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Allergy and immunology news
Not just drainage: Dural venous sinuses actively regulate brain immunity and fluid flow, study finds
National Institute of Neurological Disorders and Stroke investigators at the National Institutes of Health traced meningeal immune activity to dural venous sinuses that actively constrict and dilate, exchange fluid across ...
18 hours ago
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Study reveals why some immune disorders trigger severe food allergies, and others don't
A new study has shed light on why patients with certain rare immune disorders develop severe, food-triggered allergic reactions while others with similar diagnoses do not. The findings, published in the Journal of Experimental ...
13 hours ago
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A silent signaling network deep in the gut protects against inflammatory intestinal disorders, scientists find
Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem cells lining the gut wall are not just rebuilding tissue—they are listening and signaling. When ...
Newly found immune cells link strep throat to psoriasis
A common strep throat infection can trigger guttate psoriasis by altering the behavior of key immune cells, according to a new study from Karolinska Institutet published in eBioMedicine. The findings suggest how an infection ...
Feb 20, 2026
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Why chronic pain lasts longer in women: Immune cells offer clues
Chronic pain lasts longer for women than men, and new research suggests differences in hormone-regulated immune cells, called monocytes, may help explain why.
Feb 20, 2026
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Engineered CAR-NK cells appear more 'attack-ready'
Researchers at the Ribeirao Preto Blood Center and the Center for Cell-Based Therapy (CTC) conducted a study using the NK-92 cell line to test new models of chimeric antigen receptors (CARs) with specific costimulatory domains, ...
Feb 20, 2026
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Gene variants help explain why food allergies run in families
People often remark that allergies run in their family, but the genetic causes have remained unclear. Previous food allergy genetic research has relied upon broad but surface-level methods called genome-wide association studies.
Feb 20, 2026
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Epstein-Barr: The virus nearly everyone carries and its possible role in MS
Over 95% of the world's adult population is infected with Epstein-Barr virus (EBV), but most people never realize it. The infection often causes few symptoms and then stays in the body for life.
Feb 20, 2026
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Study reveals a specific genetic mismatch linked to life-threatening transplant complications
Umbilical cord blood transplantation has transformed the treatment options for patients with blood cancers and other life-threatening hematologic disorders, particularly when matched donors are unavailable. While cord blood ...
Feb 20, 2026
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Discovery could improve immune checkpoint inhibitor safety
For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar brand names. However, ...
Feb 20, 2026
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Study finds immune signature linked to treatment-resistant myasthenia gravis
Myasthenia gravis (MG) is a rare autoimmune disease in which the immune system attacks the connection between nerves and muscles. This attack causes muscle weakness that can affect vision, movement, speech, swallowing, and ...
Feb 20, 2026
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Closing in on a universal vaccine: Nasal spray protects mice from respiratory viruses, bacteria and allergens
In the realm of medical advancements, a universal vaccine that can protect against any pathogen has long been a Holy Grail—and about as elusive as a mythological vessel. But Stanford Medicine researchers and collaborators ...
Feb 19, 2026
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Mechanism behind immunotherapy resistance in lung cancer identified
Mayo Clinic researchers and collaborators have identified a previously unrecognized way lung tumors weaken the immune system, helping explain why many patients do not respond to immunotherapy and pointing to a potential new ...
Feb 19, 2026
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Remote-controlled CAR-T cells use venetoclax to disengage from tumors
Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers. Yet, despite their promise, CAR-T cells do ...
Feb 19, 2026
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Oral vaccine strategy used modified bacterium to combat colorectal cancer
A research team investigating the use of the bacterium Listeria monocytogenes against colorectal cancer has discovered a way to build a modified version of Listeria as an oral vaccine to prime the immune system directly within ...
Feb 19, 2026
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Macrophages need constant reminders to retain memories of prior infections, researchers discover
Researchers from the University of California, Los Angeles, have discovered that immune cells known as macrophages remain poised to fight repeat infections due to the persistent presence of signaling molecules left behind ...
Feb 18, 2026
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How age, sex and genetics shape our antibodies
Age, biological sex, and human genetic factors influence the production of antibodies during the immune response. A team of scientists from the Institut Pasteur, the CNRS and the Collège de France have shown that these factors ...
Feb 18, 2026
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Missing ANGPTL4 gene in mice reprograms immunity, shielding against gut inflammation
A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation. ...
Feb 18, 2026
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Vascularized liver tissueoid-on-a-chip models regeneration and transplant rejection
Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling ...
Feb 18, 2026
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NIH institute told to drop 'biodefense' and 'pandemic preparedness' language from website
As new infectious threats emerge worldwide, a key U.S. health agency is quietly stepping away from language tied to pandemic planning, a change some experts warn could leave Americans less protected when the next crisis hits.
Feb 18, 2026
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Mint, eucalyptus and chili compounds reveal powerful synergy against inflammation in immune cells
Many everyday foods and seasonings—such as herbs, spices, and aromatic plants—contain natural compounds called phytochemicals that can regulate inflammatory pathways. For centuries, these ingredients have been used together ...
Feb 17, 2026
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Allergic conjunctivitis linked to increased risk for keratoconus
For patients aged 5 to 25 years, allergic conjunctivitis is associated with an increased risk for keratoconus and increased corneal diagnostic procedures, according to a study published in the February issue of Contact Lens ...
Feb 17, 2026
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How vaccines give our immune systems a home advantage
We are now approaching six years since COVID-19 was declared a pandemic by the World Health Organization, yet talk of vaccines and our immune systems persists in our cultural conversations—from political arenas to the dinner ...
Feb 17, 2026
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Blocking both drug-resistant bacteria and influenza with a broad-spectrum infection prevention approach
Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine. In particular, mixed bacterial-viral infections in critically ill or immunocompromised ...
Feb 16, 2026
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Dual brakes on T-cells: New targets found to boost immunity in chronic infections
Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve treatments to control chronic ...
Feb 16, 2026
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