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Allergy and immunology news
Long dismissed in adult health, the thymus may be critical for longevity and cancer treatment
Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant in adulthood. ...
5 hours ago
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Scientists create cancer-fighting immune cells right in the body
For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an elaborate process: Doctors extract a patient's immune cells, ship them to a specialized facility where ...
5 hours ago
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Cellular stress signal found to drive immune exhaustion and weaken cancer therapy
Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress ...
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Scientists track real-time signaling in T cell activation to show how the immune system defends against threats
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the earliest moments of ...
Study identifies inflammatory immune pathway driving immunotherapy resistance in bladder cancer
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy. Their ...
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Brain tumors hijack sugar metabolism to evade immune attack, study shows
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published in the Proceedings ...
22 hours ago
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Implantable 'charging station' boosts fight against cancer
Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease. But many engineered immune cells lose strength quickly after they enter the body, especially inside tumors that actively ...
23 hours ago
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COVID-19 may increase the risk of glandular fever, study shows
Even individuals who did not become seriously ill with COVID-19 may have developed a weakened immune system that could lead to serious illnesses in the future. Research from Örebro University suggests that the coronavirus ...
23 hours ago
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Math can tell you how to manage your eczema
Anyone with a chronic illness understands the struggle of living with a disease that is deeply unpredictable. Many such illnesses are characterized by long periods of remission broken up by sudden, debilitating flare-ups. ...
Mar 17, 2026
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A novel immune cell subset that controls muscle regeneration and ossification
Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's structural support, increasing ...
Mar 17, 2026
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Universal, ready-to-use immunotherapy detects and destroys endometrial cancer in preclinical tests
Endometrial cancer is the most common gynecologic cancer in the United States and is one of the few cancers in which survival rates have steadily declined over the last few decades. The most aggressive subtypes are a significant ...
Mar 16, 2026
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Here's what you need to know about cancer vaccine development
Cancer is the second-leading cause of death in the United States, accounting for over 613,000 fatalities in 2023, per the Centers for Disease Control. But the field of cancer vaccines, which can be used as a form of treatment, ...
Mar 16, 2026
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The uterus' immune system can regenerate after transplantation, study shows
The immune system in the uterus can regenerate after both uterus transplantation and bone marrow transplantation. This is shown by a new study from Karolinska Institutet. The new insights into how the uterine immune environment ...
Mar 12, 2026
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Anchoring a key immune molecule makes T cells hit harder
Researchers at the Kennedy Institute of Rheumatology have found that physically resisting the formation of an immunological synapse actually promotes a stronger immune response. The findings could help explain how immune ...
Mar 12, 2026
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Tuning T cells' cancer-killing power via an engineered hydrogel platform
Lymph nodes, considered the command centers of our immune system, often get swollen and stiff when fighting infection. Now, a UC Berkeley-led team of researchers has discovered that this mechanical change may help instruct ...
Mar 12, 2026
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How bacteria suppress immune defenses in stubborn wound infections
Researchers have revealed how a common bacterium, Enterococcus faecalis (E. faecalis), releases lactic acid to acidify its surroundings and suppress the immune-cell signal needed to start a proper response to infection. By ...
Mar 12, 2026
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Dupilumab restores skin barrier function in children with moderate-to-severe atopic dermatitis, study shows
A new study led by investigators at National Jewish Health and published in Annals of Allergy, Asthma & Immunology shows that treatment with dupilumab significantly restores skin barrier function and reduces inflammation ...
Mar 12, 2026
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Pediatric allergy specialist: Feed babies allergenic foods earlier, not later
In January 2026, the U.S. Department of Agriculture released new Dietary Guidelines for Americans, 2025–2030.
Mar 12, 2026
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Experimental chemo drug triggers 'viral mimicry' signals that rally immune attack
In recent years, scientists have discovered that some chemotherapy drugs not only kill cancer cells directly, but at least in some patients, mysteriously also trigger their immune system to attack the cancer. That would seem ...
Mar 11, 2026
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Could a hot cup of matcha dial down the 'sneeze switch' in allergic rhinitis?
There's now another reason to love Japan's famous matcha: A study in mice suggests that the green tea powder could reduce the need to sneeze in people with nasal allergies.
Mar 11, 2026
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Previously hidden immune circuit in the uterus sheds light on preeclampsia and early pregnancy failure
Early pregnancy depends on a remarkable act of coordination. Before the placenta can nourish a growing fetus, the embryo must securely "land" and connect with the mother's blood supply—a process guided by a specialized ...
Mar 11, 2026
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How one flu virus can hamper the immune response to another
Prior exposure to one strain of influenza virus may weaken children's ability to mount an effective antibody response against their subsequent exposure to a different flu strain, according to a study led by Weill Cornell ...
Mar 11, 2026
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Turning cancer's protein machinery against itself to boost immunity
A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response. Researchers ...
Mar 11, 2026
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Immune cells play key role in regulating eye pressure linked to glaucoma, research reveals
When the eye's drainage system clogs, pressure builds up and causes damage. The pressure can lead to glaucoma and vision loss. New research, published in the journal Immunity, reveals that a specialized set of immune cells ...
Mar 9, 2026
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Blood immune 'fingerprint' may help predict serious side effects of new Alzheimer's drug
A team of University of Kentucky researchers has uncovered a surprising clue in the battle against Alzheimer's disease that could help doctors predict, and ultimately prevent, a common side effect of the newest generation ...
Mar 9, 2026
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