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Immunology news
Oncology & Cancer
Q&A: Combination therapy shows promise for overcoming treatment resistance in glioblastoma
Rakesh Jain, Ph.D., director of the Edwin Steele Laboratories for Tumor Biology in the Department of Radiation Oncology at Massachusetts General Hospital and Andrew Werk Professor of Radiation Oncology at Harvard Medical ...
3 hours ago
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Medications
Vitamin D3 concentrations are lowered by a common vitamin D supplement
Taking vitamin D2 might lower the body's levels of the more efficient form of vitamin D, vitamin D3, according to new research from the University of Surrey, John Innes Center and Quadram Institute Bioscience. Many people ...
8 hours ago
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Lymph nodes found to be key to successful cancer immunotherapy
A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against ...
Sep 17, 2025
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Investigating how tumor-immune cell clusters drive breast cancer spread
In a pair of studies, investigators from the lab of Huiping Liu, MD, Ph.D., associate professor of Pharmacology and of Medicine in the Division of Hematology and Oncology, have uncovered how specific cellular interactions ...
Sep 17, 2025
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COVID-19 vaccine responses show four patterns, with 'rapid-decliners' at higher infection risk
Two health care workers get COVID-19 vaccinations on the same day. Both show strong antibody responses initially, but six months later one stays healthy while the other contracts the virus. A new study published in Science ...
Sep 17, 2025
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Stronger together: A new fusion protein boosts cancer immunotherapy
A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein ...
Sep 17, 2025
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Subtle cues between cells and immune system can contribute to spread of cancer
In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new colonies within the body. Blocking the cells' ability to follow the trail might halt metastasis but ...
Sep 17, 2025
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Skin stretching enables needle-free vaccine delivery in mice
Researchers show that stretching the skin stimulates immune cells and increases the skin's ability to absorb large molecules, including those present in vaccines. In an article published September 17 in Cell Reports, they ...
Sep 17, 2025
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'Molecular glue' harnesses the power of the immune system to treat neuroblastoma
Gene expression governs whether neuroblastoma tumor cells exist in either the adrenergic (differentiated and sensitive to treatment) or mesenchymal (less differentiated and therapy-resistant) cell state. Tumors may switch ...
Sep 17, 2025
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Scientists discover proteins that initiate cellular immunity in bone marrow
A researcher at the Hackensack Meridian Center for Discovery and Innovation (CDI) and physician-scientist colleagues from Hackensack Meridian Health have shown how a critical pathway is fundamental to the immune system.
Sep 17, 2025
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Lactate-driven protein modification weakens natural killer cell cancer defenses
A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in collaboration with Prof. Ding Chen's team from Human Phenome Institute at Fudan University, has elucidated ...
Sep 17, 2025
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NONO molecules block immune system defenses against breast cancer, so researchers switched it off
A new study has identified a potential new target for treating triple-negative breast cancer, one of the most aggressive forms of breast cancer, which still has very few therapeutic options available. The study was carried ...
Sep 17, 2025
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New data sheds light on immunotherapy failure, bringing hope to patients with cancer
A new study by researchers from the University of Birmingham and the University of Turku, Finland has revealed an important clue as to why immunotherapy fails in many patients with cancer.
Sep 17, 2025
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Your immune system attacks drugs like it does viruses, paradoxically offering a way to improve cancer treatment
When the first cells appeared on Earth approximately 3.8 billion years ago, viruses were already here to greet them. Ever since, viruses have been devising ways to infect cells, and cells have been responding by evolving ...
Sep 17, 2025
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IL-10 is a small protein with a big part in preventing pulmonary fibrosis
For a long time, physicians and scientists believed our lungs were sterile (germ-free). But modern science indicates otherwise. Now we know they contain allergens, bacteria or viruses we inhale, such as influenza or SARS-COV-2, ...
Sep 16, 2025
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Pain-detecting nerve cells could yield new way to manage lung scarring
Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found that neurons known to help detect pain are also critical for reducing harmful lung inflammation that leads to the ...
Sep 16, 2025
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Two-part prodrug system activates immune attack only in tumor's unique environment
Scientists have developed a smarter way to activate the immune system against cancer, potentially making treatments safer and more precise.
Sep 16, 2025
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The 'Catch-22' of aging: Our immune system protects us by committing our cells to die
Some of our biggest threats can come in the tiniest forms—viruses and bacteria. Thankfully, we are born with a built-in defense system, our innate immune system that protects us in our youth but can turn against us as we ...
Sep 16, 2025
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Promising drug combinations for immunotherapy-resistant melanoma may also help reactivate immune system
Researchers at Sutter's California Pacific Medical Center (CPMC) in San Francisco, Calif. have identified potential new therapeutic strategies for patients with advanced melanoma who no longer respond to immunotherapy—an ...
Sep 16, 2025
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Lymph node study reveals how aggressive breast cancer evades immune detection
In almost all solid tumors—i.e. cancers with a solid tissue structure—the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease. Lymph node involvement has a significant ...
Sep 16, 2025
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Kidney transplant rejection associated with changes in lymphatic vessels, new research shows
Scientists have uncovered how lymphatic vessels—the kidney's "plumbing system"—undergo dramatic changes during chronic transplant rejection, becoming structurally disorganized and spreading to unusual parts of the kidney.
Sep 16, 2025
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Study finds experimental antibody may reduce fibrosis in chronic kidney disease
Chronic kidney disease is a growing health concern affecting about 1 in 10 Swedes. The condition involves a gradual decline in kidney function, which can lead to the need for dialysis or transplantation.
Sep 16, 2025
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Biomarkers linked to side effects from cancer immunotherapy
A team led by UT Southwestern Medical Center scientists has identified early signals from the immune system that could help predict which cancer patients are most likely to develop harmful side effects from immunotherapy. ...
Sep 16, 2025
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Study shows change in diet could reduce lymphedema
When Spencer Gibson arrived at the University of Alberta four years ago to assume his new role as the Dianne and Irving Kipnes Endowed Chair in Lymphatic Disorders in the Faculty of Medicine & Dentistry, he knew the task ...
Sep 16, 2025
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Breaking down the layers of the immune system: Advice from an immunologist
It starts with a sneeze. Someone on the subway didn't cover their mouth and now a cloud of invisible invaders hangs in the air. Before you even step off the train, your immune system has already begun fighting off the threat ...
Sep 16, 2025
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