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Allergy and immunology news

Blocking both drug-resistant bacteria and influenza with a broad-spectrum infection prevention approach

Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine. In particular, mixed bacterial-viral infections in critically ill or immunocompromised ...

Mouse study reveals local antibody 'brakes' shape B cell selection

A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together with the Schief Lab at Scripps Research Institute, has uncovered a previously unrecognized mechanism that shapes ...

Optimizing CAR T-cell therapy to tackle solid tumors

In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite prostaglandin E2 can block T cells—the killer cells of the immune system—in the vicinity of a tumor, ...

Rallying more T-cells to immunotherapy's fight against cancer

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't respond to this immunotherapy for reasons not yet fully understood. Australian scientists have found ...

Shining new light on how cytokines manage immune response

Scientists in the Blavatnik Institute at Harvard Medical School and MIT have created a new family of tools that, for the first time, illuminates the missing half of how the immune system uses molecules called cytokines to ...