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Immunology news
Oncology & Cancer
Immune sabotage: How a Vitamin A byproduct compromises the body's normal anti-cancer response
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A—all-trans retinoic acid—compromises both the body's ...
Jan 6, 2026
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Genetics
Proximity matters: Claudin-1 as an unexpected guardian of central tolerance
Scientists from the Institute of Molecular Genetics of the Czech Academy of Sciences, in collaboration with the Faculty of Science at Charles University, have uncovered a completely new role for the protein Claudin-1 in the ...
Jan 5, 2026
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Lifting cancer's invisibility cloak: Dying tumor cells alert the immune system
The immune system provides constant surveillance for the body, aiming to spot and eliminate disease-causing microbes or cancerous cells. But tumor cells develop many features that help them hide from the immune system to ...
Jan 5, 2026
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High-dose risankizumab trial tests staying power against psoriasis
Oregon Medical Research Center in Portland, Oregon, has led a phase 2 trial in moderate-to-severe plaque psoriasis that paired higher-than-approved doses of risankizumab with extended follow-up and found high early skin clearance ...
Potential biomarker linked to multiple sclerosis progression and brain inflammation
A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs.
Jan 2, 2026
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Tumor bacteria linked to immunotherapy resistance in head and neck cancer
Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.
Jan 2, 2026
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A mother's circadian rhythm may predict her child's vulnerability to bacterial infection
In laboratory models, researchers at The University of Texas MD Anderson Cancer Center discovered that a mother's circadian rhythms, or internal body clock, can influence the immune system states of her offspring, which can ...
Jan 2, 2026
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Combination therapy for Burkitt's lymphoma dramatically improves cure rates in mice
Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most often in children and young adults. In recent years, CAR-T cell therapy—often referred to as a "living ...
Jan 2, 2026
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Loss of vitamin C synthesis protects animals from deadly schistosome infection
Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a benefit of vitamin C deficiency: protection from a major parasitic disease. Their research suggests an explanation for ...
Dec 30, 2025
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Brain immune cells may drive more damage in females than males with Alzheimer's
More than 7 million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester ...
Dec 30, 2025
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How pregnancy and breastfeeding enhance local immunity that cancer-proof the breast
For centuries, physicians observed that nuns, who are celibate, had much higher rates of breast cancer, leading to the theory that pregnancy, childbirth, and breastfeeding might be associated with lower breast cancer risk. ...
New antivirals are being tested for herpesviruses, and scientists now know how they work
Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.
Dec 29, 2025
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Melanoma cancer cells secrete extracellular vesicles to paralyze immune cells
A new international study led by Prof. Carmit Levy of the Department of Human Genetics and Biochemistry at the Gray Faculty of Medical & Health Sciences at Tel Aviv University finds that melanoma cancer cells paralyze immune ...
Dec 29, 2025
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Blocking a key gene regulator may restore immune response in cancer therapy
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target tumors. Despite their initial clinical success, many patients eventually experience diminished therapeutic ...
Dec 29, 2025
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Low-dose peanut therapy shown to protect children with peanut allergies
Children with peanut allergies may not need large doses of peanut oral immunotherapy (OIT) to build protection against peanuts, finds a new study led by The Hospital for Sick Children (SickKids) and Montreal Children's Hospital.
Dec 29, 2025
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Researchers turn cancer resistance mutations into targets for new immunotherapies
One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs that are initially effective lose their potency over time, as malignant cells acquire mutations ...
Dec 29, 2025
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Tattoos, toxins and the immune system—what you need to know before you get inked
From minimalist wrist designs to full sleeves, body art has become so common that it barely raises an eyebrow. But while the personal meaning of a tattoo may be obvious, the biological consequences are far less visible. Once ...
Dec 29, 2025
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Five new year's resolutions to help you breathe easier
Making resolutions for the new year?
Dec 29, 2025
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Scientists develop targeted therapy for T-cell lymphomas and leukemias
Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive ...
Dec 25, 2025
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Does being infected or vaccinated first influence COVID-19 immunity?
A new study analyzing the immune response to COVID-19 in a Catalan cohort of health workers sheds light on an important question: does it matter whether a person was first infected or first vaccinated?
Dec 23, 2025
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TIGIT protein inhibition could help immune system target cancer cells
Researchers at the University of Sharjah are exploring a promising approach that could enhance the immune system's ability to fight cancer, potentially paving the way for new treatments.
Dec 23, 2025
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Study reveals low immunity against H3N2 strain in Hong Kong: Early vaccination urged
Flu activity has surged in many parts of the Northern Hemisphere, driven primarily by a newly emerged H3N2 strain known as subclade K.
Dec 23, 2025
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A new strategy for immune tolerance: Engineered extracellular vesicles show promise
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific ...
Dec 22, 2025
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Eczema injectable drug provides quick itch relief, clinical trial results show
A recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.
Dec 20, 2025
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RNA steps outside the cell to help guide immune responses, study suggests
RNA is usually portrayed as a molecule that works deep inside the cell, helping to turn genetic information into proteins. But new research led by Utrecht University scientist Jack Li shows that RNA also plays an active role ...
Dec 19, 2025
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