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HIV & AIDS news

HIV & AIDS

Early HIV drugs give immune system a brief reprieve before dysregulation returns, study finds

Despite effective HIV medication, the immune system of people with HIV remains disrupted in the long term.

HIV & AIDS

Low-dose THC may reduce side effects of HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

HIV & AIDS

Early HIV treatment: Research reveals critical gaps

In an article published in The Lancet HIV, authors including Distinguished Professor Denis Nash and Professor Constantin Yiannoutsos aim to provide the most comprehensive estimates of pediatric mortality among children and ...

HIV & AIDS

How HIV disrupts sleep across Africa

HIV significantly affects sleep, with many affected people living in a state akin to chronic jet lag. A new study with Wits researchers published in The Lancet HIV describes how people living with HIV (PLWHIV) experience ...

HIV & AIDS

Study reveals accelerated aging in women living with HIV

Women with HIV experience accelerated DNA aging, a phenomenon that can lead to poor physical function, according to a study led by Stephanie Shiau, an assistant professor in the Department of Biostatistics and Epidemiology ...

HIV & AIDS

New research advances potential HIV cure strategy

Published in the Journal of Infectious Diseases, new research led by the University of Minnesota Medical School offers a new avenue of hope in the fight against chronic human immunodeficiency virus (HIV) infection.

Medications

How a novel drug pushes the HIV capsid to breaking point

Just over a year ago, the European Union and the US Food and Drug Administration approved a new anti-retroviral drug to treat human immunodeficiency virus (HIV) infections. Lenacapavir is the first drug available to patients ...

Medical research

Researcher explores sex-specific features of HIV

Early in her career, Johns Hopkins physician-scientist Eileen Scully began to explore ways that viral infections such as HIV, SARS-CoV-2 and tuberculosis manifest differently in individuals. One particular interest: The differences ...

HIV & AIDS

Scientists see an ultra-fast movement on surface of HIV virus

As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.

HIV & AIDS

Researchers pinpoint most likely source of HIV rebound infection

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify ...

Medical research

How does HIV get into the cell's center to kickstart infection?

UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.

Medical research

HIV: Early treatment is one key to remission

People living with HIV need to take antiretroviral treatment for life to prevent the virus from multiplying in their body. But some people, known as "post-treatment controllers," have been able to discontinue their treatment ...

HIV & AIDS

HIV antibodies protect animals in proof-of-concept study

Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people. The ...

HIV & AIDS

Researchers identify novel factor in HIV transmission

University of Virginia School of Medicine researchers have found long-sought answers to questions about HIV transmission, and those findings could lead to new ways to prevent the disease's spread.

HIV & AIDS

Unlocking the mechanisms of HIV in preclinical research

Mayo Clinic researchers have unraveled the molecular mechanisms that affect which cells infected with human immunodeficiency virus (HIV) die and which survive, a discovery heralded as a step toward eliminating all HIV-infected ...

HIV & AIDS

Higher viral load during HIV infection can shape viral evolution

A new paper in Molecular Biology and Evolution finds that HIV populations in people with higher viral loads also have higher rates of viral recombination. In effect, the more HIV in the blood, the easier it is for the virus ...