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Allergy and immunology news
Immune memory cells in ovarian cancer produce tumor-targeting antibodies, opening a vaccine path
While we tend to quickly forget having been ill or having received a vaccine, the immune system remembers remarkably well. It has memory B cells—"trained" immune cells that circulate throughout the body in search of harmful ...
3 hours ago
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How 'Pac-Man' cells fail to prevent deadly infection risk in people with cystic fibrosis
Researchers have discovered how part of the body's immune system could better combat a leading cause of death for people with cystic fibrosis (CF). A team led by The University of Queensland's Professor Peter Sly and Dr. ...
7 hours ago
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CAR T moves beyond cancer, targeting autoimmune disease with immune system reset
At age 49, Jan Janisch-Hanzlik's multiple sclerosis was destroying her freedom to live the life she wanted. She gave up her active nursing job for a desk role. Frequent falls made her afraid to carry her grandchildren. She ...
4 hours ago
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Mitochondria may control immune cell activation and the effectiveness of immunotherapy
A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial checkpoint that enables dendritic cells to efficiently activate T lymphocytes against viruses and ...
May 22, 2026
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COVID-19 mRNA vaccine plus immune system enhancer may reduce need for repeated boosters, say researchers
In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, improved the duration ...
May 22, 2026
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Key gene boundary discovery may improve treatment of rare inflammatory disorder
Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works. Researchers from Hiroshima University have identified a critical boundary within the immune-regulating gene ...
May 22, 2026
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Scientists capture 'housekeeping' immune cells attacking live melanoma
Scientists at the Garvan Institute of Medical Research have captured, for the first time, "housekeeping" immune cells actively attacking and engulfing live melanoma cells—a discovery that could change the way we approach ...
May 21, 2026
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Scientists discover how to harness T cells to combat entire viral families
Scientists at La Jolla Institute for Immunology (LJI) have discovered that combining key vaccine ingredients could give the body the tools it needs to fight the entire family of arenaviruses with a single vaccine. This "pan-arenavirus" ...
May 21, 2026
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Gut bacteria linked to immunotherapy success in melanoma patients
Researchers at The George Washington University, working with Weill Cornell Medicine, have identified specific gut bacteria linked to better responses to cancer immunotherapy in patients with advanced melanoma. The study ...
May 21, 2026
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Elite immune cells lead the fight against multiple myeloma
Immunotherapy for cancer works like a guided missile, directing the body's immune cells toward tumor cells. However, not all immune cells respond to the call to attack, and this can lead to variability in treatment responses. ...
May 21, 2026
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Pilot trial suggests anti-inflammatory drug could help difficult-to-treat depression
Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding from a University of Bristol-led pilot randomized controlled clinical trial, published in JAMA ...
May 20, 2026
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How dead tumor cells could make chemotherapy and radiotherapy work better
As tumors outgrow their blood and nutrient supplies, or respond to treatments like chemotherapy and radiotherapy, individual cancer cells die, exposing their internal scaffolds. These dead cells are an abundant source of ...
May 20, 2026
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New technique discovers previously unknown population of immune cells in the Alzheimer's brain
A newly developed microscopy technique allows, for the first time, the visualization of more than 30 protein markers simultaneously in the human brain and uses bioinformatics to analyze their spatial relationships. In the ...
May 20, 2026
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Study identifies key protein in immune cell exhaustion in cancer immunotherapy
CAR T-cell therapy is considered a milestone in personalized cancer treatment. In this approach, a patient's own immune cells are genetically modified to recognize and destroy tumor cells. While it has already shown impressive ...
May 19, 2026
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A new way to strengthen the body's defense against respiratory viruses
Researchers have discovered a new method to boost the body's natural ability to fight respiratory viruses, including respiratory syncytial virus (RSV), one of the leading causes of severe lung infections worldwide.
May 19, 2026
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Neutrophils manufacture schizophrenia-linked protein, according to new research
The most common white blood cells in your body—immune cells called neutrophils—can make a protein nobody knew they were making, Stanford Medicine investigators have discovered. That unexpected sighting joins a growing list ...
May 19, 2026
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Newly designed peptides suggest safer immunotherapies are within reach
Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important cellular messengers. Calcium signals help regulate muscle contraction, neural function, immune cell ...
May 19, 2026
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Nervous system helps lung cancer evade the immune system, study reveals
Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve ...
May 19, 2026
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Severe asthma links to three recurring illness clusters across 2,700 patients in 11 countries
Most people living with severe asthma are also battling other health conditions that go under the radar, a major new study has found. Researchers analyzing data from thousands of patients discovered that the additional illnesses—which ...
May 19, 2026
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How chemotherapy can backfire: An immune shift tied to tumor resistance and poorer outcomes
Chemotherapy can be life-saving for many patients, but not all tumors respond—and some that do, may eventually become resistant. Investigators at Houston Methodist have identified a possible explanation for this resistance, ...
May 18, 2026
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Researchers discover new clues to delaying type 1 diabetes
Thomas Delong, Ph.D., moved to Colorado from Germany two decades ago intent on one thing: understanding the origin of type 1 diabetes (T1D) and finding ways to stop it. Diagnosed at age 12 with the disease that affects 9.5 ...
May 18, 2026
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Links discovered between mitochondrial lipid deficiency and inflammation of the gut
Inflammatory bowel diseases occur when the delicate balance between the gut, the immune system, and the microbiota is disrupted. Until now, however, it was unclear whether harmful microbes or defects in the body's own immune ...
May 18, 2026
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Reversing T cell exhaustion improves effectiveness of myeloma immunotherapies
Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb, and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma. In two ...
May 18, 2026
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How lungs balance defense and damage by tuning responses to deeper threats
Barrier organs that form boundaries between the body and the outside environment, such as the lungs, skin, and intestines, face a difficult balancing act. They must respond quickly to threats such as infection, but they also ...
May 16, 2026
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Neuronal hyperactivity triggers severe autoimmune brain disorder, researchers discover
In a condition known as "IgLON5 encephalitis," the immune system mistakenly attacks cells in the brain. This leads to brain inflammation and neuronal damage, which can manifest as sleep disturbances, cognitive impairment, ...
May 15, 2026
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