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Allergy and immunology news

How 'peacemakers' of the immune system could unlock long-term disease remission

"Peacemaker" immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science.

Biomarkers could help identify ICU patients at risk of chronic critical illness

New research, published in The Journal of Immunology, identifies biomarkers of a distinct immune profile that could be used to identify patients at risk for chronic critical illness (CCI) on admission to the intensive care ...

What a 'silenced' chromosome can tell us about autoimmunity

Systemic lupus erythematosus (SLE), the most common form of lupus, is an autoimmune disorder that occurs more frequently in women. Having multiple X chromosomes has been associated with an increased risk of developing lupus; ...

Mapping the hidden rules of a key immune sensor

The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for "stimulator of interferon genes." STING helps cells respond to infections, damaged DNA and cancer. When ...

Why pollution affects some asthma patients more than others

For many people with asthma, air-quality advisories are harbingers of worsening symptoms. But for reasons science has struggled to explain, the extent to which pollution exacerbates asthma varies widely from person to person.

Gut fungi may hold the key to treating asthma worldwide

Two new studies jointly published in Nature Communications reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric allergic diseases—and may be promising ...

How RSV manipulates the immune response in respiratory cells

Respiratory syncytial virus (RSV) can cause severe lower respiratory tract infections, particularly in newborns and older adults. How the virus manages to evade the immune system and what changes it triggers in infected cells ...

Can we cure asthma? Yes, and we have a plan

Asthma is conventionally viewed as "treatable but incurable." In other words, we can manage its symptoms but not reverse the underlying condition. But advances in science are challenging this view, and we think a cure may ...

Neuroimmune abnormalities may play a key role in fibromyalgia

Fibromyalgia is a complex disorder characterized primarily by chronic widespread pain, fatigue and other physical and cognitive symptoms. Although it affects millions of people worldwide, the underlying biological mechanisms ...