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Immunology news
Immunology
Lymphoid-derived dendritic cells found to shape immune suppression and allergy responses
Lymphoid-derived conventional dendritic cells (L-cDCs) may play a unique function associated with immune suppression and allergy induction, as reported by researchers from Japan. Long thought to arise only from myeloid lineages, ...
3 minutes ago
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Immunology
Study uncovers how the immune system fends off gut parasites
New research from the University of Pittsburgh reveals how the immune system defends against intestinal parasitic worms, or helminths, one of the most common infections worldwide in communities with limited access to clean ...
2 hours ago
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Radiation therapy overcomes immunotherapy resistance in some cancers
By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators ...
6 hours ago
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Study identifies world-first treatments to prevent a life-threatening virus infection
Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.
6 hours ago
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New insights into the immune system's crucial role in wound healing
An enzyme expressed by skin cells could be helpful in the management of non-healing skin wounds and ulcers, according to research by University of Manchester and Singapore's A*STAR Skin Research Lab scientists.
3 hours ago
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Protein switch behind stubborn lung cancers offers new treatment target
Scientists have uncovered a molecular "on–off" switch that helps lung adenocarcinoma—the most common form of lung cancer—grow and spread. The discovery pinpoints the protein calcyclin‑binding protein (CACYBP) as a ...
3 hours ago
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Soft drinks can affect communication of gut bacteria and immune system
Consumption of soft drinks, supplemented with white sugar, alters the DNA of gut bacteria and affects the host immune system. The good news? These effects are reversible.
Jul 21, 2025
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Study reveals how immune cells transform to aid tissue healing after injury
Regulatory T cells (Treg cells) are a specialized subgroup of immune cells that play a central role in the human immune system. These cells can suppress erroneous and therefore harmful immune reactions that can lead to autoimmune ...
Jul 21, 2025
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Immune cells turn into 'mini-Hulks' to push away tissue and make space when migrating
Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable three-dimensional tissues that make up our bodies.
Jul 21, 2025
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Researchers engineer rare immune cells to create powerful new cancer vaccine
In a new study published in Cancer Immunology Research, scientists at the Icahn School of Medicine at Mount Sinai have developed a novel method to generate billions of rare immune cells known as conventional type I dendritic ...
Jul 21, 2025
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Paper-based device detects immune defects in 10 minutes with high accuracy
A 3D paper-based analytical device (3D-osPAD) with in situ gold signal amplification enables one-step, highly sensitive detection of anti-IFN-γ autoantibodies within 10 minutes, showing 10-fold improved sensitivity and high ...
Jul 21, 2025
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Surprising finding could pave way for universal cancer vaccine
An experimental mRNA vaccine has boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system ...
Jul 18, 2025
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Novel complex induces immunogenic cancer cell death
Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something ...
Jul 18, 2025
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Researchers develop novel antibody-RNA therapy for resistant cancers
A specially engineered antibody that can accurately deliver RNA treatments into hard-to-reach and hard-to-treat tumors significantly improved survival and reduced tumor sizes in animal models, according to a study reported ...
Jul 17, 2025
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Newly discovered compounds help cells fight a wide range of viruses
Researchers at MIT and other institutions have identified compounds that can fight off viral infection by activating a defense pathway inside host cells. These compounds, they believe, could be used as antiviral drugs that ...
Jul 17, 2025
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Study shows gene 'switches' can be edited to influence inflammation
Controlling the activity of specific genes in the laboratory through the editing of their epigenetic marks is now a reality thanks to the CRISPR technology. A team from the Josep Carreras Leukemia Research Institute has demonstrated ...
Jul 17, 2025
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Lung injury recovery: PAR1 protein triggers lymphatic vessel changes for better fluid clearance
A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine. Injury—whether by infection, ...
Jul 17, 2025
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Scientists discover genetic condition that causes paralysis following mild infections
Doctors and genetic researchers at The University of Manchester have discovered that changes in a gene leads to severe nerve damage in children following a mild bout of infection.
Jul 17, 2025
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How lung repair mechanisms can help fight against tuberculosis
New research has found that delivering a stronger form of the tuberculosis vaccine directly to the lungs can help generate protective immune cells to help fight the disease. The research is published in the journal Mucosal ...
Jul 17, 2025
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Isolated gut microbe drives stronger responses to cancer therapy
The National Cancer Center Research Institute in Tokyo reports that a newly isolated gut bacterium, designated Hominenteromicrobium strain YB328, mobilizes specialized dendritic cells to strengthen the impact of PD-1 blockade ...
Environment near breast cancer tumors may hold key information for prognosis
Cells and tissues surrounding a breast cancer tumor may hold critical information about how patients will respond to treatment, according to a new study from Johns Hopkins University.
Jul 16, 2025
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In-body CAR-T cell generation proves effective, safe in mice study
mRNA bundled in lipid nanoparticles trains T cells in mice to eliminate cancer. Coupled with noninvasive imaging, researchers tracked the in situ CAR-T cells to assess their effectiveness and safety.
Jul 16, 2025
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A new framework for understanding and tackling CAR T toxicities
Immunotherapy using CAR T cells is finding ever more applications. In addition to their use in the treatment of blood and lymphatic cancers, CAR T cells are now also being investigated for solid tumors and various autoimmune ...
Jul 16, 2025
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An aggressive childhood cancer case opens new avenues for advanced cell therapies
Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs. Approximately ...
Jul 16, 2025
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Measles isn't just dangerous, it may erase your immune system
Blindness, pneumonia, severe diarrhea and even death—measles virus infections, especially in children, can have devastating consequences. Fortunately, we have a safe and effective defense. Measles vaccines are estimated ...
Jul 16, 2025
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