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Genetics news
Genetics
Genetic test predicts response to weight-loss drugs
Mayo Clinic researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.
4 hours ago
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Genetics
Late-life virginity: Mapping genetic, psychological and social factors in adults who have never had sex
Researchers from Karolinska Institutet, the Max Planck Institute for Empirical Aesthetics (Germany), Amsterdam UMC (Netherlands), in collaboration with other international partners, have conducted the most extensive study ...
20 hours ago
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CRISPR approach offers hope for severe childhood brain disorder
When brain development gets off to a bad start, the consequences are lifelong. One example is a condition called SCN2A haploinsufficiency, in which children are born with just one functioning copy of the SCN2A gene—instead ...
22 hours ago
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Reprogramming the epigenetic code affects growth and survival of tumor cells in multiple myeloma
In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of chemical "tags" on DNA and proteins that control whether genes are turned on or off. These "tags" affect ...
18 hours ago
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Gene editing may represent a new way to treat inherited kidney disease
Researchers in Berlin have used base editing to repair mutations that cause the kidney disorder ADPKD in cells from both mice and humans. In mice, a team led by Michael Kaminski was able to ease a key symptom of the difficult-to-treat ...
18 hours ago
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Study identifies genetic loci that link brain structure and various psychiatric disorders
The development of many psychiatric disorders, including depression, schizophrenia and bipolar disorder, is known to be in great part influenced by genetics. Past research has identified various genes that appear to be associated ...
AI-powered CRISPR could lead to faster gene therapies
Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments. The technology, CRISPR-GPT, acts as a gene-editing "copilot" supported by AI to help researchers—even ...
Sep 16, 2025
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Uncovering drivers of—and possible treatment for—Noonan syndrome heart defects
Noonan syndrome with multiple lentigines (NSML) is a rare genetic disorder that causes short stature, distinctive facial features, and clusters of dark skin spots called lentigines. But its most serious impact is a dangerous ...
Sep 16, 2025
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How HIV enters the genome—study decodes previously unknown mechanism
Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome. A research team ...
Sep 15, 2025
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Genetic variants may explain why obesity affects people differently
An international team of researchers led by Icahn School of Medicine at Mount Sinai and the University of Copenhagen in Denmark has pinpointed some of the reasons why obesity does not affect everyone in the same way. Their ...
Sep 15, 2025
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Research links DNA replication failure to cancer therapy
A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals from RB tumor suppressor ...
Sep 15, 2025
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Finding patterns in genetic uncertainty: Clues for inborn errors of immunity
Behind every unexplained medical condition is a patient hoping for clarity and understanding. For people with suspected inborn errors of immunity (IEIs), genetic testing can facilitate individually tailored and effective ...
Sep 15, 2025
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Gene therapy safeguards hearing, balance in preclinical test
Scientists from the Gray Faculty of Medical & Health Sciences at Tel Aviv University introduced an innovative gene therapy method to treat impairments in hearing and balance caused by inner ear dysfunction. According to the ...
Sep 15, 2025
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Researchers work to make blood cancer a manageable illness with mutation identification
As blood cancers are constantly evolving and developing mutations that grow resistance to current treatments, researchers in the University of Cincinnati Cancer Center's Leukemia and Drug Development Lab (LDDL) are constantly ...
Sep 15, 2025
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Genetic deletion in cerebellum impedes hemisphere formation, study finds
The cerebellum, a brain region located at the back of the head that has long been known to support the coordination of muscle movements, has recently also been implicated in more sophisticated mental functions. Purkinje cells ...
The 'aldehyde storm': How a gene mutation found in East Asian people increases liver disease risk
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce ...
Sep 12, 2025
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Cannabis use may harm reproductive health and reduce healthy embryos in IVF
CReATe Fertility Center in Toronto reports that tetrahydrocannabinol (THC) reaches the ovarian follicle, aligns with higher oocyte maturation, and associates with lower embryo euploid rates in IVF, with in vitro exposure ...
Customized gene-editing technology shows potential to treat lethal pediatric disease
Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood. Currently, there is no effective treatment or cure for MSMDS.
Sep 11, 2025
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Cell defect in exosomes linked to development of Alzheimer's
They're tiny particles—with potentially huge human consequences. Researchers from Aarhus University have identified a defect in the production of so-called exosomes in cells, associated with a mutation seen in dementia ...
Sep 11, 2025
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Genetic peptides that shape gut bacteria may protect against obesity and diabetes
New research from the University of Sydney's Charles Perkins Center has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea that gut health is influenced only by diet.
Sep 11, 2025
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Surprising new roles discovered for known blood cancer gene DNMT3A
A gene called DNMT3A is important for guiding blood stem cells into forming all the cell types present in blood, including red blood cells, white blood cells and platelets. When this gene accumulates mutations—which might ...
Sep 11, 2025
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Multi-disciplinary approach sheds light on the role of mitochondrial DNA mutations in cancer
Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might affect cancer growth.
Sep 11, 2025
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New treatments found for tough blood cancers
Researchers from King's have identified a new way to treat certain blood cancers using existing drugs, by turning a once-dismissed part of our DNA into a therapeutic target.
Sep 11, 2025
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Breaking the code of sperm motion: Two proteins found vital for male fertility
There are many potential causes of infertility, and it can be challenging to pin down just what the problem is when a couple is having trouble getting pregnant. Now, researchers show that a few key proteins have a major effect ...
Sep 10, 2025
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Microplastic exposure linked to Alzheimer's disease in mice with APOE4 gene
Micro- and nanoplastics prevalent in the environment routinely enter the human body through the water we drink, foods we eat, and even the air we breathe. Those plastic particles infiltrate all systems of the body, including ...
Sep 10, 2025
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