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Allergy and immunology news
New Tfr cell model uncovers molecular switches that restrain antibody responses
For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses ...
27 minutes ago
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AI framework helps identify new targets for CAR T cell therapy
Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that centers scientists' expertise to find viable target antigens for CAR T cell therapy. The work was led by ...
4 hours ago
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How 'peacemakers' of the immune system could unlock long-term disease remission
"Peacemaker" immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science.
11 hours ago
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Stress-linked gut viruses may help tumors evade the immune system
Chronic psychological stress can help tumors evade immune attack through a chain of molecular events involving gut bacteria and viruses within those bacteria, according to a study led by Weill Cornell Medicine investigators. ...
3 hours ago
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Hidden thymus step may prime cancer-killing T cells earlier than expected
Researchers at Mayo Clinic have uncovered a previously hidden step in how the immune system prepares to fight cancer, a discovery that could help scientists develop more effective and longer-lasting cancer immunotherapies.
4 hours ago
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Biomarkers could help identify ICU patients at risk of chronic critical illness
New research, published in The Journal of Immunology, identifies biomarkers of a distinct immune profile that could be used to identify patients at risk for chronic critical illness (CCI) on admission to the intensive care ...
16 hours ago
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Immune cell–fibroblast crosstalk may be the key trigger of autoimmune diseases
In autoimmune disorders, immune cells targeting "self" proteins are mistakenly activated, resulting in abnormal expansion and responsiveness. These disorders are known to reduce patients' quality of life over a prolonged ...
21 hours ago
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Mapping the hidden rules of a key immune sensor
The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for "stimulator of interferon genes." STING helps cells respond to infections, damaged DNA and cancer. When ...
20 hours ago
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Gut-homing antibodies help protect against norovirus, paving path for new vaccines, therapies
As the leading cause of viral gastroenteritis worldwide, norovirus is an all too familiar ailment. Its telltale digestive upset—not to mention its reputation for being notoriously contagious—has earned it the nicknames "winter ...
Jun 24, 2026
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What a 'silenced' chromosome can tell us about autoimmunity
Systemic lupus erythematosus (SLE), the most common form of lupus, is an autoimmune disorder that occurs more frequently in women. Having multiple X chromosomes has been associated with an increased risk of developing lupus; ...
Jun 24, 2026
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Early immune clues that determine who develops TB may lead to new ways to intervene earlier and stop the disease
A quarter of the global population is estimated to have been infected with Mycobacterium tuberculosis, yet only 5%–10% of those infected go on to develop active tuberculosis (TB). "The big question has always been what distinguishes ...
Jun 24, 2026
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Hidden mechanism driving joint tissue growth in rheumatoid arthritis has been found
Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that plays a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into ...
Jun 24, 2026
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Immunotherapy may temporarily restore fertility in patients of premature menopause
A pilot study from Karolinska Institutet shows that immunotherapy may enable the stimulation of egg maturation in women with autoimmune POI (premature ovarian insufficiency)—a condition that usually leads to infertility. ...
Jun 24, 2026
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Parasitic worms may help scientists develop therapies for inflammatory conditions
A parasitic worm might be the impetus behind a new generation of medicine. In a recent review in published in Clinical & Translational Immunology, Neima Briggs, MD, Ph.D., instructor of medicine (infectious diseases) at Yale ...
Jun 24, 2026
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Why pollution affects some asthma patients more than others
For many people with asthma, air-quality advisories are harbingers of worsening symptoms. But for reasons science has struggled to explain, the extent to which pollution exacerbates asthma varies widely from person to person.
Jun 23, 2026
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Gut fungi may hold the key to treating asthma worldwide
Two new studies jointly published in Nature Communications reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric allergic diseases—and may be promising ...
Jun 23, 2026
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Chimeric RNA unique to women could influence health and wellness
Strange "chimeric" RNA once thought to be the product of cancer is actually an important controller of women's health, including influencing their susceptibility to infectious disease and autoimmune disorders, new University ...
Jun 23, 2026
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This natural compound may help boost vaccine responses in older adults
Researchers at NDORMS have found that a naturally occurring compound called spermidine may help improve vaccine responses in some older adults by reducing signs of immune system aging.
Jun 23, 2026
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Estrogen link could explain why women are more likely to suffer from Crohn's
Scientists from the University of Bath (UK) have shed new light on how Crohn's disease develops and why it affects people differently after finding new evidence of a link between a key immune system gene in the gut and signaling ...
Jun 23, 2026
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Mouse model reveals key inflammatory mechanism behind sleep apnea-related metabolic disease
Researchers at Marshall University have identified a potential immune mechanism contributing to metabolic dysfunction and insulin resistance associated with obstructive sleep apnea (OSA), offering new insight into how chronic ...
Jun 23, 2026
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Physical exercise could help modulate the immune response in type 1 diabetes
Type 1 diabetes is an autoimmune disease in which the immune system attacks the insulin-producing beta cells of the pancreas. Despite advances in glycemic control and the development of new immunotherapies, there is still ...
Jun 23, 2026
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Two patients with severe autoimmune disease remain relapse-free for over 15 years after stem cell transplant
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune condition in which the body's own defenses turn against the optic nerves and spinal cord. This confusion leads to inflammation that can rob people of their ...
Targeted IL-15 drug in patient testing revives exhausted T cells without triggering severe inflammation
For some people, cancer immunotherapies are life-changing. These treatments can turn the body's own immune system against a tumor, either eliminating it or shrinking it enough to make surgery possible. But these therapies ...
Jun 22, 2026
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How RSV manipulates the immune response in respiratory cells
Respiratory syncytial virus (RSV) can cause severe lower respiratory tract infections, particularly in newborns and older adults. How the virus manages to evade the immune system and what changes it triggers in infected cells ...
Jun 22, 2026
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Study in Drosophila reveals how the immune system adjusts development in response to excess sugar
Diets rich in sugars and fats are associated with metabolic disorders such as insulin resistance, chronic inflammation and diabetes. During development, these imbalances can have a particularly significant impact, as the ...
Jun 22, 2026
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