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Allergy and immunology news
Pilot trial suggests anti-inflammatory drug could help difficult-to-treat depression
Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding from a University of Bristol-led pilot randomized controlled clinical trial, published in JAMA ...
2 hours ago
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How dead tumor cells could make chemotherapy and radiotherapy work better
As tumors outgrow their blood and nutrient supplies, or respond to treatments like chemotherapy and radiotherapy, individual cancer cells die, exposing their internal scaffolds. These dead cells are an abundant source of ...
5 hours ago
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Study identifies key protein in immune cell exhaustion in cancer immunotherapy
CAR T-cell therapy is considered a milestone in personalized cancer treatment. In this approach, a patient's own immune cells are genetically modified to recognize and destroy tumor cells. While it has already shown impressive ...
20 hours ago
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Neutrophils manufacture schizophrenia-linked protein, according to new research
The most common white blood cells in your body—immune cells called neutrophils—can make a protein nobody knew they were making, Stanford Medicine investigators have discovered. That unexpected sighting joins a growing list ...
19 hours ago
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A new way to strengthen the body's defense against respiratory viruses
Researchers have discovered a new method to boost the body's natural ability to fight respiratory viruses, including respiratory syncytial virus (RSV), one of the leading causes of severe lung infections worldwide.
22 hours ago
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Newly designed peptides suggest safer immunotherapies are within reach
Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important cellular messengers. Calcium signals help regulate muscle contraction, neural function, immune cell ...
21 hours ago
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Nervous system helps lung cancer evade the immune system, study reveals
Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve ...
22 hours ago
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Severe asthma links to three recurring illness clusters across 2,700 patients in 11 countries
Most people living with severe asthma are also battling other health conditions that go under the radar, a major new study has found. Researchers analyzing data from thousands of patients discovered that the additional illnesses—which ...
18 hours ago
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How chemotherapy can backfire: An immune shift tied to tumor resistance and poorer outcomes
Chemotherapy can be life-saving for many patients, but not all tumors respond—and some that do, may eventually become resistant. Investigators at Houston Methodist have identified a possible explanation for this resistance, ...
May 18, 2026
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Researchers discover new clues to delaying type 1 diabetes
Thomas Delong, Ph.D., moved to Colorado from Germany two decades ago intent on one thing: understanding the origin of type 1 diabetes (T1D) and finding ways to stop it. Diagnosed at age 12 with the disease that affects 9.5 ...
May 18, 2026
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Links discovered between mitochondrial lipid deficiency and inflammation of the gut
Inflammatory bowel diseases occur when the delicate balance between the gut, the immune system, and the microbiota is disrupted. Until now, however, it was unclear whether harmful microbes or defects in the body's own immune ...
May 18, 2026
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Reversing T cell exhaustion improves effectiveness of myeloma immunotherapies
Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb, and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma. In two ...
May 18, 2026
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How lungs balance defense and damage by tuning responses to deeper threats
Barrier organs that form boundaries between the body and the outside environment, such as the lungs, skin, and intestines, face a difficult balancing act. They must respond quickly to threats such as infection, but they also ...
May 16, 2026
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Neuronal hyperactivity triggers severe autoimmune brain disorder, researchers discover
In a condition known as "IgLON5 encephalitis," the immune system mistakenly attacks cells in the brain. This leads to brain inflammation and neuronal damage, which can manifest as sleep disturbances, cognitive impairment, ...
May 15, 2026
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Friendly skin bacteria shut down inflammatory driver of eczema
Friendly skin bacteria could hold the key to stopping eczema in its tracks, according to a breakthrough by a team of UK and Japanese scientists. Their new study reveals harmless microbes living on our skin release powerful ...
May 14, 2026
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The liver's immune cells might be the key to curing hepatitis B
Fifteen years ago, doctors in Europe noticed a remarkable thing happening in people with chronic hepatitis B infections. When patients went off their medications, the virus started to come back—and then some of the patients ...
May 14, 2026
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Lab-designed molecule offers hope for celiac disease sufferers
A research project led by the Institute for Research in Nutrition and Food Safety (INSA) and the Faculty of Pharmacy and Food Sciences at the University of Barcelona, together with the Molecular Biology Institute of Barcelona ...
May 14, 2026
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Immune system overreaction linked to deadly flu in pregnancy
In most people, influenza stays in the upper respiratory tract—mainly the nose—and clears without spreading further. But during pregnancy, the virus can extend beyond the lungs into the cardiovascular system, increasing the ...
May 14, 2026
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Hidden genetic defect linked to Kaposi sarcoma for the first time
A new study has uncovered a genetic cause that may explain why some people develop Kaposi sarcoma despite having no apparent immune deficiency. The rare cancer, which forms in the cells lining blood vessels, is caused by ...
May 14, 2026
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Researchers identify molecule linked to treatment-resistant inflammatory bowel disease
Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly ...
May 13, 2026
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Breast cancer cells with doubled genomes may dodge immunotherapy by turning off key immune signals
An epigenetic mechanism by which tumors manage to hide from the body's immune defenses has just been described by an international scientific team led by the University of Liège and the Dana-Farber Cancer Institute. These ...
May 13, 2026
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A new approach to cancer vaccination yields more powerful T cells
MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines—an advance that could lead to much more powerful cancer vaccines and stronger protection against infectious diseases.
May 13, 2026
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Future cancer therapy could use immunity to clean up damaged DNA by modulating AUF1
Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair. In particular, the authors of a new paper demonstrated how the downregulation of AUF1 impairs DNA repair, followed ...
May 13, 2026
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New guideline aims to reduce severe allergic reactions to epilepsy drugs
Researchers from the Center of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx) have published a new prescribing guideline aimed at reducing the incidence of serious allergic reactions to common ...
May 13, 2026
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Genes linked to neuronal communication appear altered in immune cells of patients with depression
Neurons and white blood cells differ greatly in shape, function, and location within the body. However, researchers at the University of Sao Paulo (USP) in Brazil discovered that certain genes are equally dysregulated in ...
May 12, 2026
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