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Clinical genetics news

How specific changes in DNA shape human brain structure

Why do human brains vary in size and shape, and how did our brains expand over evolutionary time to give us our enhanced cognitive abilities? Researchers at the UNC Department of Genetics and the UNC Neuroscience Center have ...

How the APOE4 gene damages brain blood vessels in Alzheimer's disease

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease. ...

Genetic clues help reveal kids' cancer risk

Every person is a collection of genetic puzzle pieces. On their own, those pieces can be hard to understand, but together, they form the picture that is you.

New gene discovery could help identify better stem cell donors

Research from stem cell charity Anthony Nolan, published in Transplantation and Cellular Therapy, has revealed that 1 in 50 people studied has an "especially useful" gene variant that could make them a particularly desirable ...

Big data analysis sheds light on psoriasis's genetic code

A research team from South Korea has revealed the specific mechanisms behind the onset of psoriasis by combining large-scale genomic data from more than 1.1 million people with advanced single-cell analysis technology. The ...