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Allergy and immunology news
Blocking immune 'signal two' expands gut tolerance cells, may open new IBD treatments
Weill Cornell Medicine investigators made an unexpected finding about how the immune system normally suppresses inappropriate chronic inflammation in the intestine, potentially opening new avenues for therapies against inflammatory ...
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Antibodies can selectively shut down harmful T cells without weakening whole immune system
The immune system is the frontline protection against infection, continually searching for and destroying unknown pathogens. While typical operation of the immune system scans for threats, some systems attack the body's own ...
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Machine learning predicts asthma risk in children with early-life atopic dermatitis
Machine learning models can predict the risk for developing moderate-to-severe persistent asthma and allergic rhinitis in children diagnosed with early-life atopic dermatitis, according to a study published online April 17 ...
21 hours ago
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How a chemical reaction triggers brain inflammation in Alzheimer's disease
The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in Alzheimer's disease, those immune cells are chronically overactivated, causing inflammation that ...
Apr 25, 2026
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Hidden in hair follicles, immune 'sentinel' cells may help skin detect microbes
Researchers at the School of Medicine at the University of California, Riverside have discovered previously unrecognized immune surveillance structures in the skin. Found within hair follicles, the cells resemble M (microfold) ...
Apr 25, 2026
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Protein's second role in inflammation could reshape treatment for Crohn's, arthritis and heart disease
A protein long understood to drive inflammation by producing nitric oxide has a second, previously unknown role—it physically binds to another key protein inside cells to directly modulate the immune response. The discovery, ...
Apr 24, 2026
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Inside lymph nodes, an overlooked cell type quietly directs immune battles in ways that could reshape medicine
The research group of prof. Sanjiv Luther at the department of immunobiology of the University of Lausanne has discovered that a fibroblast subtype is essential for coordinating certain immune cells within lymph nodes. This ...
Apr 23, 2026
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Autoantibody map uncovers body-wide immune attacks across Alzheimer's, Parkinson's and MS
Researchers at the University of São Paulo (USP) in Brazil discovered that neurodegenerative diseases, such as Alzheimer's, Parkinson's, and multiple sclerosis, are more complex than previously thought. Their analysis of ...
Apr 22, 2026
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How an anti-inflammatory drug helps the heart after a heart attack
Every day, thousands of people worldwide suffer a heart attack, often leading to lasting damage to the heart muscle. Recent research from the University of Oslo suggests that targeting inflammation in the body helps protect ...
Apr 22, 2026
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If you feel cranky and tired, you may have spring allergy fatigue
People might not associate brain fog and fatigue with spring allergies, but these symptoms can make life just as miserable—or sometimes more—than the watery eyes, itchy noses, and congestion we typically associate with reactions ...
Apr 22, 2026
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Study finds treating peanuts with cold plasma could make them less allergenic
Researchers at McGill University have found that briefly treating peanuts with cold plasma, an ionically charged gas that triggers chemical changes, reduces their potential to cause allergic reactions. The researchers say ...
Apr 22, 2026
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Cellular neighborhoods inside tumors may predict which patients with melanoma benefit from combination immunotherapy
A new UCLA Health Jonsson Comprehensive Cancer Center study suggests that the way immune cells are organized inside melanoma tumors may help researchers better understand which patients will benefit from combination immunotherapy ...
Apr 22, 2026
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B cells that fight infections may also boost muscle performance during exercise
B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific infections, remember them, and mount a targeted response by producing antibodies. A recent study ...
HIV's earliest immune battle leaves blood traces that forecast powerful antibodies years later
Some people living with HIV develop antibodies capable of neutralizing many different strains of the virus. New research links this to immune responses that occur early in infection. The findings, published in PLOS Pathogens, ...
Apr 21, 2026
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Inside tumors, immune cells hide a split personality—and one side could quietly decide cancer's fate
Macrophages, key regulators of tissue health and immune defense, are among the most abundant immune cells in solid tumors. Their role in cancer has been difficult to define because even closely related macrophage populations ...
Apr 21, 2026
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How immune cell networks drive liver disease
A type of rare T cell triggers a cascade of signals amplifying inflammation and ultimately leading to liver fibrosis, according to a new study from Julius Maximilian University of Würzburg published in Nature Communications. ...
Apr 21, 2026
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Early myocarditis onset after immunotherapy may predict treatment-related fatality
Patients who developed myocarditis within the first month of receiving immune checkpoint inhibitor therapy were more likely to die of myocarditis, and myocarditis-specific fatality was more common in patients who experienced ...
Apr 21, 2026
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Q&A: Why are women more likely to develop multiple sclerosis? A proteomics study provides clues
Knowing that women are diagnosed with multiple sclerosis (MS) at three times the rate of men, particularly during their 30s and 40s, scientists in the CU Anschutz lab of Kimberley Bruce, Ph.D., recently took that window of ...
Apr 21, 2026
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Cannabis may not be as anti-inflammatory as believed—research paints a more complex picture
Cannabis is no longer viewed solely as a recreational substance; it is increasingly recognized for its therapeutic potential. In many parts of the world, laws have evolved to include the use of cannabis for medical purposes. ...
Scientists map how HIV hijacks human cells—and how cells can fight back
The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body. Yet, even after decades of research on how the ...
Apr 20, 2026
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How to remove a metabolic tattoo: Scientists find protective mechanism in T cell purine pathways
While modern life includes many conveniences, humans are still incessantly exposed to a variety of metabolic stresses we have never experienced before. Our immune systems are constantly trying to protect us, and CD8⁺ T cells ...
Apr 20, 2026
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Protective 'switch' in most common blood cancer opens new doors for diagnosis and treatment
A new study published in The Journal of Immunology by researchers at the Josep Carreras Leukaemia Research Institute (IJC) has uncovered a crucial biological "off switch" in diffuse large B cell lymphoma (DLBCL), the most ...
Apr 20, 2026
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Robust flu protection may rely on B cells that are long-lived residents in the lungs
Deep in the lungs, resident memory B cells stand guard against influenza reinfection—but whether they remain there may depend on how strongly they are signaled through their own receptors. New research using an animal model ...
How mRNA cancer vaccines still destroy tumors when a key immune cell is missing
The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel Prize–winning technology is being adapted to fight cancer, with mRNA vaccines in clinical trials for melanoma, ...
Apr 18, 2026
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Cutting calories to slow aging—without compromising health
Restricting calorie intake in species such as mice, rhesus monkeys, and fruit flies has been shown to extend their lifespans. In some cases, these animals not only live longer, but are also free of disease. But when pushed ...
Apr 17, 2026
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