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Immunology news
Immunology
Surprising finding could pave way for universal cancer vaccine
An experimental mRNA vaccine has boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system ...
Jul 18, 2025
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Oncology & Cancer
Novel complex induces immunogenic cancer cell death
Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something ...
Jul 18, 2025
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Newly discovered compounds help cells fight a wide range of viruses
Researchers at MIT and other institutions have identified compounds that can fight off viral infection by activating a defense pathway inside host cells. These compounds, they believe, could be used as antiviral drugs that ...
Jul 17, 2025
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Researchers develop novel antibody-RNA therapy for resistant cancers
A specially engineered antibody that can accurately deliver RNA treatments into hard-to-reach and hard-to-treat tumors significantly improved survival and reduced tumor sizes in animal models, according to a study reported ...
Jul 17, 2025
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Study shows gene 'switches' can be edited to influence inflammation
Controlling the activity of specific genes in the laboratory through the editing of their epigenetic marks is now a reality thanks to the CRISPR technology. A team from the Josep Carreras Leukemia Research Institute has demonstrated ...
Jul 17, 2025
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Lung injury recovery: PAR1 protein triggers lymphatic vessel changes for better fluid clearance
A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine. Injury—whether by infection, ...
Jul 17, 2025
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Scientists discover genetic condition that causes paralysis following mild infections
Doctors and genetic researchers at The University of Manchester have discovered that changes in a gene leads to severe nerve damage in children following a mild bout of infection.
Jul 17, 2025
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How lung repair mechanisms can help fight against tuberculosis
New research has found that delivering a stronger form of the tuberculosis vaccine directly to the lungs can help generate protective immune cells to help fight the disease. The research is published in the journal Mucosal ...
Jul 17, 2025
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Isolated gut microbe drives stronger responses to cancer therapy
The National Cancer Center Research Institute in Tokyo reports that a newly isolated gut bacterium, designated Hominenteromicrobium strain YB328, mobilizes specialized dendritic cells to strengthen the impact of PD-1 blockade ...
Environment near breast cancer tumors may hold key information for prognosis
Cells and tissues surrounding a breast cancer tumor may hold critical information about how patients will respond to treatment, according to a new study from Johns Hopkins University.
Jul 16, 2025
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In-body CAR-T cell generation proves effective, safe in mice study
mRNA bundled in lipid nanoparticles trains T cells in mice to eliminate cancer. Coupled with noninvasive imaging, researchers tracked the in situ CAR-T cells to assess their effectiveness and safety.
Jul 16, 2025
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A new framework for understanding and tackling CAR T toxicities
Immunotherapy using CAR T cells is finding ever more applications. In addition to their use in the treatment of blood and lymphatic cancers, CAR T cells are now also being investigated for solid tumors and various autoimmune ...
Jul 16, 2025
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An aggressive childhood cancer case opens new avenues for advanced cell therapies
Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs. Approximately ...
Jul 16, 2025
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Measles isn't just dangerous, it may erase your immune system
Blindness, pneumonia, severe diarrhea and even death—measles virus infections, especially in children, can have devastating consequences. Fortunately, we have a safe and effective defense. Measles vaccines are estimated ...
Jul 16, 2025
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Penicillin allergy testing needed to fight antibiotic resistance
Penicillins are first-choice antibiotics for many common infections, but more than one in 15 UK adults have a penicillin allergy label on their medical records. In the event of an infection, they will be prescribed alternative ...
Jul 15, 2025
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Cancer drug shows promise as treatment for blindness
Singapore researchers have discovered that a new cancer drug, originally developed at A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB), shows potential as a new treatment approach for two leading causes of blindness ...
Jul 15, 2025
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Blood stem cell metabolism tracked through aging and cancer development
Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zurich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, ...
Jul 15, 2025
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Defensins are tiny proteins with strong antiviral possibilities in disease prevention and treatment
Viruses and bacteria are always trying to sneak into our bodies, but researchers at the University of Missouri are discovering that our own biology may already hold the keys to fighting off some of the deadliest infectious ...
Jul 15, 2025
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AI-based tool can 'measure' cancer aggressiveness and paves the way for new therapies
As cancer cases have increased worldwide, the disease has become more complex, presenting challenges to scientific advances in diagnosis and treatment. In this context, artificial intelligence (AI) has emerged as a valuable ...
Jul 15, 2025
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Review suggests ending adult boosters for tetanus, diphtheria
The United States could safely drop tetanus and diphtheria booster shots for adults and save an estimated $1 billion a year, according to a new review led by researchers at Oregon Health & Science University.
Jul 15, 2025
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Blocking little-known protein may offer hope for devastating lung disease
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring ...
Jul 15, 2025
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New route into cells could make gene therapies safer
Scientists from the Centenary Institute and the University of Sydney have made a landmark discovery that could lead to safer and more effective gene therapies for a range of serious genetic disorders including Duchenne muscular ...
Jul 15, 2025
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Controlled physical barrier created to boost cancer immunotherapy
A study led by Prof. Liang Xingjie's team from the National Center for Nanoscience and Technology of the Chinese Academy of Sciences (CAS) reported a biomimetic physical barrier (BPB) that temporarily blocks T cell-tumor ...
Jul 15, 2025
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Immunotherapy resistance linked to cytoplasmic WEE1 protein
Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues. Some cancer cells exploit these checkpoints to avoid immune detection. Immune checkpoint blockade (ICB)—a therapy ...
Jul 15, 2025
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High dietary inflammatory index tied to increased prevalence of eczema
High dietary inflammatory index (DII), which quantifies the inflammatory potential of diet, is associated with increased prevalence of atopic dermatitis (AD), according to a study published online June 19 in Frontiers of ...
Jul 15, 2025
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