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Immunology news
Diseases, Conditions, Syndromes
Allogeneic HCT feasible in older patients with myelodysplastic syndrome
Allogeneic hematopoietic cell transplantation (allo-HCT) is feasible in older patients with myelodysplastic syndrome (MDS), according to a study published online June 26 in the European Journal of Haematology.
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Health
Immunity to seasonal flu protects against severe illness from bird flu in ferrets, research reveals
The fatality rate for H5N1 highly pathogenic avian influenza in humans has historically been high, with more than half of people dying. Why, then, is the current H5N1 bird flu outbreak—which has caused massive die-offs ...
2 hours ago
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Study finds immune cells undermine cancer therapy by triggering their own death
A team of Memorial Sloan Kettering Cancer Center (MSK) researchers have made an important finding about why genetically engineered immune cells sometimes fail to finish the job when given as a cancer treatment. The new discovery ...
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New drug strategy blocks cancer cells' adaptation, doubling chemotherapy effectiveness
In a wholly new approach to cancer treatment, Northwestern University biomedical engineers have doubled the effectiveness of chemotherapy in animal experiments.
13 hours ago
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Patients' own autoantibodies may hold key to boosting cancer immunotherapy response
A new study has revealed that autoantibodies—immune proteins traditionally associated with autoimmune disease—may profoundly influence how cancer patients respond to immunotherapy.
5 hours ago
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Study uncovers how the immune system fends off gut parasites
New research from the University of Pittsburgh reveals how the immune system defends against intestinal parasitic worms, or helminths, one of the most common infections worldwide in communities with limited access to clean ...
Jul 22, 2025
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Radiation therapy overcomes immunotherapy resistance in some cancers
By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators ...
Jul 22, 2025
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Study identifies world-first treatments to prevent a life-threatening virus infection
Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.
Jul 22, 2025
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Unique immune cell linked to aggressive leukemia may lead to improved treatment outcomes
A new study by Indiana University School of Medicine researchers has revealed a breakthrough in the fight against acute myeloid leukemia, one of the most aggressive and fatal blood cancers in adults. The discovery of a previously ...
Jul 22, 2025
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Lymphoid-derived dendritic cells found to shape immune suppression and allergy responses
Lymphoid-derived conventional dendritic cells (L-cDCs) may play a unique function associated with immune suppression and allergy induction, as reported by researchers from Japan. Long thought to arise only from myeloid lineages, ...
Jul 22, 2025
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Cancer-fighting radioisotope being optimized for therapeutic use
A promising breakthrough in cancer treatment is taking shape at the University of Missouri Research Reactor (MURR), where scientists are developing a powerful radioisotope that could one day precisely target and destroy cancer ...
Jul 22, 2025
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New insights into the immune system's crucial role in wound healing
An enzyme expressed by skin cells could be helpful in the management of non-healing skin wounds and ulcers, according to research by University of Manchester and Singapore's A*STAR Skin Research Lab scientists.
Jul 22, 2025
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Protein switch behind stubborn lung cancers offers new treatment target
Scientists have uncovered a molecular "on–off" switch that helps lung adenocarcinoma—the most common form of lung cancer—grow and spread. The discovery pinpoints the protein calcyclin‑binding protein (CACYBP) as a ...
Jul 22, 2025
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Soft drinks can affect communication of gut bacteria and immune system
Consumption of soft drinks, supplemented with white sugar, alters the DNA of gut bacteria and affects the host immune system. The good news? These effects are reversible.
Jul 21, 2025
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Study reveals how immune cells transform to aid tissue healing after injury
Regulatory T cells (Treg cells) are a specialized subgroup of immune cells that play a central role in the human immune system. These cells can suppress erroneous and therefore harmful immune reactions that can lead to autoimmune ...
Jul 21, 2025
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Immune cells turn into 'mini-Hulks' to push away tissue and make space when migrating
Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable three-dimensional tissues that make up our bodies.
Jul 21, 2025
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Researchers engineer rare immune cells to create powerful new cancer vaccine
In a new study published in Cancer Immunology Research, scientists at the Icahn School of Medicine at Mount Sinai have developed a novel method to generate billions of rare immune cells known as conventional type I dendritic ...
Jul 21, 2025
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Paper-based device detects immune defects in 10 minutes with high accuracy
A 3D paper-based analytical device (3D-osPAD) with in situ gold signal amplification enables one-step, highly sensitive detection of anti-IFN-γ autoantibodies within 10 minutes, showing 10-fold improved sensitivity and high ...
Jul 21, 2025
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Surprising finding could pave way for universal cancer vaccine
An experimental mRNA vaccine has boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system ...
Jul 18, 2025
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Novel complex induces immunogenic cancer cell death
Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something ...
Jul 18, 2025
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Newly discovered compounds help cells fight a wide range of viruses
Researchers at MIT and other institutions have identified compounds that can fight off viral infection by activating a defense pathway inside host cells. These compounds, they believe, could be used as antiviral drugs that ...
Jul 17, 2025
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Researchers develop novel antibody-RNA therapy for resistant cancers
A specially engineered antibody that can accurately deliver RNA treatments into hard-to-reach and hard-to-treat tumors significantly improved survival and reduced tumor sizes in animal models, according to a study reported ...
Jul 17, 2025
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Study shows gene 'switches' can be edited to influence inflammation
Controlling the activity of specific genes in the laboratory through the editing of their epigenetic marks is now a reality thanks to the CRISPR technology. A team from the Josep Carreras Leukemia Research Institute has demonstrated ...
Jul 17, 2025
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Lung injury recovery: PAR1 protein triggers lymphatic vessel changes for better fluid clearance
A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine. Injury—whether by infection, ...
Jul 17, 2025
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Scientists discover genetic condition that causes paralysis following mild infections
Doctors and genetic researchers at The University of Manchester have discovered that changes in a gene leads to severe nerve damage in children following a mild bout of infection.
Jul 17, 2025
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