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Allergy and immunology news

Thymus-derived hormone may suppress age-related inflammation and boost cancer therapy

Chronic, low-grade inflammation in the body—a phenomenon known as "inflammaging" because it increases with age—has been linked to many of today's leading causes of illness and death, including cancer, heart disease, metabolic ...

Researchers uncover 'hidden key' to immunotherapy for intractable brain tumors

Researchers have uncovered a clue to why immune checkpoint inhibitors—cancer therapies that release the immune "brakes" exploited by tumors to evade attack—show limited efficacy in some brain tumors. A KAIST research team ...

Long non-coding RNA emerges as a 'kill switch' for macrophages

Macrophages are considered the "scavenger cells" of the immune system, but some pathogens exploit these very cells as hiding places. Researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg ...

Building a blueprint to manipulate the immune system

Why do some vaccines protect for a lifetime, while threats like tumors and viruses present such an ongoing challenge? The answer lies in the immune system's memory and how invading pathogens hack the system.

Blood vessels guide immune cells to metastases

It has long been suspected that endothelial cells, the specialized cells lining the inner walls of blood vessels, play a key role in determining how the body's immune system responds to tumors. Researchers at the German Cancer ...