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Allergy and immunology news
Hidden kidney effects emerge in LRBA deficiency, with polyuria in some patients
LRBA deficiency has long been viewed primarily as an immune disorder, but researchers at Science Tokyo have found that the condition may also impair urinary concentrating ability. Using patient registry data from 43 individuals, ...
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Hay fever, antihistamines and the evidence on dementia risk
For millions of people around the world, pollen season means weeks of sneezing, itchy eyes, and a blocked or runny nose. The timing varies depending on where you live and which plants are in flower, but grass pollen is one ...
2 hours ago
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CAR-T cells enhanced with navigation system to penetrate lymph nodes more efficiently
Chimeric antigen receptor T-cell therapy, or CAR-T, has transformed treatment for blood cancers. The immunotherapy involves reprogramming a patient's own immune cells to recognize and attack tumor cells. It offers many patients ...
23 hours ago
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Engineered stem cells reverse new-onset type 1 diabetes in mice
A group of researchers at the Medical University of South Carolina (MUSC) has recently developed a new stem cell therapy with a remarkable ability to reverse new-onset type 1 diabetes (T1D) in a mouse model of the disease. ...
Jun 7, 2026
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Common arthritis drugs reduce systemic Sjögren's disease activity in 24 weeks
A combination of two widely available anti-rheumatic drugs offers the first effective and affordable treatment for patients with Sjögren's disease with systemic disease activity, according to new results from a clinical trial ...
Jun 6, 2026
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Creatine may supercharge immune cells that are key to fighting cancer
Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical class of immune cells that activate and prepare the body's key cancer-fighters, according to new UCLA ...
Jun 5, 2026
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Yes, you really can be allergic to exercise—and the symptoms can be serious
People who don't like to workout will sometimes joke that they're "allergic" to exercise. But what many don't realize is that an allergy to exercise is a real thing—and it can be dangerous if not caught in time.
Jun 5, 2026
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Can you really drain your lymphatic system, and should you?
Did you know your body has an inbuilt sewerage system? It's called the lymphatic system, and is a crucial part of how your body fights infection and disease. Lately, the lymphatic system is causing a stir online, with some ...
Jun 5, 2026
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New drug cuts relapse risk by half in rare immune disorder trial
Stanford Medicine researchers and their colleagues found that a new drug, obexelimab, significantly reduces the risk of relapse in patients with IgG4-related disease, a rare chronic immune condition often misdiagnosed as ...
Jun 4, 2026
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Immune barrier may explain why mRNA shots struggle to block nasal infection
A consistent biological barrier that stops the immune system from making the antibodies most needed to protect the nose and throat from respiratory viruses has been identified. The discovery, led by researchers from the University ...
Jun 4, 2026
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How cells fight infection from the inside: Newly identified ADX pathway may broaden understanding of immunity
When thinking of the immune system, most people imagine white blood cells putting up a fight against invading germs in the bloodstream. But now, in research published in Molecular Cell, scientists detail a separate but equally ...
Jun 4, 2026
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Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies
An international research team has succeeded in elucidating key immunological and biochemical mechanisms underlying granulomatous skin diseases. The findings, recently published in Science Advances, identify new therapeutic ...
Jun 4, 2026
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Retraining the immune system to treat type 1 diabetes
Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pancreas, and destroys cells that would otherwise produce insulin, a hormone crucial for regulating blood ...
Jun 3, 2026
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New CAR T treatment opens door for patients in need of kidney transplant
A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants. These individuals were considered among the most difficult in the nation ...
Jun 3, 2026
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Study shows how the fetal environment may reduce the risk of type 1 diabetes
Researchers at Umeå University have shown in a new study that the environment in the womb can leave lasting imprints on the immune system and influence the risk of developing Type 1 diabetes, even when the genetic background ...
Jun 3, 2026
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New RNA sequencing method reveals hidden layer of immune system control
Researchers at University Medical Center Utrecht have uncovered a previously underappreciated mechanism that helps immune cells to respond rapidly to infections. Using advanced long-read RNA sequencing, the team shows that ...
Jun 2, 2026
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T cells may be key to stopping measles virus—and its deadly relatives
T cells are some of the immune system's most important warriors. They can stop tumor growth and even fight off severe infections. Now scientists at La Jolla Institute for Immunology (LJI) have discovered how T cells target ...
Jun 2, 2026
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Why some tumors resist immunotherapy: Blocking miR-25 may help turn 'cold' cancers 'hot'
Immune checkpoint therapy, a type of cancer immunotherapy that helps the immune system recognize and attack tumors, has transformed cancer treatment. While these therapies can produce long-lasting benefits for some patients, ...
Jun 1, 2026
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How cells clear immune signals could reshape drug design and cancer spread research
Our body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, that immune cells arrive exactly where they are needed. Many vital processes such as sensory perception, ...
Jun 1, 2026
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Cancer vaccine sustains 49% melanoma reduction after 5 years
The combination of a vaccine and a drug, which both harness the immune system to attack cancer cells, has proven successful in cutting the risk of skin cancer recurrence and death by 49%, a new study shows. This reduction ...
Jun 1, 2026
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Comprehensive atlas maps dendritic cells across cancers
Researchers from VIB, VUB, and an international network of collaborators have created the most comprehensive single-cell atlas to date of tumor-associated dendritic cells. By integrating data from 14 mouse tumor models and ...
Jun 1, 2026
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Microplastics altered allergy-related immune responses after 14 days in mouse lungs
Microplastics (MP) are the subject of intensive medical research, but little is yet known about their effects on the immune system. A study led by the Medical University of Vienna now shows that tiny particles of polyethylene ...
May 31, 2026
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Tezepelumab helps severe asthma patients reduce oral steroids over 28 weeks
New results from the Phase III SUNRISE clinical trial show that tezepelumab significantly reduced the need for long-term oral corticosteroid use in adults with severe oral corticosteroid-dependent asthma while maintaining ...
May 30, 2026
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Blood proteins flag multiple sclerosis years before diagnosis, opening a window for prevention
A new study has revealed a group of blood proteins that are altered in people who go on to develop multiple sclerosis (MS), in some cases more than a decade before diagnosis. The findings offer hope that a simple blood test ...
May 30, 2026
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