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Immunology news
Immunology
Isolated gut microbe drives stronger responses to cancer therapy
The National Cancer Center Research Institute in Tokyo reports that a newly isolated gut bacterium, designated Hominenteromicrobium strain YB328, mobilizes specialized dendritic cells to strengthen the impact of PD-1 blockade ...
19 hours ago
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In-body CAR-T cell generation proves effective, safe in mice study
mRNA bundled in lipid nanoparticles trains T cells in mice to eliminate cancer. Coupled with noninvasive imaging, researchers tracked the in situ CAR-T cells to assess their effectiveness and safety.
13 hours ago
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A new framework for understanding and tackling CAR T toxicities
Immunotherapy using CAR T cells is finding ever more applications. In addition to their use in the treatment of blood and lymphatic cancers, CAR T cells are now also being investigated for solid tumors and various autoimmune ...
16 hours ago
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An aggressive childhood cancer case opens new avenues for advanced cell therapies
Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs. Approximately ...
17 hours ago
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Measles isn't just dangerous, it may erase your immune system
Blindness, pneumonia, severe diarrhea and even death—measles virus infections, especially in children, can have devastating consequences. Fortunately, we have a safe and effective defense. Measles vaccines are estimated ...
13 hours ago
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Penicillin allergy testing needed to fight antibiotic resistance
Penicillins are first-choice antibiotics for many common infections, but more than one in 15 UK adults have a penicillin allergy label on their medical records. In the event of an infection, they will be prescribed alternative ...
Jul 15, 2025
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Blood stem cell metabolism tracked through aging and cancer development
Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zurich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, ...
Jul 15, 2025
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Cancer drug shows promise as treatment for blindness
Singapore researchers have discovered that a new cancer drug, originally developed at A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB), shows potential as a new treatment approach for two leading causes of blindness ...
Jul 15, 2025
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AI-based tool can 'measure' cancer aggressiveness and paves the way for new therapies
As cancer cases have increased worldwide, the disease has become more complex, presenting challenges to scientific advances in diagnosis and treatment. In this context, artificial intelligence (AI) has emerged as a valuable ...
Jul 15, 2025
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Defensins are tiny proteins with strong antiviral possibilities in disease prevention and treatment
Viruses and bacteria are always trying to sneak into our bodies, but researchers at the University of Missouri are discovering that our own biology may already hold the keys to fighting off some of the deadliest infectious ...
Jul 15, 2025
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Review suggests ending adult boosters for tetanus, diphtheria
The United States could safely drop tetanus and diphtheria booster shots for adults and save an estimated $1 billion a year, according to a new review led by researchers at Oregon Health & Science University.
Jul 15, 2025
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Blocking little-known protein may offer hope for devastating lung disease
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring ...
Jul 15, 2025
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New route into cells could make gene therapies safer
Scientists from the Centenary Institute and the University of Sydney have made a landmark discovery that could lead to safer and more effective gene therapies for a range of serious genetic disorders including Duchenne muscular ...
Jul 15, 2025
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Controlled physical barrier created to boost cancer immunotherapy
A study led by Prof. Liang Xingjie's team from the National Center for Nanoscience and Technology of the Chinese Academy of Sciences (CAS) reported a biomimetic physical barrier (BPB) that temporarily blocks T cell-tumor ...
Jul 15, 2025
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High dietary inflammatory index tied to increased prevalence of eczema
High dietary inflammatory index (DII), which quantifies the inflammatory potential of diet, is associated with increased prevalence of atopic dermatitis (AD), according to a study published online June 19 in Frontiers of ...
Jul 15, 2025
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Plant compound slows cervical cancer growth in preclinical model
Cervical cancer is one of the most common gynecologic cancers worldwide and continues to be a leading cause of cancer-related death in women. While early detection through screening has improved outcomes, treatment options ...
Jul 15, 2025
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Immunotherapy resistance linked to cytoplasmic WEE1 protein
Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues. Some cancer cells exploit these checkpoints to avoid immune detection. Immune checkpoint blockade (ICB)—a therapy ...
Jul 15, 2025
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Chronic hives: Researchers identify most effective, safest treatments
A new international study led by researchers at McMaster University has identified the most effective and safest treatments for people suffering from chronic urticaria, more commonly known as chronic hives.
Jul 15, 2025
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Dropscreen, ViewAllergy39 not equally effective for detecting allergens, study finds
DropScreen (DS) and ViewAllergy39 (VA) are not equally effective for detecting specific immunoglobulin (Ig) E involved in pollinosis, according to a study published online in the Journal of Immunoassay and Immunochemistry.
Jul 15, 2025
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New study reveals promising strategy to retrain neutrophils to target breast cancer
A new study conducted by researchers from McGill University, the Lady Davis Institute for Medical Research (LDI) at the Jewish General Hospital, Princess Margaret Cancer Center and MIT has identified a novel approach to combat ...
Jul 14, 2025
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New blood test predicts multiple sclerosis risk years before symptoms appear
A research team at the Medical University of Vienna has developed a blood test that allows the identification of individuals at risk for developing multiple sclerosis (MS) with a high degree of certainty years before the ...
Jul 14, 2025
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New AI system uncovers hidden cell subtypes, boosts precision medicine
In order to produce effective targeted therapies for cancer, scientists need to isolate the genetic and phenotypic characteristics of cancer cells, both within and across different tumors, because those differences impact ...
Jul 14, 2025
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Fighting leukemia by breaking a hidden cell loop
Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells—and developed a novel immunotherapy that can disrupt that loop to boost immune function ...
Jul 14, 2025
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New insights into malaria: Proteins in the blood can reveal the severity of the disease
Researchers at Karolinska Institutet have identified over 250 proteins that are strongly affected by malaria, which could help predict the severity of the disease and thus enable faster treatment for the most critical patients.
Jul 14, 2025
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