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Allergy and immunology news
First-in-class molecules dial down inflammation without compromising immunity
Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact—a long-sought goal in treating autoimmune diseases. The ...
16 hours ago
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Transcription factors form continuous 'circuit' that regulates T-cell exhaustion
Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion and migration during viral infection, which may inform future therapeutic strategies for managing ...
20 hours ago
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High‑fat diets linked to rapid decline in protective gut immune cells
In a preclinical study from Mass General Brigham, researchers have found that even short-term exposure to high levels of dietary fat results in a quick and selective loss of critical gut immune cells called ILC3s, promoting ...
17 hours ago
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New technique identifies proteins that trigger immune responses in transplants and implants
Mayo Clinic researchers have developed a new method to identify which proteins are most likely to trigger an immune response—a discovery that could help improve transplant care, regenerative medicine and other areas where ...
19 hours ago
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How to tell if spring symptoms owe to allergy, cold or something more serious
When your head is splitting, your nose is running nonstop, your eyes are itching and you're coughing, coughing, coughing, what's the best way to fight back? That depends on what's causing your symptoms, said Dr. Ian Tullberg, ...
Apr 6, 2026
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A natural molecule present in the human body protects against the flu
A research team led by the Fisabio Foundation has demonstrated that dermcidin, an antimicrobial peptide produced constitutively by the human body, also exhibits antiviral activity against the influenza virus. The study also ...
Apr 5, 2026
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Scientists map how the body traps 'sleeping' tuberculosis
Scientists at James Cook University have uncovered new insights into how the body contains latent tuberculosis, using a cutting-edge technique that allows researchers to map exactly where immune cells and bacteria interact ...
Apr 3, 2026
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A shift away from traditional antifungal research: Study points toward immune reprogramming to treat candidiasis
Systemic candidiasis is an opportunistic fungal infection that has been difficult to treat effectively. Research published in a paper in the April edition of Cell Host & Microbe suggests that immune metabolic reprogramming ...
Apr 3, 2026
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Looking back to protect the future: New insights into influenza immunity
A new study from the Peter Doherty Institute for Infection and Immunity shows that seasonal influenza vaccination does more than protect against viruses circulating that year; it can also prime the immune system to respond ...
Apr 2, 2026
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Reprogramming 'gatekeeper' immune cell may boost cancer immunotherapy
St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their energy production can ...
Apr 2, 2026
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World's largest study reveals new model to rule out penicillin allergy
Melbourne researchers have led the world's largest study confirming most patients labeled allergic to penicillin are not truly allergic. The study, described as a "game changer" by lead author Professor Jason Trubiano, demonstrates ...
Apr 2, 2026
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Studies tie altered regulatory T cells to autism-related behavior, point to potential therapies
Two new studies from the UC Davis MIND Institute examined regulatory T cells (Tregs) and their potential role in neuroinflammation and behavioral changes associated with autism. Tregs act as immune system "brakes," calming ...
Apr 2, 2026
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Feeling sniffly? New research suggests the immune system has its own daily cycle
New research led by Gregory Pearson, a doctoral student in the Department of Psychological and Brain Sciences in the College of Natural Sciences, reveals that the brain's immune defenses operate on a daily schedule, a finding ...
Apr 2, 2026
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Study finds third dose of COVID-19 vaccine is crucial for immunocompromised patients
Because the immune systems of people with inborn errors of immunity (IEI) don't function like everyone else's, it was unclear until now how well COVID-19 vaccinations protected them. In a new study, posted on the medRxiv ...
Apr 2, 2026
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Gut microbiota found to differ in children with rare food allergy
Children with the rare but serious allergic disease FPIES have an atypical gut microbiota compared to healthy children. This is shown in a new study from Umeå University, published in the journal the Journal of Allergy and ...
Apr 2, 2026
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How T cells amplify signals: New study reveals key molecular switch
Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be precisely amplified to mount an effective defense against invasive threats. New research by immunologists ...
Therapeutic, nasally delivered DNA vaccine fuses two genes to help fight tuberculosis
In a paper published in the Journal of Clinical Investigation, a research team at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health reports developing a therapeutic intranasal (nose-delivered) ...
Apr 1, 2026
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Small intestinal bacterial overgrowth linked to worsening symptoms in allergic diseases
Allergies are usually associated with the immune system, genetics, and environmental factors. Increasingly, however, another element is appearing in this puzzle: the gut microbiota. A review of studies published in the International ...
Apr 1, 2026
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Outcomes superior for endoscopic sinus surgery + Vidian neurectomy in allergic rhinitis with chronic rhinosinusitis
For patients with allergic rhinitis and chronic rhinosinusitis, the addition of vidian neurectomy to endoscopic sinus surgery (ESS) is associated with superior improvements in symptoms and nasal function, according to a study ...
Apr 1, 2026
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Cysteine pathways help T cells choose between multiplying and attacking tumors
A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health has discovered how the immune system's CD8+ T cells ...
Mar 31, 2026
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Scientists capture early stages of immune response inside cells
In new research, scientists at the Department of Energy's SLAC National Accelerator Laboratory, in collaboration with researchers at Harvard University and Brigham Young University, used the Stanford-SLAC Cryo-EM Center to ...
Mar 31, 2026
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Study maps hidden immune signals in type 1 diabetes
Type 1 diabetes researchers have made great progress in understanding the disease in the last two decades, even as a cure remains elusive. Now they have something that benefits any scientific effort. It's a map.
Mar 31, 2026
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Bacterial-like vaccine cues could help extend immunity against evolving viruses
Researchers at the University of Wisconsin School of Veterinary Medicine have identified a possible way to make longer-lasting vaccines for respiratory viruses like influenza and the coronavirus that causes COVID-19. The ...
Mar 31, 2026
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Spleen identified as new target in stroke recovery
Scientists have uncovered an important new link between the brain and immune system after stroke, which could lead to potential new treatments to improve recovery and reduce long-term disability. In new research published ...
Mar 31, 2026
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Reactivation of dormant regulatory T cells alleviates asthma symptoms in mice
A collaborative effort among researchers at the Henan Academy of Innovations in Medical Science, Zhengzhou University, and Shenzhen University School of Medicine has provided the first proof-of-principle study demonstrating ...
Mar 31, 2026
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