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Allergy and immunology news
A renewable cell source for cancer immunotherapy could make off-the-shelf treatments possible
In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of the progenitor cells that give rise to macrophages. These immune cells help drive the body's response ...
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Lab-on-a-chip platform shows how immune cells attack cancer cells
Immunotherapies are a promising approach in the fight against cancer. Researchers at the Technical University of Munich (TUM) have developed a lab-on-a-chip system called CellTrap. It makes it possible to observe the interactions ...
19 hours ago
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A diet-derived nutrient in breast milk may shape immune development
Trans-vaccenic acid (TVA), the most abundant trans fatty acid found in human breast milk, helps boost immune system development and has long-lasting effects on immune system health in mice, according to a new study by researchers ...
19 hours ago
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SARS and MERS trigger immune brake that shuts down antiviral defenses, study finds
Researchers from Trinity have discovered how two deadly coronaviruses (SARS1 and MERS) outsmart one of our most important antiviral defenses by shutting down parts of the immune system. The findings help explain why certain ...
Jun 18, 2026
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Rewired metabolism helps revive exhausted immune cells and boost cancer immunity
Researchers from National Taiwan University (NTU) and National Taiwan University Hospital (NTUH) have identified a promising way to reinvigorate the body's cancer-fighting immune cells by rewiring their metabolism, revealing ...
Jun 17, 2026
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Diabetes and obesity drugs may help with inflammation and repair of skin
GLP-1 receptor agonists are currently among the most widely discussed classes of drugs worldwide. They have gained popularity for their effectiveness in treating type 2 diabetes and obesity, but increasing evidence suggests ...
Jun 17, 2026
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An intranasal flu vaccine approved two decades ago may have underappreciated immune benefits
For decades, influenza vaccines have been judged largely by the antibodies they generate in the bloodstream, a measure that has remained the gold standard since the first flu immunizations were administered in the 1940s.
Immune cell circuit restores barrier function in inflammatory bowel disease
Scientists have discovered a new protective communication circuit between specialized immune cells in the intestines, a circuit that may be therapeutically targeted to improve inflammatory bowel disease outcomes, according ...
Jun 16, 2026
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Mapping immune cell interactions in gut tissue reveals changes in ulcerative colitis
In a new study published in Science Immunology, researchers at King's College London looked at a type of tissue important for the immune response called gut-associated lymphoid tissue (GALT), which is located within the lining ...
Jun 16, 2026
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Crohn's atlas maps gene shifts across more than 50 gut cell types
A detailed cellular study of Crohn's disease has mapped how gene activity changes across more than 50 cell types in the gut. The study provides an open resource of the genes that characterize each cell type and those whose ...
Jun 15, 2026
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In vivo CRISPR therapy successfully reduces hereditary angioedema attacks in first Phase III trial
Researchers from Amsterdam UMC, in collaboration with other hospitals, have successfully completed the first Phase III study of an in vivo CRISPR therapy. In this large-scale, double-blind trial, 80 patients with hereditary ...
Jun 15, 2026
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Genetic cause for rare skin condition points to new therapeutic option
An international team of researchers report in the journal Nature Immunology that a mutation in the gene OTULIN causes pediatric-onset pyoderma gangrenosum, characterized by recurrent ulcerating skin sores. They classify ...
Jun 15, 2026
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Why some immunotherapy fails: Tumor-triggered neutrophils can shut down cancer-killing T cells
Certain white blood cells in the immune system, known as neutrophils, can make cancer immunotherapy less effective, according to a new study from Karolinska Institutet published in the journal Immunity. The results show that ...
Jun 15, 2026
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Target with potential to improve CAR T-cell therapy response in patients with blood cancers identified
Researchers at the University of Maryland School of Medicine (UMSOM) have identified a target that may improve the response to CAR T-cell therapy, a treatment for patients with recurrent or difficult-to-treat blood cancers.
Jun 15, 2026
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Asthma attacks reshape airway tissue through mechanical stress, lung-on-a-chip reveals
About 25 million people in the U.S.—roughly eight out of 100—are diagnosed with asthma. Allergens, air pollution, extreme weather conditions and other irritants can cause chronic lung inflammation, leading to coughing, wheezing ...
Jun 15, 2026
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Immune activation may determine success of dual-target CAR T therapy in glioblastoma
Dual-target CAR T-cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes ...
Jun 15, 2026
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What to know about alpha-gal syndrome, the life-threatening meat allergy caused by tick bites
It's common knowledge that ticks can spread infections that cause serious illnesses, including Lyme disease. Now health officials are trying to raise awareness of a lesser-known problem: a life-threatening allergy to meat ...
Jun 15, 2026
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Killing cancer requires immune cells to infiltrate tumors' hostile microenvironment—sugar shields can help them break in
You might think of cancer as a mass of rogue cells that grow uncontrollably. But cancer is more organized and strategic than that. Rather, cancer is a tightly controlled cellular neighborhood that can keep the body's defenses ...
Jun 15, 2026
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Sugar-coated CAR-T cells survive longer and shrink lymphoma tumors in mice
Scientists at Florida International University may have found a way to make a powerful cancer treatment work even better. The treatment, called CAR-T therapy, uses a patient's own immune cells to fight cancer. Doctors remove ...
Jun 13, 2026
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Flu infection may weaken tuberculosis defenses by disrupting key immune pathways
New research from Imperial College London suggests that infection with the influenza virus may leave people more susceptible to tuberculosis. The findings suggest that seasonal flu vaccines could offer a potential new strategy ...
Jun 12, 2026
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Severe COVID-19 reveals distinct immune patterns tied to metabolism, not just antiviral response
Patients with COVID-19 can show several different antiviral immune response patterns, which may influence how the disease develops. This is shown in a new study from Karolinska Institutet, published in Genome Medicine, highlighting ...
Jun 12, 2026
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Teaching the immune system to fight aging
Maybe we shouldn't be surprised that so-called "zombie cells" come with a catch. In response to severe damage, when cells can't recover full function but aren't ready to die, they can become senescent, in a zombie-like state ...
Jun 12, 2026
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Supercharged natural killer cells suppress solid tumors in mice
Scientists have made great progress in harnessing the body's own immune cells to treat so-called liquid tumors, cancers of the blood and lymphatic system. Yet these powerful cell therapies have been no match for solid tumors, ...
Jun 11, 2026
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How body clock may shape inflammation, cancer risk and timing of future treatments
Daily life is shaped by the solar day, influencing when we wake up, eat, work and sleep. Inside the body, a similar internal timing system—present in nearly every cell—known as the circadian clock synchronizes many biological ...
Jun 11, 2026
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