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Immunology news
Oncology & Cancer
Predicting a rare but life-altering complication of common cancer treatment
A new study published in the Journal of Clinical Investigation has identified biomarkers that predict the likelihood of a patient developing checkpoint inhibitor-associated autoimmune diabetes before they are treated with ...
Nov 29, 2025
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Immunology
RSV vaccines could offer protection against asthma
Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases ...
Nov 28, 2025
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Healing the gut after cancer therapy: Immune cells turn damage into repair
Regulatory T cells (Treg cells), a specialized type of immune cell, are usually seen as "peacekeepers" that prevent excessive immune attacks. Surprisingly, a new study published in Signal Transduction and Targeted Therapy ...
Nov 28, 2025
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New protocol for Treg expansion uses targeted immunotherapy to reduce transplant complications
In preclinical studies, researchers found that priming the immune system with a Treg-expanding therapy before stem cell transplant boosted survival, protected vital organs, and promoted a balanced gut microbiome—offering ...
Nov 27, 2025
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Why certain arthritis drugs don't work in rheumatoid arthritis
Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...
Nov 26, 2025
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How a mitochondrial mutation rewires immune function
Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single ...
Nov 26, 2025
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Fighting two infections at once: Hepatitis C cure may relieve immune strain in HIV patients
The hepatitis C virus—HCV—can persist in the livers of those infected and even lead to liver disease or failure in extreme cases. It affects tens of millions of people worldwide and there is no vaccine to prevent infection, ...
Nov 26, 2025
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How antibody therapy clears Alzheimer's plaques: Key immune mechanism identified
Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline. Researchers from VIB and KU Leuven have now demonstrated the ...
Nov 25, 2025
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Scientists develop one-product-fits-all immunotherapy for pancreatic cancer
Pancreatic cancer is among the deadliest forms of cancer, with most patients diagnosed after the disease has already spread throughout the body. The five-year survival rate for metastatic cases hovers around 2–3%, and median ...
Nov 25, 2025
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Why the 'gut brain' plays a central role for allergies
An international research team led by scientists from Bern and Charité—Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system.
Nov 25, 2025
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Newly identified immune cell type could hold key to preventing scar tissue buildup in wounds
Researchers at the University of Arizona have uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement. ...
Nov 25, 2025
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Myeloid mimicry enables kidney tumors to resist immunotherapy and worsen rapidly, study finds
Researchers at The University of Texas MD Anderson Cancer Center have found that renal medullary carcinoma (RMC) cells use an adaptive mechanism called "myeloid mimicry" to hide from the immune system and promote disease ...
Nov 25, 2025
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Too sick to socialize: How the brain and immune system promote staying in bed
"I just can't make it tonight. You have fun without me." Across much of the animal kingdom, when infection strikes, social contact shuts down. A new study details how the immune and central nervous systems implement this ...
Nov 25, 2025
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Research challenges idea that gene PTPN22 boosts production of interferons
A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide influences production of type 1 interferon, a workhorse of the immune system. The work is published in ...
Nov 25, 2025
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Much-needed new drug approved for deadliest blood cancer
Biomedical research that began at the University of Virginia School of Medicine has yielded a much-needed new treatment for patients with the deadliest form of blood cancer.
Nov 25, 2025
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Identifying people at higher risk of seasonal and thunderstorm asthma so they can start treatment early
Over the past few weeks in Victoria and other parts of Australia, we've been seeing some wild and stormy weather.
Nov 25, 2025
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How autoimmune encephalitis disrupts thinking, memory and everyday life
Have you ever found yourself searching for a word you should know, forgetting what you were just doing, or feeling mentally foggy for no obvious reason?
Nov 25, 2025
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Kimchi acts as a 'precision regulator' for the immune system, 12-week clinical trial suggests
Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change of seasons in current times, a clinical study has scientifically proven that kimchi, a traditional ...
Nov 24, 2025
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New study identifies key mechanism driving HIV-associated immune suppression
Researchers from the Institute of Human Virology (IHV) at the University of Maryland School of Medicine have discovered how a specific type of immune cell may contribute to the persistence of HIV infections. The finding offers ...
Nov 24, 2025
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Two parallel blood formation systems produce different immune and blood cells
It has only recently become known that two parallel systems of blood formation exist in the body, originating from different precursor cells. Researchers at the German Cancer Research Center (DKFZ) have developed a method ...
Nov 24, 2025
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Your gut's railway switch: How the 'second brain' decides between attack and repair
Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the ...
Nov 24, 2025
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Certain immune cell subtypes drive lupus, study finds
Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine ...
Nov 24, 2025
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Sequencing method can analyze millions of T cells at a fraction of the cost
Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research Hospital. While T-cell analysis ...
Nov 24, 2025
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Scientists reverse aging in blood stem cells by targeting lysosomal dysfunction
Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough, published in Cell Stem ...
Nov 24, 2025
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Key immune differences in triple-negative breast cancer uncovered
Researchers at the LSU LCMC Health Cancer Center have published findings in npj Breast Cancer that shed new light on triple-negative breast cancer (TNBC), one of the most aggressive forms of breast cancer.
Nov 24, 2025
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