Spouses mattered more than genes for the risk of severe COVID-19
Why did some people become severely ill with COVID-19 while others experienced only mild symptoms? Associate professor Maria Timofeeva and assistant professor Jacob Krabbe Pedersen from the Department of Public Health at ...
9 hours ago
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Repeating stretch of DNA offers a new clue to Alzheimer's susceptibility
A three-letter sequence repeating along a stretch of DNA could offer new clues about why some people are more susceptible to Alzheimer's disease than others. The sequence, CCG, sits in a region of DNA that controls the gene ...
New CRISPR approach targets gene fusions found in 1 in 5 cancers
Peter Mac scientists have developed a way to precisely target the "unique molecular fingerprint" created when two genes become abnormally fused together, a discovery that could lead to a new way to treat a wide array of cancers.
Oct 19, 2026
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Advanced paternal age has sex-specific effects on fetal brain gene expression, mouse study suggests
When genes are "expressed," it is like reading an instruction manual to create things the body needs—such as proteins or RNA. It is an important process in regulating normal cellular functions. Understanding more about gene ...
Oct 19, 2026
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Fast-tracked genetic testing helping sick kids
A new genetic testing approach for sick children with immune conditions could slash diagnosis waiting times from 12 months to as little as two weeks, University of Queensland research has found.
Oct 19, 2026
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DNA sequencing reveals how rare cancer spread between twins before birth
Two identical sisters came into the world carrying the same rare cancer. They lost their lives to an undifferentiated sarcoma, a soft-tissue cancer driven by a unique gene fusion (MN1::ZNF341). The story began before they ...
Genomic cancer driver study reveals new clues to why some prostate cancers become aggressive
Why do some prostate cancers grow slowly for years, while others progress quickly to life-threatening metastatic disease? An international team of researchers co-led by the Ontario Institute for Cancer Research (OICR) and ...
Oct 16, 2026
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Researchers develop new AI tool to better predict stroke risk
Researchers from the University of Technology Sydney (UTS) have developed an AI model that analyzes a person's DNA to better identify genetic risk factors for stroke, paving the way for more personalized risk assessments.
Oct 16, 2026
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AI tool helps identify harmful epilepsy genetic variants
A new artificial intelligence tool developed by Northwestern Medicine scientists and collaborating institutions can help determine whether genetic variants associated with a severe form of childhood epilepsy will cause disease, ...
Oct 15, 2026
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Reversing age by reprogramming gene expression networks
Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified "hallmarks of aging" that not only present specific processes impacted by age, but are also thought of as ...
Oct 14, 2026
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What happens when brain tumors return? International study tracks genetic changes behind recurring cancers
When patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns. Among those are IDH-mutant gliomas, a group of brain tumors that invariably recur despite ...
Oct 14, 2026
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Reversible genetic switches could give cancer immunotherapy more precise control
A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute ...
Oct 14, 2026
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Trapping cancer-driving DNA rings outside cell nucleus silences their genes, researchers find
Cells from rapidly growing, highly metastatic tumors often contain numerous rings of extrachromosomal DNA (ecDNA). This circular DNA frequently carries oncogenes—genes that promote cancer. Researchers have long sought vulnerabilities ...
Oct 14, 2026
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Overlooked DNA regions surrounding 'microexons' may hold missing pieces of autism's genetic puzzle
New research from scientists at the University of Toronto, the Sloan Kettering Institute, King's College London (KCL) and the Francis Crick Institute is helping piece together the missing genetics of autism spectrum disorder ...
Oct 14, 2026
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Researchers identify role of newly discovered genetic variant in neurodevelopmental disorder
Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the mechanisms of previously unknown changes in a gene that result in symptoms associated with a neurodevelopmental disorder. The findings underscore ...
Oct 14, 2026
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A drug can make children with the most common form of dwarfism taller—but height isn't the same as a better life
A drug that helps children with the most common form of dwarfism grow taller has sparked an ethical debate within the dwarfism community.
Oct 14, 2026
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Continuously evolving cells help pancreatic cancer evade treatment and spread
An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment for one of the deadliest forms of cancer.
Oct 13, 2026
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Prime editing repairs immune disorder defect in patient's own blood stem cells
Some people are born with a defect in their genetic material that prevents their immune system from functioning properly. In people with a condition known as GATA2 deficiency, the body does not produce enough immune cells, ...
Oct 13, 2026
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Bigger data reveal the second, third and fourth switches controlling a gene
We now take for granted the idea that a genome-wide association study, or GWAS, can help identify genetic variants associated with complex traits. Such studies have identified loci associated with everything from breast cancer ...
Oct 13, 2026
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Helping others linked to slower cognitive decline among people at higher genetic risk for Alzheimer's
Regularly volunteering or informally helping people outside one's home may buffer against accelerated decline in memory and thinking for people with a major genetic risk factor for Alzheimer's disease, according to new research ...
Oct 13, 2026
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Had genetic testing for cancer risk years ago? Newer tests may find what old ones missed
Women who had genetic testing for inherited cancer risk years ago may want to ask about testing again, experts say.
Oct 13, 2026
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Experiments reveal how DNA-packaging protein mutation promotes breast cancer spread
A research team led by professor Chan Kui-ming from the Department of Biomedical Sciences at CityUHK discovered that H2BE113K, a missense H2B mutation, promotes colony formation and lung metastasis in breast cancer. The research ...
Oct 12, 2026
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Study offers new clues about how genetic risk for Alzheimer's affects brain immune cells
Researchers at the University of Colorado Anschutz and Pacific Northwest National Laboratory have found a new clue that may help explain why some people are more likely to develop Alzheimer's disease. It suggests that a protein ...
Oct 12, 2026
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