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Allergy and immunology news
Tezepelumab helps severe asthma patients reduce oral steroids over 28 weeks
New results from the Phase III SUNRISE clinical trial show that tezepelumab significantly reduced the need for long-term oral corticosteroid use in adults with severe oral corticosteroid-dependent asthma while maintaining ...
12 hours ago
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Blood proteins flag multiple sclerosis years before diagnosis, opening a window for prevention
A new study has revealed a group of blood proteins that are altered in people who go on to develop multiple sclerosis (MS), in some cases more than a decade before diagnosis. The findings offer hope that a simple blood test ...
18 hours ago
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Traffic and industrial pollutants tied to chronic rhinosinusitis risk
Long-term residential exposure to traffic-related and industry-related pollutants is associated with increased chronic rhinosinusitis (CRS) risk, according to a study published online May 28 in JAMA Otolaryngology-Head & ...
May 29, 2026
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Scientists validate a link between autoimmunity and long COVID
A Mount Sinai-led research team has demonstrated that autoimmunity, in which the body's immune system attacks its own tissues, is responsible for the often-debilitating and confounding symptoms of long COVID in a subset of ...
May 28, 2026
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Immune 'energy signature' linked to tuberculosis may explain why some individuals control infection
Researchers at Trinity College Dublin have identified key differences in how immune cells generate and use energy, a process known as cellular metabolism, in people with latent versus active tuberculosis (TB). The findings ...
May 28, 2026
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Gut microbe found to worsen sepsis by triggering hyperinflammatory immune responses
Why do some people recover easily from bacterial infections while others rapidly deteriorate into life-threatening sepsis? According to a new study published in Nature Communications, the answer may lie not only in the invading ...
May 28, 2026
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AI-powered atlas reveals new insights into tertiary lymphoid structures as prognostic and response biomarkers in cancer
In a study published in Science, researchers from The University of Texas MD Anderson Cancer Center have developed a spatial atlas of specialized immune structures, called tertiary lymphoid structures (TLSs), across multiple ...
May 28, 2026
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Unexpected allies: Eosinophils may help predict cancer immunotherapy response and survival
Long regarded as cells involved primarily in allergic responses and antiparasitic defense, eosinophils are now drawing increasing attention in oncology. A review article led by Marie Gilon, an oncology resident physician ...
May 28, 2026
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How an aging immune system loses control over the gut microbiome
Trillions of microorganisms live in the human gut, collectively forming the gut microbiome. They support important bodily functions, including digestion, metabolism, and the immune system. While this microbial community remains ...
May 27, 2026
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New studies describe how immune modulation can effectively combat Valley Fever
Valley Fever, technically known as Coccidioidomycosis, is a dust-borne fungal infection that occurs in dry regions like the southwestern US and is proliferating in California and Arizona. California alone spends $1 billion ...
May 27, 2026
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How inflammation can worsen artery plaque and also hold it back
A new LMU study shows how different immune cells variously influence the formation of dangerous vascular deposits—and identifies miR-147 as a potential starting point for future therapies.
May 27, 2026
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Human monoclonal antibodies fight antimicrobial resistance during disease treatment
The overuse of antibiotics is increasingly leading to the emergence of infectious superbugs—dangerous bacteria that have developed antimicrobial resistance (AMR) and are therefore much harder, if not impossible, to eliminate ...
May 27, 2026
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CAR T moves beyond cancer, targeting autoimmune disease with immune system reset
At age 49, Jan Janisch-Hanzlik's multiple sclerosis was destroying her freedom to live the life she wanted. She gave up her active nursing job for a desk role. Frequent falls made her afraid to carry her grandchildren. She ...
May 26, 2026
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Immune memory cells in ovarian cancer produce tumor-targeting antibodies, opening a vaccine path
While we tend to quickly forget having been ill or having received a vaccine, the immune system remembers remarkably well. It has memory B cells—"trained" immune cells that circulate throughout the body in search of harmful ...
May 26, 2026
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How 'Pac-Man' cells fail to prevent deadly infection risk in people with cystic fibrosis
Researchers have discovered how part of the body's immune system could better combat a leading cause of death for people with cystic fibrosis (CF). A team led by The University of Queensland's Professor Peter Sly and Dr. ...
May 26, 2026
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Mitochondria may control immune cell activation and the effectiveness of immunotherapy
A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial checkpoint that enables dendritic cells to efficiently activate T lymphocytes against viruses and ...
May 22, 2026
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COVID-19 mRNA vaccine plus immune system enhancer may reduce need for repeated boosters, say researchers
In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, improved the duration ...
May 22, 2026
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Key gene boundary discovery may improve treatment of rare inflammatory disorder
Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works. Researchers from Hiroshima University have identified a critical boundary within the immune-regulating gene ...
May 22, 2026
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Scientists capture 'housekeeping' immune cells attacking live melanoma
Scientists at the Garvan Institute of Medical Research have captured, for the first time, "housekeeping" immune cells actively attacking and engulfing live melanoma cells—a discovery that could change the way we approach ...
May 21, 2026
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Scientists discover how to harness T cells to combat entire viral families
Scientists at La Jolla Institute for Immunology (LJI) have discovered that combining key vaccine ingredients could give the body the tools it needs to fight the entire family of arenaviruses with a single vaccine. This "pan-arenavirus" ...
May 21, 2026
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Gut bacteria linked to immunotherapy success in melanoma patients
Researchers at The George Washington University, working with Weill Cornell Medicine, have identified specific gut bacteria linked to better responses to cancer immunotherapy in patients with advanced melanoma. The study ...
May 21, 2026
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Elite immune cells lead the fight against multiple myeloma
Immunotherapy for cancer works like a guided missile, directing the body's immune cells toward tumor cells. However, not all immune cells respond to the call to attack, and this can lead to variability in treatment responses. ...
May 21, 2026
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Pilot trial suggests anti-inflammatory drug could help difficult-to-treat depression
Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding from a University of Bristol-led pilot randomized controlled clinical trial, published in JAMA ...
May 20, 2026
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New technique discovers previously unknown population of immune cells in the Alzheimer's brain
A newly developed microscopy technique allows, for the first time, the visualization of more than 30 protein markers simultaneously in the human brain and uses bioinformatics to analyze their spatial relationships. In the ...
May 20, 2026
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How dead tumor cells could make chemotherapy and radiotherapy work better
As tumors outgrow their blood and nutrient supplies, or respond to treatments like chemotherapy and radiotherapy, individual cancer cells die, exposing their internal scaffolds. These dead cells are an abundant source of ...
May 20, 2026
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