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Allergy and immunology news
New drug cuts relapse risk by half in rare immune disorder trial
Stanford Medicine researchers and their colleagues found that a new drug, obexelimab, significantly reduces the risk of relapse in patients with IgG4-related disease, a rare chronic immune condition often misdiagnosed as ...
12 hours ago
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Immune barrier may explain why mRNA shots struggle to block nasal infection
A consistent biological barrier that stops the immune system from making the antibodies most needed to protect the nose and throat from respiratory viruses has been identified. The discovery, led by researchers from the University ...
15 hours ago
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How cells fight infection from the inside: Newly identified ADX pathway may broaden understanding of immunity
When thinking of the immune system, most people imagine white blood cells putting up a fight against invading germs in the bloodstream. But now, in research published in Molecular Cell, scientists detail a separate but equally ...
16 hours ago
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Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies
An international research team has succeeded in elucidating key immunological and biochemical mechanisms underlying granulomatous skin diseases. The findings, recently published in Science Advances, identify new therapeutic ...
12 hours ago
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Retraining the immune system to treat type 1 diabetes
Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pancreas, and destroys cells that would otherwise produce insulin, a hormone crucial for regulating blood ...
Jun 3, 2026
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New CAR T treatment opens door for patients in need of kidney transplant
A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants. These individuals were considered among the most difficult in the nation ...
Jun 3, 2026
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Study shows how the fetal environment may reduce the risk of type 1 diabetes
Researchers at Umeå University have shown in a new study that the environment in the womb can leave lasting imprints on the immune system and influence the risk of developing Type 1 diabetes, even when the genetic background ...
Jun 3, 2026
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New RNA sequencing method reveals hidden layer of immune system control
Researchers at University Medical Center Utrecht have uncovered a previously underappreciated mechanism that helps immune cells to respond rapidly to infections. Using advanced long-read RNA sequencing, the team shows that ...
Jun 2, 2026
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T cells may be key to stopping measles virus—and its deadly relatives
T cells are some of the immune system's most important warriors. They can stop tumor growth and even fight off severe infections. Now scientists at La Jolla Institute for Immunology (LJI) have discovered how T cells target ...
Jun 2, 2026
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Why some tumors resist immunotherapy: Blocking miR-25 may help turn 'cold' cancers 'hot'
Immune checkpoint therapy, a type of cancer immunotherapy that helps the immune system recognize and attack tumors, has transformed cancer treatment. While these therapies can produce long-lasting benefits for some patients, ...
Jun 1, 2026
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How cells clear immune signals could reshape drug design and cancer spread research
Our body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, that immune cells arrive exactly where they are needed. Many vital processes such as sensory perception, ...
Jun 1, 2026
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Cancer vaccine sustains 49% melanoma reduction after 5 years
The combination of a vaccine and a drug, which both harness the immune system to attack cancer cells, has proven successful in cutting the risk of skin cancer recurrence and death by 49%, a new study shows. This reduction ...
Jun 1, 2026
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Comprehensive atlas maps dendritic cells across cancers
Researchers from VIB, VUB, and an international network of collaborators have created the most comprehensive single-cell atlas to date of tumor-associated dendritic cells. By integrating data from 14 mouse tumor models and ...
Jun 1, 2026
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Microplastics altered allergy-related immune responses after 14 days in mouse lungs
Microplastics (MP) are the subject of intensive medical research, but little is yet known about their effects on the immune system. A study led by the Medical University of Vienna now shows that tiny particles of polyethylene ...
May 31, 2026
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Tezepelumab helps severe asthma patients reduce oral steroids over 28 weeks
New results from the Phase III SUNRISE clinical trial show that tezepelumab significantly reduced the need for long-term oral corticosteroid use in adults with severe oral corticosteroid-dependent asthma while maintaining ...
May 30, 2026
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Blood proteins flag multiple sclerosis years before diagnosis, opening a window for prevention
A new study has revealed a group of blood proteins that are altered in people who go on to develop multiple sclerosis (MS), in some cases more than a decade before diagnosis. The findings offer hope that a simple blood test ...
May 30, 2026
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Traffic and industrial pollutants tied to chronic rhinosinusitis risk
Long-term residential exposure to traffic-related and industry-related pollutants is associated with increased chronic rhinosinusitis (CRS) risk, according to a study published online May 28 in JAMA Otolaryngology-Head & ...
May 29, 2026
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Scientists validate a link between autoimmunity and long COVID
A Mount Sinai-led research team has demonstrated that autoimmunity, in which the body's immune system attacks its own tissues, is responsible for the often-debilitating and confounding symptoms of long COVID in a subset of ...
May 28, 2026
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Gut microbe found to worsen sepsis by triggering hyperinflammatory immune responses
Why do some people recover easily from bacterial infections while others rapidly deteriorate into life-threatening sepsis? According to a new study published in Nature Communications, the answer may lie not only in the invading ...
May 28, 2026
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Immune 'energy signature' linked to tuberculosis may explain why some individuals control infection
Researchers at Trinity College Dublin have identified key differences in how immune cells generate and use energy, a process known as cellular metabolism, in people with latent versus active tuberculosis (TB). The findings ...
May 28, 2026
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AI-powered atlas reveals new insights into tertiary lymphoid structures as prognostic and response biomarkers in cancer
In a study published in Science, researchers from The University of Texas MD Anderson Cancer Center have developed a spatial atlas of specialized immune structures, called tertiary lymphoid structures (TLSs), across multiple ...
May 28, 2026
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Unexpected allies: Eosinophils may help predict cancer immunotherapy response and survival
Long regarded as cells involved primarily in allergic responses and antiparasitic defense, eosinophils are now drawing increasing attention in oncology. A review article led by Marie Gilon, an oncology resident physician ...
May 28, 2026
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How an aging immune system loses control over the gut microbiome
Trillions of microorganisms live in the human gut, collectively forming the gut microbiome. They support important bodily functions, including digestion, metabolism, and the immune system. While this microbial community remains ...
May 27, 2026
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How inflammation can worsen artery plaque and also hold it back
A new LMU study shows how different immune cells variously influence the formation of dangerous vascular deposits—and identifies miR-147 as a potential starting point for future therapies.
May 27, 2026
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New studies describe how immune modulation can effectively combat Valley Fever
Valley Fever, technically known as Coccidioidomycosis, is a dust-borne fungal infection that occurs in dry regions like the southwestern US and is proliferating in California and Arizona. California alone spends $1 billion ...
May 27, 2026
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