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Genetics news
Genetics
Single prime editing system could potentially treat multiple genetic diseases
A team of researchers at the Broad Institute, led by gene-editing pioneer David Liu, has developed a new genome-editing strategy that could potentially lead to a one-time treatment for multiple unrelated genetic diseases.
5 hours ago
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Genetics
Uncovering the hidden cellular connections that bridge aging and disease
A Yale research team has created a new imaging technique that reveals the hidden connections between aging, disease, and genetic activity in human cells.
9 hours ago
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Genomic analysis tool aids Scotland's fight against antibiotic-resistant infections
Bacterial infections can spread quickly, especially in hospital settings or crowded communities, where vulnerable people are treated in close proximity and bacteria move between them. Antimicrobial-resistant infections are ...
1 hour ago
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Most people with a genetic condition that causes significantly high cholesterol go undiagnosed, study finds
Current genetic screening guidelines fail to identify most people with an inherited condition known as familial hypercholesterolemia that can cause dangerously high cholesterol and early heart disease, a Mayo Clinic study ...
16 hours ago
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Rare genetic variants can increase ADHD risk by up to 15 times
ADHD is a neurodevelopmental disorder with a high heritability, in which the genetic component consists of thousands of genetic variants. Most variants only slightly increase the likelihood of receiving the diagnosis. Now ...
Nov 18, 2025
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Chronic lymphocytic leukemia: New origins and biomarkers revealed
Researchers at the University of Eastern Finland and their international collaborators have identified key developmental and molecular differences between the two main subtypes of chronic lymphocytic leukemia, CLL. The findings, ...
Nov 18, 2025
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RNA therapy silences KRAS gene and boosts immune attack on cancer cells
Two complementary studies led by researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have demonstrated a new RNA-based therapeutic strategy that effectively targets one of ...
Nov 18, 2025
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Gene 'switch' reverses Alzheimer's risk in experimental model
University of Kentucky researchers have developed a new experimental model that could point the way toward more effective Alzheimer's disease treatments by targeting one of the brain's most important genes for risk and resilience.
Nov 17, 2025
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CRISPR breakthrough reverses chemotherapy resistance in lung cancer
In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach ...
Nov 17, 2025
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Fertility treatments linked to higher mutations than natural conception in mice
Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive technologies suggests.
Nov 17, 2025
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DNA methylation patterns in newborns point to susceptibility to schizophrenia
Genetic susceptibility to neurodevelopmental conditions such as schizophrenia, autism, and ADHD can be linked, in part, to distinct epigenetic signatures in newborn cord blood. An analysis of nearly 6,000 newborns published ...
Nov 17, 2025
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New potential gene-based treatment for sepsis and lung injury
A new discovery from the lab of YouYang Zhao, Ph.D., from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, opens promising new directions for treatment of life-threatening ...
Nov 17, 2025
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Molecule that could cause COVID clotting key to new treatments
In a surprising discovery, a "sticky molecule" that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new treatments to counter COVID-related ...
Nov 17, 2025
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Dutch hospital pioneers new genetic test in clinical practice
Radboudumc is the first hospital in the world to use a new genetic test on a large scale in clinical practice. This test provides more people with a diagnosis for rare conditions and is faster and more efficient than current ...
Nov 17, 2025
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A time-sensitive genetic switch for sex-specific features of developing neurons
Researchers have identified that the precisely timed transcription of two genes named grim and reaper is responsible for the targeted death of neurons within the developing nervous system of female flies. This group of neurons ...
Nov 16, 2025
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New genetic test targets elusive cause of rare movement disorder
Scientists at Brigham and Women's Hospital and Harvard Medical School have developed a targeted genetic test to improve diagnosis for X-linked dystonia-parkinsonism (XDP), a rare and disabling movement disorder that affects ...
Nov 15, 2025
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Changes in a single gene can cause mental illness, study reveals
Until now, researchers assumed that schizophrenia, anxiety disorders or depression arise from an interplay of many different factors, including genetic ones.
Nov 14, 2025
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Q&A: Identifying new risk genes for schizophrenia
Schizophrenia, a psychiatric disorder that affects how a person feels, thinks, and behaves, affects roughly 1% of the population (approximately 3.5 million people in the U.S.) and is a leading cause of disability and death. ...
Nov 14, 2025
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Overlooked layer of DNA may explain disease risk, severity
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that could help explain why people experience disease differently, and why some treatments work better ...
Nov 14, 2025
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Researchers to test gene therapy for rare diseases with a new FDA trial protocol
Earlier this year, researchers at Children's Hospital of Philadelphia and Penn created a first-of-its-kind drug customized to a unique genetic mutation to save an infant named Baby KJ from dying of a rare liver disorder.
Nov 14, 2025
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Genetic tool reveals chromosome changes linked to pregnancy loss
Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about half are caused by genetic or chromosomal issues.
Nov 14, 2025
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Researchers reveal intricate control system for key immune gene
The immune system faces a delicate balancing act: It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.
Nov 13, 2025
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Genes may predict suicide risk in depression
Depression in young adulthood has a stronger hereditary component and is associated with a higher risk of suicide attempts than depression that begins later in life, according to a new study published in Nature Genetics by ...
Nov 13, 2025
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New gene discoveries improve diagnosis of inherited heart disease
Centenary Institute researchers have uncovered new genetic causes of inherited heart conditions, providing families with vital answers to guide treatment and prevention.
Nov 13, 2025
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Nature vs. nurture: Sequencing study quantifies genetic influence on human traits and diseases
Genome sequencing has been used to determine how much genes influence human characteristics including height and weight, and susceptibility to diseases like type 2 diabetes, in a study co-led by University of Queensland researchers ...
Nov 12, 2025
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