methylation patterns present at diagnosis could help predict which patients with myelodysplastic syndromes (MDS) will respond to azacitidine. That's the key finding of a new multicenter study involving researchers at ...
Nov 10, 2026
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Genetic variant among Black people linked to hardening of arteries, Alzheimer's disease
Rutgers-Newark researchers have discovered that a genetic variant unique to people of African descent heightens the link between so-called "hardening of the arteries" and Alzheimer's disease.
Nov 10, 2026
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What are biomarkers? How doctors assess health and pooling people's cells reveals new markers—a biologist explains
A family of five is exposed to the flu virus, but only two of them get sick. A lifelong chain-smoker lives 100 years, while a professional athlete in their prime dies of an unexpected heart attack. A drug fails a clinical ...
Nov 10, 2026
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Scientists turn protein-making errors in cancer cells into a targeted kill switch
Like every other cell in the human body, cancer cells also produce their own share of proteins for survival. During this production process, cells often encounter a glitch called ribosomal frameshifting. This exceptionally ...
DNA 'switch' uncovers new brake on breast cancer growth
Adelaide University researchers have found a DNA "switch" that helps the body stop the growth of the most common form of breast cancer, providing new insights that could help with future treatments. Up to 80% of breast cancer ...
Nov 6, 2026
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Drug restores kidney cell function in experimental models of rare Lowe syndrome
Over two decades of research into the cellular mechanisms underlying Lowe syndrome have led to the identification of a potential therapeutic strategy for this rare genetic disorder, which affects the eyes, nervous system ...
Nov 6, 2026
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New research identifies biological differences in pancreatic cancer
New research from the University of Cincinnati Cancer Center found biological differences in pancreatic cancer tumors and immune environments, opening the possibility for more personalized treatments for different populations.
Nov 6, 2026
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Genetic variant may increase the risk of pneumonia
Pneumonia is a common and sometimes serious infection that affects 20,000–30,000 people in Sweden every year. Well-known risk factors include advanced age, smoking and underlying medical conditions. In a new study published ...
Nov 6, 2026
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Researchers establish best methods to measure genetic variation within the body
WashU Medicine researchers have verified the accuracy of genetics tools to correctly identify all the rare DNA changes that make up an individual's genomic mosaic, paving the way to understanding these variants' impact on ...
Nov 5, 2026
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Neural signaling protein could be therapeutic target for autism-linked gene deletion
A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in ...
Nov 5, 2026
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