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Immunology news
Immunology
NeuMap: A pioneering map of neutrophils that redefines their role in health, infection and inflammation
Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage. Yet despite their importance, until now very little was known about how they truly function, how they change ...
23 hours ago
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Oncology & Cancer
Breast cancer remodels lymphatic vessels to accelerate its spread, research reveals
Breast cancer is able to modify the lymphatic vessels through which it travels to the draining lymph nodes. From there, it can then spread to other parts of the body. A new finding by Finnish researchers may help develop ...
23 hours ago
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Newly defined benign soft tissue tumor with bony shell may mimic malignancy
It's not often that a pathologist gets to make a diagnosis that works for the patient by preventing treatment from occurring. But thanks to a Johns Hopkins Medicine doctor and his newly reported definition and classification ...
19 hours ago
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FDA approves Imfinzi for early gastric and gastroesophageal cancers
The U.S. Food and Drug Administration has approved Imfinzi (durvalumab) in combination with standard-of-care FLOT chemotherapy (fluorouracil, leucovorin, oxaliplatin, and docetaxel) for treating adult patients with resectable, ...
12 hours ago
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FDA approves updated label for Unloxcyt
The U.S. Food and Drug Administration has approved an updated label for Unloxcyt (cosibelimab-ipdl) for the treatment of adults with metastatic or locally advanced cutaneous squamous cell carcinoma (CSCC) who are not candidates ...
15 hours ago
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Why stress can make your hair fall out: A two-part reaction
It's well known that stress can trigger hair loss. A new paper explores how this happens and how our response to stress can have long-term consequences for our scalps, research that may eventually yield insights into autoimmune ...
Dec 3, 2025
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FDA approves Padcev for muscle-invasive bladder cancer
The U.S. Food and Drug Administration has approved Pfizer's Padcev (enfortumab vedotin-ejfv), a Nectin-4 directed antibody-drug conjugate, as a perioperative neoadjuvant treatment and postcystectomy adjuvant treatment for ...
Dec 3, 2025
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Cancer-fighting bacterial product 'cocktails' may offer personalized treatment
Bacteria may be the next frontier in cancer treatment, according to a team led by researchers at Penn State that devised a new approach of creating bacteria-derived mixtures—or cocktails—to help fight bladder cancer. ...
Dec 2, 2025
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Blocking Claudin-4 protein may help immune system fight aggressive ovarian cancer
Scientists at The University of Texas at El Paso have found a promising new target in the fight against high-grade serous carcinoma, an aggressive form of ovarian cancer. Less than 50% of women survive five years after diagnosis, ...
Dec 2, 2025
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Study compares immune responses from three major COVID-19 vaccine types
A recent study has provided the first side-by-side comparison of how three major COVID-19 vaccine types differ in triggering immune responses and sustaining protection, according to an analysis published in JCI Insight.
Dec 2, 2025
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Why some people with HIV achieve remission after antibody treatment
Researchers led by a team from Mass General Brigham and the Ragon Institute have discovered why some people living with HIV who are given a treatment called broadly neutralizing anti-HIV antibodies (bNAbs) can safely stop ...
Dec 1, 2025
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Long-term HIV control: Combination therapy points way to a possible cure
A new study from UC San Francisco shows it may be possible to control HIV without long-term antiviral treatment—an advance that points the way toward a possible cure for a disease that affects 40 million people around the ...
Dec 1, 2025
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Inflammation and metabolic stress combine to drive a new cell death pathway—mitoxyperilysis
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, found that this combination ...
Dec 1, 2025
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Unexpected pathway for IgA antibody production may help improve vaccines
Scientists led by Stephanie Eisenbarth, MD, Ph.D., the Roy and Elaine Patterson Professor of Medicine and director of the Center for Human Immunobiology, have discovered how critical IgA antibodies are produced through unexpected ...
Dec 1, 2025
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A molecule opens a breach in HIV, providing access to its reservoirs
An international team led by two Université de Montréal researchers has unveiled how a molecule capable of opening the "shell" of HIV improves the elimination of infected cells.
Dec 1, 2025
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Study investigates treatment safety in cases of late HIV diagnosis
About 40 million people worldwide are living with HIV infection. In the United Kingdom, there are approximately 100,000 people affected. If the infection is not treated, the body will eventually be unable to defend itself ...
Dec 1, 2025
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Lack of dietary iron may impair immune cells' ability to fight influenza
New research published in The Journal of Immunology suggests that a lack of dietary iron can negatively affect the ability of immune cells to respond to viral infection in the lungs. In mice with dietary iron deficiency and ...
Dec 1, 2025
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How to stay healthy on HIV treatment, and what side effects to look out for
HIV treatment has delivered life-altering advantages. Antiretroviral therapy has led to a reduced mortality and improved life expectancy for people living with HIV. Nearly 41 million people were living with HIV in 2024. Eastern ...
Dec 1, 2025
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Predicting a rare but life-altering complication of common cancer treatment
A new study published in the Journal of Clinical Investigation has identified biomarkers that predict the likelihood of a patient developing checkpoint inhibitor-associated autoimmune diabetes before they are treated with ...
Nov 29, 2025
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RSV vaccines could offer protection against asthma
Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases ...
Nov 28, 2025
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Healing the gut after cancer therapy: Immune cells turn damage into repair
Regulatory T cells (Treg cells), a specialized type of immune cell, are usually seen as "peacekeepers" that prevent excessive immune attacks. Surprisingly, a new study published in Signal Transduction and Targeted Therapy ...
Nov 28, 2025
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New protocol for Treg expansion uses targeted immunotherapy to reduce transplant complications
In preclinical studies, researchers found that priming the immune system with a Treg-expanding therapy before stem cell transplant boosted survival, protected vital organs, and promoted a balanced gut microbiome—offering ...
Nov 27, 2025
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Why certain arthritis drugs don't work in rheumatoid arthritis
Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...
Nov 26, 2025
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How a mitochondrial mutation rewires immune function
Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single ...
Nov 26, 2025
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Fighting two infections at once: Hepatitis C cure may relieve immune strain in HIV patients
The hepatitis C virus—HCV—can persist in the livers of those infected and even lead to liver disease or failure in extreme cases. It affects tens of millions of people worldwide and there is no vaccine to prevent infection, ...
Nov 26, 2025
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