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Immunology news

Immunology

Soft drinks can affect communication of gut bacteria and immune system

Consumption of soft drinks, supplemented with white sugar, alters the DNA of gut bacteria and affects the host immune system. The good news? These effects are reversible.

Medical research

Study reveals how immune cells transform to aid tissue healing after injury

Regulatory T cells (Treg cells) are a specialized subgroup of immune cells that play a central role in the human immune system. These cells can suppress erroneous and therefore harmful immune reactions that can lead to autoimmune ...

Immunology

Surprising finding could pave way for universal cancer vaccine

An experimental mRNA vaccine has boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system ...

Oncology & Cancer

Novel complex induces immunogenic cancer cell death

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something ...

Diseases, Conditions, Syndromes

How lung repair mechanisms can help fight against tuberculosis

New research has found that delivering a stronger form of the tuberculosis vaccine directly to the lungs can help generate protective immune cells to help fight the disease. The research is published in the journal Mucosal ...

Oncology & Cancer

A new framework for understanding and tackling CAR T toxicities

Immunotherapy using CAR T cells is finding ever more applications. In addition to their use in the treatment of blood and lymphatic cancers, CAR T cells are now also being investigated for solid tumors and various autoimmune ...

Diseases, Conditions, Syndromes

Measles isn't just dangerous, it may erase your immune system

Blindness, pneumonia, severe diarrhea and even death—measles virus infections, especially in children, can have devastating consequences. Fortunately, we have a safe and effective defense. Measles vaccines are estimated ...

Immunology

Penicillin allergy testing needed to fight antibiotic resistance

Penicillins are first-choice antibiotics for many common infections, but more than one in 15 UK adults have a penicillin allergy label on their medical records. In the event of an infection, they will be prescribed alternative ...

Immunology

Cancer drug shows promise as treatment for blindness

Singapore researchers have discovered that a new cancer drug, originally developed at A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB), shows potential as a new treatment approach for two leading causes of blindness ...

Oncology & Cancer

Anticancer drugs could make immunotherapies more effective

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.

Diseases, Conditions, Syndromes

How SARS-CoV-2 exploits human proteins to replicate

Researchers at Karolinska Institutet have discovered how the SARS-CoV-2 virus, which causes COVID-19, manipulates human proteins to replicate and evade the immune system. The results have been published in Nature Communications.

Immunology

Developing a chip to measure immunity

Every winter, influenza returns with a new variant. People who have previously been infected with or vaccinated against flu may have some protection, but this depends on how well their immune system's "memory" of the previous ...

Oncology & Cancer

How breast cancer cells survive in bone marrow after remission

A study from researchers at the University of Michigan and the University of California San Diego has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow ...

Oncology & Cancer

Enzyme identified as new therapeutic target for 'cold' tumors

A study from the University of Michigan Health Rogel Cancer Center may have—at last—cracked the cold case of immunotherapy resistance. The research, led by Arul M. Chinnaiyan, M.D., Ph.D., identifies the UBA1 enzyme, ...

Oncology & Cancer

Researchers design novel immunotherapy for brain cancer

The Wistar Institute's David B. Weiner, Ph.D.—Executive Vice President, director of the Vaccine & Immunotherapy Center and W.W. Smith Charitable Trust Distinguished Professor in Cancer Research—and his lab have successfully ...

Medical research

Unique experiment sends T-cells into space

On 26 November, an experiment in a sounding rocket was launched at Esrange Space Center in Kiruna, Sweden, by a research group at the Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet.