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Immunology news
Medical research
Two parallel blood formation systems produce different immune and blood cells
It has only recently become known that two parallel systems of blood formation exist in the body, originating from different precursor cells. Researchers at the German Cancer Research Center (DKFZ) have developed a method ...
3 hours ago
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HIV & AIDS
New study identifies key mechanism driving HIV-associated immune suppression
Researchers from the Institute of Human Virology (IHV) at the University of Maryland School of Medicine have discovered how a specific type of immune cell may contribute to the persistence of HIV infections. The finding offers ...
4 hours ago
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Kimchi acts as a 'precision regulator' for the immune system, 12-week clinical trial suggests
Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change of seasons in current times, a clinical study has scientifically proven that kimchi, a traditional ...
4 hours ago
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Sequencing method can analyze millions of T cells at a fraction of the cost
Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research Hospital. While T-cell analysis ...
4 hours ago
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Your gut's railway switch: How the 'second brain' decides between attack and repair
Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the ...
5 hours ago
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Certain immune cell subtypes drive lupus, study finds
Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine ...
7 hours ago
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Scientists reverse aging in blood stem cells by targeting lysosomal dysfunction
Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough, published in Cell Stem ...
4 hours ago
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Key immune differences in triple-negative breast cancer uncovered
Researchers at the LSU LCMC Health Cancer Center have published findings in npj Breast Cancer that shed new light on triple-negative breast cancer (TNBC), one of the most aggressive forms of breast cancer.
4 hours ago
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Why monkey studies may mislead research on cancer immunotherapy drugs targeting TIGIT
A new study published in the Journal of Biological Chemistry from UC Davis Comprehensive Cancer Center finds that TIGIT, an immune checkpoint receptor targeted by cancer immunotherapy drugs, triggers a different response ...
4 hours ago
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Lupus may be triggered by a common virus: New research
About 5 million people worldwide live with the autoimmune condition lupus. This condition can cause a range of symptoms, including tiredness, fever, joint pain and a characteristic butterfly-shaped rash across the cheeks ...
5 hours ago
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Pattern of chronic rejection for liver transplants decoded
Liver transplants often save the lives of seriously ill patients. However, there remains a risk that the body will reject the new organ. Doctors distinguish between acute and chronic rejection. While acute rejection is easy ...
7 hours ago
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Macrophage-killing bacterial toxin weakens the gut's defenses against ulcerative colitis
Ulcerative colitis (UC) is one of the most common inflammatory bowel diseases, a lifelong condition that can cause chronic inflammation and ulcers in the lining of the large intestine. This can lead to symptoms such as rectal ...
Nasal nanomedicine delivers immune-boosting therapy to fight brain tumors
Researchers at Washington University School of Medicine in St. Louis, along with collaborators at Northwestern University, have developed a noninvasive approach to treat one of the most aggressive and deadly brain cancers. ...
Nov 22, 2025
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Not all immune cells are created equal: Memory T cells in tissues outlast those in blood
Memory T cells are a special type of white blood cell that "remember" past infections and vaccines, helping our bodies to quickly respond if we encounter the same germs again. These cells are found throughout the body: some ...
Nov 22, 2025
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What happens when your immune system hijacks your brain
"My year of unraveling" is how a despairing Christy Morrill described nightmarish months when his immune system hijacked his brain.
Nov 22, 2025
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New CAR T strategy targets most common form of heart disease
A pioneering preclinical study has shown that CAR T cell therapy—a personalized form of immunotherapy used in cancer treatment—could be a highly effective tool against atherosclerosis, the condition where a build-up of ...
Nov 21, 2025
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Hidden immune cells linked to early type 1 diabetes detected in lymph nodes
Type 1 diabetes (T1D) impacts nearly two million Americans, and by the time most people learn they have it, most of the body's insulin-producing cells are destroyed. Now, pinpointing a hidden group of immune "attack" cells ...
Nov 21, 2025
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How T cells transform to defend our organs
We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.
Nov 21, 2025
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Macrophages can act like neurons for faster muscle injury repair, study finds
At the cellular level, the mechanics of how muscle tissue repair occurs gets complicated. There are significant differences between, say, tearing a muscle in a sports injury versus muscle tissue wasting away from diseases ...
Nov 21, 2025
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How COVID-19 variants outsmart the immune system
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have created the most comprehensive map to date showing how antibodies attach to the SARS-CoV-2 virus, which causes COVID-19, and how viral mutations ...
Nov 21, 2025
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Marine bacteria show potent antitumor effects against colorectal cancer
A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium ...
Nov 21, 2025
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Rare mutation may predict strong immunotherapy response in colorectal cancer
A new study led by researchers at The University of Texas MD Anderson Cancer Center shows that a specific subset of mutations in the POLE gene is strongly associated with durable responses to immunotherapy in patients with ...
Nov 21, 2025
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New study highlights key findings on lung cancer surveillance rates
Despite recommendations for posttreatment surveillance in lung cancer patients, there is wide variability in the follow-up care that lung cancer patients receive. A recent study, led by senior author Leah Backhus, MD, MPH, ...
Nov 21, 2025
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Depression tied to immune system imbalance, not just brain chemistry
Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea. However, ...
Nov 20, 2025
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Engineered immune cells target and destroy glioblastoma in animal models
With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer. Until now, all available treatments, including immunotherapy—which involves strengthening the immune system ...
Nov 20, 2025
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