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Allergy and immunology news
How 'invisible' vaccine scaffolding boosts HIV immune response
One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics ...
15 hours ago
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Immune 'hijacking' by tumors can predict cancer evolution
Predicting tumor progression is one of the major challenges in oncology. Scientists at the University of Geneva (UNIGE) and the Ludwig Institute for Cancer Research have discovered that neutrophils, a type of immune cell, ...
15 hours ago
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Fatty acids found to influence immune defense during chronic infections
Our immune system implements an array of strategies to combat threatening infections. White blood cells called cytotoxic T lymphocytes or "CD8 T cells" are soldiers of the immune system, serving as defensive agents that fight ...
19 hours ago
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Targeting HIV's hidden reservoirs: Lab-enhanced natural killer cells show promise
More than 30 million people with HIV must take antiretroviral therapy (ART) medications daily to keep the virus under control, according to the Joint United Nations Programme on HIV/AIDS (UNAIDS). The drugs are effective ...
14 hours ago
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Overactive immune cells can worsen heart failure. Targeting them could offer new treatments
Around 64 million people worldwide suffer from heart failure, and nearly half die within the first five years of diagnosis due to a lack of effective treatments to stop the disease from getting worse.
9 hours ago
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Gut microbe-derived butyrate activates immune cells to enhance vaccine efficacy
A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing how butyrate—a short-chain fatty acid produced by gut commensal bacteria—enhances T follicular ...
18 hours ago
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Why antibiotic allergy labels deserve a second look
In modern medicine, antibiotics are among the most powerful tools for preventing and treating life-threatening bacterial infections. Their effectiveness, however, often depends on using the right drug at the right time. Recognizing ...
16 hours ago
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Five mutational 'fingerprints' could help predict how visible tumors are to the immune system
Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's not simply the number of tumor mutations that matters for immunotherapy, but the kind of mutation ...
19 hours ago
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Immune cells linked to Epstein-Barr virus may play a role in multiple sclerosis
Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million Americans. The work found ...
Feb 5, 2026
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A genetic blueprint for avoiding killer T cell exhaustion
A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune ...
Feb 4, 2026
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An off-the-shelf immunotherapy for targeting solid tumors: Ready-to-use CAR-NKT cells show promise
A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to treat multiple solid tumors. The study focused on engineered invariant natural killer T cells, or ...
Feb 4, 2026
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B cells join T cells to drive sight-threatening arthritis in children
A team led by UCL researchers with Great Ormond Street Hospital (GOSH) and Moorfields Eye Hospital, found B cells—alongside T cells—play a key role in arthritis-related eye disease (JIA uveitis), a condition that can ...
Feb 4, 2026
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A single skin gene helps build the body's first line of immune defense
Researchers at Ben-Gurion University of the Negev (BGU) have discovered that a gene long known for shaping the skin's physical barrier also plays a crucial role in building and maintaining the skin's immune defense. The findings, ...
Feb 3, 2026
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Yeast cells can be used for rapid testing of cancer immunotherapy
An international research team with strong participation from DTU has developed a new biotechnological platform that makes it possible to test and understand advanced cancer treatments much faster and cheaper than before. ...
Feb 3, 2026
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A more reliable platform to test antibody medicines
An international research consortium, led by scientists at VIB and UGent, has developed a new platform that could change how antibody medicines are tested and brought to patients. The work, published in Science Immunology, ...
Feb 2, 2026
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In developing immunity to allergens, a little 'dirty' goes a long way
Conventional wisdom has held for some time that children who grow up in environments rich with biodiversity—farms, homes with pets, rural settings in general—are less likely to have allergies. The thing nobody has ever ...
Jan 31, 2026
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Alternate path for inflammation could improve rheumatoid arthritis treatment
The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients.
Jan 30, 2026
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A benchmark for antibodies: Open dataset aims to standardize sequencing and measurement
Antibodies are the immune system's precision tools for recognizing and neutralizing viruses, bacteria and other foreign substances that can make us ill. These proteins circulate in the bloodstream and are built from chains ...
Jan 30, 2026
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How does long COVID develop? New piece of the puzzle found
How long COVID develops is still largely unknown. New molecular connections are revealed in a recent study led by the Center for Individualized Infection Medicine (CiiM), which is a joint institution of the Helmholtz Center ...
Jan 29, 2026
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Beyond the active site: A new way to regulate immune enzyme TREX1
The immune system must maintain a delicate balance to defend against harmful threats while avoiding excessive inflammation. When this balance is disrupted, immune responses can contribute to autoimmune diseases and cancer. ...
Jan 29, 2026
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Targeting the gut's immune system could tackle early stages of Parkinson's
New research reveals how Parkinson's spreads from the gut to the brain, with the help of immune cells—offering a new potential therapeutic strategy—in a study in mice led by scientists at the UK Dementia Research Institute ...
Jan 28, 2026
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DNA research uncovers 22 genes that could put people at risk of long-term health conditions
Baylor College of Medicine researchers are part of a collaborative research group with AstraZeneca and Memorial Sloan Kettering Cancer Center that have identified 22 genes which increase the risk of developing a range of ...
Jan 28, 2026
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CAR T-cell therapy improves symptoms of myasthenia gravis, clinical trial shows
A new study led by researchers at the UNC School of Medicine and Cartesian Therapeutics, found that immunotherapy can help people with generalized myasthenia gravis, a disease where the body accidentally attacks the cells ...
Jan 28, 2026
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Interferon signal reprograms macrophage mitochondria to promote inflammation resolution, finds study
When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. But it is just as important to resolve that inflammation and return to homeostasis. Macrophages ...
Jan 28, 2026
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Innovations in asthma care can improve the health of Detroiters living with this chronic disease
Researchers and doctors are beginning to modernize asthma treatment using innovative therapies.
Jan 28, 2026
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