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Allergy and immunology news
New 'fishhook' bonds help T cells stick longer to prostate cancer cells
UCLA and Stanford Medicine researchers, in collaboration with scientists from the University of Utah and Columbia University, have engineered a new class of supercharged T cells that are stronger, longer-lasting, and more ...
7 hours ago
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Switching from milk to solid food in early life helps reprogram the gut's immune defenses, researchers find
According to a team of researchers at Baylor College of Medicine, Tongji University and collaborating institutions, weaning or switching from milk to solid food in early life doesn't just change what babies eat, it helps ...
15 hours ago
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AI helps to evaluate skin lesions in rare disease more accurately
There is a promising new drug for the rare disease mastocytosis, which is associated with skin lesions, among other things. Researchers at the University of Basel have now been able to use artificial intelligence to quantitatively ...
9 hours ago
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Masked T‑cell engagers: Cancer immunotherapies for the future?
A new immunotherapy drug has demonstrated early promise in a recent prostate cancer clinical trial. The drug, called VIR-5500, is a "masked T-cell engager." This type of immunotherapy ignites our own immune arsenal to fight ...
3 hours ago
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Scientists track real-time signaling in T cell activation to show how the immune system defends against threats
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the earliest moments of ...
Scientists create cancer-fighting immune cells right in the body
For years, one of the most powerful weapons against certain blood cancers, called CAR-T cell therapy, has required an elaborate process: Doctors extract a patient's immune cells, ship them to a specialized facility where ...
Mar 18, 2026
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Long dismissed in adult health, the thymus may be critical for longevity and cancer treatment
Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant in adulthood. ...
Mar 18, 2026
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Cellular stress signal found to drive immune exhaustion and weaken cancer therapy
Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress ...
Mar 18, 2026
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Cancer drug protein target may also help fight influenza
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX). Published in Cell Reports, the study found that Programmed Death-Ligand ...
Mar 18, 2026
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Study identifies inflammatory immune pathway driving immunotherapy resistance in bladder cancer
Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy. Their ...
Mar 18, 2026
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Brain tumors hijack sugar metabolism to evade immune attack, study shows
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published in the Proceedings ...
Mar 17, 2026
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Implantable 'charging station' boosts fight against cancer
Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease. But many engineered immune cells lose strength quickly after they enter the body, especially inside tumors that actively ...
Mar 17, 2026
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Math can tell you how to manage your eczema
Anyone with a chronic illness understands the struggle of living with a disease that is deeply unpredictable. Many such illnesses are characterized by long periods of remission broken up by sudden, debilitating flare-ups. ...
Mar 17, 2026
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COVID-19 may increase the risk of glandular fever, study shows
Even individuals who did not become seriously ill with COVID-19 may have developed a weakened immune system that could lead to serious illnesses in the future. Research from Örebro University suggests that the coronavirus ...
Mar 17, 2026
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A novel immune cell subset that controls muscle regeneration and ossification
Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's structural support, increasing ...
Mar 17, 2026
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Universal, ready-to-use immunotherapy detects and destroys endometrial cancer in preclinical tests
Endometrial cancer is the most common gynecologic cancer in the United States and is one of the few cancers in which survival rates have steadily declined over the last few decades. The most aggressive subtypes are a significant ...
Mar 16, 2026
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Here's what you need to know about cancer vaccine development
Cancer is the second-leading cause of death in the United States, accounting for over 613,000 fatalities in 2023, per the Centers for Disease Control. But the field of cancer vaccines, which can be used as a form of treatment, ...
Mar 16, 2026
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Tuning T cells' cancer-killing power via an engineered hydrogel platform
Lymph nodes, considered the command centers of our immune system, often get swollen and stiff when fighting infection. Now, a UC Berkeley-led team of researchers has discovered that this mechanical change may help instruct ...
Mar 12, 2026
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The uterus' immune system can regenerate after transplantation, study shows
The immune system in the uterus can regenerate after both uterus transplantation and bone marrow transplantation. This is shown by a new study from Karolinska Institutet. The new insights into how the uterine immune environment ...
Mar 12, 2026
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Anchoring a key immune molecule makes T cells hit harder
Researchers at the Kennedy Institute of Rheumatology have found that physically resisting the formation of an immunological synapse actually promotes a stronger immune response. The findings could help explain how immune ...
Mar 12, 2026
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How bacteria suppress immune defenses in stubborn wound infections
Researchers have revealed how a common bacterium, Enterococcus faecalis (E. faecalis), releases lactic acid to acidify its surroundings and suppress the immune-cell signal needed to start a proper response to infection. By ...
Mar 12, 2026
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Dupilumab restores skin barrier function in children with moderate-to-severe atopic dermatitis, study shows
A new study led by investigators at National Jewish Health and published in Annals of Allergy, Asthma & Immunology shows that treatment with dupilumab significantly restores skin barrier function and reduces inflammation ...
Mar 12, 2026
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Pediatric allergy specialist: Feed babies allergenic foods earlier, not later
In January 2026, the U.S. Department of Agriculture released new Dietary Guidelines for Americans, 2025–2030.
Mar 12, 2026
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Could a hot cup of matcha dial down the 'sneeze switch' in allergic rhinitis?
There's now another reason to love Japan's famous matcha: A study in mice suggests that the green tea powder could reduce the need to sneeze in people with nasal allergies.
Mar 11, 2026
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Experimental chemo drug triggers 'viral mimicry' signals that rally immune attack
In recent years, scientists have discovered that some chemotherapy drugs not only kill cancer cells directly, but at least in some patients, mysteriously also trigger their immune system to attack the cancer. That would seem ...
Mar 11, 2026
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